scholarly journals Randy Scholle's reaction (Med. Zh., 1922, no. 5)

2021 ◽  
Vol 18 (3) ◽  
pp. 105-106
Author(s):  
V. G.
Keyword(s):  
Infectious Disease ◽  
Central Nervous System ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Infectious Diseases ◽  
Test Tube ◽  
The Central Nervous System ◽  
Small Test ◽  
Carbolic Acid ◽  
Small Test Tube

The essence of this reaction, which occurs in all infectious diseases of the central nervous system, is as follows: to 1 cubic meter. site, concentrated (1:15) carbolic acid, poured into a small test tube, add 1 kyle of cerebrospinal fluid taken from a patient; if in this case there is an infectious disease of the central nervous system, then, due to the increased content of globulins in the cerebrospinal fluid, a smoky cloud of turbidity is formed in a few seconds throughout the contact of the drop falling to the bottom with the carbolic solution, while the normal liquid of this cloud does not give .

The Boltz (Acetic-Anhydride) Test in Cerebro-Spinal Fluid

1930 ◽  
Vol 76 (313) ◽  
pp. 271-276 ◽  
Author(s):  
C. Thomas
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Acetic Anhydride ◽  
Test Tube ◽  
Spinal Fluid ◽  
White Background ◽  
The Central Nervous System ◽  
Small Test ◽  
Small Test Tube ◽  
Pink Coloration

The acetic anhydride test was introduced in 1923 by Boltz, who regarded a positive result as diagnostic of syphilis of the central nervous system. The technique of the test is simplicity itself, and is as follows: Place 1 c.c. of spinal fluid in a small test-tube. Add 0.3 c.c. of acetic anhydride drop by drop; shake. Add 0.8 c.c. concentrated sulphuric acid drop by drop; shake. After five minutes examine the colour of the fluid against a white background. A lilac or blue-pink coloration is positive.

Takata-Aga reaction in the study of cerebrospinal fluid

1927 ◽  
Vol 23 (11) ◽  
pp. 1182-1182
Author(s):  
D. K. Bogoroditsky
Keyword(s):  
Central Nervous System ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Acid Solution ◽  
Test Tube ◽  
The State ◽  
The Central Nervous System

The technique of this reaction, suggested by two Japanese authors, Takata and Aga, in 1926, consists in adding 1 drop of a 10% Na carbonici solution and 0.3 of a freshly prepared mixture of equal parts 0.5% sulfa solution and 0.02% fuchsin (non-acid) solution to 1 cc of liquid. The mixture is shaken well and left in a test tube, and examined now after shaking, after h, after h, and after 24 h. Having tested this reaction in 60 patients, D.K. Bogoroditsky found that it is a very subtle indicator of the state of the central nervous system.

scholarly journals Dosage of lactate in the cerebrospinal fluid in infectious diseases of the central nervous system

2001 ◽  
Vol 59 (4) ◽  
pp. 843-848 ◽  
Author(s):  
Hideraldo Luis Souza Cabeça ◽  
Hélio Rodrigues Gomes ◽  
Luís dos Ramos Machado ◽  
José Antonio Livramento
Keyword(s):  
Central Nervous System ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Bacterial Meningitis ◽  
Infectious Diseases ◽  
Immune Deficiency Syndrome ◽  
Viral Meningitis ◽  
Control Group ◽  
Fungal Meningitis ◽  
The Central Nervous System

This paper analyzes the diagnosis aid of the dosage of lactate in the cerebrospinal fluid (CSF) in infectious diseases of the central nervous system (CNS). We analyzed prospectively 130 samples of CSF of 116 patients with diagnoses of infectious processes in the CNS. The 130 samples of CSF were divided into five groups: 28 samples of the control group, 40 of bacterial meningitis, 22 of viral meningitis, 16 of fungal meningitis and 24 of patients presenting acquired immune deficiency syndrome (AIDS). The concentration of lactate in the CSF was elevated in the group of patients with bacterial meningitis (average = 46.2 mg/dL), fungal meningitis (average = 27.3 mg/dL) and in the AIDS group (average = 23.5 mg/dL). In the control group and viral meningitis group the lactate content in the CSF presented the reference rates according to the employed method. The lactate dosage in the CSF presented a negative correlation with glycorrhachia and positive correlation with the cellularity and total proteins of the CSF. We conclude that the lactate dosage in the CSF, although unspecific, helps to distinguish the infectious processes of the CNS.

CHAPTER 9: Immunology of TBEV-Infections

2020 ◽  
Keyword(s):  
Central Nervous System ◽  
T Cells ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Nk Cells ◽  
Peripheral Blood ◽  
Sample Collection ◽  
Tick Borne Encephalitis ◽  
Viral Infectious Disease ◽  
The Central Nervous System

Tick-borne encephalitis (TBE) is a viral infectious disease of the central nervous system caused by the tick-borne encephalitis virus (TBEV). TBE is usually a biphasic disease and in humans the virus can only be detected during the first (unspecific) phase of the disease. Pathogenesis of TBE is not well understood, but both direct viral effects and immune-mediated tissue damage of the central nervous system may contribute to the natural course of TBE. The effect of TBEV on the innate immune system has mainly been studied in vitro and in mouse models. Characterization of human immune responses to TBEV is primarily conducted in peripheral blood and cerebrospinal fluid, due to the inaccessibility of brain tissue for sample collection. Natural killer (NK) cells and T cells are activated during the second (meningo-encephalitic) phase of TBE. The potential involvement of other cell types has not been examined to date. Immune cells from peripheral blood, in particular neutrophils, T cells, B cells and NK cells, infiltrate into the cerebrospinal fluid of TBE patients.

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