scholarly journals Cerebral hemodynamics in atherosclerotic discirculatory encephalopathy of different expressiveness

1998 ◽  
Vol XXX (1-2) ◽  
pp. 12-15
Author(s):  
B. A. Osetrov ◽  
L. V. Salysheva ◽  
A. A. Komissarenko

In 260 patients with cerebral circulatory insufficiency of different expressiveness the state of linear cerebral blood stream was determined by method of cerebral radiocirculography. For integral evaluation of the state of cerebral blood supply effectiveness ratio of linear blood flow in blood supply was calculated. Complete parallelism between clinical manifestations of cerebral artherosclerosis and expressiveness of disorders of cerebral blood flow has not been revealed. In patients with discirculatory encephalopathy of stage I blood flow by cerebral vessels is lowered when reducing cerebral blood supply. Blood flow is prevailing in the left hemisphere. In patients with discirculatory encephalopathy of stage II in cerebral blood supply retrograde venous support is revealed, allowing to maintain vascular blood supply at a relatively high level. Intersemispheric hemodynamic differences are being smoothed. Discirculatory encephalopathy of stage III is characterized by sharp worsening of cerebral hemodynamics. Supply level in the left cerebral hemisphere appears to be at a lower level, than in the right one. During further pathology development hemodynamic disorders achieve a critical level, beyond which vascular catastophe or death occurs.

2020 ◽  
Vol 22 (4) ◽  
pp. 647-663
Author(s):  
Vasily K. Pinkevich

The purpose of the article is to trace the connection between the change in the religious policy of the state and the anti-clerical protests of the 2016-2020s. Statements against Church restitution and the construction of churches have caused extensive discussion, which has given rise to a number of contradictory, sometimes mutually exclusive interpretations. According to the author, the reason for these protests was not private reasons, but deeper reasons related to the religious policy of the state. The author pays special attention to changes in religious legislation, which led to increased control over the private life of citizens and infringement of the right to freedom of ideological choice. The article points out that the religious issue has divided Russian society: the ruling class on the one hand, and a significant part of citizens on the other, have become increasingly different in understanding the place and role of religion in the life of the country. According to the author, the protests in Yekaterinburg, St. Petersburg, and Moscow were special cases of numerous manifestations of politicization of society and growing dissatisfaction with the state of state-confessional relations in modern Russia. The author concludes that the degree of conflict, the high level of solidarity actions, a diverse and resonant series of events, as well as the level of ideological discussion allow us to classify these events as political and plebiscite.


1997 ◽  
Vol XXIX (3-4) ◽  
pp. 39-42
Author(s):  
A. A. Mikhailenko ◽  
М. М. Odinak ◽  
I. А. Voznjuk

By methods of extra- and transcranial dopplerography, reoencephalography evaluation of correspodence of brain hemoperfusion and reserves of autoregulation during rest and functional tests in patients was carried out with early manifestations of insufficient blood supply of brain. For this purpose 114 patients with such disease and 70 healthy people were examined. The most diagnostic significance for revealing disorders of cerebral hemodynamics in people with early manifestations of ischemic lesion of brain, have alterations of values of linear blood flow speed, range of cerebrovascular reactivity, values of circulation resistance. They indicate adequacy of hemoperfusion, presence of stenosis and intracerebral overdistribution of circulating blood. Pathogenetic variants of insufficient cerebral blood supply are shown in the verterbrobasilar basin.


Author(s):  
G.B. Nazarenko ◽  
T.S. Heilo

A method for diagnosing and monitoring the patient’s general condition has been developed, including the use of the specially developed and registered for clinical use of the device OKO Capillaroscope for non-invasive, non-contact video recording under a large increase in blood flow in the human bulbar conjunctival microvessels using special software that allows: measuring movement speed erythrocytes in individual arterioles, venules, and in the main preferred channels; to fix in microvessels the possible presence of sludge syndrome, stasis of the erythrocyte movement; to assess the number and shape of capillaries, the presence of arteriolar-venular anastomoses, the identity of blood flow in the microvessels of the conjunctiva in the right and left eye; measure arteriole diameters and venules. The method is aimed at a clinical study of the parameters of the microcirculation of the conjunctiva at rest, which allows extrapolating the recorded parameters of the intravascular (rheological) part of the microcirculation system to the state of the microhemodynamics of the whole organism, which reflects the state of general homeostasis. The method can be applied to control and monitor the general condition of a person or patient in any research in experimental, sports or therapeutic purposes, since the determined digital parameters of microcirculation allow to assess the general condition of a person, the response to physical exertion and evaluate the completeness and completeness of therapeutic treatment in various pathologies due to somatic or local degenerative changes in the patient’s body.


Author(s):  
G.B. Nazarenko ◽  
T.S. Heilo

A method for diagnosing and monitoring the blood microcirculation state has been developed, including the use of the specially developed and registered for clinical use of the device OKO Capillaroscope for non-invasive non-contact video recording under a large increase in blood flow in the microvessels of the bulbar conjunctiva of the human eye using special software that allows: to measure the speed of red blood cells in individual arterioles, venules and in the main preferred channels; to fix in the microvessels the possible presence of sludge syndrome, stasis of the erythrocyte movement; to evaluate the number and shape of capillaries, the presence of arteriolar-venular anastomoses, the identity of blood flow in the microvessels of the conjunctiva in the right and left eyes; measure arteriole diameters and venules. The method is aimed at a clinical study of the parameters of the microcirculation of the conjunctiva at rest, which allows extrapolating the recorded parameters of the intravascular (rheological) part of the microcirculation system to the state of the microhemodynamics of the whole organism, which reflects the state of general homeostasis. The method can be applied to control and monitor the general condition of a person or patient in any research in experimental, sports or therapeutic purposes, since the determined digital parameters of microcirculation allow to assess the general condition of a person, the response to physical activity and predict the development of any general or local degenerative changes in the patient’s body.


2021 ◽  
Vol 66 ◽  
pp. 118-122
Author(s):  
T. A. Masalova

The article considers the issues of guarantees of protection of the policeman's right to financial security, in particular, the definition of "guarantees of protection of the policeman's right to financial security", defines the purpose, objectives and functions of the investigated guarantees, and outlines the structure of basic guarantees. Thus, guarantees for the protection of the right of police officers to financial security are considered as a set of legal and organizational-legal means, methods and conditions by which the police and state bodies ensure the real restoration of the violated right to remuneration. It is concluded that today the guarantees of protection of the police officer's right to monetary security are a special manifestation of guarantees of protection of the employee's right to remuneration. This position allows us to draw the following conclusions: (1) the extension to the police of labor law and other guarantees of protection of labor rights of employees contributes to the expansion of the set of human-centered principles available in labor law in this area. This does not allow the state to subject police officers to labor exploitation, which degrades their human dignity, and obliges them to properly ensure and protect the right of these officers to a decent reward for their work; (2) as the real existence of guarantees of human and civil rights and freedoms in Ukraine is still far from adequate, the guarantees of protection of the police officer's right to financial security are not sufficiently perfect. Meanwhile, it should be borne in mind that the importance of police work, as well as ensuring a high level of social security of these officers has led to the creation and operation of a legal mechanism to protect the right of police officers to a decent reward. conditions under which a police officer may confirm and protect the right to financial security by all means and methods available to him, which do not endanger the state of national security of the state.


2017 ◽  
Vol 7 (4) ◽  
pp. 39-43 ◽  
Author(s):  
Valentin N Krupin ◽  
Alexey V Krupin ◽  
Anna N Belova ◽  
Natalya A Nashivochnikova

The aim of this study was to evaluate the state of blood flow in prostate in 59 men with chronic pelvic pain due to myofascial syndrome in the absence of clinical manifestations of chronic prostatitis and its dynamics against the background of the treatment. The results of the study revealed a reliable relationship between the severity of blood flow disorders in the prostate and the intensity of pain symptoms caused by myofascial syndrome. It was concluded that the hemodynamic disorders of the prostate caused by myofascial syndrome are important in the possible formation of clinical symptoms of chronic pelvic pain in men. (For citation: Krupin VN, Krupin AV, Belova AN, Nashivochnikova NA. The state of prostate hemodynamics in patients with myophascial pain syndrome. Urologicheskie vedomosti. 2017;7(4):39-43. doi: 10.17816/uroved7439-43).


Introduction. The article is devoted to the issue of determining the role and place of the bar in the state. The urgency of this issue was a consequence of the adoption in June 2016 of the Law of Ukraine "On Amendments to the Constitution of Ukraine (regarding justice)" of 02.06.2016 № 1401-VIII. Summary of the main research results. According to which the Constitution of Ukraine was supplemented by Article 131-2, which stipulates that the bar operates in Ukraine to provide professional legal assistance, and only a lawyer represents another person in court, as well as protection from criminal charges, except in certain cases. Thus, the bar, together with the prosecutor's office, was included in the justice system. Thus, the bar becomes one of the key elements of the justice system in Ukraine, as the most important constitutional function of the bar is to ensure the right to protection from criminal prosecution and representation of individuals and legal entities in court. By delegating the relevant function of the bar, the state must ensure a high level of professional legal assistance provided by lawyers, which, in turn, has a significant impact on the quality of justice and the exercise of the right to a fair trial. By delegating the relevant function of the bar, the state must ensure a high level of professional legal assistance provided by lawyers, which, in turn, has a significant impact on the quality of justice and the exercise of the right to a fair trial. At the same time, the Constitution of Ukraine provides for the independence of the bar, and the current Law of Ukraine "On Advocacy and Advocacy" generally indicates that the Bar of Ukraine is a non-governmental self-governing institution. Conclusions. The Ukrainian Bar is a professional public association. The National Bar Association of Ukraine is recognized as a non-governmental non-profit professional organization. In turn, the bar is endowed with public law functions, and the inclusion of non-state actors in the system of public power is designed to create an effective mechanism of public control over the activities of the state.


2017 ◽  
Vol 30 (1) ◽  
pp. 42-70
Author(s):  
S Viljoen

In 2014, a year supposedly marked to celebrate twenty years of democracy and the transformation of our housing regime from one being grossly discriminatory to a welfare-orientated legal system that functions under the auspices of the rights and values entrenched in the Constitution the poorest households in South Africa remain subject to not only intolerable housing conditions, but also unlawful state evictions. The housing jurisprudence has developed certain indicators of the state’s constitutional obligations and these indicators constitute the courts’ conception of its expectations of the state in complex housing disputes that generally concern homelessness/landlessness. However, recent state actions taken in contravention of section 26 indicate the systemic violation of the right to the extent that it is deprived of all meaning. With the required cognisance of the courts’ inherent competencies, concerns for separation of powers boundaries and an inclination to maintain a high level of deference in polycentric matters with economic and social consequences for the community, the courts are obliged to hold government accountable and vindicate the violation of fundamental rights. A form of reparation is therefore required that is able to address these violations in a systemic manner, without usurping the functions of the executive. Structural relief is apt in such instances, provided that it is structured in a specific manner to address immediate and long-term housing needs in a way consistent with other constitutional provisions and the underlying values of the Constitution. A once-off form of relief is inappropriate to counter the systemic violation of the right of access to adequate housing.On the other hand, a structural interdict is different to the extent that it can consist of different remedial phases over which the court retains jurisdiction to ensure that the state complies with its section 26(2) obligations. Throughout this process of supervision the court should encourage a dialogue between the different stakeholders and assist with predeterminations of the kinds of governmental actions that would be unreasonable, procedurally unfair and generally in contravention of the Constitution.


2016 ◽  
Vol 311 (4) ◽  
pp. H972-H980 ◽  
Author(s):  
Andreas Polycarpou ◽  
László Hricisák ◽  
András Iring ◽  
Daniel Safar ◽  
Éva Ruisanchez ◽  
...  

Cerebral circulation is secured by feed-forward and feed-back control pathways to maintain and eventually reestablish the optimal oxygen and nutrient supply of neurons in case of disturbances of the cardiovascular system. Using the high temporal and spatial resolution of laser-speckle imaging we aimed to analyze the pattern of cerebrocortical blood flow (CoBF) changes after unilateral (left) carotid artery occlusion (CAO) in anesthetized mice to evaluate the contribution of macrovascular (circle of Willis) vs. pial collateral vessels as well as that of endothelial nitric oxide synthase (eNOS) to the cerebrovascular adaptation to CAO. In wild-type mice CoBF reduction in the left temporal cortex started immediately after CAO, reaching its maximum (−26%) at 5–10 s. Thereafter, CoBF recovered close to the preocclusion level within 30 s indicating the activation of feed-back pathway(s). Interestingly, the frontoparietal cerebrocortical regions also showed CoBF reduction in the left (−17–19%) but not in the right hemisphere, although these brain areas receive their blood supply from the common azygos anterior cerebral artery in mice. In eNOS-deficient animals the acute CoBF reduction after CAO was unaltered, and the recovery was even accelerated compared with controls. These results indicate that 1) the Willis circle alone is not sufficient to provide an immediate compensation for the loss of one carotid artery, 2) pial collaterals attenuate the ischemia of the temporal cortex ipsilateral to CAO at the expense of the blood supply of the frontoparietal region, and 3) eNOS, surprisingly, does not play an important role in this CoBF redistribution.


Author(s):  
Christian J. Kähler ◽  
Thomas Fuchs ◽  
Benedikt Mutsch ◽  
Rainer Hain

OverviewThe future belongs to children and they need education to shape the future with foresight and intention. Children therefore have the right to education, according to Article 29 of the UN Convention on the Rights of the Child [1]. However, professional education is not everything, because children must also experience their strengths and weaknesses together and educate each other to be responsible and considerate people, so that they become socially valuable personalities. Only in this way can they shape the future in a peaceful and humane way. Therefore, attending school is essential. However, children also have the right to protection and care by their parents and the state, because the welfare of the child must also be given priority in accordance with Article 3 of the UN Convention on the Rights of the Child. The question is therefore how schooling in community schools can be realized during the SARS-CoV-2 pandemic without exposing children to an unnecessary risk of infection. It is not only about the children, because if the children are at risk, then so are their parents and grandparents and ultimately society as a whole. There are numerous concepts that promise safety in schools during the pandemic. When selecting concepts, the costs must of course be weighed against the benefits. People rightly expect an efficient use of resources. This means that either the set goal is achieved with the least possible resources or that the available resources are used to achieve the greatest possible approximation to the goal. In addition to the financial resources, however, the long-term consequences for the state, the economy, the population and the environment under the pressure of the pandemic must also be taken into account. Social cohesion and democracy must not be jeopardized either. Various protection concepts are currently under discussion. Often the advantages are overstated and the disadvantages concealed. Furthermore, some arguments are based on assumptions that are not true. The aim of this study is to provide a comparative assessment of the main protection concepts and to demonstrate, with the help of experimental analyses, the extent to which the protection concepts are effective. We will show that a comparatively high level of safety against infection in classrooms can be technically ensured without exposing children to masks. At the same time, the protection concept makes economic sense and the burden on the environment is comparatively low, so that infection prevention and climate protection do not have to be weighed against each other, because infection prevention and climate protection are political and social goals that have to be achieved together.


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