scholarly journals Esophago-gastroduodenal ulceration complicated by duodenal perforation in a three year old Thoroughbred colt: a case report

2009 ◽  
Vol 54 (No. 8) ◽  
pp. 374-378 ◽  
Author(s):  
B. Bezdekova
Keyword(s):  
Duodenal Ulcer ◽  
Delayed Gastric Emptying ◽  
Endoscopic Examination ◽  
Gastric Ulceration ◽  
Exercise Intolerance ◽  
Duodenal Perforation ◽  
Endoscopic Appearance ◽  
Blood Examination ◽  
Septic Peritonitis ◽  
Gastroduodenal Ulceration

: A three year old Thoroughbred colt was admitted to our clinic because of chronic inapetence, weight loss and exercise intolerance. Clinical examination, blood examination and endoscopy were carried out. The endoscopic appearance of the distal esophagus was characterized by extensive and severe ulceration. Gastroscopy revealed severe diffuse ulceration of the entire nonglandular mucosa. A diagnosis of esophago-gastric ulceration and delayed gastric emptying was made. Shortly after endoscopic examination the colt developed acute severe colic with profuse diarrhea and was euthanized. Necropsy and histopathology were performed. The most notable abnormalities were severe and extensive esophageal, gastric and duodenal ulcerations. One duodenal ulcer was perforated and acute septic peritonitis developed. The diagnosis was thus confirmed and extended – esophago-gastroduodenal ulceration with complication of duodenal perforation.

LAPAROSCOPIC REPAIR OF PERFORATED DUODENAL ULCER PATCH VERSUS CONVENTIONAL SURGERY

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Dr. Anil Kumar Saxena ◽  
Dr. Devi Das Verma
Keyword(s):  
Duodenal Ulcer ◽  
Laparoscopic Repair ◽  
Open Repair ◽  
Wound Dehiscence ◽  
Duodenal Perforation ◽  
Perforated Duodenal Ulcer ◽  
Conventional Surgery ◽  
Duodenal Ulcers ◽  
Duration Of Operation ◽  
Repair Group

Introduction: For many surgeries for duodenal ulcer Laparoscopic repair has become gold standard for many elective procedures such as ant reflux procedures, laparoscopic cholecystectomy and in colorectal surgery. Although in the emergency setting such as in the management of perforated duodenal ulcer Laparoscopic repair has been slow and limited. Since 1990, for the treatment of perforated peptic ulcer Laparoscopic repair has been used which has been widely accepted as an effective method. Duodenal ulcer is defined as a peptic ulcer which develops in the first part of the small intestine called duodenum and usually present as a perforation of acute abdomen. In perforated duodenal symptoms as severe and sudden onset abdominal pain that is worse in right upper quadrant and epigastrium and usually followed by nausea and vomiting. In this situation there is rapid generalization of pain and in examination shows peritonitis with lack of bowel sounds. Aim: The main objective of this study is to evaluate outcome of laparoscopic surgery in comparison with conventional surgery. Material and methods: All the patients with clinically diagnosed with perforated duodenal ulcers presenting within 24 hours of symptoms and undergoing surgery were included during the study period. Total 50 patients were included with age group 15-65 years. All the patients with perforated duodenal ulcers were included which go through either conventional open or laparoscopic without omental patch repair. Result: Total 50 patients were included in these studies which were divided into two group with 25 patients in each group as laparoscopic duodenal perforation repair group and conventional open repair group. Mean duration of operation (in minutes) was 105.4±10.4 in laparoscopic duodenal perforation repair group whereas mean duration of operation (in minutes) was 67.3±8.6 in conventional open repair group. Mean duration of number of doses of analgesics required in laparoscopic group and conventional open group as 9.5±1.7 and 17.2± 3.1 respectively. Out of 25 patients in each group of laparoscopic duodenal perforation repair group and the conventional open repair group the outcome were noted with their post operative complication as shown in table no 5 below.   In Post-operative complications 21(84%) patients in laparoscopic duodenal perforation repair group and 14(56%) patients in conventional open repair group had no complications. 4 (16%) patients in the laparoscopic duodenal perforation repair group and 2(8%) patients in conventional open repair group showed Post-operative complications as chest infection. In the conventional open repair group  patients present with wound dehiscence and wound infection and Wound dehiscence and chest infection were 4(16%) and 5(20%) respectively whereas nil in Laparoscopic duodenal perforation repair group. Conclusion: Duodenal ulcer perforation is a life-threatening emergency which required urgent management for the patients. Due to the advance in duodenal ulcer perforation closure by laparoscopy it becomes popular and favorite choice. With certain criteria, laparoscopic closure of perforated duodenal ulcer is safe and effective though it was associated with longer operating time and had no impact on the outcome. Hence laparoscopic closure was better in comparison to open repair for the earlier returns to normal daily activities. Keywords:  Duodenal ulcer, Laparoscopic repair, Post-operative analgesia, conventional surgery

Study of factors affecting mortality and morbidity in patients presenting with peritonitis due to duodenal ulcer perforation

2021 ◽  
Vol 19 (2) ◽  
pp. 35-39
Author(s):  
Pradeep Chandra Sharma ◽  
Keyword(s):  
Duodenal Ulcer ◽  
Previous History ◽  
Common Factors ◽  
Duodenal Perforation ◽  
High Morbidity ◽  
Delayed Presentation ◽  
Mortality And Morbidity ◽  
Factors Affecting ◽  
Ulcer Perforation ◽  
Duodenal Ulcer Perforation

Background: Peptic ulcer disease in the general population had lifetime prevalence of 5-10% with incidence of 0.1–0.3% per year. Despite the tremendous improvement in preventive therapies, the rate of complication of this disease is still high and is burdened by high morbidity and mortality. In present study, we aimed to study factors affecting mortality and morbidity in patients presenting with peritonitis due to duodenal ulcer perforation at our tertiary hospital. Material and Methods: Present study was single-center, prospective, observational study conducted in patients admitted, diagnosed with duodenal ulcer perforation and surgically treated at our hospital. Results: In present study period total 56 patients were studied. All were male, most common age group was 51-60 years (37.5%) followed by 41-50 years (23.21%). Duration from onset of symptoms to admission was >24 hours (30.36%) in most of patients followed by 12-24 hours (28.57%). Most commons symptoms were pain in abdomen (100%), vomiting (100%). Anaemia (37.5%), LRTI and Pulmonary complications (19.64%), Diabetes mellitus (12.5%) and Hypertension (10.71%) were common comorbidities noted. Associated risk factors were previous history of PUD (41.07%), Alcohol use (64.29%), Cigarette smoking (51.79%) and Use of NSAIDs (12.5%). Presence of free gas under diaphragm was noted in 83.93% patients. Intraoperatively duodenal perforation diameter was 1–5 mm (60.71%) in most of patients followed by 6–10 mm (23.21%). Only 1 patient had duodenal perforation diameter was > 20mm. Common postoperative complications were wound infection (37.5%) and pulmonary infection (21.43%). In present study mortality within 1 month was noted in 13 patients (23.21%). Most common factors related to mortality were delayed presentation > 24 hours (61.54%), age > 60 years (46.15%), diabetes mellites (38.46%), Size of perforation > 1 cm (38.46%) and septicaemic shock (23.08%). Conclusion: Delayed presentation > 24 hours, age > 60 years size of perforation > 1 cm were common factors related to mortality in duodenal ulcer perforation patients.

Phenol poisoning in three dogs

2000 ◽  
Vol 36 (4) ◽  
pp. 317-321 ◽  
Author(s):  
TL Gieger ◽  
SS Correa ◽  
J Taboada ◽  
AM Grooters ◽  
AJ Johnson
Keyword(s):  
Oral Administration ◽  
Supportive Care ◽  
Coal Tar ◽  
Endoscopic Examination ◽  
Gastric Ulceration ◽  
The Internet ◽  
Muscle Enzymes ◽  
Hematological Abnormalities ◽  
Mucosal Necrosis

Three adult dogs were evaluated following oral administration of phenol by the owner. All three dogs experienced severe oral and gastric ulceration. Hematological abnormalities included neutropenia with the presence of toxic neutrophils, thrombocytopenia, and increased muscle enzymes. Endoscopic examination was performed, and biopsies yielded a diagnosis of gastric mucosal necrosis in two of the dogs. Following supportive care, the dogs recovered completely. Phenol is a caustic, highly poisonous derivative of coal tar. The dogs of this report were poisoned inadvertently by their owner who received misinformation concerning the use of this chemical via the Internet.

Spontaneous gastric rupture presenting as severe pneumoperitoneum in a cat with presumed idiopathic gastric ulceration

2020 ◽  
Vol 8 (1) ◽  
pp. e001049 ◽  
Author(s):  
Luis Mate de Haro ◽  
Beatriz Moreno-Aguado ◽  
Juan Martí ◽  
Darren Kelly
Keyword(s):  
Histological Analysis ◽  
Clinical Signs ◽  
Final Diagnosis ◽  
Acute Onset ◽  
Gastric Ulceration ◽  
Neoplastic Disease ◽  
Perforated Gastric Ulcer ◽  
Gastric Rupture ◽  
Septic Peritonitis ◽  
Diagnostic Investigations

An 11-year-old female British blue cat was referred for investigation of acute onset vomiting and marked abdominal enlargement. Diagnostic investigations confirmed a large volume of free gas within the abdomen and changes highly suspicious of an ulcerative gastric lesion. Exploratory surgery confirmed the presence of a perforated gastric ulcer and histological analysis showed only associated inflammatory change. The ulcerated lesions were resected, and the cat recovered rapidly with complete resolution of clinical signs. Spontaneous gastric rupture due complete perforation of an ulcer is rarely reported in cats. The vast majority of reported cases present with septic peritonitis, and the majority are subsequently diagnosed with neoplastic disease or a chronic inflammatory aetiology. The cat reported here had no evidence of septic peritonitis, and the authors feel a final diagnosis of idiopathic gastric ulceration is most likely.

Proximal Duodenal Perforation in Three Dogs Following Deracoxib Administration

2010 ◽  
Vol 46 (4) ◽  
pp. 255-258 ◽  
Author(s):  
J. Brad Case ◽  
Jennifer L. Fick ◽  
Matthew B. Rooney
Keyword(s):  
Gastrointestinal Disease ◽  
Case Series ◽  
Exploratory Laparotomy ◽  
Clinical Findings ◽  
Duodenal Perforation ◽  
Pathological Findings ◽  
Duodenal Papilla ◽  
Major Duodenal Papilla ◽  
Septic Peritonitis ◽  
Duodenal Perforations

The purpose of this study was to describe the clinical and gross pathological findings, treatment, and outcome in three dogs receiving deracoxib that developed proximal duodenal perforation and subsequent septic peritonitis. Clinical findings were acute vomiting and anorexia following initiation of deracoxib therapy. Deracoxib dosages ranged from 2 to 3 mg/kg per os q 24 hours. In each dog, exploratory laparotomy revealed duodenal perforations approximately 1 cm orad to the major duodenal papilla. Two out of three dogs survived following exploratory laparotomy. Two of three dogs in the present case series received the approved deracoxib dosage. Dogs receiving deracoxib, even at labeled dosages, should be monitored judiciously for signs of gastrointestinal disease.

scholarly journals Relevance of examination and treatment of the most common gastrointestinal disorders in children in Lithuania during the last decade

Medicina ◽  
2007 ◽  
Vol 44 (1) ◽  
pp. 72 ◽  
Author(s):  
Liutauras Labanauskas ◽  
Rūta Kučinskienė ◽  
Vaidotas Urbonas ◽  
Rūta Rokaitė ◽  
Neringa Libikaitė
Keyword(s):  
Duodenal Ulcer ◽  
Atopic Dermatitis ◽  
Abdominal Pain ◽  
Skin Rash ◽  
Endoscopic Examination ◽  
Gastrointestinal Disorders ◽  
Control Group ◽  
Rapid Urease Test ◽  
Urease Test ◽  
H Pylori

In the last decade, scientific studies in the field of children’s gastroenterology performed in Lithuania explored different problems: pathology of Helicobacter pylori infection and food allergy. Our studies Helirevealed that children with atopic dermatitis had gastrointestinal complaints (abdominal pain, diarrhea, distension and unstable stool, which appeared with the exacerbation of skin rash) more often as compared to nonallergic children of the control group. Abdominal pain in children with atopic dermatitis with local rash was more frequent and lasted longer than in control group children, whereas children with extended rash had stools more frequently. Gastrointestinal disorders in children with atopic dermatitis statistically significantly did not depend on the extent of skin rash and severity of atopic dermatitis. In our scientific research on the importance of H. pylori infection on children’s gastrointestinal system, children with chronic dyspepsia were examined. Endoscopy, rapid urease test, biopsies from antrum and corpus of stomach and their histological examination as well as serologic tests were done. According to the results obtained, we recommend to examine children with chronic dyspepsia in a complex way: not only endoscopic examination, but H. pylori diagnostic tests should be performed as well. Serologic test is not suitable for screening H. pylori infection in children. Considering this, we recommend to use no fewer than two different methods to diagnose this infection. The highest frequency of H. pylori infection was found in children with duodenal ulcer; histological changes in their gastric pylorus and corpus mucosa were greatest. More than half of children with nonulcer dyspepsia were infected with H. pylori. After eradication of H. pylori infection, the prevalence of dyspepsia in children with duodenal ulcer decreased.

scholarly journals Prevalence of Helicobacter pylori among patients with different gastrointestinal disorders in Saudi Arabia

2017 ◽  
Vol 25 (4) ◽  
pp. 214-20 ◽  
Author(s):  
Mohammed S. Alhussaini
Keyword(s):  
Duodenal Ulcer ◽  
Helicobacter Pylori ◽  
Saudi Arabia ◽  
Strong Association ◽  
Endoscopic Examination ◽  
Rapid Urease Test ◽  
Microscopical Examination ◽  
Increased Risk ◽  
Urease Test ◽  
H Pylori

Background: Helicobacter pylori is an important gastrointestinal pathogen associated with gastritis, peptic ulcers, and an increased risk of gastric carcinoma. The present study was carried out to determine the relationship between this organism with different gastrointestinal ailments.Methods: 150 outpatients referrals to Saudi Arabian Medical City, Riyadh, Kingdom of Saudi Arabia was recruited in January to June 2015. Each patient was subjected to endoscopic examination. Biopsy specimens were taken from the stomach for rapid urease test and culture. Suspected H. pylori colonies were subjected to colony morphology identification, microscopical examination and biochemical reactions. The samples were also subjected to PCR to detect ureA subunit of urease gene.Results: The endoscopic examination of patients revealed normal, gastric ulcer, duodenal ulcer, gastritis, and gastric cancer with a rate of 20.7%, 20%, 24%, 33.3%, and 2%, respectively. Direct smear exam revealed that 52% of patients were H. pylori positive while culture and rapid urease test showed a prevalence of 71.33%. Fifty four biopsies (36%) were urease positive after 1 hour at room temperature, 39 (62%) after 1 hour incubation at 37°C and 14 (71.33%) after 24 hours incubation. Isolated H. pylori showed that they were catalase, oxidase, and urease positive. PCR results showed 411-bp fragment, which is indicative for the ureA subunit of urease gene.Conclusion: The prevalence of H. pylori infection was high among tested population. Strong association between H. pylori and duodenal ulcer was noticed. A 411-bp fragment indicative of the ureA subunit of urease gene was detected in all the tested isolates.

Primary Gastrointestinal Lymphosarcoma with Epitheliotropism in Three Shar-Pei and One Boxer Dog

1995 ◽  
Vol 32 (4) ◽  
pp. 423-426 ◽  
Author(s):  
H. Steinberg ◽  
R. R. Dubielzig ◽  
J. Thomson ◽  
G. Dzata
Keyword(s):  
Weight Loss ◽  
Endoscopic Examination ◽  
Gastric Ulceration ◽  
Intestinal Lymphoma ◽  
Epithelial Basement Membrane ◽  
Hepatic Involvement ◽  
Mesenteric Lymph ◽  
Small Intestinal ◽  
Neoplastic Lymphocytes ◽  
Epithelial Basement

Three male Shar-pei dogs and one female spayed Boxer dog ranging in age from 4 years, 4 months to 7 years, 8 months had 4-7-week histories of diarrhea, progressive anorexia, weight loss, and vomiting. The dogs were depressed, lethargic, and hypoalbuminemic, with losses of 23-39% of body weight. Endoscopic examination revealed gastric ulceration with areas of mucosal hyperemia and pallor. Small nodules with occasional central depressions were present in three dogs. Gastric and proximal duodenal mucosal biopsies showed neoplastic lymphocytes infiltrating the lamina propria, with invasion of the superficial and glandular epithelial basement membrane. Immunohistochemical evaluation of two dogs was negative for anti-canine IgG and positive for anti-CD3. Necropsy of the Boxer and two Shar-peis confirmed epitheliotropic gastric and small intestinal lymphoma in all three dogs, with mesenteric lymph node and hepatic involvement in two and one dog, respectively.

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