scholarly journals Lipoma of the cerebellopontine angle: case reports and literature review

1994 ◽  
Vol 52 (1) ◽  
pp. 58-63 ◽  
Author(s):  
Marcelo P. Ferreira ◽  
Nelson P. Ferreira ◽  
Rene Lenhardt

Two patients with cerebellopontine angle (CPA) lipoma were studied. They were submitted to surgical treatment. Available literature was reviewed and 29 cases with same lesion were identified which had been treated by surgery. Clinical manifestations, possibility of diagnostic methods, surgical indications and treatment strategies are discussed. Attention is called to the peculiarities of CPA lipomas and the doubtful vality of attempting complete excision in all cases.

Author(s):  
Maksim Vladimirovich Shpagin ◽  
Anton Viktorovich Yarikov ◽  
Denis Nikolaevich Nikitin ◽  
Igor Anatolievich Lobanov ◽  
Ivan Aleksandrovich Laganin ◽  
...  

The article is devoted to rare brain pathology, i.e. epidermoid cysts. The histological picture of the tumor is described; the classification is given. On the basis of our own clinical observations and a literature review, the features of the clinical manifestations of cholesteatoma of the cerebellopontine angle, modern approaches to the diagnosis and tactics of complex treatment are presented.


2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Rotem Semo Oz ◽  
Melissa S. Tesher

Abstract Background Lipopolysaccharide (LPS)-responsive and beige like anchor (LRBA) deficiency is categorized as a subtype of common variable immune deficiency (CVID). A growing number of case reports and cohorts reveal a broad spectrum of clinical manifestations and variable phenotype expression, including immune dysregulation, enteropathy and recurrent infections. The association between rheumatic disease and CVID generally has been well established, arthritis has been less frequently reported and minimal data regarding its clinical features and characteristic in LRBA deficiency has been published. This case report and literature review evaluates the characteristics and features of arthritis in LRBA deficiency patients. Case presentation and review results Herein, we describe a unique case of LRBA deficiency first presented with poly articular arthritis. Alongside the report, a literature review focusing on LRBA deficiency, rheumatic disease and arthritis has been conducted. We reviewed 43 publications. Among these, 7 patients were identified with arthritis. Age of first presentation was six weeks to 3 years. Male to female ratio was 4/3. Two patients were diagnosed with polyarticular Juvenile idiopathic arthritis (JIA) and three with oligoarticular JIA. Each patient was found to have different genomic mutation. The treatment was diverse and included corticosteroids, cyclosporine, methotrexate, adalidumab and abatacept. Conclusion Joint involvement is variable in LRBA deficiency, hence it should always be kept in mind as a differential diagnosis for a patient with combination of juvenile arthritis and clinically atypical immune dysregulation and / or immunodeficiency.


2020 ◽  
pp. 014556132093492
Author(s):  
Dmitry Tretiakow ◽  
Andrzej Skorek

Salivary lymphoepithelial carcinoma is a highly radiosensitive tumor that suggests the effectiveness of induction chemotherapy and induction concurrent chemoradiotherapy without previous surgery. However, the imperfection of diagnostic methods and the severe consequences of misdiagnosis of the tumor do not allow to resign from surgical treatment in patients with this type of salivary gland tumor.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Emilija Jonaitytė ◽  
Martynas Judickas ◽  
Eglė Tamulevičienė ◽  
Milda Šeškutė

Alveolar echinococcosis (AE) is an infectious zoonotic disease that is caused by Echinococcus multilocularis. The disease is generally identified accidentally because of the long asymptomatic period, has a malignant behaviour, and mainly occurs in the liver. Usually it is diagnosed in adults and is very rare in pediatric patients. We report two cases of AE and 1 differential case between AE and cystic echinococcosis (CE) in children: two of them had lesions in the liver and one had rare extrahepatic presentation of a cyst in the spleen. All our patients received chemotherapy with albendazole because surgical treatment was not recommended. The children were followed-up from 10 to 30 months and no significant improvement was seen. In this report we discuss the difficulties we faced in the treatment and follow-up of these patients. We also review the main clinical manifestations, general diagnostic methods, and treatment options of AE according to the current literature.


2019 ◽  
Vol 10 (1) ◽  
pp. 89-101 ◽  
Author(s):  
Samuel Tawfik ◽  
Kevin Phan ◽  
Ralph J. Mobbs ◽  
Prashanth J. Rao

Study Design: Literature review. Objective: To conduct a literature review of studies reporting the incidence of pars interarticularis defects in athletes of specific sports, in order to allow more targeted prevention and treatment strategies to be implemented for the groups at highest risk. Methods: Electronic searches were performed using PubMed, Ovid Medline, EMBASE, Google Scholar, Cochrane Database of Systematic Reviews, and Cochrane Database of Controlled Trials from their dates of inception to September 2017, with the following keywords: “spondylolysis,” “sports,” “low back pain,” and “pars defects.” Results: A total of 509 total articles were retrieved, of which 114 were used in the final review. The incidence of pars interarticularis defects was found to be highest in diving (35.38%), cricket (31.97%), baseball/softball (26.91%), rugby (22.22%), weightlifting (19.49%), sailing (17.18%), table tennis (15.63%), and wrestling (14.74%). Only 5 studies reported the management instituted for their participants, and these were all case reports. Of 74 players with spondylolysis in these studies, 70 (94.59%) underwent conservative treatment and 4 (5.41%) underwent surgical treatment. 61 (82.43%) returned to their previous level of play, 6 (8.11%) retired, and the disposition of the final 7 was not reported. Conclusion: The current medical literature provides good evidence that the incidence of pars interarticularis defects is higher in the athletic population, with the highest incidence in diving. There remains no gold standard protocol for the management of pars interarticularis defects. Further research is required to compare conservative therapy to surgical therapy and to compare the various surgical techniques to each other.


2020 ◽  
Vol 10 (3) ◽  
pp. 339-352
Author(s):  
Svetlana V. Sergeeva

Introduction. An assessment of the effectiveness of antenatal diagnosis and postnatal management of infants and infants with grade IV hydronephrosis was performed based on the analysis of domestic and foreign literature. Literature review. In the literature analysis, we used the databases СlinicalKey, Web of Science, Cyberleninka, PubMed, and Medline. The search was not limited by the publication date; instead, the searchs emphasis was placed on publications of the last 10 years. Classification. Several classification systems have been developed to assess the severity of hydronephrosis in infants. However, none of them describes the degree of expansion of the PCS and the functional state of the renal parenchyma. This work shows the stages of embryogenesis of the obstruction of the pyelourethral segment. Diagnosis. The issues of antenatal diagnostics and prognostically significant outcome criteria for an intrauterine malformation of the fetal urinary system are considered. The main diagnostic methods in the postnatal period are described. Morphological changes. Variants of pathomorphological changes in the renal parenchyma, the pelvic wall, and ureter in prolonged obstruction conditions are described. The role and variability of the number of Cajal interstitial cells in the pelvic wall and ureter in hydronephrosis have been analyzed. Treatment. Particular attention is paid to nephroprotective therapy and surgical treatment tactics of the defect. Questions regarding the timing and choice of treatment methods, the need and duration of preliminary urine diversion in infants and children with grade IV hydronephrosis remain open. Conclusion. Analysis of the world literature shows that there is no single protocol for intrauterine diagnosis and postnatal management of children with grade IV hydronephrosis. The functional state of the parenchyma is possible only with a comprehensive examination to assess the degree of hydronephrosis. Improving antenatal and postnatal diagnostics, therapeutic and surgical treatment of children with severe hydronephrosis should be based on a doctors cooperation, a specialist in ultrasound diagnostics, a nephrologist, and a pediatric surgeon.


e-GIGI ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 256
Author(s):  
Yobel R. Woran ◽  
Lydia E. N. Tendean ◽  
Christy N. Mintjelungan

Abstract: The COVID-19 outbreak is caused by SARS-CoV-2 that spread rapidly throughout the world. The most common clinical manifestations of COVID-19 are fever, fatigue, and dry cough. Some patients experience nasal congestion, runny nose, headache, conjunctivitis, sore throat, diarrhea, skin rash, loss of smell and taste. Oral manifestations of COVID-19 infection are also reported. Dentists are prone to cross-infections of several infectious diseases because they are often exposed to saliva and blood. These viruses are transmitted through inhalation of aerosols and droplets containing the viruses or direct contact with mucous membranes, oral fluids, dental instruments, and surfaces contaminated with the virus. This study was aimed to determine the oral manifestations of COVID-19 infection. This was a literature review study searching three databases, namely Pubmed, ClinicalKey and Google Scholar. The keywords used were oral AND manifestations AND COVID-19. Selection based on inclusion and exclusion criteria was carried out by critical appraisal. There were eight literatures in the form of case reports. The results showed that oral manifestations commonly found in patients with clinical COVID-19 were ulcers, petechiae, macules, and plaques with variations in quantity, color appearance, and localization. Lesions were found on the palate, tongue, labial mucosa, gingiva, lips, and oropharynx. In conclusion, oral manifestations could be found in clinical COVID-19 patients, however, it is not certain whether these manifestations are directly caused by SARS-CoV-2 or are as secondary manifestations.Keywords: oral manifestations; COVID-19 Abstrak: Wabah COVID-19 disebabkan oleh SARS-CoV-2 yang menyebar dengan cepat hingga ke seluruh dunia. Infeksi COVID-19 mempunyai manifestasi klinis paling umum seperti demam, rasa lelah, dan batuk kering. Beberapa pasien mengalami hidung tersumbat, pilek, nyeri kepala, konjungtivitis, sakit tenggorokan, diare, ruam kulit, hilang penciuman dan pengecapan. Bahkan terdapat laporan penemuan manifestasi oral pada infeksi COVID-19. Dokter gigi sebagai profesi yang rentan terjadi infeksi silang beberapa penyakit menular karena sering terpapar dengan saliva dan darah. Virus ini memungkinkan terjadinya penularan lewat terhirupnya aerosol dan droplet yang mengandung virus atau kontak langsung dengan membran mukosa, cairan mulut, instrumen kedokteran gigi dan permukaan yang terkontaminasi virus. Penelitian ini bertujuan untuk mengetahui manifestasi oral infeksi COVID-19. Jenis penelitian ialah suatu literature review dengan pencarian menggunakan tiga database yaitu Pubmed, ClinicalKey dan Google Scholar. Kata kunci yang digunakan yaitu oral AND manifestations AND COVID-19. Setelah seleksi berdasarkan kriteria inklusi dan ekslusi dilakukan critical appraisal dan didapatkan delapan literatur yang berupa laporan kasus.Hasil penelitian mendapatkan bahwa manifestasi oral pada pasien klinis COVID-19 yang sering ditemukan, seperti ulkus, petekie, makula, dan plak dengan variasi kuantitas, penampakan warna, dan lokalisasi. Lokasi lesi ditemukan pada palatum, lidah, mukosa labial, gingiva, bibir dan orofaring. Simpulan penelitian ini ialah manifestasi oral dapat ditemukan pada pasien klinis COVID-19 tetapi belum diketahui pasti apakah secara langsung disebabkan oleh SARS-CoV-2 atau merupakan manifestasi sekunder.Kata kunci: manifestasi oral; COVID-19


e-CliniC ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Amalita Mannana ◽  
Stephanus J. Ch. Tangel ◽  
Eko Prasetyo

Abstract: Peritonitis is defined as inflammation of serosal membrane that lines the abdominal cavity (peritoneum) and the organs contained therein. Secondary peritonitis accounts for 1% of urgent emergent hospital admidssions and is the second leading cause of sepsis in patients in intensive care units globally. Despite the growth in the availability of imaging and laboratory test, the rapid diagnosis of peritonitis remains a challenge for physicians in emergency medicine, surgery, and critical care. This study was aimed to obtain the rapid and appropriate diagnostic methods of secondary peritonitis. This was a literature review study using databases of PubMed, ClinicalKey, and Google Scholar on topics related to the diagnosis of secondary peritonitis. The results showed that there were 12 literatures in this study consisting of 5 review articles, 1 literature review, and 6 prospective studies. The literatures reviewed the diagnosis of secondary peritonitis based on clinical manifestations, physical examination, and the other examinations including laboratory examination, abdominal ultrasound, and abdominal CT scan. In conclusion, the diagnosis of secondary peritonitis is based on clinical manifestation including abdominal pain, rigidity, and rebound tenderness. These sign and symptoms may be supported by laboratory and radiology findings as additional tests if needed. Abdominal ultrasonography is the most practical and non-invasive radiology test for rapid diagnostic in a subgroup of patients with secondary peritonitis whose clinical impression is unclear.                            Keywords: Secondary Peritonitis, Diagnosis of Secondary Peritonitis, Acute Abdomen Abstrak: Peritonitis adalah inflamasi pada selaput serosa yang membungkus rongga abdomen (peritoneum) dan organ yang terkandung di dalamnya. Peritonitis sekunder menyumbang 1% insiden pada pasien yang masuk di UGD dan merupakan penyebab utama kedua terjadinya sepsis pada pasien di ICU secara global. Di tengah perkembangan ketersediaan pemeriksaan radiologi dan laboratorium yang pesat, diagnosis yang cepat pada peritonitis masih menjadi tantangan bagi para dokter dalam penanganan darurat, pembedahan, dan perawatan pasien kritis. Penelitian ini bertujuan untuk mengetahui metode diagnosis yang cepat dan tepat pada peritonitis sekunder. Jenis penelitian ialah literature review menggunakan database PubMed, ClinicalKey, dan Google Scholar. Hasil penelitian mendapatkan 12 literatur terdiri dari 5 review article, 1 literature review, dan 6 prospective study yang mengulas tentang diagnosis peritonitis sekunder ditegakkan berdasarkan manifestasi klinis, pemeriksaan fisik, dan berbagai pemeriksaan penunjang lainnya yang mencakup pemeriksaan laboratorium, USG abdomen, dan CT scan abdomen. Simpulan penelitian ini ialah diagnosis peritonitis sekunder ditegakkan berdasarkan manifestasi klinis seperti nyeri abdomen, rigiditas, dan rebound tenderness. Tanda dan gejala ini dapat didukung oleh temuan radiologi dan laboratorium sebagai pemeriksaan tambahan bila diperlukan. USG abdomen merupakan pemeriksaan radiologi yang paling praktis dan non-invasif untuk diagnosis cepat pada kelompok pasien peritonitis sekunder dengan kesan klinis yang tidak jelas.Kata kunci: peritonitis sekunder, diagnosis peritonitis sekunder, akut abdomen


Author(s):  
Max J. Scheyerer ◽  
Christian Herren ◽  
Christian Kühne ◽  
Jörg Neufang ◽  
Philipp Pieroh ◽  
...  

Abstract Background Despite advances, the morbidity and mortality rates of patients with spondylodiscitis remains high, with an increasing incidence worldwide. Although conservative therapy has progressed, several cases require surgical intervention. However, the indication and opportunities for surgical treatment are still disputable. Methods In a joint consensus, the members of the ‘Spondylodiscitis’ working group of the Spine Section of the German Society for Orthopaedics and Trauma Surgery considered current literature, particularly the newly published S2k guideline of the AWMF, and examined the surgical indications and treatment strategies for thoracolumbar spondylodiscitis. Results Surgical intervention for spondylodiscitis is only required in a small percentage of patients. In studies comparing conservative and surgical therapies, most patients benefitted from surgery, regardless of the surgical technique selected. Presently, the standard procedure is a combined dorsoventral approach, in which a monolateral attempt should always be made. The choice of material (PEEK, titanium) for ventral support does not influence the clinical result.


2019 ◽  
Vol 24 (4) ◽  
Author(s):  
Maciej Adam Chęciński ◽  
Aleksandra Rubinkiewicz ◽  
Kamila Chęcińska

The mandibular mesiodens is an anomaly consisting in the occurrence of a supernumerary tooth in the described area. The few described cases of this pathology are summarized in this article. The literature review was conducted using the PubMed and Google Scholar databases, using two sets of keywords each time. Further analysis of the collected articles allowed inclusion of case reports from the last two decades in the review. 18 cases of the occurrence of the medial tooth of the mandible were compared. The possible aetiology of this developmental anomaly could not be determined. The most likely pathogenesis is the hyperactivity of the dental lamina. Among the diagnostic methods, the sumative and three-dimensional imaging methods play an important role. Depending on the case, two various treatment methods are undertaken: surgical, meaning removal of the supernumerary tooth or conservative, consisting in correction of its shape. The prognosis using both methods is good. Mandibular mesiodens is extremely rare, with similar frequency in both genders, and its occurrence often coexists with the agenesis of other mandibular teeth. Both extraction and conservative treatment have a good therapeutic effect.


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