Pain in the bipolar disorder: prevalence, characteristics and relationship with suicide risk

Objective: to know the prevalence and characteristics of pain, to verify how pain management has been carried out by the health services, and to correlate suicide risk with pain intensity in patients with bipolar disorder. Method: an observational study with a quantitative approach. The study included people with bipolar disorder assessed by the McGill-Reduced Pain Questionnaire, Body Diagram, Visual Numerical Scale, and the Suicidal Ideation Scale (Beck). Results: the sample of 60 participants was mainly composed of women with a mean age of 40 years old and a mean psychiatric treatment time of approximately 13 years. Of these, 83% reported feeling pain at the time of the interview. Half of the participants indicated that pain interferes with routine and 80% did not receive care in health institutions. The main descriptors that qualify the painful experience were as follows: painful, heavy and sensitive for the sensory descriptors, tiring and punishing in the affective category. Suicide attempt was reported by 57% of the participants. There was a correlation between suicide risk and pain intensity. Conclusion: pain presented a high prevalence. Suicide risk was identified in more than half of the participants. Pain intensity showed a significant correlation with suicide risk.

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Psychological interventions to reduce suicidality in high-risk patients with major depression: a randomized controlled trial

Psychological Medicine ◽

10.1017/s0033291716002798 ◽

2016 ◽

Vol 47 (5) ◽

pp. 810-821 ◽

Cited By ~ 26

Author(s):

C. M. Celano ◽

E. E. Beale ◽

C. A. Mastromauro ◽

J. G. Stewart ◽

R. A. Millstein ◽

...

Keyword(s):

Suicidal Ideation ◽

Suicide Risk ◽

Psychiatric Treatment ◽

Controlled Trial ◽

Treatment Manual ◽

Post Discharge ◽

Psychological Constructs ◽

Control Intervention ◽

Psychiatric Units ◽

Positive Feelings

BackgroundPositive psychological constructs have been associated with reduced suicidal ideation, and interventions to cultivate positive feelings have the potential to reduce suicide risk. This study compares the efficacy of a 6-week, telephone-based positive psychology (PP) intervention against a cognition-focused (CF) control intervention among patients recently hospitalized for depression and suicidal ideation or behavior.MethodA total of 65 adults with a current major depressive episode reporting suicidal ideation or a recent suicide attempt were enrolled from participating in-patient psychiatric units. Prior to discharge, participants were randomized to the PP (n = 32) or CF (n = 33) intervention. In both interventions, participants received a treatment manual, performed weekly PP (e.g. gratitude letter) or CF (e.g. recalling daily events) exercises, and completed weekly one-on-one telephone sessions over 6 weeks. Between-group differences in hopelessness (primary outcome), depression, suicidality and positive psychological constructs at 6 and 12 weeks were tested using mixed-effects models accounting for intensity of post-hospitalization psychiatric treatment.ResultsCompared with PP, the CF intervention was associated with significantly greater improvements in hopelessness at 6 weeks (β = −3.15, 95% confidence interval −6.18 to −0.12, effect size = −0.84, p = 0.04), but not 12 weeks. Similarly, the CF intervention led to greater improvements in depression, suicidal ideation, optimism and gratitude at 6 and 12 weeks.ConclusionsContrary to our hypothesis, the CF intervention was superior to PP in improving hopelessness, other suicide risk factors and positive psychological constructs during a key post-discharge period among suicidal patients with depression. Further study of this CF intervention is warranted in populations at high suicide risk.

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Depression, anxiety symptoms and substance use amongst sex workers attending a non-governmental organisation in KwaZulu-Natal, South Africa

South African Family Practice ◽

10.4102/safp.v59i3.4538 ◽

2017 ◽

Vol 59 (3) ◽

pp. 55

Author(s):

Vinola Poliah ◽

Saeeda Paruk

Keyword(s):

Mental Health ◽

Substance Use ◽

Suicidal Ideation ◽

Sex Workers ◽

Mental Health Problems ◽

Psychiatric Treatment ◽

Psychiatric Symptoms ◽

Anxiety Symptoms ◽

High Prevalence ◽

Self Reporting Questionnaire

Background: Sex work is a high-risk occupation for mental health problems as sex workers are vulnerable to high rates of violence, sexual coercion, stigma and HIV. Aim: To determine the prevalence of depressive and anxiety symptoms and substance use in sex workers.Method: A crosssectional questionnaire survey of all men and women attending the Sisonke health initiative, a non-profit non-governmental organisation (NGO), for sex workers was conducted over three months. A socio-demographic questionnaire, the Self Reporting Questionnaire (SRQ 20), the Patient Health Questionnaire (PHQ 9) and the WHO Alcohol, Smoking and Substance Involvement Screening Test (ASSIST V3.0) were administered. Results: A total of 155 participants were surveyed. The prevalence of anxiety and depressive symptoms on the SRQ 20 and PHQ 9 total scores were 78.4% and 80.9% respectively. Some 40% of sex workers reported suicidal ideation in the year preceding the study. High rates of violence (n = 112, 72%) and childhood abuse (n = 107, 69%) were reported. The prevalence of HIV was 76.1%. The lifetime prevalence of substance use for nicotine (87.8%), alcohol (87.8%) and cannabis (87.7%) was high. Despite the high prevalence of psychiatric symptoms reported, only 15 (9.7%) participants were receiving psychiatric treatment at the time of the survey. Conclusions: The high prevalence of anxiety, depression, suicidal ideation, substance use and co-morbid HIV infection reported by sex workers and the significant treatment gap suggests an urgent need to provide an integrated health service that targets physical and mental health in sex workers. (Full text of the research articles are available online at www.medpharm.tandfonline.com/ojfp) S Afr Fam Pract 2017; DOI: 10.1080/20786190.2016.1272247

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Graph theory analysis of whole brain functional connectivity to assess disturbances associated with suicide attempts in bipolar disorder

Translational Psychiatry ◽

10.1038/s41398-021-01767-z ◽

2022 ◽

Vol 12 (1) ◽

Author(s):

Anjali Sankar ◽

Dustin Scheinost ◽

Danielle A. Goldman ◽

Rebecca Drachman ◽

Lejla Colic ◽

...

Keyword(s):

Bipolar Disorder ◽

Suicidal Ideation ◽

Functional Connectivity ◽

Suicide Risk ◽

Suicide Attempts ◽

Imaging Data ◽

Significant Group ◽

Whole Brain ◽

Graph Theoretical Approach ◽

Suicide Behaviors

AbstractBrain targets to lower the high risk of suicide in Bipolar Disorder (BD) are needed. Neuroimaging studies employing analyses dependent on regional assumptions could miss hubs of dysfunction critical to the pathophysiology of suicide behaviors and their prevention. This study applied intrinsic connectivity distribution (ICD), a whole brain graph‐theoretical approach, to identify hubs of functional connectivity (FC) disturbances associated with suicide attempts in BD. ICD, from functional magnetic resonance imaging data acquired while performing a task involving implicit emotion regulation processes important in BD and suicide behaviors, was compared across 40 adults with BD with prior suicide attempts (SAs), 49 with BD with no prior attempts (NSAs) and 51 healthy volunteers (HVs). Areas of significant group differences were used as seeds to identify regional FC differences and explore associations with suicide risk-related measures. ICD was significantly lower in SAs than in NSAs and HVs in bilateral ventromedial prefrontal cortex (vmPFC) and right anterior insula (RaIns). Seed connectivity revealed altered FC from vmPFC to bilateral anteromedial orbitofrontal cortex, left ventrolateral PFC (vlPFC) and cerebellum, and from RaIns to right vlPFC and temporopolar cortices. VmPFC and RaIns ICD were negatively associated with suicidal ideation severity, and vmPFC ICD with hopelessness and attempt lethality severity. The findings suggest that SAs with BD have vmPFC and RaIns hubs of dysfunction associated with altered FC to other ventral frontal, temporopolar and cerebellar cortices, and with suicidal ideation, hopelessness, and attempt lethality. These hubs may be targets for novel therapeutics to reduce suicide risk in BD.

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Epilepsy drugs do not appear to increase suicide risk in patients with bipolar disorder

PsycEXTRA Dataset ◽

10.1037/e667632010-003 ◽

2010 ◽

Keyword(s):

Bipolar Disorder ◽

Suicide Risk

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The experience of using a diode laser in the herpes labial treatment

Periodontology ◽

10.33925/1683-3759-2020-25-1-43-46 ◽

2020 ◽

Vol 25 (1) ◽

pp. 43-46

Author(s):

S. L. Blashkova ◽

E. V. Krikun ◽

Yu. V. Fazylova ◽

Yu. V. Blashkova

Keyword(s):

Oral Cavity ◽

Diode Laser ◽

Comparison Group ◽

Treatment Time ◽

Local Treatment ◽

Allergic Reactions ◽

High Prevalence ◽

Dental Diseases ◽

Simplex Virus

Relevance. The relevance of the problem is in the high prevalence of the herpes simplex virus. According to WHO, nearly 90% of the population are carriers. Relapses can occur several times a year, which leads to disability and impairs the quality of life. Currently, there are a large number of drugs for general and local treatment. However, they are toxic and can cause allergic reactions. In recent years, a large number of studies have been devoted to the use of lasers in the treatment of dental diseases. Therefore, the question of the use of a laser in the treatment of herpetic lesions of the oral cavity remains relevant.Purpose. The research purpose was to determine the effectiveness of the use of a diode laser in the treatment of herpetic lesions of the lips.Materials and methods. We conducted a comparative assessment of the effectiveness of the use of a diode laser in monotherapy of herpetic lip lesions in 18 patients. The comparison group consisted of 18 patients, in the local treatment of which antiviral ointments were used.Results. The results of the study showed that the use of a diode laser can reduce treatment time, accelerate the epithelization of foci.Conclusion. The results of our study allow us to recommend the use of a diode laser in the complex treatment of herpetic lesions of the oral cavity.

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0897 Low Stability In Rest Activity Rhythms Is Associated With Higher Suicidal Ideation In Adolescents With Bipolar Disorder

SLEEP ◽

10.1093/sleep/zsz067.895 ◽

2019 ◽

Vol 42 (Supplement_1) ◽

pp. A360-A361

Author(s):

Qianyi Chen ◽

Peter Franzen ◽

Tina Goldstein ◽

Sarah Gratzmiller

Keyword(s):

Bipolar Disorder ◽

Suicidal Ideation ◽

Activity Rhythms ◽

Rest Activity

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What Has Clinical Research in Suicide Prevention Done for You Lately?

CNS Spectrums ◽

10.1017/s1092852900014644 ◽

2006 ◽

Vol 11 (6) ◽

pp. 440-441 ◽

Cited By ~ 1

Author(s):

Jan Fawcett

Keyword(s):

Suicidal Ideation ◽

Suicide Risk ◽

Clinical Status ◽

Panic Attacks ◽

Current Evidence ◽

Suicide Risk Assessment ◽

Short Term ◽

The Past ◽

Standard Risk ◽

Suicide Plan

What have you heard or read over the past 10 years that has improved you ability to assess and manage suicide risk in your patients?There has been a paucity of data. What little data there is reviewed in this month's articles.They highlight findings that you should know about. Clinicians seem to cling to the familiar, unless some intense marketing is done.For instance, are you aware that the current evidence shows that a denial of suicide thoughts, plans, or intent—even a contract for safety—means absolutely nothing in the absence of a full suicide risk assessment?Yet clinicians seem to rely on these ’reassurances“ from their patients and are shocked when the patient later commits suicide. Why should a patient who is deciding that life is too painful to live tell you the truth? Robert I. Simon, MD, and Daniel W. Shuman, JD, review these facts.Are you aware that severe psychic anxiety, panic attacks, agitation, and severe insomnia often precede suicide within hours, days, or weeks and can be rapidly modified with treatment?On the other hand, standard risk factors for suicide such as suicidal ideation, hopelessness, and past suicidal attempts are not good predictors of suicide in the short term. A suicide plan, recent high intent attempt, or refusal to contract for safety may well indicate immediate risk, but a denial of suicidal ideation or intent and a contract for no harm mean absolutely nothing without a full suicide assessment that takes current clinical status, past suicidal tendencies, social support, and willingness to accept help into account.

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Suicidal Ideation Profiles in Patients with Fibromyalgia Using Transdiagnostic Psychological and Fibromyalgia-Associated Variables

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18010209 ◽

2020 ◽

Vol 18 (1) ◽

pp. 209

Author(s):

Jorge L. Ordóñez-Carrasco ◽

María Sánchez-Castelló ◽

Elena P. Calandre ◽

Isabel Cuadrado-Guirado ◽

Antonio J. Rojas-Tejada

Keyword(s):

Suicidal Ideation ◽

High Risk ◽

Suicide Risk ◽

Fibromyalgia Impact Questionnaire ◽

Cross Sectional Study ◽

Psychological Pain ◽

Cross Sectional ◽

Psychological Variables ◽

Interpersonal Needs Questionnaire ◽

High Degree

Several studies have emphasized the heterogeneity of fibromyalgia patients. Furthermore, fibromyalgia patients are considered a high-risk suicide group. The ideation-to-action framework proposes a set of transdiagnostic psychological factors involved in the development of suicidal ideation. The present study aims to explore the existence of different subgroups according to their vulnerability to suicidal ideation through these transdiagnostic psychological variables and a set of variables typically associated with fibromyalgia. In this cross-sectional study, 151 fibromyalgia patients were assessed through the Revised Fibromyalgia Impact Questionnaire, Beck Depression Inventory-II, Plutchik Suicide Risk Scale, Interpersonal Needs Questionnaire, Defeat Scale, Entrapment Scale, Psychache Scale, and Beck Hopelessness Scale. A K-means cluster analysis identified two clusters, one (45.70%) according to a low vulnerability, and a second (54.30%) with a high vulnerability to suicidal ideation. These clusters showed statistically significant differences in suicidal ideation and suicide risk. However, no differences were observed in most socio-demographic variables. In conclusion, fibromyalgia patients who present a clinical condition characterized by a moderate-high degree of physical dysfunction, overall disease impact and intensity of fibromyalgia-associated symptoms, along with a high degree of perceived burdensomeness, thwarted belongingness, defeat, entrapment, psychological pain and hopelessness, form a homogeneous group at high risk for suicidal ideation.

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