scholarly journals Early detection of subclinical dysfunction of left ventricle in dialysis patients.

2015 ◽  
Vol 10 (3-4) ◽  
pp. 64-64
Author(s):  
Slavica Mitrovska
2016 ◽  
Vol 39 (4) ◽  
pp. 111 ◽  
Author(s):  
Nuran Cetın ◽  
Nadide M Sav ◽  
Duran Karabel ◽  
Ali Yildirim ◽  
Bilal Yıldız

Purpose: Cardiovascular diseases are the main causes of morbidity and mortality in children with end-stage renal disease and the relationships among several relevant potential biomarkers were investigated in pediatric peritoneal dialysis patients. Methods: Serum homocysteine, von Willebrand factor (vWF), apolipoproteins A and B, lipoprotein-a, high sensitive-CRP, hemoglobin, phosphorus and parathyroid hormone (PTH) levels, systolic (SBP) and diastolic (DBP) blood pressure, carotid intima-media thickness (cIMT) and left ventricular mass index (LVMI) were measured in 21 pediatric peritoneal dialysis patients and control subjects. Results: All risk factors were higher in patients than controls. LVMI values were negatively correlated with hemoglobin and positively correlated with PTH and phosphorus levels (p=0.007, r= - 0.573; p=0.013, r= 0.532 and p=0.035, r= 0.461, respectively). cIMT was negatively associated with serum albumin and positively correlated with vWF levels and with SBP and DBP (p=0.006, r= - 0.578; p=0.039, r= 0.453; p=0.02, r= 0.503; p=0.024, r= 0.491, respectively). Robust regression analyses showed that hemoglobin was an independent predictor of LVMI and serum albumin was an independent predictor of cIMT. Conclusion: Only uremia-related factors were independent risk factors for predicting LVMI and cIMT. Hemoglobin level may be a critical factor in the development of left ventricular hypertrophy; therefore, effective treatment of anemia is crucial. Low serum albumin and high hsCRP and vWF levels, and their correlations with cIMT, indicate these patients could be at risk of developing malnutrition–inflammation–atherosclerosis syndrome and suggest that serum albumin and vWF levels may be useful markers for early detection of vascular damage.


Radiology ◽  
2014 ◽  
Vol 271 (2) ◽  
pp. 373-380 ◽  
Author(s):  
Franck Thuny ◽  
Daniel Lovric ◽  
Frédéric Schnell ◽  
Cyrille Bergerot ◽  
Laura Ernande ◽  
...  

EP Europace ◽  
2016 ◽  
Vol 18 (suppl_1) ◽  
pp. i113-i113
Author(s):  
Mohammad Hosein Nikoo ◽  
Alireza Moaref ◽  
Arash Yazdanshenas ◽  
Sara Ramezanpour ◽  
Pouya Farhadi

2012 ◽  
Vol 7 (1) ◽  
pp. 39-41
Author(s):  
Nilufar Fatema ◽  
Ahmed Saiful Bari ◽  
Naznin Sultana ◽  
Mohammad Al Mamun ◽  
SM Mustafa Sultan ◽  
...  

Ventricular noncompaction is a kind of cardiomyopathy which is called Noncompaction Cardiomyopathy (NCC). In this condition in which the muscular wall of the main pumping chamber of the heart -the left ventricle (LV) appears to be spongy and “non-compacted”, consisting of a meshwork of numerous muscle bands called trabeculations. Here, anatomically LV wall has deep trabeculations. This condition is associated major clinical problems like systolic and diastolic dysfunction, arrhythmia and even systemic embolism. Sudden cardiac death may occur in this group. Early detection of this condition may help to plan the management. DOI: http://dx.doi.org/10.3329/uhj.v7i1.10209 UHJ 2011; 7(1): 39-41


2021 ◽  
Vol 12 (1) ◽  
pp. 5-10
Author(s):  
Olesia V. Gritsenko ◽  
Galina A. Chumakova ◽  
Elena V. Trubina

Despite the undoubted success in the diagnosis of heart failure using echocardiography, the issue of detecting diastolic dysfunction of the left ventricle of the heart in the early stages remains insufficiently studied. The article describes a non-invasive ultrasound method for evaluating myocardial function, which allows early detection of left ventricle diastolic dysfunction due to myocardial fibrosis.


2021 ◽  
Vol 9 (1) ◽  
pp. 116
Author(s):  
Parth K. Thakkar ◽  
Mahesh Bhatt ◽  
Sheela Bharani Chawla ◽  
Hitesh Desai

Non-compaction of left ventricular (NCLV) is a rare cardiomyopathy of unknown origin characterized by prominent ventricular trabeculations and deep intertrabecular sinusoids, in communication with the left ventricular cavity. The NCLV results due to failure of compaction during foetal development. In this study, five children were diagnosed with NCLV out of 135 cases of cardiomyopathy and the youngest case was diagnosed at 27th day of life. Congestive cardiac failure presenting as tachycardia and tachypnea were common clinical manifestations. Early detection of NCLV helps patients to get timely treatment. NCLV should be considered as one of the differential diagnosis amongst cases of cardiomyopathy.


2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Joachim Harlos ◽  
Andreas Maierhofer ◽  
Bernard Canaud

Abstract Background and Aims Hyponatremia in dialysis patients is a strong indicator of poor outcome in dialysis patients that requires early detection to facilitate clinical workup and management. However, plasma sodium concentration as determined by lab methods (Na-Lab) is measured at the best monthly in clinical practice. Recently, online monitoring of predialytic plasma Na (pPlNa) as estimated from dialysate conductivity using an electrolyte model has become available at every hemodialysis session, thus providing an unprecedented close and almost continuous monitoring of this crucial indicator. This could be used as diagnostic tool to identify changes in patient status and alert earlier the physician. Method In a monocentric retrospective clinical study in 114 patients on maintenance hemodialysis (>90% online postdilution HDF) for whom online pPlNa was available for a period of at least 12 months at least once a week, kinetics of pPlNa were analyzed. For 10 patients with hyponatremic episodes as manifested in pPlNa, the agreement between time course of pPlNa and Na-Lab and the correlation to the manifestation of clinical findings was explored. Results Time course of pPlNa and Na-Lab showed very good agreement. Hyponatremia onset was clinically related to diagnoses such as fluid overload and congestive heart failure, diarrhea secondary to inflammatory bowel disease, sepsis, liver cirrhosis, cancer and use of loop diuretics. Conclusion The clinical examples show that due to the good agreement of the time course of online monitoring of pPlNa and Na-Lab, pPlNa can be used as adjuvant diagnostic tool for the early detection of onset and progression of morbid events. Due to its routine availability variations in pPlNa could be used to timely trigger clinical workup and investigations.


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