Differential diagnosis in acute appendicitis

1927 ◽  
Vol 23 (1) ◽  
pp. 66-73
Author(s):  
N. N. Nazarov
Keyword(s):  
Differential Diagnosis ◽  
Acute Appendicitis ◽  
Clinical Picture ◽  
Inflammatory Process ◽  
Good Reason ◽  
The Other ◽  
Internal Genitalia ◽  
The One

Pathological processes in the gallbladder, duodenum and stomach on the one hand, and in the internal genitalia of women on the other, indeed often create a clinical picture of a disease full of uncertainties. In looking for a solid basis for practical measures, sometimes obviously urgent, in such cases, not without good reason, the surgeon fixes his attention, among others, on a possible disease of the appendix of the appendix. In other cases, the inflammatory process in the appendix itself, accompanied by symptoms not quite peculiar to this disease, does not allow to exclude the possibility of disease also in the mentioned areas above and below the appendix.

scholarly journals Вміст фактора некрозу пухлин α і трансформуючого фактора росту β1 у сироватці крові хворих на гострий апендицит та абдомінальний туберкульоз

2018 ◽  
Author(s):  
V. M. Akimova
Keyword(s):  
Differential Diagnosis ◽  
Immune System ◽  
Serum Level ◽  
Acute Appendicitis ◽  
Inflammatory Process ◽  
Abdominal Cavity ◽  
Abdominal Tuberculosis ◽  
Urgent Problem ◽  
Elisa Method ◽  
Chronic Inflammatory Process

Introduction. Differential diagnosis of acute appendicitis with abdominal tuberculosis is аn urgent problem of medicine. Тhe immune system is involved іn the pathogenesis of diseases, and cytokines are the regulators of inflammation.The aim of the study – to determine the level of cytokines with the pro- and anti-inflammatory potential of TNFα and TGFβ1 and their correlation in the blood of patients with acute appendicitis and abdominal tuberculosis in order to improve diagnosis and treatment tactics. Research Methods. 51 patients with urgent abdominal pathology were examined, 21 of them with phlegmonous form of acute appendicitis, 30 patients with histologically confirmed diagnosis of abdominal tuberculosis. The content of TNFα и ТGFβ1 in serum was examined by the ELISA method by the reagents “Diaclone” and “DRG Diagnostic”.Results and Discussion. The results of studies have shown that the development of acute and chronic inflammatory process in the abdominal cavity is determined by activation of the macrophage-monocytic system, manifested by a significant increase in the serum level of TNFα. It was established that in patients with abdominal tuberculosis on the background of increased serum level of TNFα ((17.57±1.05) vs. (4.97±0.18) pg/ml) the TGFβ1 level does not differ from the control ((16.52±1.15) vs. (17.94±0.71) ng/ml) at that time, as with acute appendicitis, its level decreased ((11.32±0.65) vs. (17.94±0.71) ng/ml). ТGFβ1/TNFα ratio during the abdominal inflammation was much lower than control, but in abdominal tuberculosis in 1.5 times higher than in acute appendicitis.Conclusions. The serum level and ratio of monocyte-macrofage derived TNFα and ТGFβ1 determines the type of inflammation and may be useful in differential diagnostic of acute appendicitis and abdominal tuberculosis.

scholarly journals Lipid-Induced Mechanisms of Metabolic Syndrome

2020 ◽  
Vol 2020 ◽  
pp. 1-14
Author(s):  
Yulia K. Denisenko ◽  
Oxana Yu Kytikova ◽  
Tatyana P. Novgorodtseva ◽  
Marina V. Antonyuk ◽  
Tatyana A. Gvozdenko ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Fatty Acids ◽  
Inflammatory Process ◽  
Molecular Mechanisms ◽  
Insulin Response ◽  
The Body ◽  
Diagnostic Methods ◽  
The Other ◽  
Prevention And Treatment ◽  
The One

Metabolic syndrome (MetS) has a worldwide tendency to increase and depends on many components, which explains the complexity of diagnosis, approaches to the prevention, and treatment of this pathology. Insulin resistance (IR) is the crucial cause of the MetS pathogenesis, which develops against the background of abdominal obesity. In light of recent evidence, it has been shown that lipids, especially fatty acids (FAs), are important signaling molecules that regulate the signaling pathways of insulin and inflammatory mediators. On the one hand, the lack of n-3 polyunsaturated fatty acids (PUFAs) in the body leads to impaired molecular mechanisms of glucose transport, the formation of unresolved inflammation. On the other hand, excessive formation of free fatty acids (FFAs) underlies the development of oxidative stress and mitochondrial dysfunction in MetS. Understanding the molecular mechanisms of the participation of FAs and their metabolites in the pathogenesis of MetS will contribute to the development of new diagnostic methods and targeted therapy for this disease. The purpose of this review is to highlight recent advances in the study of the effect of fatty acids as modulators of insulin response and inflammatory process in the pathogenesis and treatment for MetS.

Swyer-James Syndrome: A Cause of Hyperlucent Lung

1975 ◽  
Vol 84 (5) ◽  
pp. 657-661 ◽  
Author(s):  
Jacobo Guzowski ◽  
Arndt J. Duvall
Keyword(s):  
Differential Diagnosis ◽  
Foreign Body ◽  
Pulmonary Artery ◽  
Clinical Picture ◽  
Inflammatory Process ◽  
Bronchial Tree ◽  
Obliterative Bronchiolitis ◽  
Air Trapping ◽  
Presumptive Diagnosis ◽  
Hyperlucent Lung

Swyer-James syndrome consists of an abnormal radiolucency of one lung or lobe, secondary to obliterative bronchiolitis with distal air trapping. The etiology of the bronchiolar inflammatory process is quite diverse. The syndrome will simulate the presence of a foreign body in the bronchial tree, and the patients will usually undergo bronchoscopy with that presumptive diagnosis. Two cases are presented and the pathogenesis, clinical picture, and differential diagnosis are outlined. The separation of this condition from hypoplasia of the pulmonary artery is discussed.

scholarly journals Complex clinical presentations of depression and its best therapeutic responses

2020 ◽  
Vol 1 (1) ◽  
pp. 104
Author(s):  
Janus Kremer
Keyword(s):  
Differential Diagnosis ◽  
Bipolar Depression ◽  
Treatment Strategies ◽  
Deep Understanding ◽  
The Other ◽  
Psychotic Depression ◽  
Working Together ◽  
The Rich ◽  
The One ◽  
Definition Of

I have gratefully read this book. I had the pleasure and honor of sharing more than 30 years of working together with the authors. Each one of them, are leaders in their fields, and hallmarks of the Argentinean Psychiatry.This book is extremely well written. It covers aspects of everyday practice with simplicity to be easily understood by young doctors as well as provides high quality of updated concepts that were be of enormous utility to senior neuropsychiatric staff involved in the care of patients with depression and its resistant to treatment form of presentation.Andrea Lopez Mato excels in a didactyly approaching the neurobiological and neuroendocrine pathways leading to depression. Her approach is one way, easily understandable, but on the other hand, specially with the graphics and figures gives a deep understanding of such a complex aspect of mental illness.Pablo Miguel Bagnati’s chapter focusses on depression in neurological disorders. It is clear to me when I read this chapter, that the author has an enormous experience dealing with this populationin everyday of his clinical practice. His graphics are absolutely appropriate and very didactive.Marcelo Cetkovich Bakmas approaches with an exquisite precision an extremely complex such as Psychotic depression is. In this chapter is discussed the definition of the concept, its difficulties in the differential diagnosis, the widely aspects of how can it clinically present and the different potential treatments, As well, regarding the etiology of the psychotic depression, the author gets into neurobiological hypothesis, sharing with the reading public a complete scope of this challenging and frequent clinical presentation.Gustavo Vazquez gets into one of the one most challenging aspects of modern psychiatry: the bipolar depression. The field is faced with excellence, avoiding simplification and getting into the labyrinths of such an intricate chapter of neuropsychatric clinic. The author discusses the etiology, differential diagnosis, clinical classifications and potential treatment strategies. In conclusion, I found this book easy to read in one hand, and rich, complete and complex in the other. In my humbled opinion, this book will be of enormous aid to junior and senior staff involved in the rich world of modern neuropsychiatry.

Loyalty: The Missing Virtue

2018 ◽  
Author(s):  
David Konstan
Keyword(s):  
Good Reason ◽  
The Other ◽  
Georg Simmel ◽  
Ancient Greek ◽  
Delicate Balance ◽  
The One

Ancient Greek and Roman moralists seem not to have identified loyalty as a specific virtue, and for good reason: loyalties can be divided or misdirected. Affection or love (philia) was the ground of commitment. As the sociologist Georg Simmel observed, “If love continues to exist in a relationship between persons, why does it need faithfulness . . . ? Faithfulness might be called the inertia of the soul. It keeps the soul on the path on which it started, even after the original occasion that led it onto it no longer exists.” The contrast between the classical emphasis on love as the basis of constancy and the modern regard for loyalty is illustrated by way of analyses of Euripides’ tragedy Orestes and Menander’s comedy Epitrepontes (Arbitrants), on the one hand, and John Galsworthy’s drama Loyalties and Edward Albee’s A Delicate Balance, on the other.

Anachronism in Greek tragedy

1985 ◽  
Vol 105 ◽  
pp. 1-10 ◽  
Author(s):  
P. E. Easterling
Keyword(s):  
Greek Tragedy ◽  
Good Reason ◽  
The Other ◽  
The Past ◽  
The One

Anachronism-hunting has been out of fashion with scholars in recent times, for the good reason that it can easily seem like a rather trivial sort of parlour game. But given that Greek tragedy draws so heavily on the past, a close look at some examples may perhaps throw light on a far from trivial subject, the dramatists' perception of the heroic world.So long as anachronism was treated as an artistic failing the debate was bound to be unproductive; one can symphathise with Jebb's view (on Soph. El. 48 ff.) that Attic tragedy was ‘wholly indifferent’ to it. And one can see why later scholars have objected to the very idea of anachronism as irrelevant and misleading. Ehrenberg, for example, wrote in 1954: ‘It is entirely mistaken to distinguish between mythical and thus quasi-historical features on the one hand and contemporary and thus anachronistic on the other. There is always the unity of the one poem or play, displaying the ancient myth, although shaped in the spirit of the poet's mind and time.’

Leonhard's Classification of Schizophrenia

1958 ◽  
Vol 104 (437) ◽  
pp. 943-971 ◽  
Author(s):  
Frank Fish
Keyword(s):  
Clinical Picture ◽  
History Of Psychiatry ◽  
The Other ◽  
Present Communication ◽  
Other Hand ◽  
History Of ◽  
The One ◽  
Clinical Pictures ◽  
Preparatory Work

Jaspers (1946) has pointed out that in the history of psychiatry one can distinguish two main types of psychiatrist. On the one hand there is the describer who depicts a lively clear clinical picture and communicates it to the reader in everyday speech. On the other hand there is the analyst who dissects the clinical picture and tries to obtain clear concepts about the abnormal phenomena. The describer is always popular because little effort is required to understand his views and appreciate his clinical descriptions. However it is much more difficult to understand the analyst as this requires time-consuming preparatory work and an attempt to apply the analyst's views in practice. Thus anyone who wishes to understand the views of Kleist and Leonhard, who are the modern representatives of the great clinical analyst Carl Wernicke, has a difficult task. If therefore this present communication appears to disagree with other work recently published by the author (Fish, 1957b, 1958) then all that can be said in extenuation is that the analysis of clinical pictures is difficult and one can only achieve accuracy in this field by learning from mistakes.

scholarly journals Rare presentations of acute appendicitis

2019 ◽  
Vol 7 (1) ◽  
pp. 317
Author(s):  
Pon Rachel Vedamanickam
Keyword(s):  
Differential Diagnosis ◽  
Acute Appendicitis ◽  
Acute Abdomen ◽  
Iliac Fossa ◽  
Atypical Symptoms ◽  
Right Iliac Fossa Pain ◽  
The One ◽  
The Mind ◽  
Symptoms And Signs

Acute appendicitis is the one of the most common emergency conditions that the rural surgeon must deal with. Though the majority of patients present with the typical symptoms of right iliac fossa pain, nausea and anorexia, many patients do present with atypical symptoms and signs. These patients present a challenge to rural surgeons. Acute appendicitis is a great mimic and can present with a variety of symptoms. The eyes don’t see what the mind doesn’t know and it is important to know the various ways in which appendicitis can present and to always keep it as a differential diagnosis while managing a patient with acute abdomen. In this paper we have looked at 4 different presentations of appendicitis. Appendicitis is a great mimic and should always be kept as a differential for acute abdomen.

scholarly journals The case of erythrophobia

2020 ◽  
Vol V (4) ◽  
pp. 153-160
Author(s):  
N. M. Popov
Keyword(s):  
Clinical Picture ◽  
The Other ◽  
General Terms ◽  
Other Hand ◽  
Prominent Symptom ◽  
The Face ◽  
To Come ◽  
The One

In the specialized literature for the last time, a description of a rather peculiar nervous suffering began to come across, which Pitres and Rgis called erythrophobia and the most prominent symptom of which is the periodically arising fear of reddening, on the one hand, a fearful reddening of the face, on the other hand. Apparently, the first indication of such a combination of clinical phenomena we find in Casper back in 1846. But the observation of this author, known to me only from the work of Westphalya (Ueber Zwangsvorstellungen. 1877. Berl. Klin. Woch. 1877), is too cited last day in general terms, so that one can speak about him with the desired certainty. After Casper, not one of the clinicians focused their attention on such cases, and only in 1896 appeared almost simultaneously several works devoted to the suffering of interest to us. Dugas (Revue philosophique, dec. 1896), Campbell (Brif. Med. Journal, 25 sept. 1896); Breton (Gazette des hpit. 20 oct. 1896), Pitres et Rgis (Archives de Neurologie 1896 No. 9. p. 253), Bekhterev (Review of Psychiatry 1896, No. 12; 1897 No. 1 and 8), Chigaev (Doctor 1897 30), Manheimer (La mdecine modern 1897 No. 8) published a whole series of observations in which the clinical picture of suffering is described in great detail and where its main features are already quite definite.

Accidental Poisoning with Deadly Nightshade Berries: a Case Report

1984 ◽  
Vol 3 (6) ◽  
pp. 513-516 ◽  
Author(s):  
G. Trabattoni ◽  
D. Visintini ◽  
G.M. Terzano ◽  
A. Lechi
Keyword(s):  
Case Report ◽  
Clinical Picture ◽  
Delirium Tremens ◽  
The Other ◽  
Accidental Poisoning ◽  
Atropa Belladonna ◽  
Healthy Man ◽  
Subacute Dementia ◽  
The One ◽  
Experimentally Induced

1 A case of acute accidental poisoning with deadly nightshade (Atropa belladonna) berries is reported. The patient was an elderly but healthy man who soon recovered. 2 On the one hand, the clinical picture looked similar to that of delirium tremens; on the other, there were myoclonic jerks and signs of extrapyramidal involvement to suggest the onset of subacute dementia. 3 The electroencephalogram findings confirmed those already reported during experimentally induced intoxication after ingestion of atropine in man.

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