scholarly journals Epidemiologic study of bronchopulmonary mycosis in the province of cordoba, argentina

1987 ◽  
Vol 29 (1) ◽  
pp. 59-62 ◽  
Author(s):  
Diana T. Masih ◽  
Blanca E. marticorena ◽  
Noemi Borletto ◽  
Camilo Farías ◽  
Ricardo Negroni
Keyword(s):  
Epidemiological Study ◽  
Epidemiologic Study ◽  
Skin Tests ◽  
Positive Skin ◽  
Very High ◽  
Made In

An epidemiological study for histoplasmosis coccidioidomycosis and cryptococcosis made in five areas of the province of Córdoba is presented. The data obtained showed a global positivity of 41.1% for histoplasmin 26.7% for coccidioidin and 14.1% for cryptococcin. In some areas, the Rio III basin and Traslasierra, the histoplasmosis infection indexes were much higher, 53,3% and 73.1% respectively. The index of positive skin tests with Cryptococcus antigen in Traslasierra was also very high: 31.9%.

Exercise-Induced Bronchial Lability in Wheezy Children and Their Families

PEDIATRICS ◽  
1975 ◽  
Vol 56 (5s) ◽  
pp. 851-855
Author(s):  
Simon Godfrey ◽  
Peter König
Keyword(s):  
Genetic Basis ◽  
Skin Tests ◽  
Exercise Tests ◽  
Positive Skin ◽  
Asthmatic Children ◽  
High Incidence ◽  
The Difference ◽  
Exercise Induced ◽  
Very High ◽  
Similar Incidence

Studies have been carried out to investigate bronchial lability as assessed by means of standardized running exercise tests. It was found that children who had been wheezy as infants still had an abnormal degree of bronchial lability, even if they were asymptomatic, and closely resembled children who had continued to wheeze. The relatives of asthmatic children displayed a high incidence of bronchial lability. atopic diseases, and positive skin tests, and a similar incidence was found in the relatives of babies with wheezy bronchitis. The difference from a control population was particularly noticeable in the healthy relatives of wheezy children. Studies in monozygotic and dizygotic twins have shown a very high incidence of concordance for asthma, particularly when bronchial lability is taken into account. These studies suggest a common genetic basis for wheezing in childhood, based on the inheritance of bronchial lability. The difference in response of the actively asthmatic subject from that of other labile subjects suggests that additional environmental factors are necessary to interact with the inherited bronchial lability.

Comparative Assessment of Platinum Salts and Taxane Group Hypersensitivity Reactions, The Role of Skin Tests in Diagnosis?

2021 ◽  
pp. 107815522110500
Author(s):  
Kadriye Terzioğlu ◽  
Murat Ayhan
Keyword(s):  
Skin Test ◽  
Skin Tests ◽  
Hypersensitivity Reactions ◽  
Positive Skin ◽  
Suspect Drug ◽  
Platinum Salts ◽  
Grade 3 ◽  
Pain Symptoms ◽  
Very High

Purpose We aimed to investigate the role of skin tests (ST) in the diagnosis of hypersensitivity reactions (HSRs) with platinum salts (PS) and taxane (TX) groups drugs and their reliability in patient management. Materials and Method Patients' data who developed immediate HSR with PS and TX were recorded and ST was performed. The gradual challenge was applied to all patients with ST negative and grade 1–2 with the suspect drug. Results In total, the data of 104 patients (74 with PS, 30 with TX) who developed HSR against PS and TX were shared. The gradual challenge was applied to 72 ST negative and grade 1–2 patients (46 PS group, 26 TX group). The gradual challenge was negative in 39 patients in the PS group and 23 patients in the Tx group. The negative predictive value (NPV) for PS was 83% and NPV for TX was 88%. We found significantly higher skin test positivity in patients with PS and TX and grade 3 HSR ( p = 0.007, p = 0.001). A significant correlation was found between skin test positivity and early onset of symptoms ( p = 0.001 for PS, p = 0.015 for TX). In terms of symptoms witnessed in HSR, we observed the itching, urticaria, hypotension, syncope, and abdominal pain symptoms significantly more in the group with a positive skin test ( p < 0.024, p < 0.001, p < 0.001, p < 0.002, and p < 0.025, respectively). Conclusions We found very high NPV values for PS and TX. We found that the gradual challenge applied to patients with negative skin tests is reliable if Grade 3 HSR is not observed and with this approach, unnecessary desensitization processes and/or drug alterations can be avoided.

Data Management in an Epidemiological Study : Experiences from the Iowa 500 Field Follow-up and Family Study

1980 ◽  
Vol 19 (01) ◽  
pp. 37-41
Author(s):  
R. F. Woolson ◽  
M. T. Tsuang ◽  
L. R. Urban
Keyword(s):  
Data Management ◽  
Epidemiological Study ◽  
Family Study ◽  
Data Sets ◽  
Data Handling ◽  
Management Decisions ◽  
Numerous Data ◽  
Made In

We are now conducting a forty-year follow-up and family study of 200 schizophrenics, 325 manic-depressives and 160 surgical controls. This study began in 1973 and has continued to the present date. Numerous data handling and data management decisions were made in the course of collecting the data for the project. In this report some of the practical difficulties in the data handling and computer management of such large and bulky data sets are enumerated.

FUNGI IN AIR MASSES OVER MONTREAL DURING 1950 AND 1951

1956 ◽  
Vol 34 (1) ◽  
pp. 1-15 ◽  
Author(s):  
S. M. Pady ◽  
L. Kapica
Keyword(s):  
Seasonal Variation ◽  
Pollen Grains ◽  
Average Concentration ◽  
Yeast Cells ◽  
The Sun ◽  
Air Masses ◽  
Air Sampler ◽  
Agricultural Areas ◽  
Very High ◽  
Made In

Numbers and kinds of fungi were determined from nutrient plate and silicone slide studies from the roof of the Sun Life Building, Montreal, between September 1950 and December 1951. Exposures of plates were made in the General Electric Bacterial Air Sampler, and plates and silicone slides in the Bourdillon Slit Sampler. A total of 978 exposures was made on 113 sampling days during 16 months; 507 plates in the G. E. Sampler, 344 plates and 127 slides in the Slit Sampler. Of 40,359 colonies examined, Cladosporium, Penicillium, yeasts, Aspergillus, Alternaria, and Actinomycetes were commonest, constituting 47.7, 15.8, 10.4, 4.6, 4.2, and 2.2% of the total. The next commonest fungi were Pullularia, Oöspora, Fusarium, Stemphylium, Verticillium, Rhizopus, Spicaria, Scopulariopsis, Phoma, Mucor, Botrytis, Cephalosporium, Trichoderma, Helmin-thosporium, Neurospora, Papularia, Cephalothecium, Pyrenochaeta, Zythia, and Nigrospora. In addition 12 genera were infrequently found. Unidentified colonies numbered 174 and nonsporulating 3371 (8.3%). On a cubic foot basis numbers in the plates varied from 17.7 per cu. ft. in August to 0.4 per cu. ft in February.Fungus spores showed a seasonal variation with summer highs averaging 244 per cu. ft. in July to a low of 0.8 per cu. ft. in December. The most abundant spores were Cladosporium, yeasts, smuts, Fusarium, Alternaria, Venturia-like, Stemphylium, rusts, Septoria, and Helminthosporium. Hyphal fragments and pollen grains were present also. On eight occasions during the summer, readings of over 200 spores per cu. ft. were recorded, the maximum being 445 per cu. ft. on September 6, 1951. Cladosporium in August reached a peak of 74.1 per cu. ft. and yeast cells in July had an average concentration of 100 per cu. ft.An analysis of the air masses indicated that pure polar air carried low numbers of fungi, whereas tropical air had very high numbers. Most of the air masses were modified polar air and their fungus content varied considerably. The fungi in the air over Montreal are believed to have had their origin in agricultural areas.

Flow Field on Helodeck of a Frigate: A Review

2019 ◽  
Vol 161 (A4) ◽  
Keyword(s):  
Flow Field ◽  
Numerical Solutions ◽  
Offshore Structures ◽  
High Speeds ◽  
High Turbulence ◽  
The Subject ◽  
Offshore Industry ◽  
The Military ◽  
Very High ◽  
Made In

The various functions desired from a frontline warship such as a frigate, corvette or a destroyer, coupled with the requirement of very high speeds and economic viability restricting the size, necessitates a very dense arrangement of weapons and sensors on the top deck and superstructure. Accordingly, Navies across the world have faced several problems with respect to functions for which a good aerodynamic design for these structures is essential. Major issues include smoke nuisance created due to impinging of the ship's exhaust gases on to the top deck leading to possible suction by engine intakes and high turbulence in the ship's air-wake leading to ship aircraft interface concerns. The flow field on the helodeck is extremely complex due to its geometry and interaction with the wake of the ship’s superstructure. A knowledge of this complexity is essential for ensuring safe helo operations on the helodeck. The problem of ship helicopter interaction has hogged the lime light in recent times, due to rising demand for design of warships for increased stealth, especially in the past two decades. Consequently, several researchers in countries with advanced Navies have invested considerable resources towards evolving both experimental and numerical solutions for the problem. However, given the military nature of the operations, open literature on the subject containing details of such research, which can be used as reference material for present work, are limited. Considering the complexities involved in the problem, an attempt has been made in this paper to holistically review the widely scattered and limited literature in this field. A good amount of literature on marine helo applications emerge from the offshore industry. Keeping in mind that the fields of warship design and offshore structures are dissimilar and have their peculiar problems, informed conclusions have been made in drawing lessons from available literature.

Penicillin Hypersensitivity

1979 ◽  
Vol 1 (5) ◽  
pp. 132-158
Keyword(s):  
Skin Test ◽  
Multicenter Study ◽  
Positive Skin Test ◽  
Penicillin Allergy ◽  
Skin Tests ◽  
Penicillin G ◽  
Positive Skin ◽  
Positive History ◽  
History Of

A (massive) multicenter study of 3,000 patients has demonstrated that skin tests to penicillin G and penicilloyl-polylysine (PPL-now commercially available) predict and confirm penicillin allergy. Of patients with a history of penicillin reaction, 19% were positive to either, compared to 7% of controls. A history of anaphylaxis led to 46% positive. Of those with a history of urticaria 17% were positive, and those with maculopapular eruptions did not differ from controls (7% positive). Challenge with penicillin led to a reaction in 6% with a positive history (compared to 2% with a negative) and 67% with a combined positive history and positive skin test (to either).

scholarly journals Moving Forward With Accelerometer-Assessed Physical Activity: Two Strategies to Ensure Meaningful, Interpretable, and Comparable Measures

2018 ◽  
Vol 30 (4) ◽  
pp. 450-456 ◽  
Author(s):  
Alex V. Rowlands
Keyword(s):  
Physical Activity ◽  
Black Box ◽  
Data Sets ◽  
Accelerometer Data ◽  
Future Health ◽  
The Past ◽  
Acceleration Data ◽  
Night And Day ◽  
Very High ◽  
Made In

Significant advances have been made in the measurement of physical activity in youth over the past decade. Monitors and protocols promote very high compliance, both night and day, and raw measures are available rather than “black box” counts. Consequently, many surveys and studies worldwide now assess children’s physical behaviors (physical activity, sedentary behavior, and sleep) objectively 24 hours a day, 7 days a week using accelerometers. The availability of raw acceleration data in many of these studies is both an opportunity and a challenge. The richness of the data lends itself to the continued development of innovative metrics, whereas the removal of proprietary outcomes offers considerable potential for comparability between data sets and harmonizing data. Using comparable physical activity outcomes could lead to improved precision and generalizability of recommendations for children’s present and future health. The author will discuss 2 strategies that he believes may help ensure comparability between studies and maximize the potential for data harmonization, thereby helping to capitalize on the growing body of accelerometer data describing children’s physical behaviors.

Meglumine antimoniate-induced DRESS: original case with a positive skin test

2018 ◽  
Vol 63 (4) ◽  
pp. 845-847 ◽  
Author(s):  
Amel Chaabane ◽  
Haifa Ben Romdhane ◽  
Hajer Ben Brahim ◽  
Nadia Ben Fredj ◽  
Zohra Chadli ◽  
...  
Keyword(s):  
Skin Test ◽  
Clinical Picture ◽  
Drug Withdrawal ◽  
Skin Tests ◽  
Positive Skin ◽  
Meglumine Antimoniate ◽  
Blood Tests ◽  
Intradermal Tests ◽  
Original Case ◽  
Hepatic Cytolysis

Abstract We report a case of a 64-year-old woman treated with meglumine antimoniate (Glucantime®). On day 20, she developed fever, a pruriginous skin rash and myalgia. The blood tests showed eosinophilia and hepatic cytolysis. The clinico-biological picture improved gradually and the symptoms disappeared 4 weeks after the drug withdrawal. Six weeks later, intradermal tests to Glucantime® were performed and were positive at 48 hour-reading. This clinical picture suggests DRESS induced by meglumine antimoniate. To the best of our knowledge, only one case of meglumine antimoniate-induced DRESS has been reported in the literature and we are the first to report a case confirmed by skin tests.

scholarly journals Allergy to cephalosporin antibiotics in children

2003 ◽  
Vol 131 (3-4) ◽  
pp. 127-130 ◽  
Author(s):  
Marina Atanaskovic-Markovic ◽  
Branimir Nestorovic
Keyword(s):  
Allergic Reaction ◽  
Cross Reactivity ◽  
Skin Tests ◽  
Allergic Reactions ◽  
First Line ◽  
Positive Skin ◽  
Cephalosporin Antibiotics ◽  
The Cross ◽  
Single Blind ◽  
Common Infections

A particular problem is the safety of administering cephalosporins to penicillin-allergic children, because cephalosporin allergenic determinants have not been properly identified. Cephalosporin antibiotics are widely used to treat common infections and are often the first-line prophylaxis before many types of surgery. So the arm of this study is to determine the frequency of allergic reactions of anaphylactic type to cephalosporins and their cross-reactivity with penicillins. At University Children?s Hospital in Belgrade a group of 1,170 children with suspected anaphylactic allergic reaction to penicillins and/or cephalosporins were tested for the last eight years. Skin tests were performed with standard concentration of penicillins and cephalosporins. In children where skin tests were negative single-blind placebo-controlled challenges were performed. In case of positive skin tests further examinations were interrupted and the children were considered allergic to that drug. The frequency of anaphylactic allergic reactions to cephalosporins is 0.2 % to 17 %, and depends on cephalosporins generation. The cross-reactivity between cephalosporins and penicillins is 0.1 % to 14.5 %, and among cephalosporins is 0 % to 11.7 %.

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