Quality of life of patients with chronic cerebral ischemia

2017 ◽  
Vol 117 (4) ◽  
pp. 56
Author(s):  
M. V. Avrov
Keyword(s):  
Quality Of Life ◽  
Cerebral Ischemia ◽  
Chronic Cerebral Ischemia

scholarly journals Cognitive functions, quality of life in patients with dyscirculatory (vascular) encephalopathy II stage in northerners from the position of ICF

2021 ◽  
Vol 27 (3) ◽  
pp. 351-364
Author(s):  
E. D. Yakovchuk ◽  
G. O. Penina
Keyword(s):  
Quality Of Life ◽  
Cerebral Ischemia ◽  
Emotional Disorders ◽  
Cognitive Functions ◽  
Komi Republic ◽  
International Classification Of Functioning ◽  
Chronic Cerebral Ischemia ◽  
Sf 36

Objective. The aim of the study was to analyze cognitive functions, emotional disorders, the quality of life with the application of the International Classification of Functioning (ICF) in patients with chronic cerebrovascular diseases, dyscirculatory (vascular) encephalopathy II stage in the Komi Republic. Design and methods. In the clinics of the Komi Republic, we examined 126 people (mean age — 65,8 ± 10,1 years; women comprised 76 participants, 60,3 %, p ≤ 0,05) with dyscirculatory (vascular) encephalopathy. Complaints and anamnesis were analyzed, somatic and neurological status, cognitive functions, emotional status, and sleep were assessed. Results. Out of 126 patients, 44,5 % patients are employed (56 people). Among non-working patients with an established group of disability, 35,7 % (in 14,3 % disability 2nd degree (10 people), in 21,4 % — disability 3rd degree (15 people), p ≤ 0,05). Among the workers, 3 people (5,3%) had disability 3rd degree. Hypertension (HTN) I stage was detected in 10,6 %, HTN II stage — in 44,4 %, HTN III stage — in 45 % (p ≤ 0,05); 27,8 % had history of ischemic heart disease, 7,2 % — myocardial infarction, 19,1% — cerebrovascular accident, 8,6% — heart rhythm disturbances, 15,8 % — significant stenosis of the brachiocephalic arteries. Based on memory function assessment by ICF, none demonstrated normal results. Mild cognitive impairment was usually found, and there was no case of dementia. Dysfunction in the domain of blood pressure function was found in all patients. The dysfunction of blood vessels was found in all patients with chronic cerebral ischemia II stage. Daily activities were reduced due to the physical dysfunction. According to the total assessment of health status by the SF-36 scale, the physical and mental components of health were similarly decreased. Conclusions. The SF-36 (questionnaire for assessing the quality of life) and ICF (International Classification of Functioning, Disabilities and Health) complement each other. Cognitive scales are the basic tools for examination of patients with chronic cerebral ischemia, making diagnosis according to ICF, and treating cognitive, physical and emotional disorders in dyscirculatory (vascular) encephalopathy.

scholarly journals Balneotherapy and physiotherapy in treatment of cognitive and psychoemotional disorders in patients with chronic cerebral ischemia

2020 ◽  
Vol 17 (4) ◽  
pp. 178-184
Author(s):  
Lyubov A. Cherevaschenko ◽  
Artem A. Serebryakov ◽  
Nikolay N. Kulikov ◽  
Anatolii T. Tereshin ◽  
Igor A. Cherevashchenko
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Cerebral Ischemia ◽  
Electrostatic Field ◽  
Low Frequency ◽  
Chronic Cerebral Ischemia ◽  
Health Resort ◽  
Treatment Methods ◽  
Treatment Stage

Background. Chronic cerebral ischemia, or discirculatory encephalopathy, is one of the most common neurological diagnosis in Russia. This condition is defined as a chronic, progressive, non-stroke-related vascular lesion of the brain, which is manifested predominantly by cognitive impairment. Therapeutic measures for cognitive impairment include, first of all, the prevention of acute cerebrovascular accidents and chronic vascular cerebral insufficiency. The development and implementation of highly effective non-drug treatment methods, having few side effects, is an urgent problem in contemporary medicine. Such treatment methods can include balneotherapy and physiotherapy. Aim: to justify the possibility and expediency of applying at the health resort treatment stage the combined use of iodine-bromine baths and a pulsed low-frequency electrostatic field in patients with chronic cerebral ischemia in order to correct cognitive and psychoemotional disorders and improve the quality of life. Methods. The study included 90 patients with chronic cerebral ischemia, who were randomly divided into 3 treatment groups. The control group patients received iodine-bromine baths, the comparison group patients received exposure to an alternating pulsed low-frequency electrostatic field using the HIVAMAT-200 apparatus, and the main group patients received iodine-bromine baths and exposure to a pulsed low-frequency electrostatic field. The cognitive and emotional-volitional sphere was studied using standard neuropsychological techniques, namely the minimum cognitive deficit scale Mini Mental State Examination (MMSE); Lurias test, the Clock Drawing test, Schulte tables, and Yu.L. Hanins anxiety scales. The study of quality of life was performed using the Russian version of the general questionnaire MOS SF 36 Iterm Short-Form Health Survey. Results. It has been proved that as a result of treatment, disorders of memory and attention are reduced, the general cognitive status of patients is improved, which slows down the disease progression, reduces the risk of vascular catastrophes and dementia. Conclusion. New medical technologies developed for the treatment of patients with chronic cerebral ischemia at the health resort treatment stage are highly effective, pathogenetically substantiated, and can be recommended for widespread use in a network of health resort institutions and rehabilitation and preventive institutions of practical health care.

scholarly journals Meta-analytical evaluation of the clinical efficacy of a complex metabolic neuroprotector in patients with chronic cerebral ischemia

2022 ◽  
Vol 66 (9-10) ◽  
pp. 39-53
Author(s):  
M. V. Zhuravleva ◽  
G. I. Gorodetskay ◽  
T. S. Reznikova ◽  
N. S. Vasyukova ◽  
V. V. Arkhipov ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Cerebral Ischemia ◽  
Clinical Efficacy ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Randomized Study ◽  
Significant Heterogeneity ◽  
Chronic Cerebral Ischemia

The aim of the study is to evaluate the clinical efficacy, safety, and impact of the complex metabolic neuroprotector on the patients’ quality of life (CMN) Cytoflavin in tablets, as well as in the course of stepwise pharmacotherapy of patients with chronic cerebral ischemia (CCI) of various etiologies, followed by meta-analysis, on the basis of a systematic review of published clinical studies.Material and methods. A selection of randomized controlled trials was carried out over the past 15 years, in which CMN Cytoflavin was used in the tablet dosage form or in a stepwise course of therapy in at least 25 patients diagnosed with chronic cerebral ischemia with a total course of therapy of at least 25 days. The assessment of CMP clinical efficacy and the analysis of formalized indicators of clinical efficacy (relative risk, odds ratio, frequency of outcomes, values of absolute and relative benefits, etc.) was carried out.Results and conclusion. 403 publications for 2000–2017 describing the use of CMN Cytoflavin were analyzed. 16 studies were selected for the systematic review, the meta-analysis included 6 randomized clinical trials and one non-randomized study of the use of CMN in patients with CCI. The data of the systematic review and meta-analysis showed a sufficient efficacy of complex metabolic neuroprotector use in patients with chronic cerebral ischemia. However, the meta-analysis revealed significant heterogeneity between the studies. The drug has a beneficial effect on the quality of life of patients, increases the likelihood of a positive outcome in relation to the relief of asthenic and vestibular-atactic syndromes, in relation to complaints of increased fatigue, headache, dizziness, noise in the head, impaired coordination. It improves cognitive functions, exhibits sufficiently high tolerance and safety.

Clinical and neuroimaging features of chronic cerebral ischemia in polycythemia vera

2021 ◽  
pp. 58-62
Author(s):  
G. V. Zyrina ◽  
T. A. Slyusa
Keyword(s):  
Cerebral Ischemia ◽  
Polycythemia Vera ◽  
Mini Mental State Examination ◽  
Comparison Group ◽  
Cognitive Disorders ◽  
Chronic Cerebral Ischemia ◽  
State Examination ◽  
The Brain

The purpose of the study. To study clinical and neuroimaging features of chronic cerebral ischemia (CCI) in polycythemia vera (PV).Materials and methods. 66 patients with PV were examined – the main group (43 men, 23 women; mean age 62.0 ± 3.4 years), of which 64 (97.0%) patients were diagnosed with CCI. The comparison group consisted of 85 patients with CCI (34 men, 51 women; mean age 67.7 ± 4.6 years), who developed against the background of cerebral vascular atherosclerosis and arterial hypertension. To identify cognitive disorders, we used Mini Mental State Examination (MMSE). Insomnia was studied in accordance with the criteria of the International Classification of Sleep ICDS‑22005. The quality of sleep was determined using a questionnaire from the Federal Somnological Center. Neuroimaging (MRI of the brain) was performed on Siemens Symphony 1.5 T and GE Signa 1.5 T tomographs.Results. Subjective symptoms CCI are characterized by a greater representation of asthenic and insomniac disorders. Transient ischemic attacks in patients with PV are significantly more common than in the comparison group, their frequency depends on the duration of PV. The revealed changes in MRI of the brain in the majority of PV patients with CCI are characteristic of multiinfarction vascular encephalopathy; in the comparison group, changes that characteristic for subcortical arteriosclerotic encephalopathy were more often recorded.

scholarly journals Comparative analysis of clinical and neurological manifestations in patients with chronic cerebral ischemia and chronic heart failure with stored and reduced release fraction

2017 ◽  
pp. 42-48
Author(s):  
N. Zhhilova
Keyword(s):  
Heart Failure ◽  
Comparative Analysis ◽  
Cerebral Ischemia ◽  
Chronic Heart Failure ◽  
The State ◽  
Chronic Cerebral Ischemia ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

Chronic heart failure relates to the priorities of national health systems in most countries due to the high prevalence, steady increase in the number of new cases in all countries, frequent repeated hospitalizations, poor quality of treatment, high levels of disability and mortality, and increased treatment costs. An important multidisciplinary task is to study the state of the brain in the background of chronic cardiac pathology, which is associated with a violation of the pumping function of the heart and central hemodynamics. The purpose of the study was to investigate the state of the cognitive and psychoemotional sphere in patients with chronic cerebral ischemia and chronic heart failure with a preserved and reduced release fraction. In a comparative analysis in patients with chronic cerebral ischemia and chronic heart failure with a preserved and reduced emission fraction, a statistically significant difference was not found. Direct correlation dependence with complaints of memory impairment (r = 0.34), anxiety manifestations (r = 0.44), depression (r = 0.42). According to the study, cognitive impairment was observed in 95.3% of patients in group 1 and in 71.1% of patients in group 2. Dementia of light severity was found in patients with 1 group in 18.6% and in patients with 2 groups in 11.1%. Data from a neuropsychological study showed cognitive safety in 4.6% of patients in group I and 28.8% in group 2, which were characterized by mild modal-nonspecific mantle disorders. Premedicinal cognitive disorders were observed in group 1 in 33 (76.7%) patients and in 27 (60%) patients in group 2 (Table 1). There was a statistically significant difference between the groups p = 0.009 (p <0.05) and the direct correlation between MMSE and age (r = 0.63), quality of life (r = 0.31), complaints when considering deterioration of memory (r = 0.39).

scholarly journals Contributing factors to quality of life after vertebral artery dissection: a prospective comparative study

BMC Neurology ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Rainer J. Strege ◽  
Reinhard Kiefer ◽  
Manfred Herrmann
Keyword(s):  
Quality Of Life ◽  
Cerebral Ischemia ◽  
Functional Outcome ◽  
Posttraumatic Stress ◽  
Posttraumatic Stress Symptoms ◽  
Artery Dissection ◽  
Stress Symptoms ◽  
Good Functional Outcome

Abstract Background Vertebral artery dissection (VAD) may cause cerebral ischemia and impair quality of life (QOL) despite of good functional outcome. The aim of this study was the multimodal analysis of patient characteristics after VAD to identify contributing factors. Methods In an exploratory study, 34 consecutive patients with first-ever spontaneous VAD were prospectively examined in comparison to 38 patients with cerebral ischemia without dissection and 25 stroke mimics as control groups. Multimodal assessment was performed for clinical, neurological, cognitive, psychological and radiological data at baseline and for QOL, functional outcome, and stress symptoms by questionnaire at six months follow-up. Subgroup analysis stratified for QOL by Stroke Specific Quality of Life Scale (SS-QOL) were done for patients with good functional outcome (modified Ranking Scale (mRS) scoring 0–2). Predictors for QOL at follow-up were analyzed by regression model. Results 88.2% of patients with VAD suffered from acute cerebral ischemia. Thirteen of 32 VAD patients (40.6%) rated QOL at follow-up as bad (SS-QOL score ≤ 3.9) despite of good functional outcome (mRS score 0–2). Subgroup analysis yielded significantly higher scores for posttraumatic stress symptoms (p = 0.002) in this subgroup. Posttraumatic stress symptoms, severity of neurological disorders, and impaired neuropsychological baseline performance proved to be independent predictors for reduced QOL at follow-up according to regression analysis. Conclusion VAD leads to impaired QOL at 6 months follow-up due to multiple factors. The data suggest that posttraumatic stress symptoms are of significant importance for the QOL after VAD. Clinical monitoring should address this topic to make timely treatment possible.

scholarly journals Pathophysiologic aspects of the development of cognitive disorders in chronic heart failure in elderly patients

2018 ◽  
Vol 99 (2) ◽  
pp. 260-264 ◽  
Author(s):  
M A Pokachalova ◽  
M V Silyutina
Keyword(s):  
Heart Failure ◽  
Cerebral Ischemia ◽  
Chronic Heart Failure ◽  
Elderly Patients ◽  
Cognitive Dysfunction ◽  
Age Groups ◽  
Cognitive Disorders ◽  
Chronic Cerebral Ischemia ◽  
Course Of Disease

The present literature review presents current views on pathophysiologic aspects of the formation and progression of cognitive disorders in chronic heart failure in elderly patients. Advanced age itself is an important predictor of the development of cardiovascular, neurodegenerative and other diseases. Involutive changes of cardiovascular system are known to potentiate the development of chronic heart failure. Heart failure in older people usually develops gradually. Formation of the cognitive deficit in heart disease is associated with chronic cerebral ischemia as well as a cascade of neurochemical processes occurring in the brain, eventually forming a vicious circle. Often the symptoms of cerebral ischemia due to reduced stroke volume occur much earlier than congestion signs in other organs and systems. Chronic cerebral ischemia that occurs due to violation of cerebral hemodynamics, is associated with both extracerebral and intracerebral causes, which in turn contributes to the development of chronic brain hypoxia and aggravation of cognitive dysfunction. Thus, the features of the development and course of disease in people of older age groups indicate that in geriatric practice existing diagnostic schemes are not always applicable. When observing patients of elderly and senile age with chronic heart failure, during the assessment of their condition and running diagnostic tests, special attention should be payed to the earliest detection of cognitive dysfunction signs in order to correct the patient's treatment and improve quality of life.

scholarly journals DYNAMICS QUALITY OF LIFE INDICATORS IN CHILDREN WITH VENTRICULAR DEFECT IN ТНЕ PROCESS OF SANATORIUM-RESORT TREATMENT

2020 ◽  
Vol 26 (3) ◽  
pp. 114-118
Author(s):  
N. N. Kaladze ◽  
О. N. Rybalko ◽  
А. Уи. Iushchenko
Keyword(s):  
Quality Of Life ◽  
Cerebral Ischemia ◽  
Reliable Method ◽  
Significant Contribution ◽  
Mental Development ◽  
Psychomotor Development ◽  
Body Formation ◽  
Quality Of Life Indicators ◽  
Functional Features

The psychomotor development of children is a complex parameter for their body formation and a diagnostically reliable method for assessing mental and somatic health. At present, the number of newborns is increasing, especially among premature children, who develop serious neurological problems that were initially determined by a delay in psychomotor development and were regarded as morphological and functional features of an immature child. In our country and abroad, there are various methods of eliminating the consequences of cerebral ischemia. In connection with this problem, we have treated patients with hydrotherapy and evaluated the results of the study on the Bayley scale for a comprehensive characteristic of motor and mental development. The obtained data also made a significant contribution to abilitation measures aimed at preventing cerebral ischemia consequences.

scholarly journals Peculiarities in the course of chronic cerebral ischaemia in senior age groups in the dynamics of medical rehabilitation under conditions of a specialized medical center

2009 ◽  
Vol 8 (3(2)) ◽  
pp. 30-35
Author(s):  
T. F. Popova ◽  
L. A. Klimova
Keyword(s):  
Quality Of Life ◽  
Cerebral Ischemia ◽  
Elderly Patients ◽  
Cerebral Ischaemia ◽  
Medical Center ◽  
Age Groups ◽  
Medical Rehabilitation ◽  
Cognitive Disturbances ◽  
In The Beginning

According to the data of the investigation it was established the connection between the intensity of neurological and cognitive disturbances, psychoemotional disturbances and changes of quality of life of the adult and elderly patients with chronicle cerebral ischemia. It was showed that using the rehabilitation therapy in the special referral medical center in the beginning stage of the disease bias for the better on quality of live of the patients.

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