scholarly journals Вміст фактора некрозу пухлин α і трансформуючого фактора росту β1 у сироватці крові хворих на гострий апендицит та абдомінальний туберкульоз

2018 ◽  
Author(s):  
V. M. Akimova
Keyword(s):  
Differential Diagnosis ◽  
Immune System ◽  
Serum Level ◽  
Acute Appendicitis ◽  
Inflammatory Process ◽  
Abdominal Cavity ◽  
Abdominal Tuberculosis ◽  
Urgent Problem ◽  
Elisa Method ◽  
Chronic Inflammatory Process

Introduction. Differential diagnosis of acute appendicitis with abdominal tuberculosis is аn urgent problem of medicine. Тhe immune system is involved іn the pathogenesis of diseases, and cytokines are the regulators of inflammation.The aim of the study – to determine the level of cytokines with the pro- and anti-inflammatory potential of TNFα and TGFβ1 and their correlation in the blood of patients with acute appendicitis and abdominal tuberculosis in order to improve diagnosis and treatment tactics. Research Methods. 51 patients with urgent abdominal pathology were examined, 21 of them with phlegmonous form of acute appendicitis, 30 patients with histologically confirmed diagnosis of abdominal tuberculosis. The content of TNFα и ТGFβ1 in serum was examined by the ELISA method by the reagents “Diaclone” and “DRG Diagnostic”.Results and Discussion. The results of studies have shown that the development of acute and chronic inflammatory process in the abdominal cavity is determined by activation of the macrophage-monocytic system, manifested by a significant increase in the serum level of TNFα. It was established that in patients with abdominal tuberculosis on the background of increased serum level of TNFα ((17.57±1.05) vs. (4.97±0.18) pg/ml) the TGFβ1 level does not differ from the control ((16.52±1.15) vs. (17.94±0.71) ng/ml) at that time, as with acute appendicitis, its level decreased ((11.32±0.65) vs. (17.94±0.71) ng/ml). ТGFβ1/TNFα ratio during the abdominal inflammation was much lower than control, but in abdominal tuberculosis in 1.5 times higher than in acute appendicitis.Conclusions. The serum level and ratio of monocyte-macrofage derived TNFα and ТGFβ1 determines the type of inflammation and may be useful in differential diagnostic of acute appendicitis and abdominal tuberculosis.

Differential diagnosis in acute appendicitis

1927 ◽  
Vol 23 (1) ◽  
pp. 66-73
Author(s):  
N. N. Nazarov
Keyword(s):  
Differential Diagnosis ◽  
Acute Appendicitis ◽  
Clinical Picture ◽  
Inflammatory Process ◽  
Good Reason ◽  
The Other ◽  
Internal Genitalia ◽  
The One

Pathological processes in the gallbladder, duodenum and stomach on the one hand, and in the internal genitalia of women on the other, indeed often create a clinical picture of a disease full of uncertainties. In looking for a solid basis for practical measures, sometimes obviously urgent, in such cases, not without good reason, the surgeon fixes his attention, among others, on a possible disease of the appendix of the appendix. In other cases, the inflammatory process in the appendix itself, accompanied by symptoms not quite peculiar to this disease, does not allow to exclude the possibility of disease also in the mentioned areas above and below the appendix.

scholarly journals Interleukin-6 as Immune System and Inflammation Biomarker on the Response of Basic Pencak Silat Exercise in Perguruan Pencak Silat Perisai Diri, Bojonegoro

2021 ◽  
Vol 9 (T6) ◽  
pp. 179-183
Author(s):  
Roy Irawan ◽  
Trias Mahmudiono ◽  
Tri Martiana
Keyword(s):  
Immune System ◽  
Serum Level ◽  
Training Program ◽  
Interleukin 6 ◽  
High Intensity ◽  
Elisa Method ◽  
Acute Response ◽  
Self Defense ◽  
Significant Difference ◽  
New Students

BACKGROUND: Pencak Silat is a self-defense exercise originated from Indonesia and categorized as a high-intensity exercise. AIM: This research was intended to identify the acute response of Pencak Silat basic exercise toward interleukin-6 (IL-6) as an immune system biomarker on students of Perguruan Pencak Silat Perisai Diri Tulungrejo, Bojonegoro. METHODS: A number of 26 students (10 boys and 16 girls) of Perguruan Pencak Silat Tulungrejo, Bojonegoro, were participated in this study. The students did the 2 h Perguruan Pencak Silat Perisai Diri, Bojonegoro, training program with 75–85% intensity. The IL-6 serum was measured using ELISA method. RESULTS: The result of this study showed that the IL-6 serum level in post-2 (12 h after training) (6.2981 pg/mL) was higher compared with the IL-6 serum level in post-1 (shortly after training) (6.11981 pg/mL) and before training (4.5146 pg/mL). The result also showed that there was a significant difference of IL-6 levels between pre-training and after training. CONCLUSION: This study concluded that the basic exercise performed by the new students of Perguruan Pencak Silat Perisai Diri increased IL-6 serum level.

A Serological Storm

1970 ◽  
Vol 9 (2) ◽  
Author(s):  
Bertha Wong MD ◽  
Maria Bagovich MD ◽  
Ivan Blasutig PhD ◽  
Simon Carette MD MPhil
Keyword(s):  
Differential Diagnosis ◽  
Hepatitis C Virus ◽  
Immune System ◽  
Hepatitis C ◽  
Hcv Infection ◽  
Clinical Context ◽  
Autoantibody Profile ◽  
Life Threatening ◽  
Clinically Significant ◽  
Sensory Polyneuropathy

This article describes a patient presenting with a sensory polyneuropathy and multiple autoantibodies, leading to the diagnosis of hepatitis C virus (HCV) infection. His widely positive autoantibody profile in the absence of clinically significant rheumatic disease illustrates the importance of interpreting autoimmune serology in the appropriate clinical context and the concept of HCV being a non-specific activator of the immune system. In addition, it highlights the importance of considering untreated HCV infection in the differential diagnosis of rheumatic complaints, particularly if the workup reveals multiple autoantibodies, as HCV is a potentially severe and life-threatening disease, which can be appropriately managed with effective antiviral therapy.

The significance of urinary beta-2 microglobulin level for differential diagnosis of familial Mediterranean fever and acute appendicitis

2016 ◽  
Vol 35 (7) ◽  
pp. 1669-1672 ◽  
Author(s):  
Yunus Ugan ◽  
Hakan Korkmaz ◽  
Atalay Dogru ◽  
Yavuz Savas Koca ◽  
Ayse Balkarlı ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Familial Mediterranean Fever ◽  
Acute Appendicitis ◽  
Mediterranean Fever ◽  
Beta 2 ◽  
Beta 2 Microglobulin

Toxoplasma Appendicitis: A Once-in-a-Lifetime Diagnosis!

2017 ◽  
Vol 26 (1) ◽  
pp. 89-92 ◽  
Author(s):  
Anisha M. Fernandes ◽  
Maheshkumar M. Lakhe ◽  
Sanjay A. Pai
Keyword(s):  
Differential Diagnosis ◽  
Acute Appendicitis ◽  
Muscularis Propria ◽  
Immunocompromised Patients ◽  
Lymphoid Follicles ◽  
Negative Results ◽  
Immunosuppressed Patients ◽  
Life Threatening

Toxoplasmosis is generally asymptomatic in immunocompetent individuals, but it can be life-threatening in immunocompromised patients. We present a case of a 62-year-old man with clinical features of acute appendicitis. Histology showed a transmural infiltrate of eosinophils. In addition, there were reactive lymphoid follicles with histiocytes in the submucosa and tachyzoites in the muscularis propria. Immunohistochemistry confirmed the diagnosis of toxoplasma appendicitis. Serological evaluation yielded negative results. Retrospective review of the history revealed that the patient was on long-term immunosuppressive therapy with methotrexate. The patient was treated with sulfamethoxazole-trimethoprim and is asymptomatic at 7-month follow-up. Toxoplasma appendicitis must be considered in the differential diagnosis of appendicitis in immunosuppressed patients.

FIRST TIME EXPERIENCE OF COLD ATMOSPHERIC PLASMA USE IN MICROBIAL ECZEMA TREATMENT IN A 3-YEAR-OLD CHILD

2021 ◽  
Vol 100 (2) ◽  
pp. 292-295
Author(s):  
V.N. Korotkiy ◽  
◽  
M.I. Shemshuk ◽  
A.G. Rumyantsev ◽  
◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Ultraviolet Irradiation ◽  
Inflammatory Process ◽  
Clinical Observation ◽  
Bactericidal Effect ◽  
Atmospheric Plasma ◽  
Cold Atmospheric Plasma ◽  
Chronic Inflammatory Process ◽  
Time Experience ◽  
First Time

Microbial eczema (ME) is a chronic inflammatory process prone to recurrence, the treatment of which is associated with a number of difficulties due to the ever increasing antibiotic resistance of the microorganisms that cause it. Cold atmospheric plasma (CAP), like ultraviolet irradiation, has a pronounced bactericidal effect, but unlike the latter, it does not have undesirable effects on healthy cells. The article presents a clinical observation of the successful use of CAP in the treatment of severe ME in a 3-year-old child.

Mimics of acute appendicitis—Alternative diagnoses at sonography, CT, and MRI; specific imaging findings that can help in differential diagnosis

2018 ◽  
Vol 48 ◽  
pp. 90-105 ◽  
Author(s):  
Huseyin Toprak ◽  
Temel Fatih Yilmaz ◽  
Seyma Yildiz ◽  
Ihsan Turkmen ◽  
Serpil Kurtcan
Keyword(s):  
Differential Diagnosis ◽  
Acute Appendicitis ◽  
Imaging Findings ◽  
Ct And Mri

scholarly journals Laparoscopic Resection of a Giant Dedifferentiated Primary Retroperitoneal Mucinous Cystadenoma (PRMC) in a Young Woman: A Case Report and Literature Review

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Wu L ◽  
Li X ◽  
Li J ◽  
Lai Y
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Literature Review ◽  
Benign Tumor ◽  
Laparoscopic Resection ◽  
Abdominal Cavity ◽  
Mucinous Cystadenoma ◽  
Rare Benign Tumor ◽  
Primary Retroperitoneal

Background: PRMC is a very rare benign tumor of the abdominal cavity that usually occurs in women, and PRMC demonstrate no specific findings on CT. There are many reports on the differential diagnosis and discussion of PRMC imaging, but there are few reports on the treatment of dedifferentiated PRMC using laparoscopic resection and postoperative follow-up.

scholarly journals Experimental research on the origin of adhesions in the abdominal cavity after operations

2020 ◽  
Vol 5 (5) ◽  
pp. 504-507
Author(s):  
N. Aleksenko
Keyword(s):  
Experimental Research ◽  
Inflammatory Process ◽  
Abdominal Cavity ◽  
Abdominal Wound ◽  
Middle Line ◽  
Clinical Observations

Fusion of intestines and omentum after surgery, mainly with an abdominal wound, is a frequent phenomenon, proven by a number of clinical observations during repeated operations in the same subjects. Meanwhile, the question of the reasons for such a phenomenon, despite attempts to experimentally resolve it (Snger, Dembowski, Kelterborn), remains open to this day. According to the opinion of the last mentioned authors, the main cause of adhesions in the abdominal cavity after operations is infection, the accretion of the omentum to the middle line is caused by the release of air and the local inflammatory process; further - sloughing of the epithelium and scars of the peritoneum in uncomplicated cases do not give adhesions, ligatures in the abdominal cavity for the most part also do not cause adhesions, but show a tendency to encapsulate.

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