scholarly journals Drug utilization study in ischaemic heart disease in a tertiary care hospital, Mangalore, India

2017 ◽  
Vol 6 (7) ◽  
pp. 1799 ◽  
Author(s):  
Tittu George Zachariah ◽  
Subramanyam K. ◽  
Pooja M. ◽  
Vinayak J. Kempaller
Keyword(s):  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Drug Utilization ◽  
Drug Prescription ◽  
Tertiary Care ◽  
New Drugs ◽  
Prescription Data ◽  
Care Hospital ◽  
Number Of Patients ◽  
One Year

Background: The study of drug utilization is a component of a medical audit and periodic evaluation need to be done to enable suitable modifications in prescription of drugs to increase the therapeutic benefit and decrease the adverse effects. When new drugs are used additional information on safety and efficacy may be generated. Ischaemic heart disease (IHD) is a condition in which there is an inadequate supply of blood and oxygen to a portion of the myocardium. Medications for IHD include anti-platelet therapy, nitrates, statins, ACE inhibitors, beta blockers, CCB’s, diuretics.Methods: The study was carried out at cardiology department of K. S. Hegde Charitable Hospital for a period of one year from January 2015, and relevant retrospective data were also collected from hospital records for period pertaining to one year from 1/1/2013.Results: We assessed discharge summaries of 950 patients and found that majority of patients were males than females. The highest number of patients were in the age group of 51-60 years. Polypharmacy has been observed in our study. The average number of days spent by the patients in the hospital was 3.5 days. None of the drugs were prescribed using generic names, all the drugs (100%) were prescribed in brand names only. Common co-morbidities associated with IHD were hypertension and diabetes. Most commonly prescribed drugs for IHD were Aspirin, followed by Atorvastatin, Clopidogrel, and Nitrates.Conclusions: In our study, on analysing the drug prescription data it was observed that there was no statistically significant change in drug utilization between the two years.

scholarly journals DRUG UTILIZATION STUDY IN OPHTHALMOLOGY OUTPATIENT DEPARTMENT IN A GOVERNMENT TERTIARY CARE HOSPITAL IN MAHARASHTRA

2018 ◽  
Vol 11 (7) ◽  
pp. 167
Author(s):  
Nishandar Tb ◽  
Kale As ◽  
Pise Hn ◽  
Jambhrunkar Sd
Keyword(s):  
Drug Utilization ◽  
Drug Exposure ◽  
Tertiary Care Hospital ◽  
Drug Prescription ◽  
Tertiary Care ◽  
Outpatient Department ◽  
Essential Medicines ◽  
World Health ◽  
Care Hospital ◽  
Age Group

Objective: Drug utilization research is an essential part of pharmacoepidemiology as it describes the extent, nature, and determinants of drug exposure. Indiscriminate use of topical antibiotics, steroids, and nonsteroidal anti-inflammatory drugs causes histological and structural changes in the conjunctiva. The present study was proposed to investigate prescription and drug utilization practices in ophthalmology outpatient department (OPD) in a government tertiary care hospital in Maharashtra.Methodology: An observational, cross-sectional study was conducted in a tertiary care teaching hospital of rural Maharashtra, India, from January 2015 to June 2016 after approval of the institutional ethics committee. Patients of all age group and of either gender attending ophthalmology OPD in a tertiary care hospital were included in the study. Patients not willing to consent as well as follow-up patients were excluded from the study. Data collection was done in a predesigned pro forma. Prescriptions were evaluated for demographic data, World Health Organization (WHO) core drug prescription indicators. Statistical analysis was performed using Microsoft Office Excel® 2007.Results: In a total of 600 patients, females outnumbered males. A bit less than a half of patients belonged to the age group of 19–45 years. An average number of drugs per encounter was (1080/600), i.e. 1.8. Of 1080 total drugs prescribed, 678 drugs (62.78%) were prescribed by their generic name. 1027/1080 (95.09%) drugs were prescribed from the National List of Essential Medicines and 671/1080 (62.13%) drugs prescribed were from the WHO- Essential medicines List. Total encounters having antibiotics and injectable formulations were 274 (45.66%) and 4 (0.66%), respectively.Discussion: Drug utilization studies (DUS) are a tool for assessing the prescribing, dispensing, and distribution of drugs. The main aim of DUS is to facilitate rational use of medicines. Overall findings of the study suggest that ophthalmologists’ drug prescribing habits were appropriate to a larger extent in the current setting.

scholarly journals An audit of indoor morbidity and mortality in a medical ward at a Tertiary Care Hospital

2016 ◽  
Vol 11 (1) ◽  
Author(s):  
Abeer Qadir ◽  
Muhammad Arif Nadeem ◽  
Atif Munir ◽  
Zafar Ullah Khan
Keyword(s):  
Heart Disease ◽  
Liver Disease ◽  
Ischemic Heart Disease ◽  
Chronic Liver Disease ◽  
Tertiary Care ◽  
Chronic Liver ◽  
Ischemic Heart ◽  
Care Hospital ◽  
Cerebrovascular Accidents ◽  
Number Of Patients

There is a great geographical variation in disease burden around the world, which is due primarily to environmental, genetic, social and economic factors. Similar variations exist in worldwide mortality figures from a particular disease that can be attributed almost entirely to the access and efficacy of healthcare facilities. We did this audit to identify the major causes of morbidity and mortality in patients admitted in a medical unit of a tertiary care hospital and to highlight the importance of primary prevention. The audit was carried out in West Medical Ward Mayo Hospital Lahore, Pakistan from 1st January 2004 to 31st December 2004. All patients admitted with medical problems from the Outpatient and Emergency Departments were included. During the year 2004, a total of 2045 patients were admitted, out of which maximum number of patients admitted in the ward were suffering from chronic liver disease (17%) followed by ischemic heart disease (14.4%) cerebrovascular accidents (10.4%) and renal diseases. Total number of deaths were 321 with male mortality was 167 (14.40%) and female mortality 154 (17.40%). Chronic liver disease also had the highest mortality (16.8%) followed by cerebrovascular accidents (14%), renal disease (11.5%) and ischemic heart disease (7.8%). Even the mortality due to chronic liver disease was significantly higher (p <0.01) than ischernic heart disease. The number of patients having the four common diseases having age 45 years or more (770) was significantly greater (p <0.0001) then the number of patients (279) in the age range of 15 to 44 years. It was observed that significantly greater number of male patients (595) had morbidity than females (462), (p <0.0001), while mortality has no difference. Chronic liver disease, ischemic heart disease and cerebrovascular accidents are the diseases putting maximum burden on our health resources and disabling our productive population. This audit highlights the fact that all these three groups of diseases can be prevented and thus obviates the need of primary prevention of these major killers.

scholarly journals Analysis of factors responsible for intrauterine fetal death in rural pregnant women at tertiary care centre of Northern India

2017 ◽  
Vol 6 (9) ◽  
pp. 4071 ◽  
Author(s):  
Shaveta Garg ◽  
Naina Kumar
Keyword(s):  
Fetal Death ◽  
Tertiary Care ◽  
Intrauterine Fetal Death ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Northern India ◽  
Number Of Patients ◽  
Tragic Event ◽  
Abruptio Placenta ◽  
One Year

Background: Intrauterine fetal death (IUFD) is a tragic event for both the parents and obstetrician. Objectives of current study were to study the underlying etiology of Intra Uterine Fetal Death (IUFD) that can be helpful in formulating the preventive measures.Methods: This study was conducted over a period of one year from April 2016 till March 2017 at a tertiary rural care hospital. All patients with diagnosed IUFD at >24 weeks of gestation were included in the study.Results: Total eighty patients were admitted with diagnosis of intrauterine fetal death. Among these majority 58 (72.5%) were multigravida and only 22 (27.5%) were primigravida. Maximum number of patients, 61 (72.5%) were between age group of 20-30 years. Maximum number of IUFD were reported between 36-40 weeks of gestation (36.25%). Most of fetal deaths were due to preventable conditions like hypertensive disorders of pregnancy (28.75%), severe anemia (15%), abruptio placenta (11.25%), and rupture uterus (10%). Out of these patients 68 (85%) delivered vaginally and 7 patients were delivered by LSCS.Conclusions: The present study emphasizes the role of health education, regular antenatal checkups, early detection of complications and hospital delivery to reduce the overall preventable IUFD.

scholarly journals PROPORTION OF POSITIVE STRESS TEST IN YOUNGER PATIENTS COMING TO TERTIARY CARE HOSPITAL FOR THE EVALUATION OF ISCHAEMIC HEART DISEASE. ARE WE GOING TO LOSE OUR YOUNGER WORKFORCE?

2020 ◽  
Vol 53 (1) ◽  
Author(s):  
Muhammad Tariq Farman ◽  
Nauman Matloob Ahmed Siddiqui ◽  
Khalid Iqbal Bhatti ◽  
Muhammad Uzair Khan ◽  
Faisal Ahmed Siddiqui ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Tertiary Care Hospital ◽  
Stress Test ◽  
Tertiary Care ◽  
Care Hospital ◽  
Younger Patients

scholarly journals DRUG UTILIZATION PATTERN FOR SKIN DISEASES IN DERMATOLOGY OPD AT TERTIARY CARE HOSPITAL OF WESTERN MAHARASHTRA

2019 ◽  
pp. 20-23
Author(s):  
Kiran P Vakade ◽  
Vishal A Indurkar ◽  
Aayush H Chordia
Keyword(s):  
Drug Utilization ◽  
Skin Diseases ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Age Group ◽  
Skin Disorders ◽  
Utilization Pattern ◽  
Cost Effective Treatment ◽  
Number Of Patients

Background: Periodic auditing of prescriptions in terms of drug utilization study is an important tool to enhance the efficacy of the treatment, to decrease the risk of the adverse effects, to give cost-effective treatment and to provide useful feedback to the clinician. Prevalence of dermatological diseases is very high throughout the world, and in day to day practice, a quarter of the cases are related to dermatological manifestations. In studies conducted in the Out Patient  Department (OPD) of dermatology in North Palestine and Western Nepal, irrationalities in the prescriptions have been reported. Aim: To study the drug utilization pattern for skin diseases in dermatology OPD at tertiary care hospital of Western Maharashtra. Methodology: The retrospective analysis of dermatology OPD records of 6 months (1st March 2018- 31st August 2018) was carried out during the study period (1st September 2018 to 30th November 2018). The proforma for collecting data was designed. Demographic details, diagnosis and treatment are given for each patient were recorded. The data collected was condensed, and the master chart was prepared for data analysis. Result: During the study period, a total of 3869 patient’s case records were studied and analysed. A maximum number of patients (26.5%) found in the age group 31-40 years, followed by 23.5% of patients in the age group 21- 30 years. Fungal infection was found in 39.6 % of patients followed by acne in 14.2% patients and eczema in 9.1% of patients. Drugs most commonly prescribed were antihistaminics (45.02%) followed by antifungal (39.6%) and steroids (27.8%). Levocetirizine (74.07%) and hydroxyzine (16.5%) were the most commonly prescribed antihistaminics. Itraconazole (58.17%) and Griseofulvin (24.67%) were the most commonly used oral antifungal drugs. Miconazole (73.73%) was the most commonly used topical antifungal drug, followed by ketoconazole (12.45%). Among steroids, prednisone (52%) and betamethasone (38.05%) were the most commonly used steroids by oral route while clobetasol (68.09%) and mometasone (19.5%) were the most commonly used steroids by topical route. Our study revealed that the percentage of drugs prescribed by the WHO essential drug list was only 23.87%. Drugs which prescribed by the generic names were less than <1%. Conclusion: Treatment protocols used in the management of skin disorders were near to the standard guidelines.  Keywords: Drug utilization; Prescription pattern; Dermatology; Skin disorders.

scholarly journals DRUG UTILIZATION PATTERN IN GERIATRIC PATIENTS ATTENDING OUT PATIENT DEPARTMENT AT RURAL TERTIARY CARE HOSPITAL IN MAHARASHTRA.

2017 ◽  
Vol 10 (2) ◽  
pp. 314
Author(s):  
Tushar B Nishandar ◽  
Anand S Kale ◽  
Harshal N Pise
Keyword(s):  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Drug Prescription ◽  
Demographic Data ◽  
Tertiary Care ◽  
Outpatient Department ◽  
Essential Medicines ◽  
Care Hospital ◽  
Drug Prescribing ◽  
Prescription Pattern

Objective: To observe a prescription pattern in elderly patients attending outpatient department (OPD) and evaluating prescriptions according to theWorld Health Organization (WHO) prescription indicators.Methods: A cross-sectional observational study was conducted from July to September 2015. Patients of either gender, age 60 years or more, attending OPD in tertiary care hospital were included in the study. Prescriptions of medical practitioners were collected and evaluated for demographic data and the WHO drug prescribing indicators.Results: A total of 600 patients were enrolled in the study. The majority of the patients were in the age group 60-69 years (66.33%) with male preponderance (61%). The average number of drugs per prescription was 3.41. Out of 2045 drugs prescribed, 1261 drugs (61.66%) were prescribed by their generic name and 784 drugs (38.33%) were prescribed by their brand name. 1700 drugs (83.12%) prescribed were from the WHOs essential medicines list 2015. Total encounters involving injectable usage were 0.15%. Drugs acting on the cardiovascular system (21.12%) were the most frequently prescribed, followed by nonsteroidal anti-inflammatory drugs (NSAIDs) (20%). Ranitidine (16.62%) is the most frequently prescribed drug. Conclusions: In this study, drug prescription pattern was rational as per the WHO drug prescribing indicators. However, issues such as polypharmacy and inaccuracies of dose and duration were seen.Keywords: Drug utilization study, Geriatric, Outpatient department, Rational use of medicines.

DRUG UTILIZATION PATTERN AND RISK ELEMENTS OF STROKE PATIENTS IN A TERTIARY CARE HOSPITAL: A CROSS SECTIONAL STUDY.

2021 ◽  
pp. 20-23
Author(s):  
Giridhar Dasegowda ◽  
Girish M Bengalorkar ◽  
Salma Sadaf ◽  
Priyanka Prasanna Kumar Belaguthi ◽  
Sanjiti Mirmire ◽  
...  
Keyword(s):  
Risk Factors ◽  
Drug Utilization ◽  
Drug Prescription ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Health Concern ◽  
Care Hospital ◽  
Sectional Study ◽  
Utilization Pattern ◽  
Cross Sectional

Background: Stroke is not only one of the leading causes of morbidity and mortality worldwide but is also a topic of major public health concern in developing countries with a prevalence of 44 - 559 per 100,000 people. This study focuses on risk factors, socioeconomic distribution, drug utilization pattern, rehabilitation of patients and possible solutions to the encountered problems. Methods: Patients admitted to ESIC MC & PGIMSR, Bangalore were included in this cross-sectional study. A complete prole of patients diagnosed with stroke was obtained. On analysing the data obtained from 51 patients Results: under study, it was noted that ischemic stroke was the highest (84.31%), and stroke in males (70.59%) was higher than among females (29.41%) with highest occurrences between 55-70 years of age (41.18%). A large number of people were found to have >=3 risk factors (72.54%), including hypertension (78.43%), alcoholism (50.98%), diabetes mellitus (49.02%), smoking (47.05%), and dyslipidemia (27.45%). It was found that an average patient is prescribed 3.01 drugs in generic name and 4.68 in brand name (p<0.05). The study also highlighted the inadequacy of physiotherapy (39.21%), speech-therapy (11.76%) and occupational-therapy (0%). An understanding of risk factors and drug prescription strategies fol Conclusion: lowed by physicians across different socioeconomic groups helps to ne tune management strategies in accordance with guidelines, to provide a better quality of life to patients.

scholarly journals Study of drug prescription pattern among COPD patients admitted to medicine in-patient department of tertiary care hospital

2017 ◽  
Vol 6 (9) ◽  
pp. 2228
Author(s):  
Mahadeo P. Sawant ◽  
Sudhir L. Padwal ◽  
Anand S. Kale ◽  
Harshal N. Pise ◽  
Rucha M. Shinde
Keyword(s):  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Drug Prescription ◽  
Tertiary Care ◽  
Study Data ◽  
Brand Names ◽  
Care Hospital ◽  
Hospital Data ◽  
Copd Patients ◽  
Drug Utilization Studies

Background: Drug utilization studies can provide insights into a pattern, quality, determinants and outcomes of drug use. COPD is one of the leading causes of death among Indian population and there is a lack of drug utilization studies in this field.Methods: A prospective, observational study was conducted among the patients admitted in inpatient department of medicine ward of Tertiary care hospital. Data has collected from COPD patients admission records. Parameters like demographic profile, common associated diseases, WHO core drug indicators and commonly prescribed drugs were assessed from the prescriptions.Results: A total 284 inpatient records were scrutinized. Out of 284 patients, 66.19% were male and 33.80% were female. Average numbers of drugs per prescription were 7. Mean age was 66.9 years. Antimicrobials (88.7%) were most commonly prescribed drugs followed by inhaled bronchodilators (84.5%).Conclusions: Study data highlights that average numbers of drugs prescribed were higher than WHO norms, antibiotics were commonly used, and drugs prescribed with brand names were higher than the generic names.

scholarly journals Adverse drug reactions monitoring of newer oral hypoglycemic drugs in a tertiary care hospital of North India: a prospective study

2017 ◽  
Vol 6 (10) ◽  
pp. 2434
Author(s):  
Shephali Singh ◽  
Nilam Nigam ◽  
Shalini Gupta ◽  
Shravan Kumar
Keyword(s):  
Adverse Drug Reactions ◽  
Tertiary Care ◽  
New Drugs ◽  
North India ◽  
Care Hospital ◽  
Drug Reactions ◽  
Dpp Iv ◽  
Number Of Patients ◽  
Oral Hypoglycemics ◽  
Oral Hypoglycemic Drugs

Background: Diabetes Mellitus (DM) is a metabolic disorder characterized by hyperglycemia. In majority of patients oral hypoglycemic drugs remain the primary agents in management of DM. Currently there are variety of new drugs are approved in management of DM of which safety is established in clinical trials but there surveillance is needed for reporting newer adverse effects which are not documented yet.Methods: 112 patients were screened with the help of a predefined inclusion and exclusion criteria for the study and followed up for three months. The drugs which are relatively new and have been in the market for around 5-7 years were taken as new drug. These include specifically the following drugs: DPP-IV Inhibitors, PPAR α/γ agonist, SGLT-2 inhibitors. They were screened and investigated suitably for any ADRs. The severity of the adverse drug reactions was graded according to the Hartwig’s Severity Assessment Scale and Naranjo Scale was used for causality assessment between the drug and suspected reaction.Results: Maximum ADRs reported belonged to gastro intestinal system (53%). DPP-IV inhibitors showed maximum number of ADRs i.e. 70.6%. Majority of ADRs reported were mild i.e. 52.9%. Overall 15.2% patients reported ADRs. Majority of ADRs reported (70.6%) belonged to category ‘possible’.Conclusions: All three class of newer oral hypoglycemics seems reasonably safe to be used in general practice. As the number of patients were small, we need larger study to substantiate the findings.

scholarly journals Study of drug prescription pattern in ischemic heart disease patients

2019 ◽  
Vol 8 (7) ◽  
pp. 1473
Author(s):  
Mahadeo P. Sawant ◽  
Sudhir L. Padwal ◽  
Rakesh R. Jadhav ◽  
Harshal N. Pise ◽  
Rucha Shinde
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Drug Utilization ◽  
Drug Prescription ◽  
Tertiary Care ◽  
Ischemic Heart ◽  
Essential Medicines ◽  
Utilization Pattern ◽  
Prescribing Pattern ◽  
Cross Sectional

Background: Drug utilization pattern studies helps to screen, assess and propose appropriate modifications in prescription practices, this would help to make patient care rational and cost effective. Study was intended to analyse the drug prescribing pattern for treatment of Ischemic heart disease using WHO indicators.Methods: This is a cross sectional observational study conducted on ischemic heart disease patients admitted at inpatient department of medicine in a tertiary care teaching hospital. The study consisted of analysis of drug utilization pattern of prescribed drugs.Results: IHD was more commonly seen in males (70.06%) than females (29.94%). IHD was most commonly seen in patients of age group of 61-70 year. Drugs prescribed to patients belong to various therapeutic classes ranging from anti-platelets, anticoagulants, anti-anginal, antithrombin, thrombolytic, hypolipidemics. The most commonly prescribed therapeutic class of drugs was antiplatelet (86.26%) followed by hypolipidemic (82.25%) and ACE inhibitors drugs (46.60%). Average number of drugs per encounter was 7.70. Drugs were prescribed by their generic names were 29.99%. Out of total study group 22.06% patients were prescribed at least one antibiotic. Injections were prescribed only in 1392 (27.86%) out of 4995 drugs. Of total drugs 3270 (65.45%) of drugs were from National List of Essential Medicines-2016 (NLEM -2016) and 2774 (55.53%) drugs prescribed were from WHO-EML-2016.Conclusions: Risk of artery disease increased with increasing age. IHD was more common in males than females. The most commonly prescribed drug classes in Ischemic heart disease were anti-platelet drugs followed by hypolipidemic agents.

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