scholarly journals Cytological diagnosis of malignant tumors

2021 ◽  
Vol 43 (6) ◽  
pp. 80-81
Author(s):  
M. S. Sigal
Keyword(s):  
Malignant Tumors ◽  
Cytological Diagnosis ◽  
Cytological Diagnostics

The importance of cytological diagnostics in the recognition of cancer has been reflected in a number of reports.

scholarly journals PATHOMORPHOLOGICAL CHANGES IN THE ORGANS OF A CAT WITH ADENOCARCINOMA

2021 ◽  
Vol 247 (3) ◽  
pp. 70-74
Author(s):  
I.N. Zalyalov ◽  
◽  
E.N. Bulatova ◽  
I.S. Konstantinova ◽  
◽  
...  
Keyword(s):  
Statistical Data ◽  
Malignant Tumors ◽  
The Body ◽  
Cytological Diagnosis ◽  
Functional Disorders ◽  
Large Cities ◽  
Oncological Diseases ◽  
Domestic Carnivores ◽  
Oncological Pathology

Oncological diseases of unproductive animals are becoming increasingly common in veterinary practice, especially in large cities. The basis of tumor growth is the unlimited uncontrolled reproduction of cells by the body, which leads to a complex of structural and functional disorders. Despite the significant achievements of modern veterinary medicine in the field of diagnosis of benign and malignant tumors in animals, the issues of histological and cytological diagnosis of the forms of manifestation of this pathology remain problematic. Long-term statistical data show that there is a tendency to increase the incidence of oncological pathology in domestic carnivores, especially in the malignant form.

Operational cytological diagnostics in oncosurgery

1982 ◽  
Vol 63 (1) ◽  
pp. 7-9
Author(s):  
M. Z. Sigal ◽  
G. N. Khairutdinova
Keyword(s):  
Operational Research ◽  
Surgical Intervention ◽  
Cytological Diagnosis ◽  
Indications For Surgery ◽  
Histological Findings ◽  
Surgical Interventions ◽  
Operating Field ◽  
Puncture Biopsy ◽  
Cytological Diagnostics

Abstract. The informative value of urgent cytological operational research in various areas of oncosurgery has been studied. The data of these studies were summarized during 773 operations, including 424 laparotomies, 195 thoracotomies and 154 other surgical interventions. Histological control confirmed the reliability of cytological findings in 93.9%. In 11 cases of discrepancy between cytological and histological findings, the reliability of the cytological diagnosis was subsequently established. It is recommended to include data from puncture biopsy of various objects of the operating field as criteria for resolving questions about indications for surgery, the volume and plan of surgical intervention.

Using of immunocytochemistry in differential diagnosis of neoplasms of serosal cavities in dogs

2014 ◽  
Vol 17 (1) ◽  
pp. 149-159 ◽  
Author(s):  
R. Przeździecki ◽  
R. Sapierzyński
Keyword(s):  
Differential Diagnosis ◽  
Veterinary Medicine ◽  
Intermediate Filaments ◽  
Malignant Tumors ◽  
Small Animal ◽  
Mesothelial Cells ◽  
Cytological Diagnosis ◽  
Invasive Test ◽  
Strong Expression

Abstract The presence of tumor within the serosal cavities, often connected with accumulation of serosal effusion, is a quite common problem in the small animal veterinary medicine. The first step in diagnosis of such cases is cytopathological examination. The aim of the present study was to evaluate the usefulness of cytology and immunocytochemistry, using commercially available antibodies (anti-cytokeratin, anti-vimentin, and anti-desmin), in differential diagnosis of malignant tumors located within serosal cavities in dogs. The final cytological diagnosis of carcinoma/adenocarcinoma, sarcoma, and mesothelioma was obtained on the basis of routine cytopathology and immunocytochemistry, and then confirmed by histopathology and immunohistochemistry. Cytoplasmic immunoreactivitiy of normal mesothelid cells and cytoplasmic immunoreactivity of hyperplastic mesothelial cells revealed constant and strong expression of all examined intermediate filaments: cytokeratin, vimentin and desmin. Application of routine cytopathology and immunocytochemistry allowed 32 neoplastic tumors to be detected: 19 cases of carcinomas/adenocarcinomas, 6 cases of sarcomas, 7 cases of mesotheliomas. Immunostaining of cytopathological samples with chosen set of antibodies: anti-cytokeratin, anti-vimentin, anti-desmin is a useful, and low invasive test for differentiation between mesotheliomas and carcinomas/adenocarcinomas in dogs.

scholarly journals Cysticercosis breast: a cytological diagnosis

2018 ◽  
Vol 4 (9) ◽  
pp. 238
Author(s):  
Jyoti Rajpoot ◽  
Sheetal Arora ◽  
Nikita Gupta ◽  
Rashmi Arora
Keyword(s):  
Malignant Tumors ◽  
Taenia Solium ◽  
Needle Aspiration ◽  
Oral Route ◽  
Cytological Diagnosis ◽  
Larval Form ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Case Diagnosis

<p class="abstract">Parasitic lesions of breast are rare, usually seen in endemic areas. Clinically such cases are frequently misdiagnosed as benign or sometimes malignant tumors of breast. Cysticercosis is caused by larval form of Taenia solium, acquired via fecal oral route. Radiology may be suggestive of cysticerocosis. In our case, diagnosis was confirmed with fine needle aspiration cytology.</p>

scholarly journals A CASE OF ORAL MUCOSAL MALIGNANT MELANOMA IN DISGUISE OF CERVICAL METASTATIC LYPMHADENOPATHY WITH APPARENTLY UNKNOWN PRIMARY.

2015 ◽  
Vol 23 (3) ◽  
pp. 129-133
Author(s):  
Somesh Mozumder ◽  
Shirish Dubey ◽  
Aniruddha Dam ◽  
Anup Kumar Bhowmick
Keyword(s):  
Malignant Melanoma ◽  
Malignant Tumors ◽  
Cervical Lymphadenopathy ◽  
Whole Body ◽  
Unknown Primary ◽  
Cytological Diagnosis ◽  
Pigmented Lesions ◽  
18Fdg Pet ◽  
Pet Ct ◽  
Mucosal Malignant Melanoma

Introduction: Primary malignant melanoma of the oral cavity is a rare neoplasm. The tumors tend to metastasize or locally invade tissue more readily than other malignant tumors in the oral region. Case Report: A 55 year old male presented with left sided hard cervical lymphadenopathy with unknown primary with cytology of malignant melanoma. 18FDG-PET-C.T scan helped identification of the primary. Discussion: The survival of patients with mucosal melanomas is less than for those with cutaneous melanomas. Tumor size and metastases are related to the prognosis of the disease. Early oral malignant melanomas can be clinically very difficult to distinguish from other benign oral pigmented lesions. Conclusion:  Any case presenting with cervical lymphadenopathy with a cytological diagnosis of Malignant Melanoma and without clinically identifiable primary, early detection using whole body 18FDG-PET CT is utmost important.

CYTOLOGICAL DIAGNOSTICS OF INTRAOPERATIVE PERITONEAL WASHES IN GASTRIC CANCER

2019 ◽  
Vol 64 (4) ◽  
pp. 225-228
Author(s):  
M. V. Putova ◽  
K. K. Noskova ◽  
B. A. Pomortsev ◽  
N. E. Semenov ◽  
R. E. Izrailov
Keyword(s):  
Stomach Cancer ◽  
High Tech ◽  
Cytological Diagnosis ◽  
Block Method ◽  
Cytological Examination ◽  
Preoperative Stage ◽  
Peritoneal Washings ◽  
Immunocytochemical Techniques ◽  
Cancer Laparoscopy ◽  
Cytological Diagnostics

Diagnosis of peritoneal microcanceromatosis is the most important task allowing to determine treatment strategy for patients with stomach cancer. Laparoscopy combined with peritoneal flushing and subsequent cytological examination should be performed to detect the peritoneal microcanceromatosis at the preoperative stage. The objective of this work was to improve cytological diagnostics of peritoneal washings using immunocytochemical techniques and the cell block method. The work was carried out on the basis of 276 surgical peritoneal washings in patients with stomach cancer who were on treatment in the department of high-tech surgery of the Moscow Clinical Scientific Centre of the State Budgetary Healthcare Institution named after Loginov A.S. from June 2016 to June 2018. As a result, the optimal panel of monoclonal antibodies (Ber-EP4, CEA, CK20) was chosen, which increased the sensitivity from 52% to 96% and the specificity of cytological diagnosis from 80% to 98%, and the overall accuracy of the method from 67% to 98%.

The application of electron microscopy to diagnosis in gynecologic neoplasms and tumor-like conditions

1984 ◽  
Vol 42 ◽  
pp. 102-105
Author(s):  
Lawrence M. Roth
Keyword(s):  
Electron Microscopy ◽  
Reproductive Tract ◽  
Malignant Tumors ◽  
Frozen Section ◽  
Cost Effective ◽  
Female Reproductive Tract ◽  
Ultrastructural Examination ◽  
Specific Diagnosis ◽  
Potential Value ◽  
Gynecologic Neoplasms

The female reproductive tract may be the site of a wide variety of benign and malignant tumors, as well as non-neoplastic tumor-like conditions, most of which can be diagnosed by light microscopic examination including special stains and more recently immunoperoxidase techniques. Nevertheless there are situations where ultrastructural examination can contribute substantially to an accurate and specific diagnosis. It is my opinion that electron microscopy can be of greatest benefit and is most cost effective when applied in conjunction with other methodologies. Thus, I have developed an approach which has proved useful for me and may have benefit for others. In cases where it is deemed of potential value, glutaraldehyde-fixed material is obtained at the time of frozen section or otherwise at operation. Coordination with the gynecologic oncologist is required in the latter situation. This material is processed and blocked and is available if a future need arises.

Ultrastructure of Cryptorchidism and Seminoma

1981 ◽  
Vol 39 ◽  
pp. 540-541
Author(s):  
Shirley Siew ◽  
Susan C. James
Keyword(s):  
Malignant Tumors ◽  
Frozen Section ◽  
Malignant Potential ◽  
Genetic Influences ◽  
Endocrine Gland ◽  
Medial Aspect ◽  
Left Testis ◽  
Bilateral Orchiectomy

Testicular maldescent is the most common endocrine gland abnormality, as 2.7% of mature neonates are cryptorchid. The significant complications are that there is a disturbance of normal maturation which results in diminished fertility and there is an increase in the malignant potential which is 35 times greater in the undescended than the descended testis. It is considered that genetic influences may be of etiological importance and recurrence has been described in some families. It is of interest, that the case reported here has 2 siblings who have also presented with cryptorchidism and malignant tumors.The propositus is 14 years old. He is well developed (described by some as obese) and shows normal secondary male characteristics except for an immature scrotum. Laparotomy showed both testes to be intraabdominal. A hard nodule (0.5cm) was palpated on the medial aspect of the left testis. Frozen section showed the presence of seminoma and bilateral orchiectomy was performed.

Hepatocyte ultrastructural alterations in perimetastatic areas

1996 ◽  
Vol 54 ◽  
pp. 768-769
Author(s):  
H. J. Finol ◽  
M. E. Correa ◽  
L.A. Sosa ◽  
A. Márquez ◽  
N.L. Díaz
Keyword(s):  
Malignant Tumor ◽  
Malignant Tumors ◽  
Surrounding Tissue ◽  
Ultrastructural Changes ◽  
Pancreas Carcinoma ◽  
Duct Carcinoma ◽  
Tissue Samples ◽  
Primary Malignant Tumor ◽  
Transmission Electron ◽  
Remote Sites

In classical oncological literature two mechanisms for tissue aggression in patients with cancer have been described. The first is the progressive invasion, infiltration and destruction of tissues surrounding primary malignant tumor or their metastases; the other includes alterations produced in remote sites that are not directly affected by any focus of disease, the so called paraneoplastic phenomenon. The non-invaded tissue which surrounds a primary malignant tumor or its metastases has been usually considered a normal tissue . In this work we describe the ultrastructural changes observed in hepatocytes located next to metastases from diverse malignant tumors.Hepatic biopsies were obtained surgically in patients with different malignant tumors which metatastized in liver. Biopsies included tumor mass, the zone of macroscopic contact between the tumor and the surrounding tissue, and the tissue adjacent to the tumor but outside the macroscopic area of infiltration. The patients (n = 5), 36–75 years old, presented different tumors including rhabdomyosarcoma, leiomyosarcoma, pancreas carcinoma, biliar duct carcinoma and colon carcinoma. Tissue samples were processed with routine techniques for transmission electron microscopy and observed in a Hitachi H-500 electron microscope.

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