scholarly journals FULL TERM BABIES; CORRELATION OF CLINICAL FINDINGS OF PERINATAL ASPHYXIA WITH CRANIAL SONOGRAPHY

2017 ◽  
Vol 24 (06) ◽  
pp. 828-833
Author(s):  
ABDUR REHMAN MALIK ◽  
AHMED IQBAL QUDDUSI ◽  
NAZIA FATIMA ◽  
IMRAN IQBAL ◽  
AZHAR MEHMOOD JAVEED
Keyword(s):  
Perinatal Asphyxia ◽  
Clinical Findings ◽  
Full Term ◽  
Cranial Sonography

scholarly journals FULL TERM BABIES;

2017 ◽  
Vol 24 (06) ◽  
pp. 828-833
Author(s):  
Abdur Rehman Malik ◽  
Ahmed Iqbal Quddusi ◽  
Nazia Fatima ◽  
Imran Iqbal ◽  
Azhar Mehmood Javeed
Keyword(s):  
Birth Weight ◽  
Neonatal Intensive Care ◽  
Perinatal Asphyxia ◽  
Full Term ◽  
P Value ◽  
Cranial Ultrasound ◽  
Positive Correlation ◽  
Cranial Sonography ◽  
History Of ◽  
Moderate Positive Correlation

Introduction: Perinatal asphyxia is one of the most common causes of neonatalmorbidity and mortality in most countries of the world. The objective of my study was to assessthe correlation of clinical findings of perinatal asphyxia with cranial sonography in full termbabies. Study Design: Retrospective study. Setting: Neonatal Intensive Care Unit of Children’sHospital Multan. Period: January 2016 to October 2016. Material and Methods: 100 fullterm babies having history of delayed cry were scanned within three days of birth in NeonatalIntensive Care Unit of Children’s Hospital Multan. Clinically findings including full term babies,birth weight, grunting, cyanosis history of mode delivery, resuscitation history, delayed cry andhypoxic ischemic encephalopathy (HIE) grades were taken from baby’s hospital file record andstandard images including coronal and sagittal plans were taken by Ultrasound machine probeof frequency 3-5 MHz. Findings were recorded on data collection sheets and spread on EXELsheets. Correlation was found by using SPSS software. Result: Out of 100 neonates 63 weremale and 37 were female with birth weight (2.4-3.6) having mean ± SD 3.08 ± 0.53. HIE grades(mild, moderate and severe) were found in 12, 83, 5 babies respectively and ultrasound grades0 (normal/ mild echogenic), grade 1 (moderate echogenic) and grade 2 (severe/generalizedechogenic) were found in 32, 52, 16 neonates respectively with r= 0.37 and P-value < 0.05showing moderate positive correlation. Conclusion: Cranial ultrasound is a good screeningtool to evaluate asphyxiated neonatal brain. It has a moderate positive correlation with clinicalfindings.

scholarly journals Respiratory distress in Full and Post term neonates: Prevalence, Etiologies and Outcomes in a Tertiary Health Center in Yaoundé

2020 ◽  
Author(s):  
Didi Stanine Mefo Kue ◽  
Aude Sabine Nanfack ◽  
ANNE ESTHER NJOM NLEND
Keyword(s):  
Mortality Rate ◽  
Respiratory Distress ◽  
Health Center ◽  
Perinatal Asphyxia ◽  
Clinical Signs ◽  
Respiratory Control ◽  
Neonatal Infection ◽  
Full Term ◽  
Cross Sectional ◽  
Term Neonates

Abstract Introduction Respiratory distress (RD) is a common condition for admission of newborns in neonatal care unit (NCU), in both preterm and full-term neonates. Our objective was to describe the clinical features, causes and treatment of RD in full term neonates in a tertiary health center in Yaoundé, the Essos Hospital Centre (EHC). Patients and Method We conducted a cross sectional retrospective study. Full term neonates with RD at EHC from January 2017 to December 2018 were included, assuming clinical signs of RD prior to 48 hours following admission. Factors evaluated: incidence of RD, main etiologies, short term outcomes and risk factors for severity. Data were collected using a chart, then analyzed using software Stata Version 13.Results 186 full term neonates out of 2312 newborn babies admitted in NCU, met the inclusion criteria giving a prevalence rate of RD of 8%. Sex ratio of 2.15 was favoring males; median age at admission was 7.25 hours and 89.2 % were born at a median gestational age of 38 weeks. Clinical signs of RD were dominated by signs of respiratory control with a Silverman score above 4/10 in 64%. The most common etiologies were neonatal infection / pneumonia (45.9%), followed by transient tachypnea. Clinical management was performed using nasal cannula oxygen and antibiotics. Perinatal asphyxia, cyanosis and caesarian section were found to be associated with severe RD in this setting. Mortality rate was 10.4%.Conclusion RD in full term neonates is common in this setting, with neonatal infection as preeminent etiology; the mortality rate is high and the management still inappropriate.

General Movements in Full-Term Infants with Perinatal Asphyxia Are Related to Basal Ganglia and Thalamic Lesions

2011 ◽  
Vol 158 (6) ◽  
pp. 904-911 ◽  
Author(s):  
Fabrizio Ferrari ◽  
Alessandra Todeschini ◽  
Isotta Guidotti ◽  
Miriam Martinez-Biarge ◽  
Maria Federica Roversi ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Perinatal Asphyxia ◽  
Full Term ◽  
Term Infants ◽  
Thalamic Lesions ◽  
General Movements

Correlation between computed tomography and autopsy in premature and full-term neonates that have suffered perinatal asphyxia.

Radiology ◽  
1980 ◽  
Vol 137 (1) ◽  
pp. 93-103 ◽  
Author(s):  
O Flodmark ◽  
L E Becker ◽  
D C Harwood-Nash ◽  
P M Fitzhardinge ◽  
C R Fitz ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Perinatal Asphyxia ◽  
Full Term ◽  
Term Neonates

scholarly journals Study of dynamics of lactate dehydrogenase and hepatic enzymes activity following perinatal asphyxia in full term neonates

2016 ◽  
Vol 3 (9) ◽  
pp. 697-704
Author(s):  
Dr Deepthi Ramu ◽  
◽  
Dr Prashanth Madapura.V ◽  
Dr Sarala Sabapathy ◽  
Dr Nidhi Rajendra ◽  
...  
Keyword(s):  
Lactate Dehydrogenase ◽  
Perinatal Asphyxia ◽  
Full Term ◽  
Hepatic Enzymes ◽  
Term Neonates ◽  
Enzymes Activity

scholarly journals Clinical Investigations: Somatosensory Evoked Potentials in Full-Term Neonates With Perinatal Asphyxia

Folia Medica ◽  
2014 ◽  
Vol 56 (2) ◽  
pp. 88-95 ◽  
Author(s):  
Ina E. Geneva ◽  
Maya B. Krasteva ◽  
Stefan S. Kostianev
Keyword(s):  
Evoked Potentials ◽  
Somatosensory Evoked Potentials ◽  
Amplitude Ratio ◽  
Perinatal Asphyxia ◽  
Nerve Fibers ◽  
Full Term ◽  
Healthy Children ◽  
Term Infants ◽  
Healthy Infants ◽  
Term Newborns

Abstract OBJECTIVE: To explore the capacity of somatosensory evoked potentials (SEP) to assess maturation processes in the development of the nervous system, and the characteristics of SEP in healthy full-term infants and full-term newborns with perinatal asphyxia and their follow up until the age of 14 months. MATERIALS AND METHODS: SEP were studied in 21 healthy full-term infants and 38 full-term newborns with perinatal asphyxia. The children with asphyxia were studied longitudinally until they were 14 months old. To assess the SEP we measured the latency of the P15, N20 and P25 components, the amplitude ratio N20/ P25 and inter-peak intervals P15-N20 and N20-P25. RESULTS: The component that was most typically always found in the SEP recordings of both healthy infants and those with perinatal asphyxia was N20. The mean latency values of P15, N20 and P25 were higher in the children with perinatal asphyxia (p ⋋ 0.001). The SEP amplitude was highly variable (CoV% = 76.6%). The latencies became shorter with age in asphyxia patients aged 0 to 14 months, the shortening being the greatest in the first trimester, while they showed no statistically significant differences in infants aged 6 to 12 months. CONCLUSIONS: SEPs in the neonatal period differ considerably from those of adults and older children in the morphology and longer potential latency, which can be accounted for by the incomplete myelination of nerve fibers. The changes in SEP latency in patients with HIE stages I and II follow the same pattern found in healthy children - latency became shorter with increasing age, which was most pronounced in the first 3 months. SEP latency was found to be correlated with height and age. No differences were found in the latency of potentials between healthy infants and infants with brain hemorrhage. Recording SEP is a sensitive method to assess the CNS in children with perinatal asphyxia and to monitor the maturation of the somatosensory pathway.

Thromboelastometry Variables in Neonates with Perinatal Hypoxia

2020 ◽  
Vol 46 (04) ◽  
pp. 428-434 ◽  
Author(s):  
Aikaterini Konstantinidi ◽  
Rozeta Sokou ◽  
Andreas G. Tsantes ◽  
Stavroula Parastatidou ◽  
Stefanos Bonovas ◽  
...  
Keyword(s):  
Perinatal Asphyxia ◽  
Fetal Distress ◽  
Clinical Findings ◽  
Perinatal Hypoxia ◽  
Clotting Factors ◽  
Increased Risk ◽  
Neonatal Liver ◽  
Coagulation Status ◽  
Α Angle

AbstractPerinatal hypoxia is associated with an increased risk of coagulation disorders by enhancing the consumption of platelets and some clotting factors due to the associated severe hypoxemia, acidemia, and compromised oxygen and blood supply to the neonatal liver and bone marrow. Thromboelastometry (TEM), which estimates the dynamics of blood coagulation, may represent an attractive tool for studying the coagulation status of these neonates. We aimed at assessing the hemostatic profile of neonates with perinatal hypoxia using the standard extrinsically activated TEM (ex-TEM) assay. In total, 164 hospitalized neonates with perinatal asphyxia and/or fetal distress comprised the study subjects, and 273 healthy neonates served as controls. Ex-TEM assay was performed, SNAPPE (Score for Neonatal Acute Physiology Perinatal Extension) was calculated, and clinical findings and laboratory results were recorded in all study subjects. Hypoxic neonates expressed a prolonged clotting time (CT) and clot formation time (CFT) and reduced amplitude at 10 minutes (A10), α-angle, and maximum clot firmness compared with healthy neonates. Furthermore, asphyxiated neonates had a significantly prolonged CT and CFT and reduced A10 and α-angle compared with neonates with fetal distress. Hypoxic neonates demonstrate a hypocoagulable ex-TEM profile relative to healthy neonates, indicating a potential role of TEM in the early detection of coagulation derangement in perinatal hypoxia.

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