Effect of home-based exercise program on lymphedema and quality of life in female postmastectomy patients: Pre-post intervention study

Introduction: Head and neck cancer patients often suffer from physical and cognitive impairments after cancer treatment. During rehabilitation, exercise therapy can improve physical function and quality of life (QoL). Surveys demonstrated patients’ preference for home training with low- to moderate-intensity. This study was conducted in order to develope a suitable home-based training program. Therefore, the feasibility and effects of a low- to moderate-intensity exercise intervention on physical functions and QoL were evaluated. Methods: Training was conducted as supervised group training and consisted of mobilization, coordination, resistance, stretching, and relaxation exercises. The intervention lasted 12 weeks with 2 training sessions per week. Feasibility, attendance rate, physical function (eg, range of motion, 6-minute walk test [6MWT]), and QoL (eg, EORTC QLQ-30) were analyzed. Results: Ten out of 12 participants completed the intervention (83%) with an average attendance rate of 83%. Participants showed significant improvements in selected physical functions. For example, head rotation increased by 11.2° ( P = .042), walking distance in the 6MWT increased by an average of 43.3 m ( P = .010), and the global QoL scale improved by 8.2 points ( P = .059). Additionally, there were positive changes in the physical function scale ( P = .008), cognitive function scale ( P = .015), and social function scale ( P = .031) of the EORTC QLQ-30. Conclusion: Data indicate that the exercise program was feasible and had positive effects on physical function and QoL. Future research will analyze the effects of a home-based exercise program on physical function and QoL in a large-scale study.

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Effects of modest testosterone supplementation and exercise for 12 weeks on body composition and quality of life in elderly men

Acta Endocrinologica ◽

10.1530/eje.1.02291 ◽

2006 ◽

Vol 155 (6) ◽

pp. 867-875 ◽

Cited By ~ 37

Author(s):

Laurence Katznelson ◽

Mara W Robinson ◽

Caryn L Coyle ◽

Hang Lee ◽

Christina E Farrell

Keyword(s):

Quality Of Life ◽

Body Composition ◽

Resistance Exercise ◽

Exercise Program ◽

Serum Testosterone ◽

Exercise Group ◽

Community Dwelling ◽

Elderly Men ◽

Home Based

Objective: One of the factors that may promote deterioration in quality of life and body composition in elderly men is the relative decline in serum testosterone levels with aging. In this study, we assessed the effects of modest doses of testosterone and a home-based strengthening program on quality of life and body composition in elderly men with relative testosterone insufficiency. Design: Double-blind, placebo-controlled randomized study (testosterone), and additional randomization to a resistance exercise program or no additional exercise for 12 weeks in men between ages of 65 and 85 years with relative testosterone insufficiency. Methods: Seventy sedentary, community dwelling men were randomized to a 5 mg testoderm transdermal system applied daily vs placebo system, and additionally randomized to a home-based resistance exercise program. Subjects were randomized to Group 1 (testosterone plus exercise), Group 2 (testosterone plus no exercise), Group 3 (placebo plus exercise), and Group 4 (placebo plus no exercise). Endpoints included quality of life (assessed by the short form-36 questionnaire) and body composition (measured by dual x-ray absorptiometry scan). Results: Serum testosterone increased by a mean of 10.0 ± 1.9, 6.6 ± 1.6, 0.52 ± 0.6, and 0.5 ± 0.6 nmol/l in Groups 1, 2, 3, and 4 respectively. There was a significant interaction of testosterone and exercise on quality of life in the domains of physical functioning (P = 0.03), role physical (P = 0.01), general health (P = 0.049), and social functioning (P = 0.04). There were no effects of testosterone or exercise on quality of life alone, nor in body composition parameters. Conclusions: Modest testosterone supplementation to elderly men with relative testosterone insufficiency improved quality of life when accompanied by an exercise program. The combination of testosterone and exercise may be an important strategy in the elderly, though further studies are necessary to determine the long-term impact on body composition and function and for analysis of risk/benefit ratios as well.

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Effects of a 12-week home-based exercise program on quality of life, psychological health, and the level of physical activity in colorectal cancer survivors.

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.9630 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 9630-9630

Author(s):

Ji Young Kim ◽

MI KYUNG LEE ◽

Ji-Hee Min ◽

Dong Hoon Lee ◽

Sunghyun Hong ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Colorectal Cancer ◽

Cancer Survivors ◽

Psychological Health ◽

Exercise Program ◽

Colorectal Cancer Survivors ◽

Home Based

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Effects of a home-based exercise program on quality of life, fatigue, and depression in patients with ankylosing spondylitis

Rheumatology International ◽

10.1007/s00296-008-0756-8 ◽

2008 ◽

Vol 29 (6) ◽

pp. 673-677 ◽

Cited By ~ 47

Author(s):

Dilek Durmus ◽

Gamze Alayli ◽

Erhan Cil ◽

Ferhan Canturk

Keyword(s):

Quality Of Life ◽

Ankylosing Spondylitis ◽

Exercise Program ◽

Home Based

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Effects of clown activities on patients eligible for palliative care in primary health care

Revista Brasileira de Enfermagem ◽

10.1590/0034-7167-2020-0431 ◽

2021 ◽

Vol 74 (5) ◽

Author(s):

Fernando Ribeiro dos Santos ◽

Sandra Pinto ◽

Juliana Dias Reis Pessalacia ◽

Bruna Moretti Luchesi ◽

Lucimeire Aparecida da Silva ◽

...

Keyword(s):

Quality Of Life ◽

Social Support ◽

Health Care ◽

Palliative Care ◽

Primary Health Care ◽

Post Intervention ◽

Primary Health ◽

Home Based ◽

Quasi Experimental

ABSTRACT Objective: Evaluate the effects of clown activities on quality of life, depression, stress, anxiety, aid, and social support in patients eligible for palliative care (PC) attended in Primary Health Care (PHC). Method: A quasi-experimental study, with pre-intervention and post-intervention evaluation, carried out with 16 patients eligible for early PC in PHC in a Midwestern city. Patients received 24 visits with home-based clown activities. Results: The interventions evidenced improved quality of life and social support, with significant results for the Social Activities dimension (p = 0.023). Increased scores for Anxiety (p = 0.007) and Depression (p = 0.023) were also observed. Conclusion: Clown activities can bring positive results for the quality of life and social support of patients eligible for PC at home. They should be encouraged to interact with family knowledge and enhance humanized care, integral and centered on human relationships in PHC.

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Exercise Management Using a Mobile App in Patients with Parkinsonism: A Prospective, Open-label, Single-arm, Pilot Study (Preprint)

10.2196/preprints.27662 ◽

2021 ◽

Author(s):

Aram Kim ◽

Seo Jung Yun ◽

Kwan Sik Sung ◽

Yeonju Kim ◽

Ju Young Jo ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Pilot Study ◽

Management Strategy ◽

Exercise Program ◽

Mobile App ◽

Open Label ◽

Home Based ◽

Secondary Outcomes

BACKGROUND Although exercise has benefits for motor function and quality of life in patients with parkinsonism, these patients have many barriers to exercise participation. Recently, the use of mobile apps has been highlighted as a remotely supervised exercise management strategy. OBJECTIVE This study aimed to evaluate the effects of home-based exercise management with a customized mobile app on exercise amount, physical activity, and quality of life in patients with parkinsonism. METHODS This was a prospective, open-label, single-arm, pilot study. Participants were encouraged to engage in an 8-week home-based exercise program delivered through a customized app. The primary outcome was the exercise amount. The secondary outcomes were International Physical Activity Questionnaire (IPAQ), Parkinson’s Disease Questionnaire-39 (PDQ-39), and Geriatric Depression Scale (GDS). RESULTS A total of 21 participants completed the intervention and assessment (mean age: 72 years; women: 17/21, 81%; men: 4/21, 19%). The participants reported a significant increase in the total amount of exercise (baseline: 343.33±206.70 min/week; 8-week follow up: 693.10±373.45 min/week; P<.001) and in the amount of each exercise component including stretching, strengthening, balance and cooperation, and oral-motor and vocal exercise after 8 weeks. The analysis of secondary outcomes revealed significant improvements in the IPAQ (P=.006), PDQ-39 (P=.02), and GDS (P=.04) scores. The usability of the program with the mobile app was verified based on the positive responses such as “intention to use” and “role expectation for rehabilitation.” CONCLUSIONS Exercise management with a customized mobile app may have benefits for improving exercise adherence, physical activity, depression, and quality of life in patients with parkinsonism. This supervised home-based, technology-based, reinforcing, and multimodal exercise management strategy should be recommend to patients with parkinsonism. In addition, this program may be useful as an alternative exercise management strategy during the COVID-19 pandemic. Additional clinical trials are needed to evaluate the efficacy of this exercise program in a large population and to confirm its disease-modifying effects.

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Effect of a Home Exercise Program Based on Tai Chi in Patients with End-Stage Renal Disease

Peritoneal Dialysis International ◽

10.1177/089686080302302s21 ◽

2003 ◽

Vol 23 (2_suppl) ◽

pp. 99-103 ◽

Cited By ~ 15

Author(s):

Kin-wa Ling ◽

Flora S.Y. Wong ◽

Wing-ki Chan ◽

Shuk-yin Chan ◽

Eric P. Y. Chan ◽

...

Keyword(s):

Quality Of Life ◽

Kidney Disease ◽

End Stage Renal Disease ◽

Exercise Program ◽

Well Being ◽

Home Based ◽

Stage Renal Disease ◽

End Stage ◽

Minute Walk

Objective Previous reports have documented the benefits of exercise on the well-being of renal patients. However, fewer than 50% of our end-stage renal disease (ESRD) patients engage in regular exercise. To promote exercise, we implemented a home-based exercise program. The aim of the program was to reduce barriers to exercise by helping patients to exercise at their convenience and without the need to travel. The effect of the program was evaluated 3 months after implementation. Patients and Methods Each study participant received a videotape that demonstrated 30 minutes of low-capacity aerobic exercise. Participants were advised to exercise by following the demonstration on the videotape. Encouragement was given over the telephone. Self-reports on practice were recorded in a log book that was also provided. The effect of the program was evaluated by comparing outcomes data before, and 3 months after, implementation of the program. Outcomes assessment included functional mobility (timed “Up & Go” test), muscle flexibility (“Sit & Reach” test), physical capacity (“Six-Minute Walk”), and quality of life [Kidney Disease Quality of Life Short Form (KDQOL-SF)]. Results The program began with 72 participants. Over time, 39 dropped out. The remaining 33 participants included 11 men and 22 women with a mean age of 52.8 ± 9.8 years. They exercised 3 – 7 times weekly. Significant improvements were observed in the timed “Up & Go” ( p = 0.003) and “Sit & Reach” ( p < 0.001) tests. Improvements in the “Six-Minute Walk” ( p = 0.130) and in KDQOL-SF scores for emotional well-being ( p = 0.456), pain ( p = 0.100), burden of kidney disease ( p = 0.061), and general health ( p = 0.085) were statistically insignificant. Conclusions Physically, patients with ESRD benefit from home-based low-capacity aerobic exercise. A home-based program provides an alternative to outdoor and group exercise. In view of a high drop-out rate, intensive promotion and encouragement should be considered to achieve a positive outcome.

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Randomized clinical trial on the effect of a supervised exercise program on quality of life, fatigue, and fitness following esophageal cancer treatment (PERFECT study).

Journal of Clinical Oncology ◽

10.1200/jco.2020.38.15_suppl.12055 ◽

2020 ◽

Vol 38 (15_suppl) ◽

pp. 12055-12055

Author(s):

Anne Maria May ◽

Jonna van Vulpen ◽

Anouk E Hiensch ◽

Jelle P. Ruurda ◽

Grard Nieuwenhuijzen ◽

...

Keyword(s):

Quality Of Life ◽

Clinical Trial ◽

Esophageal Cancer ◽

Cardiorespiratory Fitness ◽

Exercise Intervention ◽

Exercise Program ◽

Post Intervention ◽

Supervised Exercise ◽

Supervised Exercise Program

12055 Background: Patients with potentially curable esophageal cancer are often treated with chemoradiotherapy followed by surgery. This treatment might have a negative impact on physical fitness, fatigue and quality of life (QoL). In patients with other types of cancer, evidence suggests that physical exercise reduces treatment related side effects. We investigated whether a supervised exercise program also beneficially affects QoL, fatigue and cardiorespiratory fitness (CRF) in patients after treatment for esophageal cancer. Methods: The multicenter PERFECT study randomly assigned patients in the first year after esophagectomy to an exercise intervention (EX) or usual care (UC) group. EX patients participated in a 12-week moderate to high intensity aerobic and resistance exercise program supervised by a physiotherapist. UC patients were advised to maintain their physical activity levels. Attendance and compliance with the exercise intervention protocol were retrieved from exercise logs. QoL (primary outcome, EORTC-QLQ-30, range 0-100), fatigue (MFI-20, range 4-20) and CRF (cardiopulmonary exercise testing) were assessed at baseline and after 12 weeks (post-intervention). The outcomes were analyzed as between-group differences using either linear mixed effects models or ANCOVA adjusted for baseline and stratification factors (i.e. sex, time since surgery, center), according to the intention-to-treat principle. Results: A total of 120 patients (age 64±8) were included and randomized to EX (n = 61) or UC (n = 59). Patients in the EX group participated in 96% (IQR:92-100%) of the supervised exercise sessions and compliance with all parts of the exercise program was high ( > 90%). Post-intervention, global QoL was not statistically different between groups, but significant (p < 0.05) beneficial EX effects were found for QoL-Summary scores (between-group difference 3.5, 95% CI 0.2;6.8) and QoL-role functioning (9.4, 1.3;17.5). Physical fatigue wat non-significantly lower in the EX group (-1.2; -2.6;0.1, p = 0.08). CRF was significantly higher (VO2peak (1.8 mL/min/kg, 0.6;3.0) following the EX intervention. Conclusions: Patients were well capable to complete an intensive supervised exercise program after esophageal cancer treatment, which led to small but significant improvements in several aspects of QoL and cardiorespiratory fitness. Our results suggest that supervised exercise is a beneficial addition to routine care of patients with esophageal cancer. Clinical trial information: NTR5045 .

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MO841EFFICACY OF PHYSICAL EXERCISE IN PERITONEAL DIALYSIS PATIENTS: A SECONDARY ANALYSIS OF THE EXCITE TRIAL

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfab098.0033 ◽

2021 ◽

Vol 36 (Supplement_1) ◽

Author(s):

Francesca Mallamaci ◽

Vincenzo Antonio Panuccio ◽

Maria Carmela Versace ◽

Giovanni Luigi Tripepi ◽

Graziella D'Arrigo ◽

...

Keyword(s):

Quality Of Life ◽

Peritoneal Dialysis ◽

Secondary Analysis ◽

Exercise Program ◽

Active Group ◽

Control Group ◽

Dialysis Patients ◽

Home Based ◽

Low Intensity Exercise

Abstract Background and Aims Although physical activity has been documented to be effective in many categories of high-risk patients and more recently also in dialysis patients, there are no studies specifically focused on Peritoneal Dialysis (PD) patients. The peculiarity of this treatment modality for uremia is that it is carried out at the patient's home while the vast majority of physical exercise in dialysis patients is carried out during the hemodialysis (HD) session, then they are not applicable for PD patients. The Excite trial (JASN 2017; 28:1259-1268) is a home-based, individualized, low-intensity exercise program. In this multicenter, randomized clinical trial, the EXerCise Introduction To Enhance performance in dialysis patients trial (EXCITE), we aimed to investigate whether this home exercise program improves the degree of fitness and quality of life in patients with CKD-5D (Hemodialysis and Peritoneal Dialysis patients). The EXCITE home based clinical trial, is the first and may be the only one, involving peritoneal dialysis patients and this is of unique importance for the scientific community. Method We performed a secondary analysis of 35 peritoneal dialysis (PD) patients (age: 64±11 years; 74% males; 17% diabetics) who participated to the Exercise Introduction to Enhance Performance in Dialysis (EXCITE) trial, a 6-month randomized, multicenter trial testing whether a simple, personalized walking exercise program at home, managed by dialysis staff, improves functional status in adult patients on dialysis. The main study outcomes included change in physical performance at 6 months, assessed by the 6-minute walking test (6MWD) and the five times sit-to-stand test (STS), and in quality of life, assessed by the Kidney Disease Quality of Life Short Form (KDQOL-SF) questionnaire. Data are summarised as median and interquartile range (IQR). Results Out of 35 PD patients, 14 resulted to be allocated to the active arm and the remaining 21 to the control arm of the trial, and all completed the 6-month active phase of the trial. At baseline, the two groups did not differ as for age, gender, smoking, diabetes, and NYHA class (p ranging from 0.41 to 1.00) as well as for baseline values of 6MWD (active group, median 344 m, IQR: 307-440 m versus control group, median 302 m, IQR: 263-425m, P=0.12) and STS test (active group, median 18.2, IQR: 17.1-18.8 sec versus control group, median 20.2, IQR 16.2-27.1, P=0.25). During the 6 month period, there was a 34.0 m median increase of 6MWD (IQR: from 16.3 to 61.3 m) in the active group and only a modest increase of the same test in the control group (median: 14.0 m; IQR: from -39.5 to 38.5 m) and the between arms difference was statistically significant (P=0.034). No between arms difference was found in the STS test change (P=0.70). At 6 months, the quality of social interaction in the kidney disease component of the KDQOL-SF remained stable in patients of the active arm (median change from baseline: 0.0, IQR: from -5.0 to 17.5) whereas it decreased in patients in the control arm (median change from baseline: -5.8, IQR: from – 20.0 to -1.3) (between-arms difference, P=0.032). Conclusion The results of this multicentre trial involving PD patients show that a simple, personalized, home-based, low-intensity exercise program is feasible in PD patients and it may improve physical performance and quality of life in this high risk category of patients.

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