Alterations in Some Haematological Parameters of The African Snakehead: Parachanna africans Exposed to Cadmium

The haematological alterations produced on exposure of the African snakehead, Parachanna africans to the sublethal concentration (0.0, 0.1, 1.0 and 10.0 mg/L) of cadmium (Cd2+) for 21 days have been studied. Red blood cell (RBC) count, haemoglobin (Hb) concentration, haematocrit (Hct), the mean corpuscular haemoglobin (MCH) and the mean corpuscular volume (MCV) levels were decreased with an increase in exposure concentration, but the level of the mean corpuscular haemoglobin concentration (MCHC) was increased. These alterations could be attributed to haemolysis and impairment of haemoglobin synthesis, resulting in a hypochromic microcytic anaemia, induced by exposure to cadmium. Cadmium exposure also caused significant decreases in white blood cell (WBC) count. The primary consequence of the observed changes in total and differential leucocyte counts in stressed fish was attributed to suppression of the immune system and increased susceptibility to disease. Plasma glucose and total plasma protein concentrations were significantly decreased; showing that cadmium affects the fish energy metabolism. The present study thus confirmed that haematological parameters are very sensitive indicators of fish organism response to chemicals in this case cadmium.

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Haematological parameters of apparently healthy neonates at the Federal Medical Centre Bida, North Central Nigeria

Annals of Health Research ◽

10.30442/ahr.0603-04-90 ◽

2020 ◽

Vol 6 (3) ◽

pp. 276-286

Author(s):

OE Ojewole ◽

U Abubakar ◽

AO Olowu

Keyword(s):

Blood Cell ◽

Venous Blood ◽

Haemoglobin Concentration ◽

Screening Tools ◽

Haematological Parameters ◽

Corpuscular Haemoglobin ◽

Treatment Objective ◽

Mean Corpuscular Haemoglobin ◽

The Mean ◽

Apparently Healthy

Background: Haematological parameters are used as screening tools for patient’s care and treatment. Objective: To determine the haematological parameters of apparently healthy term Nigerian babies and generate normative data. Methods: This was a descriptive, longitudinal study of consecutively recruited babies. The haematological parameters were determined using venous blood samples drawn at delivery and on the 14th day of life using a haematology auto-analyser. Results: Of the 309 babies recruited on the first day of life, 160 (51.8%) were males while 149 (48.2%) were females. Two hundred and seventy-nine (90.3%) were delivered vaginally. Most (75%) of the neonates were of Nupe origin. The mean haematocrit, haemoglobin concentration, Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH), Mean Corpuscular Haemoglobin Concentration (MCHC), Red Blood Cell and reticulocyte count on Day 1 were 48.8±8.0%, 15.0±2.6g/dl, 104.1±8.8fl, 31.9±3.3pg, 30.7±1.7g/dl, 4.7±0.9 (×109/l) and 2.0±1.4% respectively. Corresponding Day 14 values were 41.2±5.2%, 12.8±1.9g/dl, 97.2±9.8fl, 30.3±3.8pg, 31.1±1.7g/dl, 4.5±0.6 (×109/l) and 1.0±0.7% respectively. The mean White Blood Cell (WBC) and platelet counts were 13.3±4.8 (×109/l) and 228.3±81.2 (×109/l) respectively, on the 1st day of life and 10.1±2.4 (×109/l) and 370.1±120.7 (×109/l) respectively on the 14th day. The mean differential WBC counts were 49.4±12.0% for neutrophils and 37.4±11.3% for lymphocytes on the 1st day and 32.4±10.0% and 52.8±9.3% respectively on the 14th day. Conclusion: Neonates from Bida have haematological parameters comparable with previously reported values from other parts of Nigeria.

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Haematological Profiles of Pigs on Different Farms Reflect Their Health Status

10.21203/rs.3.rs-644732/v1 ◽

2021 ◽

Author(s):

Irena Golinar Oven ◽

Alenka Nemec Svete ◽

Melita Hajdinjak ◽

Jan Plut ◽

Marina Stukelj

Keyword(s):

Health Status ◽

Blood Cell ◽

Cell Count ◽

White Blood Cell ◽

Haemoglobin Concentration ◽

Haematological Parameters ◽

Blood Cell Count ◽

Blood Samples ◽

Corpuscular Haemoglobin ◽

Mean Corpuscular Haemoglobin

Abstract BackgroundHaematological examination is an important diagnostic tool in the assessment of pig health status. The present study aimed to assess haematological parameters in pigs of different age categories from six farrow-to-finish farms differing in herd health status. The following pig categories were included: 5 age groups of growers (5, 7, 9–10, 11 and 12–13 weeks-old), fatteners and breeding pregnant sows. Individual blood samples for determining complete blood count and white blood cell differential count were taken and group samples of oral fluid and faeces were collected from each animal category in each of the six farms and tested for the detection of Porcine Circovirus Type 2 (PCV2), Porcine Reproductive and Respiratory Virus (PRRSV), and Hepatitis E Virus (HEV) using PCR, RT-PCR, and qRT-PCR protocols. Individual blood samples were analysed using an automated laser-based haematology analyser. The following haematological parameters were reported: white blood cell count (WBC), red blood cell count (RBC), haemoglobin concentration (Hb), haematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), platelet count (PLT), and percentage and number of neutrophils, lymphocytes, monocytes, eosinophils, basophils, and "large unstained cells" - LUCs. ResultsOn farms free of PRRSV, PCV2 and HEV, age had significant effect on the following parameters: WBC, Hb, MCH, MCHC, PLT, percentage of neutrophils, lymphocytes and eosinophils and absolute numbers of neutrophils, lymphocytes, monocytes, basophils and LUCs. On farms with PRRS, PCV2 and/or HEV, age significantly affected all observed blood parameters except the percentage of LUCs. The percentages of lymphocytes, MCV and Hct were significantly lower by PRRSV while WBC, PLT, percentage and absolute number of neutrophils, basophils and LUCs increased. Significantly lower percentages of lymphocytes and increased percentages and absolute numbers of neutrophils, eosinophils and basophils were caused by PCV2 presence. Significantly lower percentage of lymphocytes and MCV and increased RBC, Hb, percentage and number of basophils and percentage of neutrophils were caused by HEV. Conclusions Alterations of haematological parameters reflected the health status of pigs of different categories on infected and on non-infected farms. Age-related changes in haematological parameters occurred in clinically healthy and in infected pigs.

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Values of Selected Haematological Indicators in Six Species of Feathered Game

Acta Veterinaria Brno ◽

10.2754/avb201079s9s003 ◽

2010 ◽

Vol 79 (9) ◽

pp. S3-S8 ◽

Cited By ~ 4

Author(s):

Eva Straková ◽

Pavel Suchý ◽

Romana Kábelová ◽

František Vitula ◽

Ivan Herzig

Keyword(s):

Blood Cell ◽

Total Concentration ◽

Haemoglobin Concentration ◽

Individual Species ◽

Neutrophil Granulocytes ◽

Corpuscular Haemoglobin ◽

Mean Corpuscular Haemoglobin Concentration ◽

Mean Corpuscular Haemoglobin ◽

The Mean ◽

Corpuscular Haemoglobin Concentration

The present paper extends the knowledge of selected blood indicators in six species of feathered game such as helmeted guineafowl (Numida meleagris), common pheasant (Phasianus colchicus), Japanese quail (Coturnix coturnix japonica), chukar (Alectoris chucar), grey partridge (Perdix perdix) and wild turkey (Meleagris gallopavo), reared in the Czech Republic and Europe. The red blood cell (RBC) values in individual species of feathered game ranged as follows: the mean RBC counts varied in a range of 2.10 - 2.58 T/l; haematocrit values were in a range of 0.33 - 0.39 1/1; haemoglobin concentration varied in a range of 101.20 - 129.13 g/l; mean corpuscular haemoglobin concentration (MCHC) ranged from 28.63 to 35.44%; mean corpuscular haemoglobin (MCH) varied in a range of 46.15 - 62.07 pg and the mean corpuscular volume (MCV) was 147.66 - 178.20 fl. Except for the total concentration of haemoglobin and the mean corpuscular haemoglobin concentration, no significant differences were found between the mean values of RBC values in individual species of feathered game. However, some differences between species were found in white blood cell (WBC) values, ranging as follows: the total WBC count ranged from 13.55 to 26.90 G/l, basophil granulocytes from 0.011 to 0.110 G/l, eosinophil granulocytes from 0.011 to 0.593 G/l, neutrophil granulocytes from 1.868 to 6.661 G/l, lymphocytes from 10.937 to 20.922 G/l and monocytes from 0.034 to 0.199 G/l. Most values showed significant (P ⪬ 0.05) to highly significant (P ⪬ 0.01) interspecies differences. The main goal of the study was to investigate selected haematological indicators in six major species of feathered game.

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Hematological Changes in Dogs Affected with Canine Babesiosis

THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY ◽

10.21887/ijvsbt.v12i3.7080 ◽

2017 ◽

Vol 12 (3) ◽

Author(s):

A. K. Bilwal ◽

G. C. Mandali ◽

A. C. Patel

Keyword(s):

Blood Cell ◽

Haemoglobin Concentration ◽

Canine Babesiosis ◽

Corpuscular Haemoglobin ◽

Microcytic Hypochromic Anaemia ◽

Hypochromic Anaemia ◽

Mean Corpuscular Haemoglobin ◽

Wbc Count ◽

Hematological Changes ◽

Hematological Evaluation

Canine babesiosis caused by tick-borne organisms of the genus Babesia, is one of the most significant disease worldwide. The aim of this study was to determine the haematological changes in dogs naturally infected with Babesia. The hematological evaluation included haemoglobin (Hb), red blood cell (RBC) count, platelets, white blood cell (WBC) count, differential leucocyte count (DLC), packet cell volume (PCV), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC). The haematological findings in most of these dogs revealed microcytic hypochromic anaemia, lowered platelet count and 75% cases had 24% decreased PCV. The results of the study showed that Babesia infection in dogs caused anaemia and thrombocytopenia.

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Sexual Dimorphism on Haematological and Genetic Parameters of Japanese Quails

Asian Journal of Advances in Agricultural Research ◽

10.9734/ajaar/2020/v12i430087 ◽

2020 ◽

pp. 1-11

Author(s):

J. E. Udoh ◽

U. H. Udoh ◽

A. A. Adeoye

Keyword(s):

Body Weight ◽

Blood Cell ◽

Management Practices ◽

Haemoglobin Concentration ◽

Haematological Parameters ◽

Mean Values ◽

Corpuscular Haemoglobin ◽

Japanese Quails ◽

Mean Corpuscular Haemoglobin ◽

The University

The study evaluated effect of Sex on Haematological parameters and Correlation with body weight of Japanese quails at Teaching and Research Farm of University of Uyo, Uyo, Nigeria. Authors declared that “principle of laboratory animal care” (NIH publication 85-23 revised 1985) were followed as well as the University law. The experiment has been examined and approved by the University law. Total of 400 birds (200 birds per sex) were reared in a Completely Randomized Design under standard management practices for 7 weeks with feed and water given ad libitum. Sex were considered treatments. Weekly body weight (BW) was measured. 100 birds per sex were randomly selected and blood samples were collected for haematological analysis. The parameters include: White Blood Cell(WBC), Red Blood Cell(RBC), Haemoglobin(Hb), Packed Cell Volume(PCV), Mean Corpuscular Volume(MCV), Mean Corpuscular Haemoglobin(MCH), Mean Corpuscular Haemoglobin Concentration(MCHC) and Platelet. The results showed that sex significantly (P< .05) influenced some of the haematological parameters of Japanese quails at 7 weeks. Females had significantly (P<.05) higher mean values in WBC (45.9 ±1.47 ×109/L), Hb (15.58±0.23 g/l) and PCV (47.75±0.72%) than males with WBC (32.09±1.31×109/L), Hb (13.72±0.25 g/l) and PCV (41.50±0.66%). There were no significant (P >.05) difference in mean values for RBC, MCV, MCH, MCHC and Platelet in both sexes measured. Correlation between BW and haematological parameters for male quails ranged from -10% to 50% (low to medium trend) while that of Female counterparts was -19% to 60% (low to high trend). In conclusion, female quails had higher values in WBC, Hb and PVC than the Males counterparts. Hence, female quails were considered fit for studying quails’ health status as this will help in establishing a breeding program of the quails than using Males. Body weight of female quails is a good selection tool to predict haematological parameters of quails.

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Haematology of N’Dama and West African Shorthorn cattle herds under natural Trypanosoma vivax challenge in Ghana

F1000Research ◽

10.12688/f1000research.14032.2 ◽

2018 ◽

Vol 7 ◽

pp. 314

Author(s):

Ebenezer Yaw Ganyo ◽

Johnson N Boampong ◽

Daniel K Masiga ◽

Jandouwe Villinger ◽

Paa Kobina Turkson

Keyword(s):

Blood Cell ◽

Control Measure ◽

Haemoglobin Concentration ◽

West African ◽

Haematological Parameters ◽

Northern Ghana ◽

Trypanosoma Vivax ◽

Corpuscular Haemoglobin ◽

Normal Ranges ◽

Mean Corpuscular Haemoglobin

Background: Animal trypanosomosis is a major cause of economic loss in livestock production in Africa. A suggested control measure is to use breeds with traits of trypanotolerance. The study examines the effect of natural Trypanosoma vivax challenge on haematological parameters in two trypanotolerant cattle [N’Dama and West African Shorthorn (WASH)] herds. Methods: Trypanosoma vivax-specific primers were used to diagnose T. vivax infection in an N’Dama herd at Cape Coast in southern Ghana and a WASH herd at Chegbani in northern Ghana from May to July 2011 in a cross-sectional study. Levels of haematological parameters comprising packed cell volume (PCV), haemoglobin (Hb) concentration and red blood cell (RBC) and total white blood cell (TWBC) counts; differential WBC counts (neutrophils, lymphocytes, eosinophils, monocytes and basophils); and RBC indices of mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) were determined in blood samples and then compared between infected and uninfected cattle. Results: We found that haematological indices for infected and uninfected animals in both breeds were within the normal range. However, the mean PCV values for T. vivax-infected WASH and N’Dama were lower in infected compared to uninfected animals. The difference was significant ( p< 0.05) in N’Dama but not in WASH. Conclusion: Despite the presence of infection by T. vivax, N’Dama and WASH cattle maintained their haematological parameters within acceptable normal ranges, which confirms their trypanotolerant trait. This highlights the need for low-input traditional African farmers in medium, high and severe tsetse challenge areas to be educated on the advantages of N’Dama and WASH breeds to increase their utilization in integrated tsetse and trypanosomosis control programmes.

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Haematological Profile Of Thai And Indigenous Male And Female Air Breathing Climbing Perch

Dhaka University Journal of Biological Sciences ◽

10.3329/dujbs.v21i1.9746 ◽

1970 ◽

Vol 21 (1) ◽

pp. 67-78

Author(s):

Mahmud Hasan ◽

Abdullah Al-Mamun ◽

Md Golam Rabbane

Keyword(s):

Haemoglobin Concentration ◽

Blood Parameters ◽

Haematological Parameters ◽

Male And Female ◽

Air Breathing ◽

Corpuscular Haemoglobin ◽

Climbing Perch ◽

Haematological Profile ◽

Mean Corpuscular Haemoglobin ◽

Hb Concentration

This study evaluated the haematological profile of air breathing Thai and indigenous male and female climbing perch (in Bangla, koi) Anabus testudineus to improve understanding the differences between two strains at blood parameters level. Haemoglobin (Hb), haematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), erythrocyte red blood cells (RBC) or erythrocytes, lymphocytes, monocytes, neutrophils and eosinophils were identified by mythic 18 automated haematology analyzer. Most haematological parameters indicated significant (p < 0.05) intra species sex variations. Higher Hb concentration, RBC counts and HCT percentages were found in Thai and indigenous males compared to their counterparts but higher MCH values, WBC counts and ESR levels were detected in both Thai and indigenous females than in the males. Similar concentration of Hb was detected in the same sex between fish. In contrast, higher level of ESR was observed in both female than did the males. Total counts of RBC observed in both Thai and indigenous male was significantly higher than in the females. MCV was found higher in indigenous male and female than in Thai one. However, no significant differences were observed in neutrophils, lymphocytes and eosinophils. Findings of this study showed sex variations in the haematological parameters between Thai and indigenous climbing perch. DOI: http://dx.doi.org/10.3329/dujbs.v21i1.9746 DUJBS 2012 21(1): 67-77

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Breed-Specific Haematologic Reference Values in Adult Turkeys (Meleagris gallopavo) in the Humid Tropics of Nigeria

Folia Veterinaria ◽

10.1515/fv-2017-0002 ◽

2017 ◽

Vol 61 (1) ◽

pp. 11-14

Author(s):

G. Daniel-Igwe ◽

N. Okwara

Keyword(s):

Blood Cell ◽

Reference Values ◽

Haemoglobin Concentration ◽

Meleagris Gallopavo ◽

Humid Tropics ◽

Haematological Parameters ◽

Mean Values ◽

Corpuscular Haemoglobin ◽

Standard Procedures ◽

Mean Corpuscular Haemoglobin

Abstract One hundred (50 males and 50 females) B-not strain indigenous turkeys, Meleagris gallopavo, were used to determine the reference values for their haematological parameters. The turkeys were housed in the poultry unit and jugular venepunctures were used to collect their blood. The haematological parameters were determined using standard procedures. The mean values of: the packed cell volume (PCV; 37.29 ± 0.37 %), red blood cell (RBC) counts (2.50 ± 0.44 × 106.µl−1), haemoglobin concentration (Hbc; 10.89 ± 0.34 g.dl−1), mean corpuscular volume (MCV; 150.63 ± 0.73 fl), mean corpuscular haemoglobin (MCH; 44.29 ± 1.78 pg), mean corpuscular haemoglobin concentration (MCHC; 29.10 ± 0.73 g.dl−1), and white blood cell (WBC) counts (12.41 ± 0.83 × 103 µl−1) were determined. No significant differences were found between the male and female B-not strain turkeys in this study. The results will help in the interpretation of cases of disease when there are variations in the values and serve as baseline data for B-not strain of turkeys in the humid tropics.

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Effects of Aqueous Root Bark Extracts of Anogeissus leiocarpus (DC) Guill & Perr and Terminalia avicennioides Guill & Perr on Redox and Haematological Parameters of Diethylnitrosamine-Administered Rats

Iranian Jornal of Toxicology ◽

10.32598/ijt.10.1.298.1 ◽

2016 ◽

Vol 10 (1) ◽

pp. 21-29

Author(s):

Amadu Kayode Salau ◽

◽

Musa Toyin Yakubu ◽

Adenike Temidayo Oladiji ◽

◽

...

Keyword(s):

Body Weight ◽

Blood Cell ◽

Cell Count ◽

Haemoglobin Concentration ◽

Haematological Parameters ◽

Root Bark ◽

Blood Cell Count ◽

Corpuscular Haemoglobin ◽

Mean Corpuscular Haemoglobin ◽

Anogeissus Leiocarpus

Background: This study investigated the protective effects of aqueous extracts of Anogeissus leiocarpus (DC) Guill & Perr (Combretaceae) and Terminalia avicennioides Guill & Perr (Combretaceae) root barks, as well as their 1:1 (w/w) mixture on liver redox and haematological parameters of diethylnitrosamine-treated rats. Methods: Rats were orally administered distilled water, diethylnitrosamine (30 mg/kg body weight once a week on weeks 3 and 4), curcumin (200 mg/kg body weight), extracts and 1:1 mixture (200, 400 and 800 mg/kg body weight) for 4 weeks. Malondialdehyde, markers of oxidative stress and hematological indices were evaluated. Results: The extracts and their mixture significantly (P<0.05) reversed the diethylnitrosamine-induced alterations in the levels of liver malondialdehyde, superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glucose 6-phosphate dehydrogenase, glutathione, vitamin C and platelet counts. The other haematological parameters (red blood cell count, haemoglobin concentration, packed cell volume, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, white blood cell count, lymphocyte count and neutrophil count) were not affected by diethylnitrosamine and extracts. Conclusion: The extracts possess antioxidant, hepatoprotective and haemoprotective activities that compared well with curcumin. These activities were better exhibited by the mixture than the individual extracts.

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Effects of Thyroid Function on Blood Cell Counts and Red Cell Indices – A Retrospective Study at a Tertiary Care Centre in Mandya, Karnataka

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2021/451 ◽

2021 ◽

Vol 8 (27) ◽

pp. 2434-2438

Author(s):

Siddegowda M.S ◽

Chaithra R ◽

Shivakumar S ◽

Maithri C.M

Keyword(s):

Blood Cell ◽

Blood Cells ◽

Thyroid Dysfunction ◽

Haematological Parameters ◽

Red Cell ◽

Corpuscular Haemoglobin ◽

Significant Difference ◽

Red Cell Indices ◽

Mean Corpuscular Haemoglobin ◽

Rbc Count

BACKGROUND Thyroid hormones play an important role in the regulation and production of red blood cells. Thyroid dysfunction induces different effects on blood cells such as anaemia, erythrocytosis, leucopenia, thrombocytopenia and alteration in red cell indices. In this study, we wanted to compare the changes in haematological parameters of thyroid dysfunction patients with those of euthyroid group. METHODS This was a retrospective study done on 310 individuals by collecting data from the medical records. Later the patients were categorized into hypothyroid (33) thyroid stimulating hormone (TSH > 5.5 μIU/mL), hyperthyroid (19) (TSH < 0.3 μIU/mL) and euthyroid (258) (TSH = 0.3 - 5.5 μIU/ml) groups. The haematological parameters of all these patients were obtained by 5-part automated cell count analyser. Finally, the obtained data was analyzed by statistical package for social sciences (SPSS) software. RESULTS The data obtained from the analysis revealed statistically significant (P < 0.05) difference between hypothyroidism, hyperthyroidism and euthyroidism in mean red blood cell (RBC) count, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), red cell distribution width (RDW), white blood cell (WBC) count and platelet count but the difference was not significant for mean haemoglobin, mean corpuscular haemoglobin concentration (MCHC) (P > 0.05). The mean haemoglobin was lower in hypothyroid patients when compared to euthyroid and hyperthyroid patients. The RBC count (P < 0.007), MCH (P = 0.002) and RDW (P < 0.001) showed statistically significant difference between hypothyroidism and euthyroidism, MCV (P = 0.005) showed statistically significant difference between hyperthyroid and euthyroid groups. CONCLUSIONS In case of patients with abnormal haematological parameters, thyroid hormones evaluation is necessary. KEYWORDS Hypothyroidism, Hyperthyroidism, Haemoglobin, Blood Count, Red Cell Indices

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