scholarly journals PRIMEROS EPISODIOS PSICÓTICOS INDUCIDOS POR CANNABIS Y SU EVOLUCIÓN A ESQUIZOFRENIA

2021 ◽  
Author(s):  
Mª Carmen Martin ◽  
Diego Remón ◽  
Carolina Lorenzo ◽  
Juan Matías ◽  
Jose Antonio Benito ◽  
...  
Keyword(s):  
Clinical Interview ◽  
Dsm 5 ◽  
Syndrome Scale ◽  
Consumo De Sustancias ◽  
Negative Syndrome

Introducción: Existen pocos estudios que ayuden a encontrar diferencias entre los trastornos psicóticos inducidos por cannabis y los pacientes con esquizofrenia que consumen cannabis. Siendo el límite de ambas entidades, muy difuso. De hecho, son muchos los pacientes que inicialmente son diagnosticados de Trastorno Psicótico inducido por cannabis, y acaban padeciendo de Esquizofrenia. Objetivos: Estudiar las características clínicas asociadas a los primeros episodios de psicosis por consumo de cannabis y su evolución, y encontrar, si las hubiera, diferencias con las psicosis que debutan sin estar relacionadas con el consumo de sustancias. Material y métodos: La muestra incluye 35 pacientes, que requirieron ingreso en la Unidad de Hospitalización Breve del Complejo Asistencial Universitario de Salamanca (CAUSA) por presentar un Primer Episodio Psicótico (PEP). Se han incluido pacientes mayores de 18 años, con diagnóstico clínico de PEP, sin relación con consumo de sustancias y los inducidos por cannabis, excluyendo aquellos que se produjeron en el contexto de consumo de otras sustancias. Los sujetos han sido evaluados con la Structured Clinical Interview for the DSM-5, se recogieron datos sociodemográficos, se realizaron pruebas complementarias y todos los pacientes se evaluaron con la Escala de Síndrome Positivo y Negativo (The Positive and Negative Syndrome Scale PANSS). Esta evaluación se realizó en varios momentos de la hospitalización. Cuando la situación cínica lo permitió, fueron evaluados también con una batería neurocognitiva. Posteriormente, se ha observado, en un período máximo de 5 años, su evolución o no, a Esquizofrenia. Resultados y conclusiones: SÍ parecen existir diferencias clínicas entre los PEP inducidos por cannabis y los que no están relacionados con el consumo de sustancias; en la evolución temprana y en la duración de las hospitalizaciones. Nos surgen dudas sobre la fiabilidad y utilidad de las categorías diagnósticas.

Swedish experiences with the structured clinical interview for the positive and negative syndrome scale for schizophrenia (SCI-PANSS)

1994 ◽  
Vol 9 (3) ◽  
pp. 145-147 ◽  
Author(s):  
L von Knoiring ◽  
E Lindstrüm
Keyword(s):  
19Th Century ◽  
Negative Symptoms ◽  
Clinical Interview ◽  
Positive Symptoms ◽  
Diagnostic Systems ◽  
Syndrome Scale ◽  
Negative Syndrome ◽  
First Rank Symptoms ◽  
The 19Th Century

Already at the end of the 19th century, Hughlings-Jackson suggested that positive symptoms such as hallucinations and delusions should be kept apart from negative symptoms such as anhedonia and reduced energy in all psychoses. Both Kreapelin and Bleuler regarded the negative symptoms as fundamental in schizophrenia while the positive symptoms were regarded as being accessory, accompanying the disorder. This view was maintained for 60 years (table 1) until Schneider (1959) introduced the “first rank symptoms”, all of them positive. Schneider never advocated that these symptoms should be a sufficient basis for a diagnosis of schizophrenia. In any case, the “first rank Symptoms” have been included in most later diagnostic systems (table 1).

scholarly journals Personality traits of Lebanese patients with schizophrenia: Comparison by gender and severity of psychosis

2019 ◽  
Author(s):  
Joseph E Dib ◽  
Chadia Haddad ◽  
Ilige Nehme ◽  
Jocelyne Azar ◽  
Ghina Al Seddik ◽  
...  
Keyword(s):  
Personality Traits ◽  
Personality Trait ◽  
Healthy Subjects ◽  
Psychotic Symptoms ◽  
Healthy Individuals ◽  
Healthy Group ◽  
Dsm 5 ◽  
Syndrome Scale ◽  
Schizophrenic Patients ◽  
Negative Syndrome

Abstract Objectives Schizophrenia is known as a mental disease affecting how an individual will reply to a certain scenario in a way that differs from a person to another. A specific personality trait can influence the expressions of psychotic symptoms and affect illness courses. Our aim during this study was to spot nonadaptive personality traits in Lebanese Schizophrenic patients and compare them to healthy subjects.Methods We took a pair of teams one schizophrenic individuals (n=250) and the other healthy individuals (n=250). For the data assortment the tools used were: personality inventory for the DSM-5 (PID-5-BF) brief type, to assess the maladaptive personality traits; Positive and Negative Syndrome Scale (PANSS), to determine the severity of psychotic symptoms in schizophrenic individuals.Results The results were a considerably higher mean in detachment, antagonism and psychoticism personality traits in schizophrenic subjects compared to healthy group. When comparing personality based on the gender a considerably higher mean of negative affect and psychoticism was found in women compared to men, as for the antagonism and detachment it had been considerably higher in men.Conclusion In conclusion, we can say that schizophrenic subjects have a particular personality trait totally different from the overall healthy subjects.

Factor Structure of the Positive and Negative Syndrome Scale (PANSS) Differs by Sex

2018 ◽  
Vol 11 (4) ◽  
pp. 207-213 ◽  
Author(s):  
Julie Walsh-Messinger ◽  
Daniel Antonius ◽  
Mark Opler ◽  
Nicole Aujero ◽  
Deborah M. Goetz ◽  
...  
Keyword(s):  
Factor Structure ◽  
Syndrome Scale ◽  
Negative Syndrome

Risk factors associated with treatment-resistant schizophrenia in first-episode psychosis

2017 ◽  
Vol Ano 7 ◽  
pp. 8-12
Author(s):  
Ana Beatriz de Oliveira Assis ◽  
Jayse Gimenez Pereira Brandão ◽  
Pedro Otávio Piva Espósito ◽  
Osmar Tessari Junior ◽  
Bruno Berlucci Ortiz
Keyword(s):  
Risk Factors ◽  
First Episode Psychosis ◽  
First Episode ◽  
Treatment Resistant ◽  
Factors Associated ◽  
Syndrome Scale ◽  
Episode Psychosis ◽  
Negative Syndrome

Objetivo: Ainda não está claro quais são os fatores de risco para a esquizofrenia resistente ao tratamento (ERT) em primeiro episódio psicótico (PEP). O objetivo deste trabalho é investigar indicadores de risco para ERT em PEP. Métodos: Foram selecionados 53 pacientes em primeiro episódio psicótico, com diagnóstico de esquizofrenia, que deram entrada à enfermaria de psiquiatria do Hospital das Clínicas Luzia de Pinho Melo entre 2011 e 2015. Ao ser admitido na enfermaria, o paciente era avaliado com a Escala de Sintomas para as Síndromes Positiva e Negativa (Positive and Negative Syndrome Scale – PANSS) e recebia tratamento inicial por 4 semanas. Caso sua resposta fosse inferior a 40% de redução na PANSS, o antipsicótico era trocado, e as escalas eram aplicadas novamente após mais 4 semanas. Após a falha com dois antipsicóticos, em doses plenas, por 4 semanas cada, a clozapina era introduzida, e o paciente era considerado ERT. Uma regressão logística foi aplicada onde sexo, idade de início, tempo de doença não tratada, uso de substâncias, avaliação global do funcionamento inicial e PANSS inicial total foram inseridos como variáveis independentes, e ERT foi inserida como variável dependente. Resultados: Tempo de doença não tratada apresentou significância de p = 0,038 e Exp (B) = 4,29, enquanto que PANSS total apresentou p = 0,012 e Exp (B) = 1,06. Conclusão: Identificar os fatores associados à resistência precoce ao tratamento poderia permitir aos clínicos evitar o atraso na introdução da clozapina e prevenir um pior prognóstico para esses pacientes.

Standardized training in the rating of the six-item Positive And Negative Syndrome Scale (PANSS-6)

2021 ◽  
Vol 228 ◽  
pp. 438-446
Author(s):  
Pernille Kølbæk ◽  
David Dines ◽  
Johanna Hansen ◽  
Mark Opler ◽  
Christoph U. Correll ◽  
...  
Keyword(s):  
Syndrome Scale ◽  
Negative Syndrome

scholarly journals Amusia and protolanguage impairments in schizophrenia

2014 ◽  
Vol 44 (13) ◽  
pp. 2739-2748 ◽  
Author(s):  
J. T. Kantrowitz ◽  
N. Scaramello ◽  
A. Jakubovitz ◽  
J. M. Lehrfeld ◽  
P. Laukka ◽  
...  
Keyword(s):  
Cognitive Remediation ◽  
Thought Disorder ◽  
Musical Ability ◽  
Group Status ◽  
Treatment Development ◽  
Discrimination Ability ◽  
Syndrome Scale ◽  
Language And Music ◽  
Auditory Tasks ◽  
Negative Syndrome

BackgroundBoth language and music are thought to have evolved from a musical protolanguage that communicated social information, including emotion. Individuals with perceptual music disorders (amusia) show deficits in auditory emotion recognition (AER). Although auditory perceptual deficits have been studied in schizophrenia, their relationship with musical/protolinguistic competence has not previously been assessed.MethodMusical ability was assessed in 31 schizophrenia/schizo-affective patients and 44 healthy controls using the Montreal Battery for Evaluation of Amusia (MBEA). AER was assessed using a novel battery in which actors provided portrayals of five separate emotions. The Disorganization factor of the Positive and Negative Syndrome Scale (PANSS) was used as a proxy for language/thought disorder and the MATRICS Consensus Cognitive Battery (MCCB) was used to assess cognition.ResultsHighly significant deficits were seen between patients and controls across auditory tasks (p < 0.001). Moreover, significant differences were seen in AER between the amusia and intact music-perceiving groups, which remained significant after controlling for group status and education. Correlations with AER were specific to the melody domain, and correlations between protolanguage (melody domain) and language were independent of overall cognition.DiscussionThis is the first study to document a specific relationship between amusia, AER and thought disorder, suggesting a shared linguistic/protolinguistic impairment. Once amusia was considered, other cognitive factors were no longer significant predictors of AER, suggesting that musical ability in general and melodic discrimination ability in particular may be crucial targets for treatment development and cognitive remediation in schizophrenia.

scholarly journals Decision making under ambiguity and risk in adolescent-onset schizophrenia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Dandan Li ◽  
Fengyan Zhang ◽  
Lu Wang ◽  
Yifan Zhang ◽  
Tingting Yang ◽  
...  
Keyword(s):  
Decision Making ◽  
Executive Function ◽  
Iowa Gambling Task ◽  
Clinical Symptoms ◽  
Healthy Controls ◽  
Syndrome Scale ◽  
Significant Difference ◽  
Abnormal Pattern ◽  
Negative Syndrome ◽  
The Relationship

Abstract Objective Numerous studies have identified impaired decision making (DM) under both ambiguity and risk in adult patients with schizophrenia. However, the assessment of DM in patients with adolescent-onset schizophrenia (AOS) has been challenging as a result of the instability and heterogeneity of manifestations. The Iowa Gambling Task (IGT) and Game of Dice Task (GDT), which are frequently used to evaluate DM respectively under ambiguity and risk, are sensitive to adolescents and neuropsychiatric patients. Our research intended to examine the performance of DM in a relatively large sample of patients with AOS using the above-mentioned two tasks. We also aimed to take a closer look at the relationship between DM and symptom severity of schizophrenia. Methods We compared the performance of DM in 71 patients with AOS and 53 well-matched healthy controls using IGT for DM under ambiguity and GDT for DM under risk through net scores, total scores and feedback ration. Neuropsychological tests were conducted in all participants. Clinical symptoms were evaluated by using Positive and Negative Syndrome Scale (PANSS) in 71 patients with AOS. Pearson’s correlation revealed the relationship among total score of DM and clinical and neuropsychological data. Results Compared to healthy controls, patients with AOS failed to show learning effect and had a significant difference on the 5th block in IGT and conducted more disadvantageous choices as well as exhibited worse negative feedback rate in GDT. Apart from DM impairment under risk, diminished DM abilities under ambiguity were found related to poor executive function in AOS in the present study. Conclusions Our findings unveiled the abnormal pattern of DM in AOS, mainly reflected under the risky condition, extending the knowledge on the performance of DM under ambiguity and risk in AOS. Inefficient DM under risk may account for the lagging impulse control and the combined effects of developmental disease. In addition, our study demonstrated that the performance on IGT was related to executive function in AOS.

scholarly journals The relationship of insight with psychopathological dimensions in patients with schizophrenia

2021 ◽  
Vol 12 (2) ◽  
pp. 204380872110199
Author(s):  
Si-Sheng Huang ◽  
Cheng-Chen Chang
Keyword(s):  
Medical Center ◽  
Self Report ◽  
Psychiatric Ward ◽  
Neurocognitive Functions ◽  
Bivariate Correlation ◽  
Syndrome Scale ◽  
Acute Psychiatric Ward ◽  
Negative Syndrome ◽  
Relationship Of ◽  
The Relationship

Impaired insight in patients with schizophrenia results in less satisfactory clinical outcomes. This study was conducted to investigate the relationship between insight and individual psychopathological dimensions in inpatients with schizophrenia using a self-report questionnaire. In this study, 90 patients with schizophrenia aged 18–75 years admitted in the acute psychiatric ward of a medical center in Taiwan were enrolled. Patient insight was measured using the Self-Appraisal of Illness Questionnaire (SAIQ), and psychopathological dimensions were measured using the Positive and Negative Syndrome Scale (PANSS) and its five-factor structure model. A higher SAIQ score indicates greater insight. In bivariate correlation analyses, statistically significant correlations were observed between age, single marital status, educational level, and positive, excited, and depressed symptom factor of the PANSS and SAIQ score. In regression analyses, age and excited and depressed symptom factors were significantly associated with SAIQ score. No significant association was observed between insight and neurocognitive functions. Considering demographic characteristics, psychopathology, and neurocognition, in the acute phase of schizophrenia, younger patients with less severe excited symptoms and more severe depressive symptoms had greater insight.

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