Physical activity and quality of life of children and adolescents with cystic fibrosis: a cross-sectional study

Abstract Introduction: Regular physical activity (PA) is part of outpatient care offered to most people with cystic fibrosis (CF). Objective: To determine the frequency of the self-reported PA and, secondarily evaluate associations between PA with clinical variables and health-related quality of life (HRQoL) in pediatric and adolescent CF subjects. Method: In this cross-sectional study, subjects between 6 and 17 years of age with a confirmed diagnosis of CF were recruited in the outpatient clinic. The subjects answered questions about the practices of PA, HRQoL questionnaire and clinical variables were collected. Subjects were classified into two groups according to weekly PA practice: PA performed ≥ 3 times/week and performed PA ≤ 2 times/week. Results: 66 subjects completed the study, 72.7% (n=48) had PA ≥ 3 times/week and 27.2% (n=18) had PA ≤ 2 times/week. Only twelve children (18,2%) reached the recommendations of the World Health Organization (WHO) to practice moderate to vigorous physical activities daily. The mean age of the subjects evaluated was 12.3 ± 3.2 years, forced expiratory volume in one second 90 ± 24.1% and forced vital capacity 95 ± 20.4%. The group that performed PA ≥ 3 times/week had a better clinical score (p=0.033), a lower number of hospitalizations in the year (p=0.002), a lower number of days hospitalized in the last year (p=0.020) and better score for the physical (p=0.003) and emotion (p=0.048) domains in HRQoL questionnaire. Conclusion: This study concluded that most subjects did not reach the WHO recommendations for the practice of PA. However, individuals who practice PA at least 3 times/week have better HRQoL, clinical score and fewer hospitalizations.

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Engagement in a Community Physical Activity Program and Its Effects Upon the Health-Related Quality of Life of Elderly People: A Cross-Sectional Study

Value in Health Regional Issues ◽

10.1016/j.vhri.2018.10.002 ◽

2018 ◽

Vol 17 ◽

pp. 183-188 ◽

Cited By ~ 2

Author(s):

Claudio Andre Barbosa de Lira ◽

Henrique Viana Taveira ◽

Weverton Rufo-Tavares ◽

Alexandre dos Santos Amorim ◽

Lucas Matos Costa Ferreira ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Cross Sectional Study ◽

Health Related Quality ◽

Sectional Study ◽

Cross Sectional ◽

Activity Program ◽

Related Quality ◽

Health Related

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Leisure-time physical activity, anthropometrics, and body composition as predictors of quality of life domains after spinal cord injury: an exploratory cross-sectional study

Neural Regeneration Research ◽

10.4103/1673-5374.327356 ◽

2022 ◽

Vol 17 (6) ◽

pp. 1369

Author(s):

AshrafS Gorgey ◽

MelodyN Mickens ◽

Paul Perrin ◽

JacobA Goldsmith ◽

RefkaE Khalil ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Leisure Time ◽

Leisure Time Physical Activity ◽

Cross Sectional Study ◽

Life Domains ◽

Sectional Study ◽

Cross Sectional ◽

Cord Injury

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Estrogen Supplementation Is Associated With Higher Quality of Life Scores in Women With Cystic Fibrosis

Journal of the Endocrine Society ◽

10.1210/jendso/bvab048.1489 ◽

2021 ◽

Vol 5 (Supplement_1) ◽

pp. A732-A732

Author(s):

Malinda Wu ◽

Neha Arora ◽

Viranuj Sueblinvong ◽

William R Hunt ◽

Vin Tangpricha

Keyword(s):

Quality Of Life ◽

Cystic Fibrosis ◽

Estrogen Therapy ◽

Cross Sectional Study ◽

Rank Test ◽

Sectional Study ◽

Mineral Density ◽

Cross Sectional ◽

Domain Scores

Abstract Purpose: With rapid advancements in therapeutic options for patients with cystic fibrosis (CF), the median predicted survival has increased to 47 years along with the prevalence of non-pulmonary complications for patients with CF. Women with CF suffer irregular menses, sexual dysfunction and low bone mineral density. With increasing pregnancies among women with CF, they may consider contraception. Estrogen supplementation may modulate these outcomes and others. The purpose of this study was to explore the effects of supplemental estrogen use on quality of life (QOL) in CF. Methods: Women with CF ages 16-50 years were administered a validated CF-specific QOL survey (CFQ-R) during a routine CF clinic visit through an IRB-approved cross-sectional study. The QOL domain scores of subjects taking and not taking estrogen were compared pairwise by Kruskal Wallis tests and overall by Wilcoxon signed rank test. Results: The estrogen exposed and estrogen unexposed subjects with CF had similar age, BMI, FEV1, race, CF mutation, pancreatic insufficiency, diabetes and relationship status. The estrogen exposed subjects were taking 20-30 mcg of ethinyl estradiol in oral contraceptive pills. The estrogen exposed subjects had consistently higher QOL scores than the estrogen unexposed subjects (p=0.001). The estrogen exposed subjects had significantly higher scores in 7 of the 12 CFQ-R categories: physical, vitality, treatment burden and role domains and weight, respiratory and digestion symptom scales (p<0.05). When correcting for multiple comparisons, the estrogen-supplemented women had higher role domain scores than women not taking estrogen supplement (p=0.03). Conclusions: Estrogen supplementation was associated with improved quality of life in women with CF. This cross-sectional study highlights the need for further investigation into the potential benefits of estrogen supplementation. The dose, route, formulation and timing of estrogen therapy may modulate the beneficial effects for women with CF. Support: This work was supported by the National Center for Advancing Translational Sciences of the National Institutes of Health under award TL1TR002382 and UL1TR002378, and Cystic Fibrosis Foundation award WU20D0. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH or CFF.

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Self-perception: Does Obesity Influence Quality of Life

10.21203/rs.3.rs-37340/v2 ◽

2021 ◽

Author(s):

Amra Zalihic ◽

Maja Barbaric ◽

Mirela Mabic ◽

Marnela Palameta ◽

Ankica Mijic Maric ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Body Weight ◽

Cross Sectional Study ◽

Sectional Study ◽

Self Perception ◽

Cross Sectional ◽

Overweight People ◽

The World

Abstract The number of obese and overweight people around the world rapidly grows and takes on epidemic proportions. The aim of this research is to determine the influence of body weight on quality of life and to investigate our patients' consciousness about their body weight and its impact on their quality of life.Methods : The cross-sectional study was conducted by interviewing 1067 respondents, using the WHOQOL-BREF questionnaire.Results : Out of 1067 patients, 684 were females. 65.5 % of patients had BMI ≥25 kg/m 2 . 21.7% of 699 patients who had BMI ≥25 kg/m 2 think that their increased body weight doesn’t affect their health, 27.9 % of respondents think that their overweight is unrelated to physical activity, 41.8 % of respondents have no problems purchasing the clothes due to their weight and 31.6 % of respondents with BMI ≥25 kg/m 2 think that it doesn’t affect their quality of life.Conclusion : Quality of life is significantly better in respondents with BMI <25 kg/m 2 . The alarming result is that slightly less than half of respondents think that overweight doesn’t affect their health and don’t understand the seriousness of the problem.

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Associations between lifestyle factors and multidimensional frailty: a cross-sectional study among community-dwelling older people

BMC Geriatrics ◽

10.1186/s12877-021-02704-x ◽

2022 ◽

Vol 22 (1) ◽

Author(s):

Marcel A. L. M. van Assen ◽

Judith H. M. Helmink ◽

Robbert J. J. Gobbens

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Cross Sectional Study ◽

Lifestyle Factors ◽

Community Dwelling ◽

Sectional Study ◽

Physical Frailty ◽

Cross Sectional ◽

Community Dwelling Older People

Abstract Background Multidimensional frailty, including physical, psychological, and social components, is associated to disability, lower quality of life, increased healthcare utilization, and mortality. In order to prevent or delay frailty, more knowledge of its determinants is necessary; one of these determinants is lifestyle. The aim of this study is to determine the association between lifestyle factors smoking, alcohol use, nutrition, physical activity, and multidimensional frailty. Methods This cross-sectional study was conducted in two samples comprising in total 45,336 Dutch community-dwelling individuals aged 65 years or older. These samples completed a questionnaire including questions about smoking, alcohol use, physical activity, sociodemographic factors (both samples), and nutrition (one sample). Multidimensional frailty was assessed with the Tilburg Frailty Indicator (TFI). Results Higher alcohol consumption, physical activity, healthy nutrition, and less smoking were associated with less total, physical, psychological and social frailty after controlling for effects of other lifestyle factors and sociodemographic characteristics of the participants (age, gender, marital status, education, income). Effects of physical activity on total and physical frailty were up to considerable, whereas the effects of other lifestyle factors on frailty were small. Conclusions The four lifestyle factors were not only associated with physical frailty but also with psychological and social frailty. The different associations of frailty domains with lifestyle factors emphasize the importance of assessing frailty broadly and thus to pay attention to the multidimensional nature of this concept. The findings offer healthcare professionals starting points for interventions with the purpose to prevent or delay the onset of frailty, so community-dwelling older people have the possibility to aging in place accompanied by a good quality of life.

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Biosocial and disease conditions are associated with good quality of life among older adults in rural eastern Nepal: Findings from a cross-sectional study

PLoS ONE ◽

10.1371/journal.pone.0242942 ◽

2020 ◽

Vol 15 (11) ◽

pp. e0242942

Author(s):

Uday Narayan Yadav ◽

Tarka Bahadur Thapa ◽

Sabuj Kanti Mistry ◽

Saruna Ghimire ◽

Krishna Kumar Yadav ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Older Adults ◽

Cross Sectional Study ◽

Rural Setting ◽

Ageing Population ◽

Sectional Study ◽

Cross Sectional ◽

Factors Associated

Background The ageing population in most low-and middle-income countries is accompanied by an increased risk of non-communicable diseases culminating in a poor quality of life (QOL). However, the factors accelerating this poor QOL have not been fully examined in Nepal. Therefore, this study examined the factors associated with the QOL of older adults residing in the rural setting of Nepal. Methods Data from a previous cross-sectional study conducted among older adults between January and April 2018 in in rural Nepal was used in this study. The analytical sample included 794 older adults aged ≥60 years, selected by a multi-stage cluster sampling approach. QOL was measured using the Older People’s Quality of Life tool; dichotomized as poor and good QOL. Other measures used included age, gender, ethnicity, religion, marital status, physical activity, and chronic diseases such as osteoarthritis, cardiovascular disease, diabetes, chronic obstructive pulmonary disease (COPD), and depression. The factors associated with QOL were examined using mixed-effects logistic regression. Results Seven in ten respondents (70.4%) reported a poor QOL. At the bivariate level, increasing age, unemployment, intake of alcohol, lack of physical activity as well as osteoarthritis, COPD and depression were significantly associated with a lower likelihood of a good QOL. The adjusted model showed that older age (AOR = 0.50, 95% CI: 0.28–0.90), the Christian religion (AOR = 0.38, 95% CI: 0.20–0.70), and of an Indigenous (AOR: 0.25; 95% CI: 0.14–0.47), Dalit (AOR: 0.23; 95% CI: 0.10–0.56), and Madheshi (AOR: 0.29; 95% CI: 0.14–0.60) ethnic background were associated with lower odds of good QOL. However, higher income of >NRs 10,000 (AOR = 3.34, 95% CI: 1.43–3.99), daily physical activity (AOR: 3.33; 95% CI: 2.55–4.34), and the absence of osteoarthritis (AOR: 1.9; 95% CI: 1.09–3.49) and depression (AOR: 3.34; 95% CI: 2.14–5.22) were associated with higher odds of good QOL. Conclusion The findings of this study reinforce the need of improving QOL of older adults through implementing programs aimed at addressing the identified biosocial and disease conditions that catalyse poor QOL in this older population residing in rural parts of Nepal.

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Poor quality of life is associated with obesity and sedentary life style in atherosclerotic disease: a cross-sectional study / A má qualidade de vida está associada à obesidade e ao estilo de vida sedentário na doença aterosclerótica: um estudo transversal

Brazilian Journal of Health Review ◽

10.34119/bjhrv4n5-132 ◽

2021 ◽

Vol 4 (5) ◽

pp. 20118-20131

Author(s):

Elisa Maia Dos Santos ◽

Grazielle Vilas Bôas Huguenin ◽

Paulo Rogério Melo Rodrigues ◽

Bernardete Weber ◽

Annie Seixas Bello De Moreira

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Risk Factors ◽

Cross Sectional Study ◽

Poor Quality ◽

Atherosclerotic Disease ◽

Sectional Study ◽

Cross Sectional ◽

Sf 36

The Health-related quality of life (HRQoL) is an important measure of the health status of a population. It can be related to nutritional status and risk factors of cardiovascular disease.This study aimed to assess the quality of life and the association with nutritional status and other modifiable risk factors in patients with atherosclerotic disease.This is a cross-sectional study carried out in two public health centers in Rio de Janeiro, Brazil. A total of 273 participants with a documented history of atherosclerotic disease in the last ten years from their entry to the study. Quality of life (SF-36 questionnaire); physical activity; food intake (food frequency questionnaire), blood pressure; anthropometric and biochemical measures were assessed. Poor quality of life scores were identified, women had lower scores (p0.05) for all SF-36 domains. Obesity was associated with a decreased score of SF-36 physical and mental health domains. Sedentary lifestyle was associated with poorer quality of life in almost all domains assessed. The adoption of healthy weight and appropriate physical activity was associated with better quality of life in patients with atherosclerotic disease.

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