scholarly journals Retrospective study of livestock vaccine coverage and trend in Lemu and Bilbilo Woreda, Arsi Zone, Ethiopia

2021 ◽  
pp. 144-150
Author(s):  
Feyisa Debele Hordofa ◽  
kedir Meseret ◽  
Shene Leta
Keyword(s):  
Skin Disease ◽  
Total Population ◽  
Vaccine Coverage ◽  
Secondary Data ◽  
Veterinary Clinic ◽  
Lumpy Skin Disease ◽  
Rate Of Spread ◽  
Arsi Zone ◽  
Control And Prevention ◽  
Gumboro Disease

Vaccination is one of the most efficient tools for protection against clinical disease of livestock and reduces the rate of spread of infection. The study was conducted using secondary data that recorded at Lemu and Bilbilo Woreda veterinary clinic with the objective to assess the vaccination coverage in the study area from March to September 2021. Results revealed the most commonly practiced vaccine were bacterial and viral diseases from secondary data recorded were Lumpy skin disease, Black leg, Pasteurellosis, New castle, Gumboro disease, chicken pox, Fowl pox, and Fowl Cholera. The percentage of vaccine coverage for lumpy skin disease decreases from a year 2017 (51.1%) to 2021(24%). The majority of Goat (96.7%) was vaccinated against goat pox during 2017 and the 0% Anthrax vaccine for Goat in 2021. Only 7.3% sheep in 2017 and near 37.4% in 2021 were vaccinated with sheep pox from total population. About 87.4% of equines were vaccinated from total population in 2017. The proportion of Newcastle disease and Gumboro disease vaccine coverage were 35% and 15.4%, respectively. Dog vaccination against rabies is increases from a year 2017 (4.8%) to 2020 (11%) in except 0.5% in 2021. The vaccine trends were fluctuating and/or decreasing from year to year. However, vaccine trend for Anthrax of cattle was increasing from year to year. It is therefore, suggested that implementation of planed and regularly vaccination of animal was very important for diseases control and prevention are recommended in order to decrease disease reoccurrence in the area.

scholarly journals Lumpy skin disease in cattle: Frequency of occurrence in a dairy farm and a preliminary assessment of its possible impact on Egyptian buffaloes

2017 ◽  
Vol 84 (1) ◽  
Author(s):  
Mahmoud M. Elhaig ◽  
Abdelfattah Selim ◽  
Mohamed Mahmoud
Keyword(s):  
Skin Disease ◽  
Clinical Signs ◽  
Dairy Farm ◽  
Skin Lesions ◽  
Epidemiological Studies ◽  
Bubalus Bubalis ◽  
Pcr Assay ◽  
Lumpy Skin Disease ◽  
Control And Prevention ◽  
Polymerase Chain

Lumpy skin disease (LSD) is an endemic infectious disease of cattle in Egypt. This survey aimed to define the prevalence of clinical and sub-clinical LSD virus (LSDV) infection among cattle and investigate their contact with water buffaloes (Bubalus bubalis) in order to improve the understanding of LSD epidemiology. Cattle and buffalo were examined owing to the appearance of skin lesions. Because clinical signs were consistent with LSDV infection, samples from cattle in a non-grazing dairy farm (n = 450) were submitted for LSDV testing together with those from the in-contact buffaloes (n = 100). Results revealed that the intra-herd percentage of cattle infected with LSDV varied with the detection method. This ranged from 22.4% to 65.4% by virus isolation (VI) and polymerase chain reaction (PCR), respectively, in clinical cattle samples, compared to 0% and 10% by VI and PCR in non-clinical cases. Using the neutralising index (NI), LSDV antibodies were found in 100% (n = 100) of the tested cow’s sera (NI = > 2.0 and ≥ 3.0), whereas buffalo’s sera (n = 34) displayed little increase in antibody level (NI ≥ 1.5). None of the buffalo were positive for LSDV by VI and PCR. In addition, there were no significant differences in LSD prevalence among the cattle with regard to age and sex. In conclusion, the occurrence of LSD in cattle warrants a further epidemiological study of the spread of the disease in the area and adoption of control and prevention strategies. In addition, the PCR assay was confirmed to be useful in the diagnosis of LSDV and for wider epidemiological studies.

Pengaruh Kinerja Keuangan dan Good Corporate Governance (GCG) Terhadap Nilai Perusahaan

MBIA ◽  
2019 ◽  
Vol 17 (2) ◽  
pp. 1-10
Author(s):  
Rolia Wahasusmiah
Keyword(s):  
Corporate Governance ◽  
Firm Value ◽  
Sampling Method ◽  
Total Population ◽  
Annual Report ◽  
Stock Exchange ◽  
Secondary Data ◽  
Positive Influence ◽  
Manufacturing Companies ◽  
Good Corporate Governance

This study aims to determine the effect of financial performance and good corporate governance (GCG) on the value of companies in manufacturing companies listed on the stock exchange Indonesia. The type of data used is secondary data in the form of annual report 2016. Population used in this study are all companies listed on the Indonesia Stock Exchange (BEI). This research uses purposive sampling method with total population of 144 companies and sample of 31 companies. The results show that simultaneously ROA, OPM, NPM, KM, and KI have a positive influence on firm value. While partially ROA  have a positive influence on firm value. While OPM, NPM, KM, and KI have no positive influence on firm value).

scholarly journals Comparative Evaluation of Lumpy Skin Disease Virus-Based Live Attenuated Vaccines

Vaccines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 473
Author(s):  
Andy Haegeman ◽  
Ilse De Leeuw ◽  
Laurent Mostin ◽  
Willem Van Campe ◽  
Laetitia Aerts ◽  
...  
Keyword(s):  
Disease Virus ◽  
Skin Disease ◽  
Vaccination Campaign ◽  
Ease Of Use ◽  
Vaccine Failure ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus ◽  
The Balkans ◽  
The Past ◽  
Preventative Strategy

Vaccines form the cornerstone of any control, eradication and preventative strategy and this is no different for lumpy skin disease. However, the usefulness of a vaccine is determined by a multiplicity of factors which include stability, efficiency, safety and ease of use, to name a few. Although the vaccination campaign in the Balkans against lumpy skin disease virus (LSDV) was successful and has been implemented with success in the past in other countries, data of vaccine failure have also been reported. It was therefore the purpose of this study to compare five homologous live attenuated LSDV vaccines (LSDV LAV) in a standardized setting. All five LSDV LAVs studied were able to protect against a challenge with virulent LSDV. Aside from small differences in serological responses, important differences were seen in side effects such as a local reaction and a Neethling response upon vaccination between the analyzed vaccines. These observations can have important implications in the applicability in the field for some of these LSDV LAVs.

scholarly journals Development of a Safe and Highly Efficient Inactivated Vaccine Candidate against Lumpy Skin Disease Virus

Vaccines ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 4
Author(s):  
Janika Wolff ◽  
Tom Moritz ◽  
Kore Schlottau ◽  
Donata Hoffmann ◽  
Martin Beer ◽  
...  
Keyword(s):  
Skin Disease ◽  
Animal Health ◽  
Vaccine Virus ◽  
Lumpy Skin Disease ◽  
Virus Shedding ◽  
Clinical Protection ◽  
Inactivated Vaccines ◽  
Disease Free ◽  
World Organisation ◽  
Free Status

Capripox virus (CaPV)-induced diseases (lumpy skin disease, sheeppox, goatpox) are described as the most serious pox diseases of livestock animals, and therefore are listed as notifiable diseases under guidelines of the World Organisation for Animal Health (OIE). Until now, only live-attenuated vaccines are commercially available for the control of CaPV. Due to numerous potential problems after vaccination (e.g., loss of the disease-free status of the respective country, the possibility of vaccine virus shedding and transmission as well as the risk of recombination with field strains during natural outbreaks), the use of these vaccines must be considered carefully and is not recommended in CaPV-free countries. Therefore, innocuous and efficacious inactivated vaccines against CaPV would provide a great tool for control of these diseases. Unfortunately, most inactivated Capripox vaccines were reported as insufficient and protection seemed to be only short-lived. Nevertheless, a few studies dealing with inactivated vaccines against CaPV are published, giving evidence for good clinical protection against CaPV-infections. In our studies, a low molecular weight copolymer-adjuvanted vaccine formulation was able to induce sterile immunity in the respective animals after severe challenge infection. Our findings strongly support the possibility of useful inactivated vaccines against CaPV-infections, and indicate a marked impact of the chosen adjuvant for the level of protection.

Development of an inactivated combined vaccine for protection of cattle against Lumpy skin disease and Bluetongue viruses

2021 ◽  
pp. 109046
Author(s):  
Youness Es-sadeqy ◽  
Zahra Bamouh ◽  
Abderrahim Ennahli ◽  
Najete Safini ◽  
Soufiane El Mejdoub ◽  
...  
Keyword(s):  
Skin Disease ◽  
Lumpy Skin Disease ◽  
Combined Vaccine

scholarly journals Production of small ruminant morbillivirus, rift valley fever virus and lumpy skin disease virus in CelCradle™ -500A bioreactors

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Halima Rhazi ◽  
Najete Safini ◽  
Karima Mikou ◽  
Meryeme Alhyane ◽  
Khalid Omari Tadlaoui ◽  
...  
Keyword(s):  
Disease Virus ◽  
Skin Disease ◽  
Rift Valley ◽  
Rift Valley Fever ◽  
Rift Valley Fever Virus ◽  
Fever Virus ◽  
Valley Fever ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus ◽  
Cell Factories

Abstract Background Animal vaccination is an important way to stop the spread of diseases causing immense damage to livestock and economic losses and the potential transmission to humans. Therefore effective method for vaccine production using simple and inexpensive bioprocessing solutions is very essential. Conventional culture systems currently in use, tend to be uneconomic in terms of labor and time involved. Besides, they offer a limited surface area for growth of cells. In this study, the CelCradle™-500A was evaluated as an alternative to replace conventional culture systems in use such as Cell factories for the production of viral vaccines against small ruminant morbillivirus (PPR), rift valley fever virus (RVF) and lumpy skin disease virus (LSD). Results Two types of cells Vero and primary Lamb Testis cells were used to produce these viruses. The study was done in 2 phases as a) optimization of cell growth and b) virus cultivation. Vero cells could be grown to significantly higher cell densities of 3.04 × 109 using the CelCradle™-500A with a shorter doubling time as compared to 9.45 × 108 cells in Cell factories. This represents a 19 fold increase in cell numbers as compared to seeding vs only 3.7 fold in Cell factories. LT cells achieved modestly higher cell densities of 6.7 × 108 as compared to 6.3 × 108 in Cell factories. The fold change in densities for these cells was 3 fold in the CelCradle™-500A vs 2.5 fold in Cell factories. The titers in the conventional system and the bioreactor were not significantly different. However, the Cell-specific virus yield for rift valley fever virus and lumpy skin disease virus are higher (25 virions/cell for rift valley fever virus, and 21.9 virions/cell for lumpy skin disease virus versus 19.9 virions/cell for rift valley fever virus and 10 virions/cell for lumpy skin disease virus). Conclusions This work represents a novel study for primary lamb testis cell culture in CellCradle™-500A bioreactors. In addition, on account of the high cell densities obtained and the linear scalability the titers could be further optimized using other culture process such us perfusion.

scholarly journals Lumpy skin disease in Kazakhstan

2021 ◽  
Vol 53 (1) ◽  
Author(s):  
Mukhit B. Orynbayev ◽  
Raikhan K. Nissanova ◽  
Berik M. Khairullin ◽  
Arman Issimov ◽  
Kunsulu D. Zakarya ◽  
...  
Keyword(s):  
Disease Virus ◽  
Cell Cultures ◽  
Skin Disease ◽  
Stomoxys Calcitrans ◽  
Lumpy Skin Disease ◽  
Dermacentor Marginatus ◽  
The Third ◽  
Gpcr Gene ◽  
Mdbk Cells ◽  
The Republic

AbstractThis study describes the registration of the first cases of lumpy skin disease in July 2016 in the Republic of Kazakhstan. In the rural district of Makash, Kurmangazinsky district of Atyrau region, 459 cattle fell ill and 34 died (morbidity 12.9% and mortality 0.96%). To determine the cause of the disease, samples were taken from sick and dead animals, as well as from insects and ticks. LSDV DNA was detected by PCR in all samples from dead animals and ticks (Dermacentor marginatus and Hyalomma asiaticum), in 14.29% of samples from horseflies (Tabanus bromius), and in one of the samples from two Stomoxys calcitrans flies. The reproductive LSD virus was isolated from organs of dead cattle and insects in the culture of LT and MDBK cells. The virus accumulated in cell cultures of LT and MDBK at the level of the third passage with titers in the range of 5.5–5.75 log 10 TCID50/cm3. Sequencing of the GPCR gene allowed us to identify this virus as a lumpy skin disease virus.

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