scholarly journals Evaluation of the antianginal effectiveness of trimetazidine in a new dosage form for a single dose, depending on the region of the Russian Federation. ODA trial results

Kardiologiia ◽  
2019 ◽  
Vol 59 (10S) ◽  
pp. 52-63 ◽  
Author(s):  
M. G. Glezer ◽  
V. A. Vygodin
Keyword(s):  
Risk Factors ◽  
Russian Federation ◽  
Dosage Form ◽  
North West ◽  
The Third ◽  
The North ◽  
Antianginal Effect ◽  
The Russian Federation ◽  
Artery Disease ◽  
North Western

The goal evaluation of the effectiveness of treatment with the new TMZ OD dosage form in different regions of the Russian Federation and regional differences in the clinical characteristics of patients with coronary artery disease included in the observation, the nature of their therapy, the presence and degree of correction of modifiable risk factors in real clinical practice. Material. Used database research ODA (Evaluation of the effectiveness and therapeutic response to Preductal OD 80 mg in everyday practical use for the treatment of stable angina), which was conducted in 56 cities of the Russian Federation. The analysis was carried out in the Central, North-West, Volga districts and regions united by the territorial principle – Southern + North Caucasian + Crimea + Sevastopol and Ural + Siberian + Far Eastern. Results. By region, there were no differences in the ratio of men and women included in the observation, the number of smoking patients (about 15%), overweight (about 80% of patients), arterial hypertension (exceeding 85%),dyslipidemia (over 90%), and atrial fibrillation (met at each 8-10 included patient). The proportion of patients older than 65 years was greater in the Central, North-West and Ural regions. Unfavorable heredity in coronary artery disease is more common in the Southern, Central and Ural regions. More than 2/3 of the patients had low physical activity, and in the South — their number reached ¾ of all included in the observation. The largest number of patients with diabetes was in the Central and North-West regions (every fourth patient), in the Ural region every fifth. The lowest frequency of statin prescribing was in the Volga region. The smallest number of those receiving RAS inhibitors was in the North-West, Ural and South regions. Beta blockers took more than 80% of patients. Only 35% of patients had a target systolic blood pressure. The smallest proportion of people with target blood pressure values was in the NorthWest and South regions. Adding TMZ OD to therapy or replacing previous therapy with trimetazidine on TMZ OD in all regions resulted in a significant (p <0.001) decrease in the incidence of angina attacks by as early as 1 month of therapy and the antianginal effect increased by the third month of treatment. By the third month of treatment, the average frequency of angina attacks was the lowest in the North-Western and Ural regions (significantly lower than even in the Central region) and remained higher only in the Volga region compared to the Central, North-Western and Ural regions. During follow-up, treatment compliance increased significantly in all regions. Conclusion. The fight against major risk factors remains insufficient and efforts should be made to change the situation in all regions of the Russian Federation. The inclusion of trimetazidine in therapy in the new TMZ OD dosage form allows to obtain a pronounced antianginal effect and increase adherence to therapy. Low adherence can be overcome by careful observation and closer contact between doctors and patients.

scholarly journals Some aspects of the navigation period extension in the North-West Basin of inland waterways of the Russian Federation

2021 ◽  
Vol 258 ◽  
pp. 02004
Author(s):  
Vladimir Karetnikov ◽  
Vyacheslav Bekriashev ◽  
Gleb Chistiakov ◽  
Sergey Rudiyh
Keyword(s):  
Russian Federation ◽  
Western Region ◽  
Inland Waterways ◽  
North West ◽  
The North ◽  
Winter Conditions ◽  
Lena Basin ◽  
The Russian Federation ◽  
West Basin ◽  
North Western

The Russian Federation has a developed system of inland waterways (IWW) [1]. This system consists of 15 basins. Winter conditions are very harsh in some basins. Such basins, for example, include the Lena Basin. But in some basins, even in winter, conditions that block navigation do not form. These basins include the Volga-Baltic. However, during the extension of the navigation period in such basins, it should be borne in mind that the navigation safety system will have to be upgraded. This paper discusses some aspects, the introduction of which forms the prerequisites for extension of the navigation period on the waterways of the North-Western region of the Russian Federation. In addition, specific recommendations are provided for the implementation of the necessary automated systems to ensure a sufficient level of navigation in winter conditions on the IWW. These recommendations were obtained within the framework of the international project INFUTURE.

scholarly journals Cultivation of fireweed (Epilobium ngustifolium) together with nettle dioecious (Urtica dioica)

2020 ◽  
Vol 176 ◽  
pp. 03004
Author(s):  
Boris Starkovskiy ◽  
Gennadiy Simonov ◽  
Yulia Malinovskaya
Keyword(s):  
Russian Federation ◽  
Single Species ◽  
Urtica Dioica ◽  
Metabolizable Energy ◽  
Western Region ◽  
The Third ◽  
The North ◽  
The Russian Federation ◽  
North Western

The authors studied the possibility of cultivating fireweed in a grass mixture with nettle dioecious in the conditions of the North-Western region of the Russian Federation. It has been stated that both plants begin to grow immediately after snowmelt. The blooming phase of nettle begins simultaneously with that of fireweed. As the plants grow and develop in a grass mixture, the suppression of fireweed is noted. In the third year of life, nettle stalks were higher than those of fireweed. During the period of research, the productivity of the grass mixture was lower than that of pure fireweed plantings by 1.3 t/ha. In the single-species option, the amount of protein and the amount of metabolizable energy were 348 kg/ha and 19.5 GJ/ha respectively, which is 42 kg/ha and 2.5 GJ/ha higher than in the grass mixture. Nettle dioecious forms dense bushes in the third year of growing. Fireweed turns out to be in unfavorable conditions: its growing energy decreases, it comes into the blooming phase earlier and its suppression from the coenosis by nettle becomes evident.

Экологическое испытание гибрида огурца F1 Энеж 21 в открытом грунте

2018 ◽  
Author(s):  
L.A. Chistyakova ◽  
O.V. Baklanova ◽  
E.L. Makarova ◽  
Yu.V. Bortsova
Keyword(s):  
Russian Federation ◽  
High Potential ◽  
Moscow Region ◽  
North West ◽  
The North ◽  
Pickling Cucumber ◽  
West Central ◽  
Open Ground ◽  
Chuvash Republic ◽  
The Russian Federation

Приведены результаты испытания нового перспективного партенокарпического гибрида огурца корнишонного типа F1 Энеж 21, созданного селекционерами агрохолдинга «Поиск», в условиях открытого грунта в Северо-Западном, Центральном и Волго-Вятском регионах Российской Федерации: Костромская, Ярославская, Московская, Рязанская, Тульская область и Чувашская Республика. Высокие потенциальные возможности и адаптационные свойства гибрида F1 Энеж 21 наиболее значимо проявляются в Московской области (63,8 т/га), Чувашской Республике (39,4 т/га) и Рязанской области (31,2 т/га).The article presents the results of testing a new promising parthenocarpic pickling cucumber hybrid F1 Enezh 21, selected by the breedrs of the Agricultural holding «Poisk» in conditions of open ground in the North-West, Central and Volga-Vyatka regions of the Russian Federation: Kostroma, Yaroslavl, Moscow, Ryazan, Tula regions and the Chuvash Republic. The high potential and adaptation characteristic of the F1 Enezh 21 hybrid are most significantly presented in condition of the Moscow region (63.8 t / ha), the Chuvash Republic (39.4 t / ha) and the Ryazan region (31.2 t / ha).

ОЦЕНКА ПЕРСПЕКТИВ ПОЛИТИЧЕСКОГО БУДУЩЕГО РОССИЙСКОЙ МОЛОДЕЖЬЮ

2020 ◽  
Vol 14 (4) ◽  
pp. 28
Author(s):  
O. V. Lagutin ◽  
E. O. Negrov
Keyword(s):  
Russian Federation ◽  
Political Process ◽  
The Political ◽  
Youth Organizations ◽  
Significant Group ◽  
North West ◽  
Youth Leaders ◽  
The North ◽  
Rfbr Grant ◽  
The Russian Federation

The article deals with the assessment of the prospects of the political future by representatives of Russian youth. The text of the article has been prepared within the framework of the project “Potential of Youth Political Leadership in The Course of Political Socialization and Circulation of Elites in the Russia Regions in the 2010s (using the example of South-Western Siberia and the North-West of the Russian Federation), RFBR grant No. 18-011-01184. The relevance of the research is in combining a fundamental review of the main directions of research of the role of youth participation in the social and political process and the involvement of a specific empirical study conducted in the spring of 2019, which allows highlighting various aspects of the situation. The empirical part of the study is based on the study “Ideas of Youth about Possibilities of Youth Leaders and Youth Organizations in Russia”, which was conducted in spring 2019 in four constituent entities of the Russian Federation — Altai Territory, Leningrad and Novosibirsk Regions and St. Petersburg. The method of research was a personal standardized interview, the sample size was 1000 respondents (250 in each of the regions), representatives of young people aged 14 to 30 permanently reside in the territory of the studied subjects of the federation. Based on factor and cluster analyzes, the main models of expectations of the political future are presented. The article should be of interest to researchers, both professionally involved, and simply interested in the topic of the influence of the real political process on such a significant group of the population as youth.

MORBIDITY, MORTALITY AND RELIABILITY OF ACCOUNTING OF PATIENTS OF DIFFERENT AGE GROUPS WITH LIVER CANCER IN RUSSIA

2020 ◽  
pp. 240-245
Author(s):  
В. М. Мерабишвили ◽  
В. К. Гуркало ◽  
Э. Н. Мерабишвили
Keyword(s):  
Liver Cancer ◽  
Russian Federation ◽  
Malignant Tumors ◽  
Primary Liver Cancer ◽  
Age Groups ◽  
Federal District ◽  
Cancer Register ◽  
The North ◽  
The Russian Federation ◽  
North Western

Рак печени (РП) - тяжелейшая онкопатология. В России смертность превышает число первично-учтенных больных в среднем. Ежегодно в России регистрируют более 8 тыс. (8 810 - в 2018 г.) случаев рака печени и более 10 тыс. (10 018 - в 2018 г.) случаев смерти от этой причины. Использованы стандартные методы медицинской статистики, все зарегистрированные первичные случаи РП в России. Углубленная разработка материала проведена на основе базы данных Популяционного ракового регистра Северо-Западного Федерального округа РФ. Проанализированы данные всего комплекса доступной информации в целом по России. Установлен прирост заболеваемости РП населения России за 18 лет в «грубых» показателях и абсолютных числах на 20% и в стандартизованных - на 1,22%. У женщин отмечено снижение учтенных случаев РП на 4,55%. Смертность населения России в стандартизованных показателях снизилась за 18 лет практически на 3%. Превышение числа умерших над заболевшими от РП существенно возрастает в старших возрастных группах. Индекс достоверности учета (ИДУ) - это отношение абсолютных чисел или «грубых» показателей смертности населения к заболеваемости. Для всех злокачественных новообразований (ЗНО) величина в среднем по России составила 0,47, практически совпадающая со среднеевропейской. ИДУ у мужчин - 0,55, выше расчетных показателей для женщин - 0,40, что в первую очередь связано с более благоприятной структурой заболеваемости женщин ЗНО. Медиана выживаемости первичных больных РП составляет немногим более 3 мес. Пятилетняя выживаемость больных РП даже на ранних стадиях составляет у лиц моложе 60 лет с I стадией - 25,3%, старше 60 лет - только 17,2%, со II стадией - 17,9 и 11% соответственно. Liver cancer is a severe oncopathology. Mortality exceeds the number of primary-accounted patients in Russia on average. Every year in Russia more than eight thousand (8 810 in 2018) cases of liver cancer and more than 10 000 (10 018 in 2018) deaths from this cause are registered. Used Standard methods of medical statistics, all registered primary cases of liver cancer in Russia. In-depth development of the material was carried out on the basis of the database of the Population cancer register of the North-Western Federal district of the Russian Federation. The analysis of the data of the whole complex of available information in Russia as a whole is carried out. In-depth data development was carried out on the basis of the database of the Population cancer register of the North-Western Federal district of the Russian Federation. The increase in the incidence of liver cancer in Russia over 18 years in «rough» indicators and absolute numbers by 20 % and in standardized by 1,22 % was established. In women, there was a decrease in reported cases of liver cancer by 4,55 %. The mortality rate of the Russian population in standardized indicators has decreased by almost 3 % over 18 years. The excess of the number of deaths over those from liver cancer increases significantly in older age groups. The index of reliability of accounting is the ratio of absolute numbers or «rough» indicators of mortality to morbidity. For all malignant tumors, its value on average in Russia was 0,47, almost coinciding with the average European. The index of reliability of accounting for men is 0,55, higher than the calculated indicators for women - 0,40, which is primarily due to a more favorable structure of the incidence of malignant tumors in women. The median survival of primary liver cancer patients is a little more than three months. The fi ve-year survival rate of patients with liver cancer even in the early stages is in the first among persons younger than 60 years - 25,3 %, over 60 years - only 17,2 %, in the second, respectively, 17,9 and 11%.

The Dialectical Position of the Niya Prakrit

1936 ◽  
Vol 8 (2-3) ◽  
pp. 419-435 ◽  
Author(s):  
T. Burrow
Keyword(s):  
Third Century ◽  
North West ◽  
Modern Times ◽  
The Third ◽  
The North ◽  
Characteristic Features ◽  
North Western

The “North-Western Prakrit” as Konow has called it is represented by the following documents.(1) The two versions of Aśoka's edicts preserved at Mansehra’ and Shahbazgarhi. At this stage many of the characteristic features of the language have not yet developed, e.g. śr > ṣ, śv > śp.(2) The later Kharoṣṭhi inscriptions, mostly short, collected by Konow in the second volume of the Corp. Inscr. Ind.(3) The Kharoṣṭhi manuscript of the Dhammapada discovered near Khotan (Manuscript Dutreuil du Rhins).(4) The Kharoṣṭhi documents from Niya, representing the administrative language of the Shan-Shan kingdom in the third century A.D. In the Journ. As., 1912, pp. 337 ff., J. Bloch examined the dialectical peculiarities of the Manuscript Dutreuil du Rhins and showed that they appeared in modern times in the languages of the North-West.

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