scholarly journals Prevalence of cancer pain, anxiety and associated factors among patients admitted to oncology ward, Tikur Anbessa Specialized Hospital, Ethiopia, 2019

2020 ◽  
Vol 4 (1) ◽  
pp. 009-017
Author(s):  
Wurjine Teshome Habte ◽  
Goyteom Mekonnen Haftom
Keyword(s):  
Cancer Pain ◽  
Associated Factors ◽  
Pain Anxiety ◽  
Specialized Hospital ◽  
Tikur Anbessa Specialized Hospital ◽  
Oncology Ward ◽  
Prevalence Of Cancer

scholarly journals Identification and Resolution of Drug-Related Problems among Childhood Cancer Patients in Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Malede Berihun Yismaw ◽  
Haileyesus Adam ◽  
Ephrem Engidawork
Keyword(s):  
Addis Ababa ◽  
Tertiary Care ◽  
Drug Dose ◽  
Morbidity And Mortality ◽  
Care Hospital ◽  
Drug Related Problems ◽  
Pediatric Hematology ◽  
Specialized Hospital ◽  
Tikur Anbessa Specialized Hospital ◽  
Oncology Ward

Background. Even though medications play a major role in the cure, palliation, and inhibition of disease, they also expose patients to drug-related problems. Drug-related problems are frequent and may result in reduced quality of life, morbidity, and mortality. Objectives. The study was aimed to identify, characterize, and resolve drug-related problems in the Pediatric Hematology/Oncology ward of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods. A prospective observational study was conducted from 25 June to 25 October 2018 to assess DRPs on patients admitted at the pediatric hematology/oncology ward of Tikur Anbessa Specialized Hospital, which is the highest level governmental tertiary care hospital in Ethiopia. Data were obtained from patients’ medical charts, physicians, patients/caregivers, pharmacists, and nurses. All the collected data were entered and analyzed using the Statistical Package for the Social Sciences version 25e. Descriptive statistics were used to represent the data. Results. Among the total 156 participants, DRPs were identified in 68.6% of the study subjects. Dosing problems which include dosage too low and high were the top ranking (39.3%) of all DRPs followed by needs additional therapy (27.2%) and nonadherence (14.0%). Systemic anti-infectives were the most common class of drugs involved in DRPs. Trimethoprim-sulfamethoxazole, methotrexate, vincristine, ondansetron, and metoclopramide were frequently involved in DRPs. The addition of drugs and change in drug dose were the two most proposed intervention types. Among the proposed interventions, 223 (92.15%) were fully accepted, 9 (3.72%) partially accepted, and 10 (4.13%) not accepted. Conclusion. DRPs are common among Pediatric Hematology/Oncology ward patients. The hospital should develop a pediatric dosing chart for the commonly prescribed medications to prevent drug-related morbidity and mortality. The integration of clinical pharmacists can mitigate risks associated with DRPs.

scholarly journals Cognitive Functioning and its Associated Factors among Breast Cancer Patients on Chemotherapy at Tikur Anbessa Specialized Hospital, Addis Ababa Ethiopia: An Institution-Based Comparative Cross-Sectional Study

2021 ◽  
Author(s):  
Edgeit Abebe ◽  
Tesfaye Tollesa ◽  
Mathewos Assefa ◽  
Zelalem Tilahun ◽  
Yohannes Dinku ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cognitive Functioning ◽  
Cancer Patients ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Breast Cancer Patients ◽  
Sectional Study ◽  
Cross Sectional ◽  
Specialized Hospital ◽  
Tikur Anbessa Specialized Hospital

Abstract Background: Breast cancer is the second leading cause of cancer in the world. It is the commonest type of cancer in Ethiopia. Cognitive problems are common among breast cancer patients especially if they are treated with chemotherapy. The study aimed to assess cognitive functioning and its associated factors among breast cancer patients at Tikur Anbessa Specialized Hospital, Ethiopia 2020.Methods: Institution-based comparative cross-sectional study was conducted. Study subjects were 117 breast cancer patients on chemotherapy and 117 women without breast cancer who volunteered for the study. Data was collected from May - June 2020. The Mini-mental status exam was used to assess cognitive functioning. Data was entered into Epi Data version 4.6.0.2 and analyzed using STATA software version 14. Univariable and multivariable linear regression model was fitted to identify factors associated with cognitive functioning. A two-tailed p-value lower than 0.05 was used to declare statistical significance.Results: Significant difference in the MMSE score was observed among breast cancer patients and controls (19.76 ±5.29, 25.18±4.68 p< 0.0001) respectively. In multivariable linear regression analysis being non-breast cancer (controls) (std.β 3.34, 95% CI [1.92 4.76] p<0.001), hemoglobin gm/dl (std. β 0.34, 95 % CI [0.04 0.63] p=0.02), and primary education (Adj. β 2.98 95 %CI [1.16 4.96] p=0.001) secondary level and more education (std. β 5.47, 95 %CI [3.51 7.28] p<0.001) were significantly associated with MMSE cognitive score. Conclusion: Breast cancer patients had lower mean MMSE scores when compared to non-breast cancer controls. Hemoglobin level, breast cancer status, and educational level are significant predictors of the MMSE cognitive score. Clinicians should incorporate routine screening of cognitive functioning for breast cancer patients and further study is required to evaluate cognitive impairment among breast cancer patients in Ethiopia.

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