Does hysteroscopy promote tumor cell proliferation in endometrial cancer?

2021 ◽  
Vol 50 (3) ◽  
pp. 28-30
Author(s):  
A. F. Urmancheeva ◽  
D. R. Zel'dovich ◽  
M. S. Shushania ◽  
A. V. Safronov
Keyword(s):  
Cell Proliferation ◽  
Endometrial Cancer ◽  
Comparative Analysis ◽  
Tumor Cell ◽  
Tumor Cell Proliferation ◽  
Tumor Cell Dissemination ◽  
Cytological Investigation ◽  
Promote Tumor Cell ◽  
Cell Dissemination

Peritoneal cytological investigation was carried out inpatients with endometrial cancer, who were subjected to hysteroscopy before the operation (37patients) or were operated on without hysteroscopy. Comparative analysis of the data didnt reveal the role of hysteroscopy in tumor cell dissemination.

Abstract 3044: The role of GPR110 in tumorigenicity, tumor cell dissemination, and cell cycle regulation in HER2+ breast cancer

2019 ◽  
Author(s):  
Raksha Bhat ◽  
Lanfang Qin ◽  
Carmine De Angelis ◽  
Suhas Vasaikar ◽  
Hariprasad Thangavel ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Tumor Cell ◽  
Cell Cycle Regulation ◽  
Tumor Cell Dissemination ◽  
Her2 Breast Cancer ◽  
Cell Dissemination ◽  
Cycle Regulation

Role of Thiamin (Vitamin B-1) and Transketolase in Tumor Cell Proliferation

2000 ◽  
Vol 36 (2) ◽  
pp. 150-154 ◽  
Author(s):  
Marta Cascante ◽  
Josep J. Centelles ◽  
Richard L. Veech ◽  
Wai-Nang Paul Lee ◽  
Laszlo G. Boros
Keyword(s):  
Cell Proliferation ◽  
Tumor Cell ◽  
Vitamin B ◽  
Tumor Cell Proliferation

Expression and prognostic role of SGTA in human breast carcinoma correlates with tumor cell proliferation

2014 ◽  
Vol 45 (6) ◽  
pp. 665-677 ◽  
Author(s):  
Ting Zhu ◽  
Zhengxiang Ji ◽  
Caixia Xu ◽  
Zhiyang Peng ◽  
Liang Gu ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Breast Carcinoma ◽  
Tumor Cell ◽  
Human Breast Carcinoma ◽  
Tumor Cell Proliferation ◽  
Human Breast ◽  
Prognostic Role

scholarly journals Role of 99mTc-(V)DMSA in Detecting Tumor Cell Proliferation

2007 ◽  
Vol 2 ◽  
pp. 117739010700200 ◽  
Author(s):  
Fatma Al-Saeedi
Keyword(s):  
Cell Proliferation ◽  
Tumor Cell ◽  
Tumor Cells ◽  
Dimercaptosuccinic Acid ◽  
Cell Detection ◽  
Tumor Cell Proliferation ◽  
Technetium 99M ◽  
Tumor Cell Detection ◽  
Technetium 99M Dimercaptosuccinic Acid

Pentavalent technetium-99m dimercaptosuccinic acid (99mTc-(V)DMSA) is a tumor-seeking agent which was introduced to evaluate, image, and manage many types of cancers. In this review, the beginning of, and the most recent applications of using this agent was appraised. The relation with tumor cell detection and proliferation was reported and several mechanisms of uptake of 99mTc-(V)DMSA in tumor cells are described.

scholarly journals Cancer-Preventive Role of Bone Marrow-Derived Mesenchymal Stem Cells on Colitis-Associated Colorectal Cancer: Roles of Gut Microbiota Involved

2021 ◽  
Vol 9 ◽  
Author(s):  
Ruohang He ◽  
Chaoqun Han ◽  
Ying Li ◽  
Wei Qian ◽  
Xiaohua Hou
Keyword(s):  
Colorectal Cancer ◽  
Stem Cells ◽  
Bone Marrow ◽  
Cell Proliferation ◽  
Mesenchymal Stem Cells ◽  
Tumor Cell ◽  
Rna Sequencing ◽  
Ribosomal Rna ◽  
Tumor Cell Proliferation

BackgroundMesenchymal stem cells (MSCs) treatment showed promising results in inflammatory bowel disease in both rodent models and patients. Nevertheless, previous studies conducted conflicting results on preclinical tumor models treated with MSCs concerning their influence on tumor initiation and progression. This study is designed to demonstrate the role of bone marrow-derived MSCs and the potential mechanism in the colitis-associated colon cancer (CAC) model.MethodsBone marrow-derived MSCs were isolated from green fluorescent protein-transgenic mice, cultured, and identified by flow cytometry. Azoxymethane and dextran sulfate sodium were administrated to establish the CAC mouse model, and MSCs were infused intraperitoneally once per week. The mice were weighed weekly, and colon length, tumor number, and average tumor size were assessed after the mice were killed. MSC localization was detected by immunofluorescence staining; tumor cell proliferation and apoptosis were measured by immunohistochemistry staining of Ki-67 and terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick end labeling assay, respectively. The colonic tumor tissues were isolated for RNA-seq, and fecal samples were collected for 16S ribosomal RNA sequencing of the microbiome.ResultsAfter injection intraperitoneally, MSCs migrated to the intestine and inhibited the initiation of colitis-associated colorectal cancer. This inhibition effect was marked by less weight loss, longer colon length, and reduced tumor numbers. Moreover, MSCs reduced tumor cell proliferation and induced tumor cell apoptosis. Furthermore, MSCs could inhibit chronic inflammation assessed by RNA-sequencing and promote gut microbiome normalization detected by 16S ribosomal RNA sequencing.ConclusionThe results proved that MSCs could migrate to the colon, inhibit chronic inflammation, and regulate gut microbiome dysbiosis to suppress the development of CAC.

scholarly journals HNSCC subverts PBMCs to secrete soluble products that promote tumor cell proliferation

Oncotarget ◽  
2017 ◽  
Vol 8 (37) ◽  
pp. 60860-60874 ◽  
Author(s):  
Marcell Costa de Medeiros ◽  
Rajat Banerjee ◽  
Min Liu ◽  
Giovana Anovazzi ◽  
Nisha J. D’Silva ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Tumor Cell ◽  
Tumor Cell Proliferation ◽  
Promote Tumor Cell
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