Growth curves in Down syndrome with congenital heart disease

SUMMARY Introduction: To assess dietary habits, nutritional status and food frequency in children and adolescents with Down syndrome (DS) and congenital heart disease (CHD). Additionally, we attempted to compare body mass index (BMI) classifications according to the World Health Organization (WHO) curves and curves developed for individuals with DS. Method: Cross-sectional study including individuals with DS and CHD treated at a referral center for cardiology, aged 2 to 18 years. Weight, height, BMI, total energy and food frequency were measured. Nutritional status was assessed using BMI for age and gender, using curves for evaluation of patients with DS and those set by the WHO. Results: 68 subjects with DS and CHD were evaluated. Atrioventricular septal defect (AVSD) was the most common heart disease (52.9%). There were differences in BMI classification between the curves proposed for patients with DS and those proposed by the WHO. There was an association between consumption of vitamin E and polyunsaturated fatty acids. Conclusion: Results showed that individuals with DS are mostly considered normal weight for age, when evaluated using specific curves for DS. Reviews on specific curves for DS would be the recommended practice for health professionals so as to avoid precipitated diagnosis of overweight and/or obesity in this population.

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Nutritional Status in Children with Congenital Heart Disease: Prevalence and Its Associated Factors

Paediatrica Indonesiana ◽

10.14238/pi38.1-2.1998.38-46 ◽

2017 ◽

Vol 38 (1-2) ◽

pp. 38

Author(s):

Rafner Lndra ◽

Tina Christina L Tobing ◽

Ahmad Dian Siregar ◽

Abdullah Afif Siregar ◽

Endang D Hamid ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Tract Infection ◽

Nutritional Status ◽

Respiratory Tract ◽

Respiratory Tract Infection ◽

Congenital Heart ◽

Acute Respiratory Tract Infection ◽

Cross Sectional ◽

Height For Age

A cross sectional study was undertaken on 58 children (age range 4 months-15 years) With congenital heart disease (CHD) and in controls of 58 subjects without CHD. The study was performed by anthropometric examination, history of acute respiratory tract infection, dietary intake, simple laboratory examination and type and severity of CHD were recorded. There were significant differences in: 1. Nutritional status between patients With CHD and without CHD (p<0.001). 2. Frequency of acute respiratory tract infection between patients with CHD and without CHD (p<0.001). 3. Duration of each episode of acute respiratory tract infection between patients with CHD and without CHD (p<0.05). 4. Calorie and protein intakes between patients with CHD and without CHD (p<0.005). Type of CHD (cyanotic and non-cyanotic) was significantly associated with nutritional status based on height for age among patients with CHD (p<0.01). However, there was no siignificant association between the presence or absence of heart failure with nutritional status among patients with CHD. In conclusion, there were Significantly differences of nutritional status, frequency/duration of acute respiratory tract infection, calories and protein intake between patients with CHD and without CHD. Type of CHD (cyanotic and non-cyanotic) was significantly associated with nutritional status based on height for age.

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Assessment of quality of life among parents of children with congenital heart disease using WHOQOL-BREF: a cross-sectional study from Northwest Saudi Arabia

Health and Quality of Life Outcomes ◽

10.1186/s12955-019-1249-z ◽

2019 ◽

Vol 17 (1) ◽

Author(s):

Saad Khoshhal ◽

Khaled Al-Harbi ◽

Ibrahim Al-Mozainy ◽

Saeed Al-Ghamdi ◽

Adnan Aselan ◽

...

Keyword(s):

Quality Of Life ◽

Congenital Heart Disease ◽

Heart Disease ◽

Internal Consistency ◽

Congenital Heart ◽

Cross Sectional Study ◽

World Health ◽

Sectional Study ◽

Cross Sectional

Abstract Background and aims Health-related quality of life (HRQOL) has garnered increasing interest especially for health care providers and researchers. The study aims to evaluate the HRQOL in parents of congenital heart disease (CHD) children, and to clarify the effect of the disease severity on the outcome of the HRQOL perception. Also, to analyze the internal consistency of the Arabic version of the World Health Organization (WHO) QOL-BREEF tool in order to determine whether the tool had good validity for the target population. Methods A cross-sectional study. The HRQOL perception was evaluated using WHOQOL-BREF questionnaire, and the internal consistency of the tool was tested using Cronbach’s alpha (α-C), Results The study sample consisted of 200 individuals, 120 parents of CHD children, compared to 80 parents of children with minor illnesses (mean age of participating parents = 35.1 ± 9.8 years). While evaluating the HRQOL, the group of parents of children with minor illnesses had higher scores than the total group of parents of CHD children in all domains, indicating a better HRQOL. Class-IV subgroup of parents of CHD children showed the most significant lower total score of domains between all classes (44.47 ± 12, p < 0.001). With respect to the internal consistency of the WHOQOL-BREF, estimation of α-C values were 0.84 points for the group of parents of CHD children, and 0.87 for the group of parents of children with minor illnesses. Conclusions This short-term study emphasized that, HRQOL scores among parents of CHD children are compromised, and the severity of their children illness significantly affect the total score of domains in their HRQOL perception. Furthermore, the tool showed to be practical and efficient to evaluate the QOL of parents of CHD children in our population in future researches.

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Dietary Habits and Nutritional Status of Undergraduate Students of Winneba Campus of University of Education, Winneba, Ghana

10.46715/jfsn2020.10.1000109 ◽

2020 ◽

pp. 1-10

Author(s):

Janet AgyarkwaaOti ◽

Guy Eshun

Keyword(s):

Nutritional Status ◽

Nutrition Education ◽

Undergraduate Students ◽

Dietary Habits ◽

Sampling Technique ◽

Normal Weight ◽

The Body ◽

World Health ◽

Cross Sectional ◽

The University

Even though empirical evidence exists to validate the avowal that dietary habits hold the key in reducing the surge in non-communicable diseases among adolescents and young adults and for optimal nutritional status, little is known about the nexus of these variables in the Ghanaian context and much less in Ghanaian universities. In view of this dearth in literature, this study investigated dietary habits and its effect on nutritional status among undergraduate students of the Winneba Campus of University of Education, Winneba. Using the Social-Ecological Model (SEM) as the theoretical basis, this study adopted the cross-sectional descriptive survey research design with the quantitative approach where proportionate stratified random sampling technique was used to select 3,065 students for the study. The assessment of nutritional status was done where height and weight were measured in Kg/m2and the body mass index (BMI) was calculated based on the recommendations by the World Health Organization. Data on the dietary habits was collected with a closed-ended questionnaire which was analyzed using both descriptive statistics like frequency, percentages, mean, standard deviation as well as inferential statistics such as multiple regression.The study discovered that undergraduate students of the University of Education, Winneba, were of normal weight than overweight and underweight while obesity was ranked the least. The study further revealed that even though students moderately consumed fish, meat, eggs and dairy products legumes and nuts, they had a low intake of fruits and vegetables, but high consumption of energy-dense foods and fast foods such as cakes, pastries, cookies, deep-fried foods, biscuits, sandwiches, indomie and of soft drinks. It was further established that majority of the students skipped meals notably breakfast. Besides, the study showed that all the dietary habits outlined in the study collectively contributed significantly to students’ nutritional status. Therefore, it is recommended that the University through its health directorate and the Department of Food and Nutrition should regularly organize health talks and symposiums to admonish students on the dangers of not observing optimal dietary habits. Additionally, the University through its Academic Board should introduce a general course on nutrition education to equip students with current theories in dietary practices for improved dietary habits.

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Nutritional Status and Pulmonary Hypertension in Children with Down Syndrome Presenting with Congenital Heart Disease: Retrospective Study

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2020/v32i2030676 ◽

2020 ◽

pp. 12-18

Author(s):

J. M. Chinawa ◽

O. C. Duru ◽

B. F. Chukwu ◽

A. T. Chinawa

Keyword(s):

Congenital Heart Disease ◽

Pulmonary Hypertension ◽

Down Syndrome ◽

Heart Disease ◽

Retrospective Study ◽

Nutritional Status ◽

Congenital Heart ◽

Children With Down Syndrome ◽

Increased Risk ◽

Hypertension In Children

Introduction: Children with Down syndrome are predisposed to having congenital heart defect. Objectives: This study is aimed to describe the clinical correlates, nutritional status and pulmonary hypertension in children with Down syndrome who presented with congenital heart disease. Patients and Methods: A retrospective study of children with Down syndrome who presented with congenital heart disease from 2016 to 2020 was carried out. Nutritional status was assessed with WHO Anthro software while pulmonary hypertension was assessed with standard procedures. Results: Out of 758 echocardiography done over the period of 5 years for children suspected of having cardiac disease, three hundred and eight one had confirmed congenital heart disease of which twenty-eight of them had Down syndrome 7.34% (28/381). Ten 10/28 (35.7%) of them had pulmonary hypertension. This is commonly noted among infants than older ages. Among 28 children with Down syndrome, twenty-three had complete information for weight and height which was used to assess their nutritional status, 47.8% (11/28) presented with wasting and stunted, 8.7% (2/28) of those with Down syndrome were wasted and 8.7% (2/28) with stunting. Down syndrome is commoner in children with AV canal defect 50% (14/28) followed by PDA 21.4% (6/14). Fast breathing 86.7% (13/15) as the most common symptom followed by cough 64.3% (9/14) Conclusion: Children with Down syndrome who had congenital heart disease are at increased risk of malnutrition and pulmonary hypertension.

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The Association between Cyanotic and Acyanotic Congenital Heart Disease with Nutritional Status

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2020.3978 ◽

2020 ◽

Vol 8 (B) ◽

pp. 245-248

Author(s):

Putri Amelia ◽

Rizky Adriansyah ◽

Bastian Lubis ◽

Muhammad Akil

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Nutritional Status ◽

Congenital Heart ◽

Heart Defects ◽

Cross Sectional Study ◽

Common Finding ◽

Nutrient Inputs ◽

Prevalence Odds Ratio ◽

Cross Sectional

BACKGROUND: Congenital heart disease (CHD) is one of the most common birth anomalies in the 1st year of life. The incidence of CHD in developed and developing countries is varied, between 6 and 10 cases per 1000 live birth. Some factors contribute to the nutritional status of CHD patients, such as nutrient inputs, energy requirements, and dietary components. Irrespective of the nature of the cardiac defect and the presence or absence of cyanosis, malnutrition is a common finding in children with congenital heart anomalies. Recent studies have tried to investigate malnutrition development based on the type or category of CHD. AIM: This study aims to investigate the association between cyanotic and acyanotic CHD with nutritional status. METHODS: A cross-sectional study was conducted from January to March 2018 in the pediatric cardiology outpatient clinic of the Haji Adam Malik General Hospital, Medan, Indonesia. RESULTS: During the study period, 58 children were admitted, consisting of 31 (53.4%) males and 27 (46.6%) females, with a mean age of 57 months. There was no significant sex predilection found in the study (p = 0.207). The proportion of patients who developed malnutrition was 70.7% (mild-moderate = 48.3% and severe = 22.4%). There was an association between cyanotic and acyanotic CHD with nutritional status (p = 0.015). Wasting was found in 33 children (56.8%) that had a significant association with the type of heart defects (p = 0.001). Patients with cyanotic CHDs were found to have a lower risk for malnutrition compared to the acyanotic group (prevalence odds ratio = 0.218, and prevalence risk = 0.661; p = 0.015). CONCLUSIONS: There is an association between cyanotic and acyanotic CHD with nutritional status.

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Prevalence of extracardiac malformations associated with congenital heart disease

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20180526 ◽

2018 ◽

Vol 5 (2) ◽

pp. 411

Author(s):

Sailen Kumar Bana ◽

Asok Mandal Mandal ◽

Niranjan Nagaraj ◽

Sameer Saraswati ◽

Ankush Shukla

Keyword(s):

Congenital Heart Disease ◽

Down Syndrome ◽

Heart Disease ◽

Congenital Heart ◽

Heart Diseases ◽

Structural Abnormality ◽

Cross Sectional ◽

General Physical Examination ◽

General Physical ◽

Systemic Examination

Background: Congenital heart disease is defined as a gross structural abnormality of the heart or intrathoracic great vessels that is actually or potentially of functional significance. This study aims to know the prevalence of occurrence of extra cardiac malformations in patients with CHD, based on clinical features and necessary investigations when required and to study whether these extracardiac malformations occur as a part of a known syndrome or they occur in isolation.Methods: This study is a cross sectional hospital based observational study, carried out in the Department of Paediatrics, Dr. B. C. Roy Postgraduate Institute of Paediatric Sciences, Kolkata over two years from July 2014 to June 2016. A thorough general physical examination, vitals, anthropometry was undertaken. Systemic examination was done in all cases according to the study proforma. CHD was confirmed by X-ray chest, Electrocardiography, Echocardiography.Results: Twenty-three percentages (23%) of the patients were found to have an associated major ECM. Down syndrome was the most commonly identified syndrome in the present study accounting for 50% of the patients of CHD with an associated syndrome. The most common CHD among patients with Down syndrome were multiple CHD and VSD.Conclusions: Whenever more than 1 minor anomalies are found, a careful search for an underling major malformation such as CHD should be made. In all cases of congenital heart diseases with associated extracardiac malformations, effort should be made by the treating pediatrician to rule out an associated syndrome; so that parents can be counselled about prognosis, recurrence in the subsequent pregnancies.

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Cardiopatia congênita: estado nutricional e proporcionalidade corporal ao nascimento

Abr-Jun - Braspen Journal ◽

10.37111/braspenj.2020351004 ◽

2020 ◽

Vol 35 (1) ◽

pp. 13-19

Author(s):

Izabela dos Santos Pereira ◽

Cláudia Porto Sabino Pinho ◽

Adriana César da Silveira

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Nutritional Status ◽

Congenital Heart ◽

Heart Diseases ◽

Ponderal Index ◽

Congenital Heart Diseases ◽

Cyanotic Heart Disease ◽

Cross Sectional ◽

Using Data

Introduction: Congenital heart diseases have a great impact on perinatal and infant mortality rates in Brazil. These are diseases that can lead to compromised growth and development of the child. The purpose of this study is to describe the nutritional condition and the corporal proportionality to the birth of children with congenital heart disease. Methods: A cross-sectional, retrospective study using data on the birth of children with congenital heart disease admitted to a cardiology service in the Northeast of Brazil between 2011 and 2014. The nutritional status was assessed by weight/age (W/A) indicators, length/age, weight/length, body mass index/age (BMI/A), ponderal index, cephalic perimeter. Results: A total of 117 patients were evaluated, being 60.7% male and 20.9% with cyanotic heart disease. It was found that 6.8% of the children were low birth weight. The nutritional indexes showed a 3.4% deficit in the W/A indicator, in weight/length 5.1%, for BMI/A 4.3% and length/age 7.8%. The ponderal index showed that 28.2% of the children were disproportionate at birth and 84.4% had a normal head circumference. Lower Z score values of W/A (p = 0.030) and BMI/A (p = 0.023) for cyanotic heart disease compared to other types of congenital heart diseases were observed in our study. Conclusions: Children with congenital heart disease had relatively preserved nutritional status at birth, with prevalence of nutritional disorders similar to those described in the literature.

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Nutritional status of children with congenital heart disease

Revista Latino-Americana de Enfermagem ◽

10.1590/s0104-11692012000600003 ◽

2012 ◽

Vol 20 (6) ◽

pp. 1024-1032 ◽

Cited By ~ 5

Author(s):

Flávia Paula Magalhães Monteiro ◽

Thelma Leite de Araujo ◽

Marcos Venícios de Oliveira Lopes ◽

Daniel Bruno Resende Chaves ◽

Beatriz Amorim Beltrão ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Nutritional Status ◽

Congenital Heart ◽

Skinfold Thickness ◽

Cross Sectional Study ◽

Acute Malnutrition ◽

Cross Sectional ◽

Z Scores ◽

Nutritional Status Of Children

OBJECTIVE: to characterize nutritional status and variables that predict nutritional changes in children with congenital heart disease. METHOD: a cross-sectional study undertaken in two health institutions between January and June 2009, using a questionnaire with questions about nutrition, applied to 132 children under two years of age who had congenital heart disease. Children who had additional serious illnesses were excluded. RESULT: the predominant percentile values and Z scores were concentrated within the range of normal levels. The Z scores, however, presented negative variations with a deviation to the left. In the analysis of predictive factors, the occurrence of immediate and acute malnutrition was related to a decrease in skinfold thickness (decrease in subscapular skinfold thickness, while immediate malnutrition was related to a high Apgar score. Chronic malnutrition was related to female children with higher ages. CONCLUSION: it is evidenced that it is necessary to carry out nutritional strategies which improve prognosis, so as to widen the nursing care directed at these children.

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Galectin-3 plasma levels in adult congenital heart disease and the pressure overloaded right ventricle: reason matters

Biomarkers in Medicine ◽

10.2217/bmm-2020-0250 ◽

2020 ◽

Vol 14 (13) ◽

pp. 1197-1205

Author(s):

Ewa Kowalik ◽

Beata Kuśmierczyk-Droszcz ◽

Anna Klisiewicz ◽

Aleksandra Wróbel ◽

Anna Lutyńska ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Congenital Heart ◽

Adult Congenital Heart Disease ◽

Clinical Status ◽

Pressure Overload ◽

Cross Sectional ◽

Galectin 3 ◽

Congenitally Corrected Transposition ◽

Corrected Transposition

Aim: To assess galectin-3 (Gal-3) levels and their relationship with clinical status and right ventricular (RV) performance in adults with RV pressure overload of various mechanisms due to congenital heart disease. Materials & methods: A cross-sectional study was conducted. Patients underwent clinical examination, blood testing and transthoracic echocardiography. Results: The study included 63 patients with congenitally corrected transposition of the great arteries, 41 patients with Eisenmenger syndrome and 20 healthy controls. Gal-3 concentrations were higher in patients compared with controls (7.83 vs 6.11 ng/ml; p = 0.002). Biomarker levels correlated with age, New York Health Association class, N-terminal probrain natriuretic peptide and RV function only in congenitally corrected transposition of the great arteries patients. Conclusion: Gal-3 profile in congenital heart disease patients and pressure-overloaded RV differs according to the cause of pressure overload.

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Down syndrome and congenital heart disease: perioperative planning and management

Journal of Congenital Cardiology ◽

10.1186/s40949-021-00061-3 ◽

2021 ◽

Vol 5 (1) ◽

Author(s):

Dennis R. Delany ◽

Stephanie S. Gaydos ◽

Deborah A. Romeo ◽

Heather T. Henderson ◽

Kristi L. Fogg ◽

...

Keyword(s):

Congenital Heart Disease ◽

Down Syndrome ◽

Cardiac Surgery ◽

Heart Disease ◽

Congenital Heart ◽

Single Ventricle ◽

Heart Defects ◽

Careful Consideration ◽

Children With Down Syndrome ◽

Perioperative Planning

AbstractApproximately 50% of newborns with Down syndrome have congenital heart disease. Non-cardiac comorbidities may also be present. Many of the principles and strategies of perioperative evaluation and management for patients with congenital heart disease apply to those with Down syndrome. Nevertheless, careful planning for cardiac surgery is required, evaluating for both cardiac and noncardiac disease, with careful consideration of the risk for pulmonary hypertension. In this manuscript, for children with Down syndrome and hemodynamically significant congenital heart disease, we will summarize the epidemiology of heart defects that warrant intervention. We will review perioperative planning for this unique population, including anesthetic considerations, common postoperative issues, nutritional strategies, and discharge planning. Special considerations for single ventricle palliation and heart transplantation evaluation will also be discussed. Overall, the risk of mortality with cardiac surgery in pediatric patients with Down syndrome is no more than the general population, except for those with functional single ventricle heart defects. Underlying comorbidities may contribute to postoperative complications and increased length of stay. A strong understanding of cardiac and non-cardiac considerations in children with Down syndrome will help clinicians optimize perioperative care and long-term outcomes.

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