Reproductive function in patients with uterine myoma

1985 ◽  
Vol 66 (2) ◽  
pp. 105-107
Author(s):  
I. M. Mazitov ◽  
T. I. Timofeeva ◽  
N. I. Raimova ◽  
I. M. Bogolyubova
Keyword(s):  
Sexual Function ◽  
Uterine Fibroids ◽  
Reproductive Function ◽  
Uterine Myoma

The concept of the role of sexual function in the development of uterine fibroids is still controversial.

scholarly journals Uterine fibroids and effiency of in vitro fertilization programs

2016 ◽  
Vol 65 (6) ◽  
pp. 79-87 ◽  
Author(s):  
Lyailya Kh Dzhemlikhanova ◽  
Dariko A Niauri ◽  
Zarina K Abdulkadyrova
Keyword(s):  
In Vitro Fertilization ◽  
Uterine Fibroids ◽  
Endometrial Receptivity ◽  
Female Infertility ◽  
Uterine Myoma ◽  
Vitro Fertilization ◽  
Etiologic Role

The aim of this review is to estimate etiologic role of uterine fibroids in female infertility; it based on the results of current studies of infertility in various cases of fibroids (submucous, intramural and subserous). In article was analyzed the efficiency of the treatment of infertility in women with uterine myoma in IVF programs.Conclusion: a detailed study of endometrial receptivity in women with uterine fibroids is necessary to for personalized strategy in patients with uterine fibroids (myoma) and infertility.

scholarly journals Current trends in the pharmacotherapy of uterine myoma, associated with heavy menstrual bleeding and anemia: review

2020 ◽  
Author(s):  
Z. V. Revazova ◽  
L. V. Adamyan ◽  
O. N. Loginova ◽  
L. M. Manukyan ◽  
K. N. Arslanyan
Keyword(s):  
Uterine Fibroids ◽  
Reproductive Function ◽  
Uterine Myoma ◽  
Reproductive Age ◽  
Heavy Menstrual Bleeding ◽  
Menstrual Bleeding ◽  
Cochrane Library ◽  
Pharmacological Agents ◽  
Surgical Interventions ◽  
Current Trends

Aim: to summarize results of up-to-date world researches on the current trends of symptomatic myoma treatment.Materials and Мethods. A search of publications was carried out in the main international databases in Russian and English languages: PubMed/MEDLINE, The Cochrane Library, Embase, eLibrary. The analysis included studies published over the past 10 years examining the clinical efficacy and safety of various groups of pharmacological agents for the treatment of uterine myoma combined with heavy menstrual bleeding in women of reproductive age.Results. Currently, the treatment of uterine fibroids is divided into three main methods: surgical, minimally invasive organ-preserving methods, and pharmacotherapy. Until now, surgical intervention remains the main method of treatment, and, unfortunately, is often carried out in the volume of hysterectomy. However, today it is important to have a personalized approach to the management of a patient with symptomatic uterine myoma, taking into account her desire to preserve reproductive function. The development of the possibilities of drug therapy made a great contribution to the optimization of managing such patients.Conclusion. The global trend is to decrease the number of radical interventions, as well as the development and improvement of new methods of treating symptomatic uterine fibroids. Currently, pharmacotherapy of leiomyoma can significantly improve the quality of life of patients, reduce radical surgical interventions, optimize surgical treatment, and in certain situations, completely eliminate the need for surgery.

The structure of somatic dysfunctions in women with a nodular form of uterine myoma

2020 ◽  
pp. 29-40
Author(s):  
G. N. Chebotaeva ◽  
D. S. Lebedev
Keyword(s):  
Local Level ◽  
Randomized Study ◽  
Random Number Generator ◽  
Uterine Fibroids ◽  
Reproductive Function ◽  
Uterine Myoma ◽  
Dynamic Monitoring ◽  
Control Group ◽  
Gynecological Examination ◽  
The Impact

Introduction. Uterine myoma (leiomyoma) occupies one of the first placesin the structure of gynecological diseases.This disease negatively affects both the state of health and the reproductive function of women. Now the problem of the effective methods for the treatment of leiomyoma (including non-medicinal methods, one of which is the osteopathic correction of somatic dysfunctions) is still acutedespite some progress in understanding the mechanisms of this disease pathogenesis. However, the structure of these functional disorders has not been practically studied.The goal of research — to investigate the structure of somatic dysfunctions (SD) in women with uterine myoma before and after osteopathic correction and its relationship with the severity of subjective indicators.Materials and methods. A simple longitudinal randomized study was conducted in 2018–2019 on the basis of a women’s consultation in Kirov, it included 30 women aged 35 to 44 years being under the medical supervision of an obstetrician-gynecologist, with a diagnosis of intramural uterine myoma, nodular form. All women with intramural nodular leiomyoma were divided into 2 groups of 15 people, comparable in age, presence of comorbidities and duration of the disease, using a simple randomization method (a random number generator was used). The main group received osteopathic treatment, and for patients of the control group it was carried out dynamic monitoring. According to the scheme, all patients underwent a clinical gynecological examination, a clinical osteopathic examination, and the dynamics of the severity of subjective manifestations (complaints) was evaluated.The collected data was processed by nonparametric statistics.Results. In the course of osteopathic diagnostics in women with uterine fibroids the following SD were identified: the somatic dysfunctions of the pelvic region dominated among the regional SD, and the most common among the local SD were the somatic dysfunctions of the segment С0–СI and the thoracic diaphragm. As the result of osteopathic correction of diagnosed SD in patients with leiomyoma, the decrease of the total number of SD (p<0,05) and the change of their structure has occurred (before treatment the SD at the regional level prevailed, after treatment there was a reduction in their number, and the increasing of the number of SD local level due to the carried out correction of most existing regional violations); and the severity of subjective symptom (algodismenorrhea) has decreased (p<0,05).Conclusion. In women with uterine myoma (leiomyoma), SD can manifest at different levels. Osteopathic correction of SD in women with uterine myomasignificantly reduces the severity of subjective manifestations (algodismenorrhea), which allows us to continue the research in studying of the impact of the SD osteopathic correction in the complex treatment of women with intramural nodular form of uterine myoma. 

scholarly journals Reproductive outcomes following surgical removal of uterine fibroids

2019 ◽  
pp. 110-118
Author(s):  
A. E. Mitichkin ◽  
Yu. E. Dobrokhotova ◽  
N. Yu. Ivannikov ◽  
V. I. Dimitrova ◽  
O. A. Slyusareva ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Drug Withdrawal ◽  
Uterine Fibroids ◽  
Reproductive Function ◽  
Uterine Myoma ◽  
Surgical Removal ◽  
Birth Canal ◽  
Uterine Arteries ◽  
Natural Birth ◽  
Prospective Comparative Study

The cohort prospective comparative study investigated the efficacy of mifepristone use in patients after surgical treatment of uterine myoma. It was shown that the use of mifepristone at a dose of 50 mg/day in a continuous mode for 3 months after surgical treatment for proliferating uterine myoma led to the absence of recurrences of the disease for 2 years after the drug withdrawal. The use of mifepristone after embolization of uterine arteries allowed to significantly reduce the size of the node by 25% during 12 months and by 50% (p<0.05) after 24 months. Complex treatment of uterine myoma, including myomectomy and drug therapy with mifepristone, allowed to realize reproductive function in 46% of patients, and delivery through the natural birth canal occurred in 24% of patients.

scholarly journals ROLE OF MYOMECTOMY IN INFERTILITY TREATMENT

2013 ◽  
Vol 62 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Andrey Kirillovich Dolinskiy
Keyword(s):  
Uterine Fibroids ◽  
Infertility Treatment ◽  
Uterine Myoma ◽  
Surgical Strategy ◽  
The Subject

The Up to now, the role of uterine fibroids in the genesis of infertility and IVF failures is the subject of debate.Analysis of literature demonstrated that surgical strategy in patients with uterine myoma and infertility should be individualized. Along with the classic indications for myomectomy in women with infertility there are additional indications:

scholarly journals Effect of transforming growth factor-β2 on uterine leiomyoma cells proliferation

2015 ◽  
Vol 96 (6) ◽  
pp. 968-970
Author(s):  
N D Muratova ◽  
A A Abduvaliev
Keyword(s):  
Growth Factor ◽  
Cytotoxic Activity ◽  
Uterine Leiomyoma ◽  
Transforming Growth Factor ◽  
Uterine Fibroids ◽  
Uterine Myoma ◽  
Reproductive Age ◽  
Culture Cells ◽  
Transforming Growth Factor Β2

Aim. To study the role of transforming growth factor-β2 in the uterine leiomyoma pathogenesis. Methods. Studies to determine the cytotoxic activity of the transforming growth factor-β2 regarding the temporary cell culture were conducted. The operational material was used from two women of reproductive age with uterine myoma (multiple symptomatic uterine myoma, proliferative type) who underwent hysterectomy. Patients mean age was 43.5±0.57. Obtained temporary culture cells were split into five groups depending on the transforming growth factor-β2 affecting dose (1000, 500, 100, 10 µg/10×106, and culture with no exposure). After incubation living and dead cells were counted at 280 times magnification. The cytotoxic activity was expressed as a percentage of live and dead cells. Results. Total cell death (necrosis) was 23.0% when using factor at the dose 10 µg/10×106 cells, at the dose 100 µg/ 10×106 cells - 34.5%, at the dose 500 µg/10×106 cells - 44%, at the dose 1000 µg/10×106 cells - 59.5%. The most effective vital life suppressing activity of the transformed cells was observed when exposed to transforming growth factor-β2 at the dose 1000 µg/10×106 cells. Conclusion. Transforming growth factor-β2 is capable to suppress the proliferating uterine fibroids growth under certain conditions and the dose, it has a significant dose-dependent cytotoxic effect in respect of the neoplasm.

Role of chromium (III) in the nutrition of pigs and cattle

2016 ◽  
Vol 3 (2) ◽  
pp. 56-62
Author(s):  
R. Iskra ◽  
V. Vlizlo ◽  
R. Fedoruk
Keyword(s):  
Growth And Development ◽  
Reproductive Function ◽  
Metabolic Effect ◽  
Considerable Part ◽  
Cultural Medium ◽  
Milk Performance ◽  
Chromium Compounds ◽  
The Impact ◽  
Different Sources

The results of our studies and the data of modern literature regarding the biological role of Cr(III) compounds in conditions of their application in the nutrition for pigs and cattle are discussed. The metabolic impact of Cr(III), coming from different sources – mineral and organic compounds, obtained by chemical synthesis or a nanotechnological method (chromium citrate), as well as in the form of biocomplexes from the cultural medium of Saccharomyces cerevisiae yeasts was analyzed. The metabolic connection between the impact of Cr(III) and the biosynthesis of some hormones – insulin, cortisol – as well as the sensitivity of some tissues and organs to the effect of chromium compounds was studied. A considerable part of the review material was dedicated to the metabolic effect of Cr(III) compounds on the reproductive function of pigs and cattle and their impact on the viability of the offspring and gametes of animals. The data about the stimulating effect of Cr(III) on the growth and development of the organism of piglets and calves, meat and milk performance of these species of animals are discussed. The relevance of dosing Cr(III) in the nutrition of pigs and cattle is highlighted.

Modern approaches to the prevention and treatment of alterations in reproductive health in women with somatoform disorders and autonomic homeostasis

2016 ◽  
pp. 98-101
Author(s):  
Vl.V. Podolsky ◽  
◽  
V.V. Podolsky ◽  
Keyword(s):  
Reproductive Health ◽  
Hormonal Regulation ◽  
Preventive Measures ◽  
Somatoform Disorders ◽  
Emotional Health ◽  
Uterine Fibroids ◽  
Reproductive Function ◽  
Epidemiological Studies ◽  
Prevention And Treatment ◽  
Artificial Abortion

The objective: the developing of a system of preventive measures and principles of pregravid preparation for women with somatoform disorders and violation of autonomic homeostasis (VAH), in which observed changes in reproductive health (CRH) in the shape of states after undergoing artificial abortion, infertility and uterine fibroids. Patients and methods. Conducted clinical and epidemiological studies in the population of women of fertile age (WFA) allowed identifying for further examination of women with CRH in the form of state after undergoing artificial abortion, infertility and uterine fibroids in women with VAH. Further women were examined, in particular the conducted clinical and instrumental methods of research; determined the state of autonomic homeostasis and psycho emotional health of the biotopes of the organism, immunity; analyzed the hormonal regulation of the menstrual cycle; performed genetic studies and determined the morphofunctional state of reproductive system. Results. The most frequent complications during pregnancy in women who had CRH in history in the form of abortions, infertility and uterine fibroids and in the background of the PAF, there was a threat of interruption of pregnancy (often in I and II trimester – 56%) and preterm delivery (21%). The study of the catamnesis of further reproductive health found that in the case of well-conducted therapeutic measures in women undergoing artificial abortion, had infertility and uterine leiomyoma in the background of VAH, restore reproductive function, and in 82% of cases occurred a pregnancy. Conclusion. The the provided study of reproductive health, and state of various organs and systems of fertile aged women with somatoform disorders and violations of the autonomic homeostasis allowed to develop preventive measures for these women and pregravid preparation with the inclusion to the therapy Magnesium and vitamins (Magne-В6®). Key words: somatoform disorders, violation of autonomic homeostasis, changes in reproductive health, prevention and treatment, women of fertile age, Magne-В6®.

The Effects of Herbal Medicines on Women Sexual Dysfunction: A Systematic Review

2020 ◽  
Vol 17 ◽  
Author(s):  
Tahereh Molkara ◽  
Maliheh Motavasselian ◽  
Farideh Akhlaghi ◽  
Mohammad Arash Ramezani ◽  
Hamideh Naghedi Baghdar ◽  
...  
Keyword(s):  
Sexual Dysfunction ◽  
Herbal Medicine ◽  
Sexual Health ◽  
Sexual Function ◽  
Psychological Health ◽  
Health Management ◽  
Herbal Medicines ◽  
Physical And Psychological Health ◽  
Female Sexual Response

: Sexual health plays an important role in the women’s health and quality of life. Sexual health management is a prerequisite for physical and psychological health of women. Sexual desire, arousal, and orgasm are three factors of female sexual response. So far many different methods has been known for the treatment of female sexual dysfunction, however none of them are not an efficacious therapy. Generally, use of herbal medicine is a safe and effective therapeutic method in the treatment of women with sexual dysfunction. The role of herbal and nutritional supplementation in female sexual function has attracted researchers’ interest in recent years. This study aimed to the evaluation of the studies focusing on the herbal medicine on women sexual function and the assessment of its effectiveness.

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