Anti-oxidant Activity of Phenolic Compounds and Simultaneous Contents Determination using HPLC-UV from the Akebiae caulis

Background: Plants are frequently used by traditional healer for the care of the hepatic pathologies.Objective: This study is part of the valorization of the hepatoprotective potential of some plants used in traditional medicine for the care of hepatitis in the Hauts-Bassins region of Burkina Faso.Materials and methods: A survey realized in this region allowed retaining 5 species, after the classification according to the frequency of quotation and the bibliographic review, among the 44 species recorded: Anogeissus leiocarpus (DC.) Guill. & Perr (Combretaceae), Balanites aegyptiaca Delie. (Balanitaceae), Cassia alata L. (Ceasalpiniaceae), Opilia celtidifolia (Guill. & Perr.) Endl. (Opiliaceae) and Ziziphus mauritiana L. (Rhamnaceae). The content in phenolic compounds of the aqueous extracts of these plants was determined. Their antioxidant activity was evaluated by two methods: discoloration of radical cation ABTS and iron reduction (FRAP).Results: Anogeissus leiocarpus and Ziziphu smauritiana gave the strongest antioxidant activities and high phenolic compounds (total phenolics, total flavonoids, total tannins and flavonols). The antioxidant activity (FRAP, ABTS) was associated with the total phenolic content of the extracts expressed in tannic acid equivalent per 100 grams of dry matter with R2 of 0.8148 and 0.7966.Conclusion: The antioxidant activity and the content phenolic compounds observed during this study with Anogeissus leiocarpus and Ziziphus mauritiana indicates that these two plants have a high hépato protective potential which can justify their use by the Traditional healer in the care of hepatitis.

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The Pavonia xanthogloea (Ekman, Malvaceae): Phenolic compounds quantification, anti-oxidant and cytotoxic effect on human lymphocytes cells

Pharmacognosy Magazine ◽

10.4103/0973-1296.139804 ◽

2014 ◽

Vol 10 (39) ◽

pp. 630 ◽

Cited By ~ 1

Author(s):

IvanaBeatrice Mânica da Cruz ◽

ClaricePinheiro Mostardeiro ◽

MarcoAurélio Mostardeiro ◽

AdemirFarias Morel ◽

RaulMoreira Oliveira ◽

...

Keyword(s):

Phenolic Compounds ◽

Cytotoxic Effect ◽

Human Lymphocytes ◽

Anti Oxidant

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Phenolic compounds from the stems of Fissistigma polyanthoides and their anti-oxidant activities

Fitoterapia ◽

10.1016/j.fitote.2019.104252 ◽

2019 ◽

Vol 137 ◽

pp. 104252 ◽

Cited By ~ 2

Author(s):

Hieu Nguyen Ngoc ◽

Lisa Mair ◽

Duc Trong Nghiem ◽

Kim Le Thien ◽

Johanna M. Gostner ◽

...

Keyword(s):

Phenolic Compounds ◽

Anti Oxidant

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Solid Lipid Nanoparticles as Carriers of Natural Phenolic Compounds

Antioxidants ◽

10.3390/antiox9100998 ◽

2020 ◽

Vol 9 (10) ◽

pp. 998

Author(s):

Alexandra Borges ◽

Victor de Freitas ◽

Nuno Mateus ◽

Iva Fernandes ◽

Joana Oliveira

Keyword(s):

Phenolic Compounds ◽

Solid Lipid Nanoparticles ◽

Biological Effects ◽

Lipid Nanoparticles ◽

Promising Technique ◽

Major Drawback ◽

Preparation Methods ◽

Solid Lipid ◽

Anti Oxidant ◽

Natural Phenolic Compounds

Phenolic compounds are one of the most widespread classes of compounds in nature, with several beneficial biological effects being associated with their anti-oxidant and anti-carcinogenic activities. Their application in the prevention or treatment of numerous chronic diseases have been studied, but a major drawback is still the low bioavailability of these compounds, as well as their instability towards pH, temperature, and light in some cases. Nanotechnology has emerged as an alternative to overcome these limitations, and the use of lipidic encapsulation systems is a promising technique to achieve an efficient drug delivery, protecting molecules from external factors and improving their bioavailability. In this review, solid lipid nanoparticles and nanostructured lipid carriers are highlighted as an important tool for the improvement of the bioavailability and stability of natural phenolic compounds, including their preparation methods and functionalization approaches and the discussion of several applications for putative use in cosmetic and pharmacologic products.

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Nutraceutical Analysis of Marticaria recutita (Chamomile) Dried Leaves and Flower Powder and Comparison between Them

International Journal of Phytomedicine ◽

10.5138/09750185.2249 ◽

2018 ◽

Vol 10 (2) ◽

pp. 111

Author(s):

Ekta Singh Chauhan ◽

Jaya Aishwarya

Keyword(s):

Phenolic Compounds ◽

Vitamin C ◽

Bioactive Compounds ◽

Aqueous Extract ◽

Nutrient Content ◽

Different Types ◽

Anti Oxidant ◽

Chamaemelum Nobile ◽

Anti Inflammatory

Chamomile is known as German Chamomile (Marticaria recutita) and Roman Chamomile (Chamaemelum nobile) a very famous daisy plant. The work mainly focuses on the nutraceuticals potential of Chamomile leaf and flower of this plant. The nutrient contains of the leaf and flower power was determined by various methods. The phytochemicals screening of the leaf and flower aqueous extract was performed by the different procedure. Leaf of this plant is rich in carbohydrate, protein, fat and also rich in vitamin C, iron, zinc and calcium. Whereas flower is rich in moisture and fiber as compared to leaf. The aqueous extract of leaf of Chamomile showed the presence of steroids, terpenoids, flavonoids, tannins and saponins and flower were lacked in alkaloids, saponins, gelatin and phenolic compounds. The results record that leaf and flowers powder contains different types of nutrients and phytochmicals in it. Chamomile is rich in different bioactive compounds, antioxidant and phytochemicals; carries many pharmacological and traditional properties. Leaves, flowers and stems of Chamomile are used as anti-oxidant, analgesic, anti-viral, anti-inflammatory, anti-septic, anti-diabetic, anti-proliferative, anti-bacterial activities and many more diseases. This paper put a light on nutrient content and phytochemical properties of Chamomile leaf and flower.

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Optimizing the Extraction of Phenolic Compounds with High Anti-oxidant Activity from Mango Seed Kernel Wastes Using Response Surface Methodology

Applied Environmental Research ◽

10.35762/aer.2020.42.3.6 ◽

2020 ◽

pp. 60-76

Author(s):

Francis Dave C. Siacor ◽

Camila Flor Y. Lobarbio ◽

Evelyn B. Taboada

Keyword(s):

Response Surface Methodology ◽

Phenolic Compounds ◽

Response Surface ◽

Ethanol Concentration ◽

Seed Kernel ◽

Extraction Temperature ◽

Positive Effects ◽

Water Solvent ◽

Anti Oxidant ◽

Mango Seed

Mango seed kernels (MSK), which are waste streams in mango processing industry, are good sources of phenolic compounds with high anti-oxidant, anti-bacterial, and anti-viral properties. These phenolic compounds are reported to have an increasing demand over the years in the quest for healthy ready-to-eat food and nutraceuticals. To recover these compounds from MSK, solid-liquid extraction (SLE) can simply be applied, although there is a knowledge gap in in the systematic exploration of this process for mango-based phenolic compounds. In this work, phenolic compounds were extracted from MSK through SLE using ethanol-water solvent system. A statistical-based approach was used to evaluate and optimize the extraction conditions in relation to yield of phenolic compounds from MSK. The central composite design together with response surface methodology was adopted to assess the effect of extraction temperature (30oC, 45oC, and 60oC) and ethanol concentration (25% – 75%) under fixed extraction time (105 min) and solid-to-solvent ratio (1:10) on the extraction yield. Both temperature and ethanol concentration provided positive effects on the yield and the following optimum conditions of temperature and ethanol concentration were obtained at 63.21oC and 53.21% ethanol, respectively. A second-order polynomial equation was obtained describing the extraction process, and a validation test of this response model showed that it sufficiently described the process. Furthermore, the extracts obtained at optimal conditions possess a potential antioxidant activity at IC50 = 45 ± 0.002 µg GAE mL-1 extract. The results indicated that phenolic compounds in MSK can be recovered through extraction using aqueous ethanol. This study also promotes value-addition of a seemingly useless waste material while reducing its health and environmental impact.

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Hidden potential of fruit waste and its utilization

Sustainability Agri Food and Environmental Research ◽

10.7770/safer-v0n0-art2213 ◽

2020 ◽

Author(s):

Damini Soni ◽

Gargi Saxena

Keyword(s):

Phenolic Compounds ◽

Bioactive Compounds ◽

Food Waste ◽

Value Chain ◽

Food Industry ◽

Food Additives ◽

Value Added ◽

Good Source ◽

Anti Oxidant ◽

By Products

The global increasing population demands for more food production and food processing which consequently results in more food waste generation. The total waste produced in different stages of processing of food generally comprises of peels, pomace, seed, pulp, unused flesh and damaged food which is biodegradable in nature. These by-products are a good source of bioactive compounds like polyphenols, antioxidants and phytochemicals. They are the storehouse of complex carbohydrates, lipids, proteins and nutraceuticals depending on the nature of product produced for example poultry and meat industries are rich the source of proteins and lipids, fruits and vegetable processing industries are rich in bioactive compounds and cereal industries are good source of phenolic compounds and dietary fiber. The food waste or by-products are important source of colorants, fiber, flavoring and antimicrobials which are used in food industry as a source of food additives. The phenolic compounds present in by products of different foods exhibit anti-oxidant, anti-microbial, anti-inflammatory, immune-modulatory activity and play a major role in reducing the risk of cardiovascular problems, osteoporosis, thrombosis, platelets aggregation and diabetes in humans. By products from different industries can be used to develop value added products in India where poverty and malnutrition are the major issues. Developing effective policies for the utilization of food waste along the value chain can help reduce food waste problem and contribute towards food security and sustainability.Keywords: By products, Bioactive compounds, Food industry, Food waste.

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