scholarly journals Treatment of Subclinical Hypothyroidism can Improve Weight Gain in Children with Failure to Thrive: A Case Series

2016 ◽  
Author(s):  
Jordan E Pinsker
Keyword(s):  
Weight Gain ◽  
Subclinical Hypothyroidism ◽  
Case Series ◽  
Failure To Thrive

scholarly journals AN AYURVEDIC MANAGEMENT OF SUBCLINICAL HYPOTHYROIDISM - A CASE REPORT

2018 ◽  
Vol 6 (5) ◽  
pp. 481-486
Author(s):  
Dnyaneshwar Kantaram Jadhav
Keyword(s):  
Internal Medicine ◽  
Case Report ◽  
Weight Gain ◽  
Subclinical Hypothyroidism ◽  
Single Case ◽  
Excellent Result ◽  
Modern Medicine ◽  
Single Case Study ◽  
Ayurvedic Treatment

Ayurved is science of life. Its guide human being for living on preventive & curative both aspect. Its ancient knowledge which is still stand truth to time. There are many diseases which is not mentioned directly in Ayurveda texts is called as Anukta vikar. Subclinical hypothyroidism is one of such disease. Such disease specifically mentioned but its line of treatment described very well. The present case is 28 year old male patient was suffering from Bhaar vrudhi (weight gain) from last 2.5 years while symptoms like Drubalya (fatigue), Sheet prachiti (feeling excessive cold), Bhrama (vertigo),  Shwasakashtata (dyspnoea after walking), Katishool (backache) since last 2 years. Patient on modern medicine still he doesn’t get any satisfy relief, at the end patient decide to take Ayurvedic treatment only. For treatment patient was came to Nakshatra Ayurved Panchkarma clinic & Research center, Mumbai. Ayurvedic management include internal medicine, Rukshaya bashpa peti sweda. After 1.5 month patient got Excellent Result. All symptoms disappear, weight reduces up-to 4 kg, TSH level comes from 7.71 to 3.23. This is single case study, will Collect data of more cases for further Research.

BIRDS OF THE SAME FEATHER DO NOT ALWAYS FLOCK TOGETHER: AN ADRENAL CASE SERIES

2021 ◽  
pp. 81-82
Author(s):  
Ansari SS ◽  
Nayak PN ◽  
Sudhir S ◽  
Shirodkar D
Keyword(s):  
Case Series ◽  
Failure To Thrive ◽  
Optimal Dose ◽  
Bone Age ◽  
Rete Testis ◽  
Laboratory Evaluation ◽  
Adrenal Crisis ◽  
Salt Wasting ◽  
Adrenal Rest Tumor ◽  
Adrenal Rest

Introduction: Most common adrenocortical biosynthetic defect is 21-hydroxylase deciency usually presenting as atypical genitalia at birth in girls and adrenal crisis in males at 2-3 weeks of age. We present to you a case series of congenital adrenal hyperplasia(CAH) with heterogeneous presentation at varied ages.Case 1:Thirty-six-day old baby presented with atypical genitalia, failure to thrive and shock. Laboratory evaluation revealed:hyperkalemia, hyponatremia, markedly elevated 17OH-progesterone(24200ng/dl)and karyotype 46XX.Case 2: One-year-4-month old boy known case of salt-wasting CAH who was on regular oral hydrocortisone and udrocortisone brought with the acute gastroenteritis. Investigations revealed elevated markers for sepsis, hypocortisolemia(1.37 mcg/dl) and high 17-OH-progesterone(588 ng/dl). Case 3: Five-year10-month old boy, known case of salt-wasting CAH on irregular medication and poor compliance presented with enlarged penile length. On evaluation his SMR staging=A1P3TV4/4ml, Height age:7.6 year and bone-age was 11.6 years. Endocrine evaluation demonstrated gonadotropinindependent precocity(Testosterone=109ng/dl, FSH=0.31 IU/ml, LH<0.10 IU/ml, 17-OH-Progesterone:25400ng/dl).Scrotal ultrasound showed hypoechoic areas in rete-testis suggestive of probable tesicular-adrenal-rest-tumor(TART).All patients were treated with hydrocortisone, udrocortisone and uid resuscitation.Conclusion:Diagnosis of CAH doesn't always depend on atypical genitalia. Continued adherence to the optimal dose of steroids, regular monitoring and strict advice during illness is as important as appropriate and timely management of the adrenal crisis.

Benefits of Breast Milk

PEDIATRICS ◽  
1980 ◽  
Vol 65 (1) ◽  
pp. 192-193
Author(s):  
Peter D. Magnus
Keyword(s):  
Weight Gain ◽  
Breast Milk ◽  
Breast Feeding ◽  
English Literature ◽  
Failure To Thrive ◽  
Infant Weight Gain

I was delighted to read of Dr Weichert's results in her article "Lactational reflex recovery in breast-feeding failure."1 All four infants would have been labeled "failure to thrive" in most pediatric centers with possible interruption of the precious lactation bond by formula supplements,2 as recent articles in the English literature have suggested.3,4 The Lact-Aid supplementer, utilized with all four mother-infant dyads, helped correct the problems of breast milk insufficiency and poor infant weight gain. The Lact-Aid is used not only to correct insufficiency and restore confidence, but also to alter sucking defects in babies who have not been acclimated to a constant pattern of good sucking.

Six Patients with MethylmalonicAcidemia and Their Outcome: A Literature Review and Case Series

2020 ◽  
Author(s):  
Naser Ali Mirhosseini ◽  
Sana Taghiyar ◽  
Mahdieh Saatchi
Keyword(s):  
Metabolic Acidosis ◽  
Quantitative Analysis ◽  
Progressive Failure ◽  
Clinical Manifestations ◽  
Case Series ◽  
Failure To Thrive ◽  
Feeding Problems ◽  
Urinary Organic Acid ◽  
Severe Metabolic Acidosis ◽  
Recurrent Vomiting

Background: Methylmalonic acidemia (MMA) is a congenital disorder due to the defects in the propionate pathway. It results from a deficiency in methylmalonyl coenzyme A mutase or one of the steps of the synthesis of the cobalamin (B12) cofactors for the enzyme. There is deficiency of methylmalonylcoAmutase (MCM) in the classic MMA. It presents with severe metabolic acidosis in the first month of life, progressive failure to thrive, feeding problems, recurrent vomiting, dehydration, hepatomegaly, lethargy, seizures, and developmental delay. Quantitative analysis of urinary organic acid patterns by GC-MS is used in MMA diagnosis. Treatment with large doses of hydroxocobalamin is helpful in some cases of MMA.                                                                                        Case presentation:We Reported 6 patients with MMA with a variety of clinical manifestations and outcomes. Conclusion: The overall prognosis of classic MMA remains doubtful, whereas vitamin B12 responsive MMA has a reasonable outcome.

scholarly journals When does slow weight gain become 'failure to thrive'?

1991 ◽  
Vol 66 (7) ◽  
pp. 905-906 ◽  
Author(s):  
B Porter ◽  
D Skuse
Keyword(s):  
Weight Gain ◽  
Failure To Thrive

Early Initiation of Enteral Nutrition Results in Catch-Up Weight Gain in Children Diagnosed with Failure to Thrive

2008 ◽  
Vol 108 (9) ◽  
pp. A30
Author(s):  
C. DeTallo ◽  
M. Miller ◽  
L. Jeffers ◽  
S. Shainker ◽  
A. Adler ◽  
...  
Keyword(s):  
Weight Gain ◽  
Enteral Nutrition ◽  
Failure To Thrive ◽  
Early Initiation ◽  
Catch Up

Prospective Evaluation of Weight Gain in Both Nonorganic and Organic Failure-to-Thrive Children

1989 ◽  
Vol 10 (1) ◽  
pp. 27???31 ◽  
Author(s):  
WILLIAM G. BITHONEY ◽  
JAMES McJUNKIN ◽  
JOANNE MICHALEK ◽  
HARWOOD EGAN ◽  
JOHN SNYDER ◽  
...  
Keyword(s):  
Weight Gain ◽  
Failure To Thrive ◽  
Prospective Evaluation ◽  
Organic Failure

scholarly journals Efficacy of Ayurveda Interventions Specifically on Weight Gain in the Management of Protein Energy Malnutrition in Children: A Systematic Review Protocol

2021 ◽  
pp. 252-258
Author(s):  
Sumod Khedekar ◽  
Renu Rathi ◽  
Bharat Rathi ◽  
Heramb Hattikar ◽  
Suraj Patlekar ◽  
...  
Keyword(s):  
Systematic Review ◽  
Weight Gain ◽  
Case Reports ◽  
Protein Energy Malnutrition ◽  
Case Series ◽  
Clinical Work ◽  
Treatment Modalities ◽  
Public Health Issue ◽  
Future Research ◽  
Protein Energy

Background: In India, Protein Energy Malnutrition (PEM)remains a significant and challenging public health issue despite implementing different nutritional policies over the period. It is also accompanying with aggravated risk of all-cause morbidity, as well as fatality Ayurveda mentions about various nutritional disorders such as karshya, balashosha, phakka, yakshma which are having similar symptomatology and treatment approach as that of the PEM. Several clinical studies have been conducted and some are under trial but systematic review is still pending to explore an effective treatment modality to combat PEM in Children. Aim: A systematic review to evaluate the efficacy of Ayurveda Interventions specifically on weight gain in the Management of Protein Energy Malnutrition in Children. Materials and Methods: A systematic review which will evaluate published clinical work of Ayurveda treatment modalities specifically for weight gain in the management of PEM in children that will involve “The randomized controlled trials (RCTs), multiple-arms clinical trials, quasi-experimental trials, observational studies (case series and case reports) through databases like PubMed, COCHRANE, AYUSH Research Portal, DHARA; Google Scholar; etc. and Ayurveda compendia to fetch complete available literature.” Observations and Discussion: The work of selection of the studies, data extraction, and synthesis will be taken up. Established guidelines for study selection, quality assessment, and narrative synthesis will be followed. Risk of bias assessment will be performed. A protocol will be designed that will ensure transparency for the completed review. Results of the study will be elaborately synthesized. The data will be presented in percentage, count and frequency; and if we find the data to be sufficiently homogeneous then meta-analysis will be carried out. Conclusion: The results obtained from this systematic review will be useful in identifying the evidence-based efficacy of Ayurveda interventions on weight gain in the Management of PEM. It will also provide substratum for future research studies for generating good-quality evidence that can be helpful to design new health policy to combat PEM effectively.

scholarly journals Weight gain in patients with severe atopic dermatitis treated with dupilumab: a case series

2020 ◽  
Author(s):  
Emma Kristin Johansson ◽  
Lina Ulrika Ivert ◽  
Baltzar Bradley ◽  
Maria Lundqvist ◽  
Maria Bradley
Keyword(s):  
Atopic Dermatitis ◽  
Weight Gain ◽  
Weight Change ◽  
Rating Scale ◽  
Case Series ◽  
Interleukin 4 ◽  
Rank Test ◽  
Severe Atopic Dermatitis ◽  
Night Sleep

Abstract Background Dupilumab, targeting the interleukin-4α receptor and inhibiting the action of interleukin-4 and interleukin-13, was recently approved for treatment of moderate to severe atopic dermatitis. There is limited data on long-term effects and safety among patients with severe atopic dermatitis treated with dupilumab. Weight gain was observed among patients treated with dupilumab in our clinic. The aim was to describe weight change in a case series of patients with severe atopic dermatitis treated with dupilumab from baseline to follow-up after 12 months, and to analyze if weight change was associated with effect of treatment, reported appetite, and/or disturbed night sleep due to itching. Methods All patients with atopic dermatitis receiving systemic treatment at the Unit of Dermatology, Karolinska University Hospital, have been registered and monitored consecutively since January 2017. This case series constituted all patients who started treatment on dupilumab or methotrexate between 10 January 2017 and 30 June 2019 with at least 6 months of follow-up within the study period. The following variables were monitored at start of and during treatment: Eczema Severity Score Index, Patient-Oriented Eczema Measure, visual analogue scale for pruritus 10cm, Montgomery-Åsberg Depression Rating Scale, Dermatology Life Quality Index, and weight. Data analyses were performed using two-sample Wilcoxon-Mann-Whitney rank-sum test, or the Wilcoxon matched-pairs sign-rank test with a p-value <0.05 considered as statistically significant. Results Patients treated with dupilumab (n=12) gained weight (mean 6.1 kg, range [0.1–18.0], p=0.002) after one year on treatment. The majority of patients showed a good response to treatment with dupilumab (n=11); at follow-up at 6, 9, or 12 months, they reached EASI-90 (n=6), EASI-75 (n=4), or EASI-50 (n=1). There was no significant association between weight gain and treatment response, reported appetite, or disturbed night-sleep due to itch. Patients treated with methotrexate showed no significant weight change (n=8). Conclusions To our knowledge, this is the first report on a possible association between weight gain and dupilumab treatment; the extent of the association is yet to be seen, as is the mechanism behind this finding.

scholarly journals A Holistic Supplementation Regimen for Tongue-Tied Babies With Slow Weight Gain and Failure to Thrive

2018 ◽  
Vol 9 (2) ◽  
pp. 78-87
Author(s):  
Asti Praborini ◽  
Anjar Setiani ◽  
Agusnawati Munandar ◽  
Ratih Ayu Wulandari
Keyword(s):  
Weight Gain ◽  
Nutritional Status ◽  
Complementary Feeding ◽  
Failure To Thrive ◽  
Cross Sectional Study ◽  
Milk Supply ◽  
Upper Lip ◽  
Cross Sectional ◽  
Holistic Management ◽  
Type 3

Breastfeeding is the best way to feed infants, but optimal milk transfer and weight gain depend on good latching. Tongue- and lip-tie can prevent successful latching and prevent adequate nutrition. Tongue- and lip-tied babies can either have slow weight gain (SWG) or failure to thrive (FTT). We examine the effect of a holistic supplementation regimen on tongue-tied babies with SWG and FTT. This was a descriptive, cross-sectional study of 55 tongue- and lip-tied babies with SWG and FTT at KMC Hospital, Jakarta, Indonesia. All babies underwent frenotomy and received supplementation with formula (64%) or pasteurized donor breast milk, using either a modified lactation aid (78%) or the Medela Supplemental Nursing System (22%). All mothers received domperidone and acupuncture to improve milk supply. A majority of babies had type 3 tongue-tie (46%) and class 3 upper lip-tie. Twenty-five subjects (45%) had SWG, and 30 subjects (55%) had FTT. All mothers had low milk supply. At-the-breast supplementation improved the nutritional status of 44/55 subjects (80%,p< .001), whereas 11 subjects received early complementary feeding at 4 months of age. By the end of the study, all subjects were solely breastfed without at-the-breast supplementation. The holistic management of tongue- and lip-tied babies with SWG or FTT consisting of frenotomy, at-the-breast supplementation, domperidone, and acupuncture improved infant nutritional status and the mother’s milk supply. Babies could breastfeed without supplementation after treatment and gained weight.

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