scholarly journals Factors related to patient adherence to the use of new oral anticoagulants

Author(s):  
Paula Rocco Gomes Lima ◽  
Gisele Mara Silva Gonçalves ◽  
Roberta Cunha Matheus Rodrigues ◽  
Ana Railka de Souza Oliveira-Kumakura

ABSTRACT Objective: To characterize the self-reported adherence of patients with cardiovascular diseases to the use of new oral anticoagulants and to identify factors related to adherence to these drugs. Method: This is a descriptive, correlational, and cross-sectional study, carried out with outpatients. The collection of sociodemographic, clinical, and adherence data, through the Measurement of Adherence to Treatments, was made through telephone calls. Descriptive, correlation, and multiple linear regression analyses were used. Results: A total of 120 patients using new anticoagulants for 32.3 months, on average, participated in the study. More than half of the sample consisted of women, who were professionally inactive, with a mean age of 70.1 years and a mean family income of 6.7 minimum wages. The mean adherence score was 5.7, in a possible range between 1 and 6, indicating medication adherence. Inactive employment status, female sex, higher family income, and follow-up at a public outpatient clinic were related to greater adherence to these medications. Conclusion: The patients showed high adherence to new anticoagulants. Employment status, sex, family income, and type of outpatient follow-up were related to medication adherence, and should be considered in the design of interventions for this public.

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Ahmad Aliyu ◽  
Babatunde Adelekan ◽  
Nifarta Andrew ◽  
Eunice Ekong ◽  
Stephen Dapiap ◽  
...  

Abstract Background Expanded access to antiretroviral therapy (ART) leads to improved HIV/AIDS treatment outcomes in Nigeria, however, increasing rates of loss to follow-up among those on ART is threatening optimal standard achievement. Therefore, this retrospective cross-sectional study is aimed at identifying correlates and predictors of loss to follow-up in patients commencing ART in a large HIV program in Nigeria. Methods Records of all patients from 432 US CDC Presidents Emergency Plan for AIDS Relief (PEPFAR) supported facilities across 10 States and FCT who started ART from 2004 to 2017 were used for this study. Bivariate and multivariate analysis of the demographic and clinical parameters of all patients was conducted using STATA version 14 to determine correlates and predictors of loss to follow-up. Results Within the review period, 245,257 patients were ever enrolled on anti-retroviral therapy. 150,191 (61.2%) remained on treatment, 10,960 (4.5%) were transferred out to other facilities, 6926 (2.8%) died, 2139 (0.9%) self-terminated treatment and 75,041 (30.6%) had a loss to follow-up event captured. Males (OR: 1.16), Non-pregnant female (OR: 4.55), Patients on ≥ 3-monthly ARV refills (OR: 1.32), Patients with un-suppressed viral loads on ART (OR: 4.52), patients on adult 2nd line regimen (OR: 1.23) or pediatric on 1st line regimen (OR: 1.70) were significantly more likely to be lost to follow-up. Conclusion Despite increasing access to anti-retroviral therapy, loss to follow-up is still a challenge in the HIV program in Nigeria. Differentiated care approaches that will focus on males, non-pregnant females and paediatrics is encouraged. Reducing months of Anti-retroviral drug refill to less than 3 months is advocated for increased patient adherence.


2019 ◽  
Vol 10 (2) ◽  
pp. 203
Author(s):  
Siti Julaiha

<p>Diabetes mellitus is a chronic metabolic disease known as a deadly killer. Indonesia ranks 5th in the world in the number of people with Diabetes Mellitus in 2014. Poor medication adherence can increase microvascular and microvascular complications that cause damage to organs such as fat, heart, brain, and eyes. Patient adherence can be measured using a questionnaire 8- Morisky item Medication adherence Scale (MMAS-8). This instrument can be used to measure medication adherence in patients with chronic diseases such as hypertension, diabetes mellitus, tuberculosis, etc. This study aimed to analyze the factors associated with Medication Adherence Based On MMAS-8 Score to Type 2 Diabetes Mellitus Outpatient at Mardi Waluyo Hospital Metro in 2018. This research is an analytic observational study with a design cross-sectional study. The population of this study was type 2 DM outpatients who were treated at Mardi Waluyo Hospital Metro in 2018. The data collected were the results of research using the MMAS-8 questionnaire. Data were analyzed by using chi-square and multivariate logistic regression method. Result of this study showed that the patient who has income &lt;Rp 2,100,000 risk nonadherence 2,981 times higher than a patient who has an income of ≥Rp.2,100,000. Patients with primary education risk nonadherence 2.724 times higher than patients with further education.</p><p> </p>


2021 ◽  
pp. 004947552110448
Author(s):  
Subramani Jagadeesan ◽  
Subramanian Muthathal ◽  
Archismita Santra

In India, the world's second most populous state, an increasing proportion of its population are elderly. Older people invariably face special psychiatric challenges. In a community-based cross-sectional study, depression was found to be present in almost a third of the elderly; furthermore, low family income, poor literacy and uncertain employment status were found to be significant associations.


2012 ◽  
Vol 20 (1) ◽  
pp. 59-72 ◽  
Author(s):  
Elizabeth Salt ◽  
Lynne Hall ◽  
Ann R. Peden ◽  
Rob Horne

Patient adherence to their health care protocols is important to encourage the best health outcomes in rheumatoid arthritis (RA); however, little attention has been given to assessing the psychometric properties of adherence measures in this patient population. The purpose of this study was to evaluate the psychometric properties of three existing self-report measures of medication adherence in a sample of patients with RA—the Compliance-Questionnaire-Rheumatology (CQR), the Medication Adherence Report Scale (MARS), and the Medication Adherence Scale (MAS). A cross-sectional study of 108 clinic patients with rheumatoid arthritis was conducted to evaluate the reliability and validity of the measures. Cronbach’s alpha was .77 for both the CQR and a modified version of the MARS. For the MAS, the Kuder-Richardson 20 reliability was .25. Although not strong, test-retest reliability was adequate for all measures. Factor analysis indicated that both the MARS and the CQR measure two factors. All three instruments were moderately correlated with each other, with correlations ranging between .48 and .56. Although these scales were significantly correlated, moderate correlations among the scales indicate that they may not measure the same aspects of adherence. Among the three adherence measures, the modified MARS demonstrated the best evidence of reliability and validity and ease of administration in this sample of persons with RA.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Henok Tadele ◽  
Hayat Ahmed ◽  
Helen Mintesnot ◽  
Etsegenet Gedlu ◽  
Senbeta Guteta ◽  
...  

Abstract Background Subjective wellbeing (SWB) is a self-reported positive life judgment and good feeling. RHD, rheumatic heart disease, is a long-term sequel of single or recurrent acute rheumatic fever. There are no studies that assessed SWB in RHD patients. We aimed to assess SWB among RHD subjects enrolled in chronic care at Tikur Anbessa Specialized Hospital (TASH), Ethiopia. Methods This observational cross-sectional study employed a validated Amharic WHO-5 wellbeing index to assess SWB. Sociodemographic and clinical data were collected using structured questionnaire. RHD subjects aged 9 years and above were included. Factors associated with SWB were assessed using logistic regression models. Results The study included 384 subjects, females 68.2% (262). Children, < 18 years, constituted one third of study subjects, 32.8% (126). Moderate and severe echocardiographic RHD dominated, 85.9% (330) with no associated comorbidity, 84.4% (324). Only 17.2% (66) had surgical or device intervention. Poor SWB was documented in 9.6% of study subjects (95% CI: 6.88–13.04). On multivariable regression, those with younger age RHD diagnosis, < 20 years, had almost three times higher odds of poor SWB, adjusted odds ratio (aOR) 2.69(95% CI: 1.30–5.58, P 0.008). Those with monthly family income of < 1000 Ethiopian Birr had three times higher odds of poor SWB, aOR 2.97(95% CI: 1.24–7.1, P 0.014). Study subjects who had good medication adherence had reduced odds of poor SWB, aOR 0.37(95% CI: 0.18–0.77, P 0.028). Those who received psychologic support from their families also had reduced odds of poor SWB, aOR 0.26(95% CI: 0.11–0.64, P 0.003). Conclusion Poor SWB was documented in one-tenth of RHD patients. Family income, younger age at RHD diagnosis, medication adherence and psychological support predicted poor SWB. Poor SWB has to be considered and assessed among RHD patients particularly among those with younger age at RHD diagnosis and poor family income. Further mixed studies are recommended to assess how medication adherence and psychological supports associate with positive SWB among RHD patients.


2021 ◽  
Vol 36 (1) ◽  
pp. eURJ3975
Author(s):  
Carolina Kobbaz Ferraresso ◽  
◽  
Francine Neves ◽  
Lara Elisa De Freitas Campos ◽  
Luísa Diniz Marra Vieira ◽  
...  

The levels of anxiety and the use of medication among medical students were evaluated, relating it to sociodemographic data, prescription and medical follow-up, and symptom improvement. Cross-sectional study, in which a semi-structured questionnaire was applied. Among 264 students interviewed, 21% of the total (n = 56) use medication to treat anxiety. Most of them are female, almost half between 21 and 25 years old, single, live alone, and have high family income. These students opted for medical school mainly for professional and personal achievement, and the main drug used is fluoxetine. Yet, among drug users (n = 56), 39% (n = 22) self-medicate, although 64.3% (n = 36) are under medical supervision, more than half have side effects and 87.5% (n = 49) showed improvements in anxiety symptoms after starting use. The use of medication to treat anxiety was statistically related to monthly income, type of housing and reason for choosing the course (p < 0.05), although other variables cannot be ruled out. As noted in the present study, the use of such medications among medical students is considerable and, for the most part, medical follow-up directly influences the improvement of symptoms. In addition, there are risk factors related to the sociodemographic profile, which can lead to anxiety and/or self-medication and the indiscriminate use of medication, so preventive health measures must take these factors into account to guide more effective actions.


2021 ◽  

Background: The effectiveness of autologous stem cell transplantation (ASCT) in patients with relapsed/refractory lymphoma is accepted by all authors. After ASCT, 5-year overall-survival (OS) rates can reach up to 80%. However, returning to work-life after ASCT and the employment status of these patients are unknown. Objectives: Our aim in this study is to examine the rate of not-return to work in the post-treatment period and the factors that may affect employment status in patients who underwent ASCT with the diagnosis of relapsed/refractory lymphoma. Methods: This cross-sectional study was conducted between January 2020 - June 2020. Patients between the ages of 18-65, who underwent ASCT with the diagnosis of relapsed or refractory lymphoma and who were in remission without recurrence one-year after ASCT were included in the study. Results: Eighty (74.8%) of 107 patients included in the study were male, and the median age was 49.0 (21-63). The number of primary school graduates was 66 (61.7%). Most of the patients were married (n = 90, 84.1%). Before ASCT, 30 (28.0%) patients were in the private sector, 17 (15.9%) were in their own workplace. Median follow-up time was 34.8 months (12.4 - 124.7 months). During this follow-up period 35 (57.3%) of 61 patients did not return to work. Most of these patients had retired (n=29, 47.5%). It was seen that having a higher education level (OR: 0.32 (0.14-1.22) 95% CI, p:0.041) and public employee (OR: 0.30 (0.12-0.97) 95% CI, p:0.033) are independent factors that reduce the risk of not-returning to work. Conclusion: It was observed that more than half of our patients did not return to work. Low level of education and sectors other than public-employee pose a risk for not returning to work. It may be possible for patients to return to work with well-planned options such as part-time.


2021 ◽  
Vol 13 (1) ◽  
pp. 126-135
Author(s):  
Phuong M. Nguyen ◽  
Anh N. Thach ◽  
Xuan D. Pham ◽  
Anh N. Lam ◽  
Thao N. P. Nguyen ◽  
...  

This study was conducted to determine the prevalence and determinants of medication adherence among patients with HIV/AIDS in southern Vietnam. Methods: A cross-sectional study was conducted in a hospital in southern Vietnam from June to December 2019 on patients who began antiretroviral therapy (ART) for at least 6 months. Using a designed questionnaire, patients were considered adherent if they took correct medicines with right doses, on time and properly with food and beverage and had follow-up visits as scheduled. Multivariable logistic regression was used to identify determinants of adherence. Key findings: A total of 350 patients (from 861 medical records) were eligible for the study. The majority of patients were male (62.9%), and the dominant age group (≥35 years old) accounted for 53.7% of patients. Sexual intercourse was the primary route of transmission of HIV (95.1%). The proportions of participants who took the correct medicine and at a proper dose were 98.3% and 86.3%, respectively. In total, 94.9% of participants took medicine appropriately in combination with food and beverage, and 75.7% of participants were strictly adherent to ART. The factors marital status (odds ratio (OR) = 2.54; 95%CI = 1.51–4.28), being away from home (OR = 1.7; 95%CI = 1.03–2.78), substance abuse (OR = 2.7; 95%CI = 1.44–5.05), general knowledge about ART (OR = 2.75; 95%CI = 1.67–4.53), stopping medication after improvement (OR = 4.16; 95%CI = 2.29–7.56) and self-assessment of therapy adherence (OR = 9.83; 95%CI = 5.44–17.77) were significantly associated with patients’ adherence. Conclusions: Three-quarters of patients were adherent to ART. Researchers should consider these determinants of adherence in developing interventions in further studies.


Sign in / Sign up

Export Citation Format

Share Document