Novel Conversion of 4-Aminoquinolines to New Tricyclic (R,S)-3-Methylazeto[3,2-c] Quinolin-2(2aH)-Ones and Versatile One Step Synthesis of N-(Quinolin-4-yl) Carbamates from 4-Aminoquinolines

International Letters of Chemistry Physics and Astronomy ◽

10.18052/www.scipress.com/ilcpa.30.265 ◽

2014 ◽

Vol 30 ◽

pp. 265-276

Author(s):

Vipul C. Kotadiya ◽

Denish J. Viradiya ◽

Bharat H. Baria ◽

Jayendra S. Kanzariya ◽

Rajesh Kakadiya ◽

...

Keyword(s):

Chemical Methods ◽

One Step ◽

Alkyl Chloroformates

Reaction of 4-aminoquinolines with 4-nitrophenyl chloroformate have resulted in finding a novel transformation of 4-aminoquinolines to tricyclic (R,S)-3-methylazeto[3,2-c]quinolin-2(2aH)-ones. The structure of azeto-quinolinone was determined via spectroscopic and chemical methods. Various alcohols were used as nucleophiles to open the 1-azetinone ring to give the corresponding N-(quinolin-4-yl)carbamates in good yields. We also found a new and versatile one step synthesis of N-(quinolin-4-yl)carbamates by reacting 4-aminoquinolines with alkyl chloroformates in the presence of anhyd K2CO3 in acetonitrile.

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The ultimate step towards a tailored engineering of core@shell and core@shell@shell nanoparticles

Nanoscale ◽

10.1039/c4nr02913e ◽

2014 ◽

Vol 6 (22) ◽

pp. 13483-13486 ◽

Cited By ~ 61

Author(s):

D. Llamosa ◽

M. Ruano ◽

L. Martínez ◽

A. Mayoral ◽

E. Roman ◽

...

Keyword(s):

Building Blocks ◽

Core Shell ◽

Chemical Methods ◽

Shell Nanoparticles ◽

The Core ◽

One Step ◽

Step Generation ◽

The One

Core@shell and core@shell@shell nanoparticles are building blocks for more sophisticated systems and a plethora of applications. The one-step generation of such complex nanoparticles is reported where the atoms of the core and shell can be easily inverted, avoiding intrinsic constraints of chemical methods.

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BENTONITE PILLARED BY MESOPOROUS SILICA AND ITS APPLICATION FOR GASOLINE TREATMENT

Vietnam Journal of Science and Technology ◽

10.15625/2525-2518/55/5b/12222 ◽

2018 ◽

Vol 55 (5B) ◽

pp. 164

Author(s):

Vo Thi My Nga

Keyword(s):

Mesoporous Silica ◽

Low Temperatures ◽

Mesoporous Material ◽

Bond Formation ◽

Step Method ◽

Chemical Methods ◽

Physico Chemical ◽

One Step ◽

The One ◽

Mcm 41

Di Linh bentonite was successfully pillared by mesoporous silica and this result had been published in previous reports. The acidity of this material was estimated by modern physico-chemical methods such as IR, TPD-NH3and the material was applied in the field of petrochemical catalysis. The acidity of the material has also been demonstrated by Cumen cracking at low temperatures about 350 °C with benzene conversion of 36.46 % and benzene selectivity of 73.98 %. In addition, the gasoline yield of silica mesoporous material pillared bentonite had got more twice higher than the one when using a mixture of bentonite powder and MCM-41 powder in the cracking Wax. This result confirms that the bond formation between bentonite and mesoporous silica when using one-step method, which increase acidity of the synthesized material.

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Transmission Electron Microscopy of Protein Macromolecules

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100066176 ◽

1971 ◽

Vol 29 ◽

pp. 424-425

Author(s):

Henry S. Slayter

Keyword(s):

Biological Systems ◽

Metal Vapor ◽

Resolving Power ◽

Electron Microscopic ◽

Chemical Methods ◽

Molecular Weights ◽

The Past ◽

Physical Chemical ◽

Transmission Electron

Electron microscopic methods have been applied increasingly during the past fifteen years, to problems in structural molecular biology. Used in conjunction with physical chemical methods and/or Fourier methods of analysis, they constitute powerful tools for determining sizes, shapes and modes of aggregation of biopolymers with molecular weights greater than 50, 000. However, the application of the e.m. to the determination of very fine structure approaching the limit of instrumental resolving power in biological systems has not been productive, due to various difficulties such as the destructive effects of dehydration, damage to the specimen by the electron beam, and lack of adequate and specific contrast. One of the most satisfactory methods for contrasting individual macromolecules involves the deposition of heavy metal vapor upon the specimen. We have investigated this process, and present here what we believe to be the more important considerations for optimizing it. Results of the application of these methods to several biological systems including muscle proteins, fibrinogen, ribosomes and chromatin will be discussed.

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Sem and X-Ray Analysis of Renal and Biliary Calculi

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100091512 ◽

1976 ◽

Vol 34 ◽

pp. 306-307

Author(s):

R. J. Narconis ◽

G. L. Johnson

Keyword(s):

Chemical Constituents ◽

Natural State ◽

X Ray Diffraction ◽

Chemical Methods ◽

X Ray ◽

Additional Dimension ◽

Biliary Calculi ◽

Calculus Formation ◽

Scanning Electron

Analysis of the constituents of renal and biliary calculi may be of help in the management of patients with calculous disease. Several methods of analysis are available for identifying these constituents. Most common are chemical methods, optical crystallography, x-ray diffraction, and infrared spectroscopy. The application of a SEM with x-ray analysis capabilities should be considered as an additional alternative.A scanning electron microscope equipped with an x-ray “mapping” attachment offers an additional dimension in its ability to locate elemental constituents geographically, and thus, provide a clue in determination of possible metabolic etiology in calculus formation. The ability of this method to give an undisturbed view of adjacent layers of elements in their natural state is of advantage in determining the sequence of formation of subsequent layers of chemical constituents.

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An Interactive Minicomputer Program for the Indexing and Simulation of Electron Diffraction Patterns

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100092670 ◽

1976 ◽

Vol 34 ◽

pp. 542-543

Author(s):

R.P. Goehner ◽

W.T. Hatfield ◽

Prakash Rao

Keyword(s):

Electron Diffraction ◽

Real Time ◽

Pattern Analysis ◽

Flow Diagram ◽

Hard Copy ◽

Time Analysis ◽

Real Time Analysis ◽

Transmission Electron ◽

One Step ◽

Diffraction Patterns

Computer programs are now available in various laboratories for the indexing and simulation of transmission electron diffraction patterns. Although these programs address themselves to the solution of various aspects of the indexing and simulation process, the ultimate goal is to perform real time diffraction pattern analysis directly off of the imaging screen of the transmission electron microscope. The program to be described in this paper represents one step prior to real time analysis. It involves the combination of two programs, described in an earlier paper(l), into a single program for use on an interactive basis with a minicomputer. In our case, the minicomputer is an INTERDATA 70 equipped with a Tektronix 4010-1 graphical display terminal and hard copy unit.A simplified flow diagram of the combined program, written in Fortran IV, is shown in Figure 1. It consists of two programs INDEX and TEDP which index and simulate electron diffraction patterns respectively. The user has the option of choosing either the indexing or simulating aspects of the combined program.

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Nutrient-regulated gene expression in eukaryotes

Biochemical Society Symposium ◽

10.1042/bss0730085 ◽

2006 ◽

Vol 73 ◽

pp. 85-96 ◽

Cited By ~ 8

Author(s):

Richard J. Reece ◽

Laila Beynon ◽

Stacey Holden ◽

Amanda D. Hughes ◽

Karine Rébora ◽

...

Keyword(s):

Gene Expression ◽

Rna Polymerase ◽

Rna Polymerase Ii ◽

Transcriptional Control ◽

Direct Interaction ◽

Signalling Pathways ◽

A Cell ◽

One Step ◽

Higher Eukaryotes ◽

Regulated Gene Expression

The recognition of changes in environmental conditions, and the ability to adapt to these changes, is essential for the viability of cells. There are numerous well characterized systems by which the presence or absence of an individual metabolite may be recognized by a cell. However, the recognition of a metabolite is just one step in a process that often results in changes in the expression of whole sets of genes required to respond to that metabolite. In higher eukaryotes, the signalling pathway between metabolite recognition and transcriptional control can be complex. Recent evidence from the relatively simple eukaryote yeast suggests that complex signalling pathways may be circumvented through the direct interaction between individual metabolites and regulators of RNA polymerase II-mediated transcription. Biochemical and structural analyses are beginning to unravel these elegant genetic control elements.

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