scholarly journals Vitamin D Serum Level in Patients with Schizophrenia in West Java, Indonesia

2020 ◽  
pp. 122-127
Author(s):  
Nofan Pratama Maulana ◽  
Tuti Kurnianingsih ◽  
Sumartini Dewi
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Vitamin D Deficiency ◽  
Mental Hospital ◽  
Serum Vitamin ◽  
Vitamin D Insufficiency ◽  
West Java ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Schizophrenic Patients

Background: Vitamin D is an immune-regulator that influences the neuro-inflammation process in schizophrenia. The study aimed to explore the vitamin D serum level in schizophrenic patients at the outpatient clinic of the Provincial Mental Hospital, West Java, Indonesia. Methods: A quantitative descriptive study was conducted in November-December 2019 using secondary data of all-male schizophrenic patients at the Provincial Mental Hospital. Data collected were demographic characteristics, clinical characteristics, and vitamin D Level. Scoring was then performed using Positive and Negative Syndrome Scale (PANSS) and Montreal Cognitive Assessment (MoCA) to assess the positive and negative symptoms as well as the cognitive symptoms based on the serum vitamin D levels. Result: All male schizophrenic patients had a low serum vitamin D level (mean16.67±5.6ng/ml) with 64.52% of them had vitamin D deficiency (<20 ng/ml). Interestingly, patients with vitamin D deficiency had a negative symptom (mean22.1±5.6ng/ml) whereas those with vitamin D insufficiency (20-29 ng/ml) had a positive symptom (mean 18.55±5.6ng/ml). Furthermore, patients with vitamin D deficiency had a lower impaired cognitive function value (mean 19.7±3.4ng/ml) compared to those with vitamin D insufficiency. Conclusions: A low vitamin D serum level in schizophrenic patients may play a role in the pathogenesis of this disorder. Further studies are needed to confirm this finding.

scholarly journals Prevalence and Treatment of Vitamin D Deficiency in Young Male Russian Soccer Players in Winter

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2405 ◽  
Author(s):  
Bezuglov ◽  
Tikhonova ◽  
Zueva ◽  
Khaitin ◽  
Waśkiewicz ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Young Male ◽  
Vitamin D Insufficiency ◽  
Soccer Players ◽  
Football Players ◽  
Duration Of Treatment ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Vitamin D (25(OH)D) insufficiency and deficiency are highly prevalent in adult soccer players and can exceed 80% even in regions with high insolation; however, the treatment of this condition is often complicated. The aim of the present study was to examine the prevalence of vitamin D insufficiency and deficiency in youth Russian soccer players and the efficacy of its treatment. Participants were 131 young male football players (age 15.6 ± 2.4 years). Low vitamin D levels (below 30 ng/mL) were observed in 42.8% of the analyzed participants. These athletes were split in two groups composed of persons with vitamin D deficiency (serum vitamin D below 21 ng/mL) and insufficiency (serum vitamin D in range of 21–29 ng/mL). A dietary supplement of 5000 IU cholecalciferol per day was administered for two months. After the treatment, an average 92% increase in vitamin D concentration was observed (before treatment—19.7 ± 5.4 ng/mL, after treatment—34.7 ± 8.6 ng/mL, p<0.001) and 74% of the post-treatment values were within the reference range (30–60 ng/mL). Serum concentration of vitamin D increased by 200% ± 98% (p<0.001) during the first month of treatment with vitamin D deficiency and insufficiency being successfully treated in 83% of the football players. In summary, the prevalence of vitamin D insufficiency and deficiency was high in young Russian soccer players. Furthermore, it was indicated that the daily usage of cholecalciferol in a dose 5000 IU was an effective and well-tolerated treatment for vitamin D insufficiency. No linear dependency between the duration of treatment and increase in vitamin 25(OH)D concentration was observed.

scholarly journals Assessment of Relationship Between Serum Vitamin D Levels and Metabolic Syndrome Components in Hemodialysis Patients

2021 ◽  
Vol 28 (1) ◽  
pp. E202113
Author(s):  
Sevil Karahan Yılmaz ◽  
Cuma Mertoğlu ◽  
Aylin Ayaz
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Vitamin D Insufficiency ◽  
Hemodialysis Patients ◽  
Hydroxyvitamin D ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D

Aim: This study is aimed to evaluate the relationship between serum vitamin D levels and metabolic syndrome in hemodialysis patients. Materials and Methods: This study was conducted with participation of 80 patients undergoing hemodialysis for more than 6 months three times a week, aged > 18 years. Their height, dry weight, waist circumference were measured. Biochemical parameters such as serum 25-hydroxyvitamin D, lipid profile, and fasting blood glucose were analyzed. Metabolic syndrome was defined using the National Cholesterol Education Program Adult Treatment Panel III criteria. Severe vitamin D deficiency, 25 (OH) vitamin D < 5 ng/ml; mild vitamin D deficiency, 25 (OH) vitamin D 5-15 ng/ml; vitamin D insufficiency, 25 (OH) vitamin D 16-30 ng/ml, and vitamin D sufficiency, 25 (OH) vitamin D > 30 ng/ml were categorized. Statistical analysis of the data was performed with the use of SPSS version 21.0. Results: 48.4% of hemodialysis patients were identified to have metabolic syndrome. According to the serum levels of vitamin D; 35.0% of patients had severe vitamin D deficiency, 37.4% of patients had mild vitamin D deficiency, 18.8% of patients had vitamin D insufficiency and 8.8% of patients had vitamin D sufficiency (> 30 ng/ml). Vitamin D insufficiency was significantly associated with metabolic syndrome and central obesity. Conclusions: Deficiency/insufficiency is observed in serum 25-hydroxyvitamin D levels in hemodialysis patients. Vitamin D insufficiency is associated with metabolic syndrome.

scholarly journals Seric status of vitamin D among nulligest women at the general reference hospital of Panzi in Democratic Republic of the Congo

2021 ◽  
Vol 10 (5) ◽  
pp. 1963
Author(s):  
Sifa Balungwe ◽  
Raha Maroyi ◽  
Mpakanyi Joyeux ◽  
Mukango Omari ◽  
Mulongo Philémon ◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Vitamin D Deficiency ◽  
Pelvic Pain ◽  
Democratic Republic ◽  
Serum Vitamin ◽  
General Reference ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Reference Hospital

Background: Vitamin D has both bony and extra bony implications. The objective of this study was to determine serum vitamin D levels in non-breastfeeding women aged 20 to 35 years.Methods: A cross-sectional study was conducted at the Panzi General Reference Hospital in the Democratic Republic of Congo (DRC) with an occasional sample of 412 nulligest women sensitized during gynecological consultations. A vitamin D test was performed using the immunofluorescence technique and a trans-abdominal ultrasound was routinely performed. Vitamin D deficiency was defined by a serum level ≤29 ng/dl. Data were collected using a pre-established survey questionnaire.Results: The mean age of the women was 25.23±4.54 years. The serum vitamin D level was 77.2% too high, indicating vitamin D deficiency in our context. The nulliparous, students and overweight women were the most encountered. Women who consumed more red meat, green vegetables and alcohol were more affected. Pelvic pain, pelvic pain and bleeding between periods dominated the clinical picture.Conclusions: The serum level was very high in nulligest women aged 20 to 35 years. The study recommends expanded screening and vitamin D supplementation for the prevention of myomas and other conditions in nulligest women.  

High Prevalence of Vitamin D Deficiency and Associated Risk Factors among Employed Women in a Sunny Industrial City

2015 ◽  
Vol 85 (3-4) ◽  
pp. 119-128 ◽  
Author(s):  
Tahereh Hassannia ◽  
Ehsan GhaznaviRad ◽  
Rosita Vakili ◽  
Sohaila Taheri ◽  
Seyed Abdolrahim Rezaee
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Serum Level ◽  
Vitamin D Deficiency ◽  
Muscle Pain ◽  
Serum Vitamin ◽  
Industrial City ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Employed Women

Abstract. Background: Vitamin D deficiency is a public health concern associated with the pathogenesis of several chronic disorders, particularly in women. Aim: To evaluate serum vitamin D levels and its deficiency and risk factors among employed women in a sunny industrial city. Methods: In this cross-sectional study, serum vitamin D levels, biochemical and hematological factors were assessed in 382 healthy employed women. Demographic information was collected using a standard questionnaire and data was analyzed by SPSS software. Results: The mean vitamin D serum level was 22 ± 19.8 ng/ml. Prevalence of vitamin D deficiency and insufficiency were 62 % and 12.94 %, respectively. Deficiency was more common among younger subjects (< 29 years old). 23.5 % of subjects had normal and 1.35 % had toxic levels of vitamin D. Maximum serum level was observed in part-time job employees (33 ng/ml), and the lowest in Media and Culture Organizations (15 ng/ml).Vitamin D deficiency was associated with the lack of sunlight exposure at home, and taking anti-hypertensive medications. The common symptoms in deficiency condition were history of hyperlipidemia, depression, weakness, fatigue, finger tingling, leg cramps, and body and muscle pain. Moreover, LDL-cholesterol serum levels were significantly higher in the vitamin D deficiency group, with a prevalence of 40 %. Conclusion: The symptoms of vitamin D deficiency including depression, weakness, fatigue, tingling, leg cramps and body and muscle pain have been observed in more than 90 % after recruitment and treatment. Therefore, for improving the health and productivity of employees, a routine monitoring system for vitamin D and the other factors should be put in place.

scholarly journals Association Between Low Serum Vitamin D Levels and Sepsis: A Single-Center Study in Tehran, Iran

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Masume Bayat ◽  
Latif Gachkar ◽  
Mahya Zahirnia ◽  
Fahimeh Hadavand
Keyword(s):  
Vitamin D ◽  
Severe Sepsis ◽  
Vitamin D Deficiency ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Plasma Concentrations ◽  
Serum Vitamin ◽  
Vitamin D Insufficiency ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Background: Vitamin D insufficiency is common in critically ill patients. It is hypothesized that vitamin D deficiency would be associated with sepsis in the critically ill. Thus, the present study aimed to investigate the association between vitamin D and sepsis severity. Method: In this cross-sectional study, patients with sepsis referring to a university hospital in Tehran, Iran, from February 2018 to March 2019 were included. Plasma concentrations of vitamin D in critically ill subjects admitted were assessed. Data were analyzed using SPSS version 20.0. P-values less than 0.05 were considered statistically significant. Results: Among the investigated patients, the mean serum level of vitamin D3 was 19.03 ± 13.08 ng/mL. The prevalence of vitamin D insufficiency in critically ill subjects with sepsis was 100% (150/150). Only sex (P = 0.01) indicated a significant association with vitamin D. Patients suffering from severe sepsis had lower levels of vitamin D compared to the patients with non-severe sepsis (P = 0.07). Conclusions: The present study showed that all critically ill patients studied had vitamin D insufficiency. In line with the biological evidence, the present study suggests that vitamin D deficiency may predispose patients to sepsis. Further studies are needed to establish the causes and mechanisms underlying these interpretations.

scholarly journals Relationships between low serum vitamin D levels and HBV “a” determinant mutations in chronic hepatitis B patients

2016 ◽  
Vol 10 (09) ◽  
pp. 1025-1030 ◽  
Author(s):  
Huijuan Zhu ◽  
Xingxiang Liu ◽  
Yi Ding ◽  
Hui Zhou ◽  
Yiying Wang ◽  
...  
Keyword(s):  
Vitamin D ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Vitamin D Deficiency ◽  
Chronic Hepatitis B ◽  
Serum Vitamin ◽  
Vitamin D Insufficiency ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Low Serum

Introduction: Vitamin D is significantly associated with virus replication in chronic hepatitis B virus (HBV) infection. However, the relationship between low serum vitamin D levels and HBV “a” determinant mutations remains unknown. Methodology: A total of 133 chronically HBV-infected, treatment-naive patients were randomly selected in the present study. Serum vitamin D levels were measured by using liquid chromatography-mass spectrometry. The HBV “a” determinant was amplified, sequenced, and analyzed by nested polymerase chain reaction (PCR). Results: Among 133 patients, 36, 88, and 9 patients had vitamin D deficiency (25(OH)D < 14 ng/mL), vitamin D insufficiency (25(OH)D ≥ 14 and < 30 ng/mL), and normal vitamin D serum levels ((25(OH)D ≥ 30 ng/mL), respectively. As results showed, 36 [11 genotype B HBVs (HBV/B) and 25 genotype C HBVs (HBV/C)] were isolated from the vitamin D-deficient group, 88 (48 HBV/B and 40 HBV/C) from the vitamin D-insufficient group, and 4 HBV/C strains from the normal serum-vitamin D group. Compared to the HBV/B infected patients with vitamin D insufficiency, higher rates of amino acid mutation within “a” determinant were detected in HBV/B-infected, vitamin D-deficient patients. Moreover, the change frequency of M133 was 27.27% in HBV/B infected patients with vitamin D deficiency, which was significantly higher than those in the vitamin D-insufficient group (p = 0.040). Conclusions: Vitamin D deficiency is significantly associated with genotype B HBV “a” determinant mutations.

Vitamin D deficiency in minority populations

2014 ◽  
Vol 18 (3) ◽  
pp. 379-391 ◽  
Author(s):  
Glen B Taksler ◽  
David M Cutler ◽  
Edward Giovannucci ◽  
Nancy L Keating
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Sun Exposure ◽  
Vitamin D Insufficiency ◽  
Vitamin D Supplementation ◽  
Minority Populations ◽  
Uv Index ◽  
Serum Vitamin D ◽  
Vitamin D Levels

AbstractObjectiveBlack and Hispanic individuals synthesize less vitamin D per unit of sun exposure than white individuals. The relationship between UV radiation and vitamin D insufficiency in minorities has not been well explored.DesignProspective cohort study.SettingUsing the National Health and Nutrition Examination Survey, we obtained serum vitamin D levels for non-Hispanic Whites, Hispanics and non-Hispanic Blacks aged ≥18 years from 2000–2006. We linked these data with the average monthly solar UV index by census tract and data on sun exposure, vitamin D supplementation, health and demographics. We used multivariable regression analyses to assess vitamin D deficiency (<15 ng/ml) and insufficiency (<20 ng/ml) in January (when the UV index was lowest) by race/ethnicity and geography.SubjectsAdults (n 14 319) aged ≥18 years.ResultsA 1-point increase in the UV index was associated with a 0·51 ng/ml increase in vitamin D (95 % CI 0·35, 0·67 ng/ml; P<0·001). Non-Hispanic Black race and Hispanic ethnicity were associated with a 7·47 and 3·41 ng/ml decrease in vitamin D, respectively (both P<0·001). In January, an estimated 65·4 % of non-Hispanic Blacks were deficient in vitamin D, compared with 28·9 % of Hispanics and 14·0 % of non-Hispanic Whites. An estimated 84·2 % of non-Hispanic Blacks were insufficient in vitamin D v. 56·3 % of Hispanics and 34·8 % of non-Hispanic Whites. More non-Hispanic Blacks were estimated to be deficient in vitamin D in January in the highest UV index quartile than were non-Hispanic Whites in the lowest UV index quartile (60·2 % v. 25·7 %).ConclusionsWintertime vitamin D insufficiency is pervasive among minority populations, and not uncommon among non-Hispanic Whites.

scholarly journals Maternal Vitamin D Status and Risk of Preeclampsia in Abuja, Nigeria

2019 ◽  
pp. 1-10
Author(s):  
Kate Ifeoma Omonua ◽  
Olutunde Onafowokan ◽  
Nathaniel Adewole ◽  
Maxwell Nwegbu ◽  
Aliyu Yabaji Isah ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Vitamin D Insufficiency ◽  
Maternal Serum ◽  
Cross Sectional ◽  
Maternal Vitamin ◽  
Serum Vitamin D ◽  
Healthy Women ◽  
Vitamin D Levels

Aim: To determine the relationship between maternal serum 25(OH) D concentrations and development of preeclampsia. Study Design: A cross sectional comparative study. Place and Duration of Study: Department of Obstetrics and Gynaecology, University of Abuja Teaching Hospital, Abuja, between March 2016 and February 2017. Methodology: We included 55 women with preeclampsia and 55 healthy women. Data obtained included sociodemographic characteristics, clothing style and duration of exposure to sun light.  ELISA method was used for evaluation of serum vitamin D levels. Results: The prevalence of VD deficiency in the population was 15%, while 16.8% and 73% of the participants had insufficient and normal levels respectively. The prevalence of VD deficiency in women with preeclampsia was 20.4% while that in healthy pregnant women was 9.4% (P=.19). The mean serum 25-OH-D level of women with pre-eclampsia was significantly lower than that of healthy women (34.5±14.9 vs. 43.5±15.1, P = .003). Preeclamptic women with vitamin D insufficiency delivered at a higher gestational age than those with vitamin D deficiency (37.67(2.77) weeks vs. 33.55(2.38) weeks respectively, P = .007). In the adjusted analysis of cases with vitamin D defficiency, the odds of developing preeclampsia was not statistically significant [odds ratio (OR) = 3.27, CI = 0.99-10.83, P =.05].  However, the odds of developing preeclampsia in women with Vitamin D insufficiency was statistically  significant (OR = 3.20, CI = 1.02–10.06,  = 0.046). Conclusion: In conclusion, an association between vitamin D deficiency and preeclampsia was not demonstrated in this study. The results however suggest that maternal vitamin D insufficiency in late pregnancy is an independent risk factor for preeclampsia.

scholarly journals SCREENING FOR VITAMIN D, CALCIUM AND THYROID HORMONE SERUM LEVELS IN HEALTHY ADULT LIBYAN FEMALES

2020 ◽  
Vol 8 (12) ◽  
pp. 483-487
Author(s):  
Rehab R Walli ◽  
◽  
Amal A Ammar ◽  
Rema A Abojarida ◽  
◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
Thyroid Hormones ◽  
Vitamin D Deficiency ◽  
Healthy Adult ◽  
Serum Vitamin ◽  
Serum Levels ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
The Status

Vitamin D deficiency is becoming endemic in many parts of the world.Several studies demonstrated a relationship between vitamin D deficiency, hypocalcemia and thyroid disorders. The purpose of this study was to examine the serum level of Vitamin D in healthy adult Libyan women and the status ofserum calcium and thyroid hormones. Serum vitamin D levels were measured in 174 healthy women who are classified in groups according to the age(Mean age 34±14 years). Our results revealed that vitamin D deficiency is very common among Libyan adult females because the mean of vitamin D was 13.4 ± 6.4 (n=174). Vitamin D deficiency was considered at serum levels lower than 20 ng/ml.In addition, we evaluated serum level ofcalcium and Thyroidfunction hormones (TSH, T3 and T4) in only60participants from 174 who are included in this study.It has been previously shown that individuals with low vitamin D levels have low thyroid functionbut our results here indicated that serum thyroid hormones and calcium analysis were lay within the normal rang in most of the participants. Therefore, we strongly recommend the screening for Vitamin D deficiency in all adult Libyan females and encourage the advisability of increasing vitamin D intake combined with following up its serum level to avoid over dose.

scholarly journals Impact of vitamin D serum levels on clinicopathological features and outcome in advanced pancreatic carcinoma

2021 ◽  
Vol 12 (1) ◽  
pp. 22-30
Author(s):  
Amrallah A. Mohammed ◽  
Reham A. Salem
Keyword(s):  
Vitamin D ◽  
Pancreatic Carcinoma ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Vitamin D Insufficiency ◽  
Clinicopathological Features ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Advanced Pancreatic Carcinoma

Abstract Background Growing evidence encourages the preventive role of vitamin D in pancreatic carcinoma (PC). Meanwhile, the prognostic or predictive role needs more investigations. This study aimed to evaluate the correlation between serum vitamin D levels and the clinicopathological features with the outcome in advanced pancreatic carcinoma (APC). Materials and methods The current prospective study included 176 patients with APC. Assessing 25-hydroxy vitamin D is the most accurate method to measure the serum vitamin D levels. Serum vitamin D levels <20 ng/ml are defined as vitamin D deficiency, while levels ranging from 20 to 29 ng/ml are defined as vitamin D insufficiency. Before any treatment modalities were administered, the serum vitamin D levels were measured by enzyme-linked immunosorbent assay (ELISA). Results Serum vitamin D insufficiency and deficiency were detected in 28.4% and 31.8%, respectively. A large tumor size, higher grade, liver metastasis, higher serum level of CA 19-9, poor ECOG PS, and low overall response rate (ORR) were associated with lower serum vitamin D levels (p = 0.000). The median follow-up period was 7.6 months (range 0.6–18.6). The ORR was 23.2%, 54%, and 82.9% of vitamin D deficiency, insufficiency, and normal levels of vitamin D, respectively. The median OS was 11.4 months for patients with normal serum vitamin D levels, compared with 2.7 and 7.03 months for serum vitamin D deficiency and insufficiency, respectively. Conclusion Among patients with APC, serum vitamin D levels are considered a promising prognostic factor. It is associated with various poor prognostic features and worse survival outcome.

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