scholarly journals The Technique of Thyroid Cartilage Scaffold Support Formation for Extrusion-Based Bioprinting

2021 ◽  
Vol 7 (2) ◽  
Author(s):  
N. V. Arguchinskaya ◽  
E. E. Beketov ◽  
A. A Kisel ◽  
E. V. Isaeva ◽  
E. O. Osidak ◽  
...  
Keyword(s):  
Computed Tomography ◽  
3D Model ◽  
Thyroid Cartilage ◽  
Human Thyroid ◽  
Tissue Scaffold ◽  
Collagen Hydrogel ◽  
Temporary Support

During biofabrication, a tissue scaffold may require temporary support. The aim of this study was to develop an approach of human thyroid cartilage scaffold temporal support formation. The scaffold 3D-model was based on DICOM images. XY plane projections were used to form scaffold supporting part. To verify the technique, collagen hydrogel was chosen as the main scaffold component. Gelatin was applied for the supporting part. To test the applicability of the approach, a model of thyroid cartilage scaffold with the support was printed. The scaffold corresponded to a given model, although some discrepancy in geometry was observed during verification by computed tomography.

Androgen receptors and gender-specific distribution of alkaline phosphatase in human thyroid cartilage

2006 ◽  
Vol 126 (3) ◽  
pp. 381-388 ◽  
Author(s):  
Horst Claassen ◽  
Heiner Mönig ◽  
Saadettin Sel ◽  
Jochen A. Werner ◽  
Friedrich Paulsen
Keyword(s):  
Alkaline Phosphatase ◽  
Androgen Receptors ◽  
Thyroid Cartilage ◽  
Human Thyroid ◽  
Specific Distribution ◽  
And Gender ◽  
Gender Specific

Generation of a 3D model of the inside volume of shoes for e-commerce applications using industrial X-ray computed tomography

2021 ◽  
Author(s):  
J Wittmann ◽  
G Herl ◽  
J Hiller
Keyword(s):  
Computed Tomography ◽  
3D Model ◽  
Region Growing ◽  
Surface Model ◽  
Economic Potential ◽  
X Ray ◽  
Internet Users ◽  
Surface Data ◽  
X Ray Computed ◽  
The Individual

Abstract In 2018, 47 % of global internet users had purchased footwear products through the internet, making it the second most popular online shopping category worldwide right after clothing with 57 %. In the same year, on average, about every sixth parcel delivered in Germany (16.3 %) was returned. With the effort and costs that are associated with the return of shoes, the objective of reducing the number of returns for shoes promises an enormous economic potential and helps to reduce the CO2 emissions due to a lower trafic volume. This paper presents a workflow for determining the inside volume surface of shoes using industrial X-ray computed tomography (CT). The fundamental idea is based on the Region Growing (RG) method for the segmentation of the shoe's inner volume. Experiments are performed to illustrate the correlation of image quality and segmentation result. After obtaining the 3D surface model of an individual foot, the inner volume surface data of a scanned shoe can then be registered and evaluated in order to provide a reliable feedback for the customer regarding the accuracy of fit of a shoe and the individual foot on the basis of an overall "metric of comfort" before buying online. This step is not part of the work at hand. Conclusions are drawn and suggestions for improving the robustness and the exibility of the workflow are given, so it can be adapted to various shoe types and implemented in a fully automated measurement process in the future.

scholarly journals The use of 3D modeling to determine the parameters of surgical intervention for pulmonary tuberculosis

2020 ◽  
Vol 98 (6) ◽  
pp. 47-51
Author(s):  
E. A. Borodulinа ◽  
A. V. Kolsаnov ◽  
P. V. Rogozhkin ◽  
A. A. Mаnukyan
Keyword(s):  
Computed Tomography ◽  
Pulmonary Tuberculosis ◽  
3D Modeling ◽  
3D Model ◽  
Surgical Intervention ◽  
Bronchial Tree ◽  
Surgical Interventions ◽  
Color Mapping ◽  
Vascular Structures ◽  
Tomography Data

The clinical experience demonstrates the importance of 3D modeling when planning surgical intervention in patients with pulmonary tuberculosis. The 3D model was built up based computed tomography data using Avtoplan software with plug-ins for segmentation of the lung, pathological foci, vascular structures, and bronchial tree. The data obtained during 3D modeling allowed us to plan surgery and the data were fully confirmed during the operation. The 3D model with color mapping reveals syntopy, which is extremely difficult to determine using standard computed tomography and allows the wider use of minimally invasive endoscopic surgical interventions.

Ventral Cleft of the Larynx in an Adult

1989 ◽  
Vol 98 (1) ◽  
pp. 66-69 ◽  
Author(s):  
Joyce A. Schild ◽  
Mahmood F. Mafee
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Ct Scan ◽  
Thyroid Cartilage ◽  
Adult Form ◽  
Embryonic Period ◽  
Whole Mount

Congenital clefts of the larynx are rare and usually found dorsally. This case report describes a patient with a partial anterior nonfusion, or ventral cleft, of the thyroid cartilage. This was first noted on computed tomography of the larynx used for delineation of carcinoma and was confirmed by horizontal whole mount histologic sections of the resected larynx. The thyroid cartilage suggested arrested fusion of the laminae in the middle to late embryonic period. This patient had an adult form of this rarely reported anomaly and the first, to our knowledge, detected with CT scan.

scholarly journals Application of 3D Computed Tomography Reconstruction Images to Assess the Thickness and Dimensions of the Posterior Palatal Seal Area

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Soeun Lim ◽  
Seoung-Jin Hong ◽  
Joo-Young Ohe ◽  
Janghyun Paek
Keyword(s):  
Computed Tomography ◽  
3D Model ◽  
Three Dimensional ◽  
Ct Images ◽  
Anterior Border ◽  
Lateral Direction ◽  
Mean Dimension ◽  
The Mean ◽  
The Right ◽  
Palatal Mucosa

Few studies have been reported on the scientific measurements of the thickness and dimensions of the posterior palatal seal (PPS) area. The purpose of this study is to measure and analyze the thickness of palatal mucosa by using a three-dimensional (3D) model reconstructed with computed tomography (CT) images and to present objective values by identifying the PPS area. The CT images were reconstructed as a 3D model by separating the maxillary palate mucosa and teeth. Each reconstructed model was analyzed and the thickness was measured at 93 crossing points of each divided plane. The dimension of the PPS area was measured and the right and left dimensions of the PPS area were compared. The thickness of the palatal mucosa was thicker toward the posterior area. The thickness increased in the lateral direction and decreased again. In the PPS area, the mean dimension between the rearmost of anterior border and the most posterior line was 2.19 mm and the mean dimension between the forefront of anterior border and the most posterior line was 5.19 mm in the right side and 5.16 mm in the left side. The mean dimension from the center of the palate to the right most forward point was 6.85 mm, and the left was 7.36 mm. The new measurement method of palatal mucosal thickness is noninvasive, accurate, and easy to store and study, so it can be used effectively in planning and manufacturing the maxillary complete denture in the digital workflows.

Design of a Personalized Skin Grafting Methodology Using an Additive Biomanufacturing System Guided by 3D Photogrammetry

2015 ◽  
Author(s):  
Houzhu Ding ◽  
Filippos Tourlomousis ◽  
Azizbek Babakhanov ◽  
Robert C. Chang
Keyword(s):  
Skin Graft ◽  
3D Model ◽  
Digital Camera ◽  
Depth Map ◽  
Human Hand ◽  
Surface Model ◽  
Skin Area ◽  
Burn Wound ◽  
Tissue Scaffold ◽  
Artificial Hand

In this paper, the authors propose a novel method whereby a prescribed simulated skin graft is 3D printed, followed by the realization of a 3D model representation using an open-source software AutoDesk 123D Catch to reconstruct the entire simulated skin area. The methodology is photogrammetry, which measures the 3D model of a real-word object. Specifically, the principal algorithm of the photogrammetry is structure from motion (SfM) which provides a technique to reconstruct a 3D scene from a set of images collected using a digital camera. This is an efficient approach to reconstruct the burn depth compared to other non-intrusive 3D optical imaging modalities (laser scanning, optical coherence tomography). Initially, an artificial human hand with representative dimensions is designed using a CAD design program. Grooves with a step-like depth pattern are then incorporated into the design in order to simulate a skin burn wound depth map. Then, the *.stl format file of the virtually wounded artificial hand is extruded as a thermoplastic material, acrylonitrile butadiene styrene (ABS), using a commercial 3D printer. Next, images of the grooves representing different extents of burned injury are acquired by a digital camera from different directions with respect to the artificial hand. The images stored in a computer are then imported into AutoDesk 123D Catch to process the images, thereby yielding the 3D surface model of the simulated hand with a burn wound depth map. The output of the image processing is a 3D model file that represents the groove on the plastic object and thus the burned tissue area. One dimensional sliced sections of the designed model and reconstructed model are compared to evaluate the accuracy of the reconstruction methodology. Finally, the 3D CAD model is designed with a prescribed internal tissue scaffold structure and sent to the dedicated software of the 3D printing system to print the design of the virtual skin graft with biocompatible material poly-ε-caprolactone (PCL).

scholarly journals Three-dimensional visualisation of the internal anatomy of the sparrowhawk (Accipiter nisus) forelimb using contrast-enhanced micro-computed tomography

PeerJ ◽  
2017 ◽  
Vol 5 ◽  
pp. e3039 ◽  
Author(s):  
Fernanda Bribiesca-Contreras ◽  
William I. Sellers
Keyword(s):  
Computed Tomography ◽  
3D Model ◽  
Three Dimensional ◽  
Biomechanical Analysis ◽  
X Ray ◽  
Accipiter Nisus ◽  
Contrast Enhanced ◽  
Muscle Geometry ◽  
The Individual ◽  
Non Destructive

BackgroundGross dissection is a widespread method for studying animal anatomy, despite being highly destructive and time-consuming. X-ray computed tomography (CT) has been shown to be a non-destructive alternative for studying anatomical structures. However, in the past it has been limited to only being able to visualise mineralised tissues. In recent years, morphologists have started to use traditional X-ray contrast agents to allow the visualisation of soft tissue elements in the CT context. The aim of this project is to assess the ability of contrast-enhanced micro-CT (μCT) to construct a three-dimensional (3D) model of the musculoskeletal system of the bird wing and to quantify muscle geometry and any systematic changes due to shrinkage. We expect that this reconstruction can be used as an anatomical guide to the sparrowhawk wing musculature and form the basis of further biomechanical analysis of flight.MethodsA 3% iodine-buffered formalin solution with a 25-day staining period was used to visualise the wing myology of the sparrowhawk (Accipiter nisus). μCT scans of the wing were taken over the staining period until full penetration of the forelimb musculature by iodine was reached. A 3D model was reconstructed by manually segmenting out the individual elements of the avian wing using 3D visualisation software.ResultsDifferent patterns of contrast were observed over the duration of the staining treatment with the best results occurring after 25 days of staining. Staining made it possible to visualise and identify different elements of the soft tissue of the wing. Finally, a 3D reconstruction of the musculoskeletal system of the sparrowhawk wing is presented and numerical data of muscle geometry is compared to values obtained by dissection.DiscussionContrast-enhanced μCT allows the visualisation and identification of the wing myology of birds, including the smaller muscles in the hand, and provides a non-destructive way for quantifying muscle volume with an accuracy of 96.2%. By combining contrast-enhanced μCT with 3D visualisation techniques, it is possible to study the individual muscles of the forelimb in their original position and 3D design, which can be the basis of further biomechanical analysis. Because the stain can be washed out post analysis, this technique provides a means of obtaining quantitative muscle data from museum specimens non-destructively.

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