Reproductive Efficiency, Milk Production, Health Status, Antioxidant Capacity, Lipid Profile, and Metabolic Hormones of Lactating Cows Treated with Coenzyme Q10 and L-Carnitine

Background and objective: Oxidative stress and inflammation are key parameters in developing metabolic disorders. Hence, antioxidant intake might be an appropriate approach. Several studies have evaluated the effect of coenzyme Q10 (CoQ10) supplementation on lipid profile among patients with metabolic diseases, though findings are controversial. The aim of this systematic review and meta-analysis was to determine the effects of CoQ10 supplementation on lipid profile in patients with metabolic disorders. Methods: We searched PubMed, EMBASE, Web of Science and Cochrane Library databases until July 2017. Prospective clinical trials were selected assessing the effect of CoQ10 supplementation on different biomarkers. Two reviewers independently assessed the eligibility of studies, extracted data, and evaluated the risk of bias of included studies. A fixed- or random-effects model was used to pool the data, which expressed as a standardized mean difference with 95% confidence interval. Heterogeneity was measured using a Q-test and with I2 statistics. Results: A total of twenty-one controlled trials (514 patients and 525 controls) were included. The meta-analysis indicated a significant reduction in serum triglycerides levels (SMD -0.28; 95% CI, -0.56, -0.005). CoQ10 supplementation also decreased total-cholesterol (SMD -0.07; 95% CI, -0.45, 0.31), increased LDL- (SMD 0.04; 95% CI, -0.27, 0.36), and HDL-cholesterol levels (SMD 0.10; 95% CI, -0.32, 0.51), not statistically significant. Conclusion: CoQ10 supplementation may significantly reduce serum triglycerides levels, and help to improve lipid profiles in patients with metabolic disorders. Additional prospective studies are recommended using higher supplementation doses and longer intervention period.

Download Full-text

Effect of Bypass Protein on Milk Production and Economic of Lactating Crossbred Cows

Journal of AgriSearch ◽

10.21921/jas.v7i01.17633 ◽

2020 ◽

Vol 7 (01) ◽

Author(s):

RATNESH K CHOUDHARY ◽

A Saran ROY ◽

N K SINGH3 ◽

SANJAY KUMAR ◽

RAUSHAN K SINGH

Keyword(s):

Milk Production ◽

Milk Yield ◽

Crossbred Cows ◽

Lactating Cows ◽

Feed Cost ◽

Total Diet ◽

T1 And T2 ◽

Daily Milk Yield ◽

On Farm ◽

Daily Milk

An On-Farm Trial was conducted on 24 lactating crossbred cows for assessment of feeding formaldehyde treated mustard cake (bypass protein) on milk production and economic analysis of lactating cow. Cows were divided into three groups having 8 cows each, treatments were farmers’ practice (FP); (Control): The lactating animals under this group were fedas per the feeding schedule of the farmers (5 kg. dry roughage as rice straw + 6 hrs grazing as local grass and 4 kg. commercial concentrates), T1: The lactating animals under this group were fed as per farmers practicewith 12% mustard cake of total diet was provided to the cow by replacing the same amount of commercial concentrates andT2: The lactating animals under this group were fed as per farmers practicewith 12% formaldehyde treated mustard cake of total diet was provided to the cow by replacing same amount of commercial concentrates. The average daily milk yield of lactating cows under FP, T1 and T2 was 8.58, 8.82 and 9.85 kg per cow, respectively. Differences between FP and T2 were significant. The daily increase in milk yield was 1.27 kg and 1.03 kg in cows fed T2diet over the cows fed FP and T1diet, respectively. The B: C ratios for FP, T1 and T2 groups were 2.6, 3.0 and 3.3, respectively. The feed cost reduced in T2 group by Rs. 8.64 and increased milk production by 1.27 kg in respect to FP group.

Download Full-text

HIGH MOISTURE GROUND EAR CORN, HIGH MOISTURE BARLEY OR SODIUM HYDROXIDE TREATED BARLEY FOR LACTATING COWS: MILK PRODUCTION AND RATION UTILIZATION

Canadian Journal of Animal Science ◽

10.4141/cjas83-018 ◽

1983 ◽

Vol 63 (1) ◽

pp. 155-162 ◽

Cited By ~ 6

Author(s):

L. KUNG Jr. ◽

B. W. JESSE ◽

J. W. THOMAS ◽

J. T. HUBER ◽

R. S. EMERY

Keyword(s):

Sodium Hydroxide ◽

Key Words ◽

Milk Production ◽

Dry Matter ◽

Milk Composition ◽

Dry Matter Intake ◽

High Moisture ◽

Acid Detergent Fiber ◽

Lactating Cows ◽

Fecal Ph

Whole barley was treated with sodium hydroxide (NaOH) in laboratory trials. Dry matter disappearance from nylon bags in the rumen of whole barley treated with 2.5, 3.5, or 4.9% NaOH for 30 h was 59.6, 72.4, and 93.0%, respectively, compared with 82.2% for untreated ground barley. In a subsequent lactation trial, 24 Holstein cows (eight per treatment) were fed high moisture ground ear corn, high moisture rolled barley or high moisture whole barley treated with 3.5% NaOH. Milk persistencies tended to be greater for cows fed high moisture rolled barley, next for ground ear corn and least for NaOH-treated barley. Milk composition was similar for all treatments. Dry matter intake was greatest for cows fed ground ear corn and lower for those fed the barley diets. Alpha-linked glucose and pH of feces were similar for cows fed ground ear corn and high moisture rolled barley diets, but fecal pH was lower and alpha-linked glucose concentrations three times greater for NaOH-treated barley. Digestibility percents of dry matter, acid detergent fiber and nitrogen were 61.4, 25.3, 64.7 for ground ear corn; 64.4, 38.0, 67.1 for high moisture rolled barley; and 56.8, 43.2, 54.8 for NaOH-treated barley, respectively. Rumen grain turnover estimated by excretion of ytterbium in feces was greatest for NaOH-treated barley (9.09%/h), intermediate for ground ear corn (6.10%/h) and lowest for high moisture rolled barley (4.93%/h). Key words: Dairy, sodium hydroxide, high moisture grains

Download Full-text

Three Times a Day Milking: Effects on Milk Production, Reproductive Efficiency, and Udder Health

Journal of Dairy Science ◽

10.3168/jds.s0022-0302(86)80553-7 ◽

1986 ◽

Vol 69 (5) ◽

pp. 1441-1446 ◽

Cited By ~ 41

Author(s):

Diana B. Allen ◽

E.J. DePeters ◽

R.C. Laben

Keyword(s):

Milk Production ◽

Reproductive Efficiency ◽

Udder Health

Download Full-text

A comparison of starchy and fibrous concentrates for milk production, energy utilization and hay intake by Friesian cows

The Journal of Agricultural Science ◽

10.1017/s0021859600080801 ◽

1987 ◽

Vol 109 (2) ◽

pp. 375-386 ◽

Cited By ~ 77

Author(s):

J. D. Sutton ◽

J. A. Bines ◽

S. V. Morant ◽

D. J. Napper ◽

D. J. Givens

Keyword(s):

Milk Production ◽

Milk Yield ◽

Live Weight ◽

Metabolizable Energy ◽

Energy Utilization ◽

Energy Yield ◽

Carbohydrate Source ◽

Lactating Cows ◽

Concentrate Inclusion ◽

Friesian Cows

SummaryTwenty-four Friesian cows were allocated to one of four diets for weeks 3–14 of lactation following 2 weeks on a common diet. The diets (kg air-dry feed/day) were 7–2 kg hay and 10·8 kg either starchy or fibrous concentrates (60S and 60F) or 3·5 kg hay and 14·0 kg either starchy or fibrous concentrates (80S and 80F). Rumen samples were taken by stomach tube in weeks 10 and 12 of lactation and the digestibility of the diets was measured with four cows per treatment during weeks 13 and 14. The digestibility of the same feeds was also measured in sheep at maintenance.The principal carbohydrate constituents of the concentrates were barley, wheat and cassava in the starchy concentrates and citrus pulp, sugar-beet pulp and wheat feed in the fibrous concentrates. The concentrates were designed to have similar concentrations of metabolizable energy (ME) and the diets were planned to provide similar intakes of digestible energy and crude protein.Milk yield and composition were very similar for treatments 60S and 60F. With the higher proportion of starchy concentrates (80S), milk yield was about 20% greater than on 60S, fat concentration fell severely but protein and lactose concentrations were unaffected. With the higher proportion of fibrous concentrates (80F), milk yield and the protein and lactose concentration were similar to values on 60F but fat concentration was lower, though not nearly so low as on 80S. Milk energy yield was reduced by the higher proportion of concentrates but was unaffected by type of carbohydrates. Live-weight changes were small.In both the sheep, consuming at maintenance, and the lactating cows consuming at about 3 times maintenance, digestibility of dry matter, organic matter and energy was higher with the higher concentrate diets but was unaffected by type of concentrate. The digestibility of fibre was greater with the fibrous concentrates but the effect of level of concentrate inclusion was inconsistent. Digestibility coefficients were consistently lower for the lactating cows than for the sheep.The proportion of acetic acid in the rumen volatile fatty acids in the cows was higher and the proportion of propionic acid was lower with the fibrous concentrates. The differences were much greater with the higher proportion of concentrates.During weeks 15–22 of lactation the cows were reallocated to concentrate treatments and given hay ad libitum. Hay intake was about 1 kg/day higher with the fibrous concentrates but the difference was not significant. Hay intake fell by about 0·6 kg/kg concentrate intake for both concentrate types. No significant differences in milk yield or composition were established, probably because of incomplete adaptation even after 8 weeks.It is concluded that at concentrate intakes of about 10 kg/day, the source of carbohydrate in the concentrates has little effect on milk production when the concentrates are of similar ME concentration. However, at higher levels of concentrate inclusion, although the diets may have similar ME concentrations, important differences in the yields of fat, protein and lactose occur due to carbohydrate source and these can be related to differences in rumen fermentation.

Download Full-text

Coenzyme q10 is potentially usedto improve lipid profile in diabetic hypercholesterolemia-induced periodontitis in the coastal area

E3S Web of Conferences ◽

10.1051/e3sconf/20184707006 ◽

2018 ◽

Vol 47 ◽

pp. 07006

Author(s):

Saryono Saryono ◽

Hesti Devinta ◽

Abdul Haris Budi Widodo ◽

Arif Imam Hidayat

Keyword(s):

Lipid Profile ◽

Coenzyme Q10 ◽

Coastal Area ◽

Positive Control ◽

Atherogenic Index ◽

Control Group ◽

Treatment Groups ◽

Significant Difference ◽

Pap Method ◽

Post Hoc

Contaminated water often affects the occurrence of periodontitis in the coastal area. The diabetic hypercholesterolemia-induced periodontitis in Indonesia is very high. The use of coenzyme Q10 to treat this disease has never been investigated yet. Therefore, this study aimedto analyze the effect of coenzyme Q10 on the lipid profile of diabetic hypercholesterolemia-induced periodontitis.Twenty four rats were randomized into 6 groups (G1-G6). The groups (G1-G3) are healthy, negative and positive control group respectively. The treatment groups (G4-G6) are diabetic hypercholesterolemia-induced rats given coenzyme q10 dose of 13,5; 27 and 54 mg/kg respectively. Rats were induced by periodontitis, hypercholesterolemia and diabetes mellitus. Coenzyme Q10 was administered orally using 2 mL gastric tube once a day for 14 days. Lipid profile including triglycerides, HDL, and atherogenic index (IA) was measured enzymatically by the CHOD-PAP method. Data were analyzed by one-way ANOVA test and followed by the Least Significant Difference (LSD) post hoc test.Coenzyme Q10 with a dose of 54 mg/kgis effective in lowering triglyceride, and atherogenic index and increasing HDL level in diabetic hyperlipidemia-induced periodontitis rats model. This research supports the potential effects of coenzyme Q10 supplementation to improve lipid profile in diabetic hypercholesterolemia-induced periodontitis in the coastal area.

Download Full-text

Cost Effectiveness of Feeding Chelated Zinc on Milk Production in Lactating Cows

International Journal of Current Microbiology and Applied Sciences ◽

10.20546/ijcmas.2020.906.148 ◽

2020 ◽

Vol 9 (6) ◽

pp. 1191-1196

Author(s):

Roshan Rajesh ◽

S. Senthilkumar ◽

P. C. Sakthivel ◽

N. Muthusamy ◽

A. Natarajan ◽

...

Keyword(s):

Cost Effectiveness ◽

Milk Production ◽

Lactating Cows

Download Full-text

Performance and blood parameters of Holstein/Zebu crossbred heifers fed with two tannins sources

Research Society and Development ◽

10.33448/rsd-v9i2.2150 ◽

2020 ◽

Vol 9 (2) ◽

pp. e128922150

Author(s):

Carla Giselly de Souza ◽

Severino Gonzaga Neto ◽

Lara Toledo Henriques ◽

Gherman Garcia Leal Araújo ◽

Luciana Thie Seki Dias ◽

...

Keyword(s):

Milk Production ◽

Tannic Acid ◽

Condensed Tannin ◽

Blood Parameters ◽

Corn Silage ◽

Neutral Detergent Fiber ◽

The Other ◽

Total Carbohydrate ◽

Lactating Cows ◽

Significant Difference

The present research objective was to evaluate the performance and blood parameters of lactating cows fed with a diet of two tannin sources, based on sorghum (condensed tannin) with increasing concentrations of tannic acid (hydrolyzable tannin’s). Increasing levels of tannic acid in a sorghum-based diet for five Holstein/Zebu crossbred lactating cows were subject to a 5 × 5 Latin square experimental design. To assess the effect on cow intake, digestibility, milk production, and blood parameters. All cows received 9.87 kg/DM of corn silage as roughage and 6.38 kg of concentrate consisting of 2.58 kg/DM of ground sorghum 0.87 kg/DM of cornmeal 1.32 kg/DM of soybean bran 0.44 kg/DM of wheat bran 0.2 kg/ DM of urea and 0.18 kg/ DM of mineral mixture. Diet 1 (control) contained low-tannin sorghum and the other diets contained high-tannin sorghum. The levels of tannic acid added to the diets were established based on the quantity of condensed tannin in high-tannin sorghum. Thus, diets 2, 3, 4 and 5 were supplemented with 1.5g (13.%DM), 79.5g (2.6%DM), 157.5g (3.9%DM) and 235.5g (5.2%DM) of tannic acid, totalling 0.078, 0.156, 0.234 and 0.321 total tannin kg/day respectively, to assess the effect on microbial protein synthesis. The diets contained 35 kg of corn silage (roughage) and 6.40 kg of concentrate. The natural and dry matter intake did not significantly differ between groups, except for ether extract (EE) intake that significantly differed. The DM apparent digestibility, crude protein, EE, neutral detergent fiber, total carbohydrate, and non-fibrous carbohydrate did not differ (P > 0.05) with the increase in dietary tannin supplementation. The GOT levels increased linearly. The blood glucose, triglyceride, and cholesterol (total, LDL and HDL) levels did not significantly differ. Hemoglobin showed a significant difference. No significant difference in urea, creatinine and uric acid occurred. Diets using two tannins sources supplementation caused no decrease in the dietary intake or digestibility in the animals. The GOT level changed significantly, showing linear behavior, however below the toxicity level, without any change in the other blood parameters. Milk production decreased with the increase in dietary tannin supplementation.

Download Full-text