scholarly journals A one year case control study on oxytocin use in labor and its effect on maternal: fetal outcomes

2018 ◽  
Vol 7 (3) ◽  
pp. 391
Author(s):  
Devendra Singh Kushwah ◽  
Beenu Kushwah
Keyword(s):  
Health Professionals ◽  
Analytical Study ◽  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
Medical College ◽  
Study Population ◽  
Oxytocin Augmentation ◽  
One Year ◽  
Control Study

Background: Oxytocin is a drug commonly administered drug to a pregnant lady during labor, nowadays even without an indication, in the hope that the progress of labor can be improved and the need for cesarean delivery may be reduced. This study emphasizes the need for using safeguards like use of checklists before starting oxytocin augmentation, therefore ensuring its rational use to minimize maternal and neonatal complications when augmenting labor with oxytocin, including rigorous indications, use of minimal useful dose and careful efficacy evaluation.Methods: This is a retrospective, Case-Control, descriptive and analytical study. Study population included women delivering in labor room of Gandhi Memorial Hospital associated with Shyam Shah Medical College, Rewa, from July 2015 to June 2016, then after data were compiled and assessed in department of pharmacology G.R. Medical College, Gwalior.Results: Results show that the use of oxytocin in labor stimulation can be detrimental to both the mother and the newborn, since they indicate that the use of oxytocin is associated with increased cesarean section rates both in primiparous and multiparous. Furthermore, it was also observed, a significant association between stimulation with oxytocin and low Apgar scores at 1 and 5 minutes both, of the newborns.Conclusions: Therefore, it may conclude that stimulation with oxytocin should not be used without any indication, but only in very specific cases, in which its use is particularly necessary. These results provide to health professionals a better understanding of the effects of the use of oxytocin during labor, which can be useful for decision-making in clinical practice.

Predictors of CABG Within One Year of Successful PTCA: A Retrospective, Case-Control Study

1997 ◽  
Vol 64 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Robert G Johnson ◽  
Cheryl Sirois ◽  
Robert L Thurer ◽  
Frank W Sellke ◽  
William E Cohn ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
One Year ◽  
Control Study

scholarly journals 791. Evaluation of NSAID Exposure as a Risk Factor for Clostridium difficile infection: A Propensity-Score-Matched Case-Control Study

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S439-S439
Author(s):  
Adam M Ressler ◽  
Alieysa Patel ◽  
Krishna Rao
Keyword(s):  
Logistic Regression ◽  
Risk Factor ◽  
Propensity Score ◽  
Case Control Study ◽  
Case Control ◽  
Comorbid Disease ◽  
Retrospective Case ◽  
Increased Risk ◽  
Study Population ◽  
Control Study

Abstract Background Exposure to certain medications, particularly antibiotics and proton pump inhibitors, has been associated with increased risk for Clostridium difficile infection (CDI). Studies have suggested an increased risk for CDI associated with exposure to certain non-steroidal anti-inflammatory drugs (NSAIDs). We conducted a retrospective case-control study to evaluate the risk for CDI associated with NSAID use. Methods The population included 1338 patients tested for CDI from February–December 2016 at the University of Michigan. NSAID use within 30 days of CDI testing was determined by chart review. Both scheduled and as-needed NSAID use met the definition for exposure, but aspirin use alone did not. Additional clinical data such as comorbid disease and baseline laboratory parameters were extracted through electronic query. A random forest model imputed missing data. A propensity score for NSAID use was developed via logistic regression and included gender, back pain, baseline serum creatinine, osteoarthritis, rheumatoid arthritis, serum albumin, and use of anticoagulant or antiplatelet medications. Cases were matched 1:1 with C. difficile negative controls by propensity score, with a matching caliper of 0.2 x standard deviation of the logit of the score. The final study population consisted of 1256 cases and their matched controls, however 6 cases could not be matched to controls as none had scores within the matching caliper. Conditional logistic regression was used to compare cases to controls. Results NSAID use was similar between the two groups on unadjusted analyses. The adjusted, multivariable model demonstrates that non-aspirin NSAID use is not a significant risk factor for CDI (P =.816), after adjustment for comorbid disease burden, age, and history of prior CDI (Table). Older age and prior CDI were independent risk factors for CDI (Table). Table Study population and modeling results Conclusion In this retrospective case-control study, non-aspirin NSAID use was not associated with an increased risk of CDI. To our knowledge, this is the first study of NSAID use as a risk factor for CDI that accounted for bias due to treatment assignment using a propensity score. Future studies should account for frequency or chronicity of NSAID use, which may affect the results. Disclosures Krishna Rao, MD, MS, Bio-K+ International, Inc. (Consultant)Merck and Co., Inc. (Research Grant or Support)Roche Molecular Systems, Inc. (Consultant)

scholarly journals EXPLORE THE EFFECT OF SMOKING ON THE VEP RESPONSE AMONG SMOKERS: AN ANALYTICAL STUDY.

2020 ◽  
Vol 4 (7) ◽  
Author(s):  
Ranjana Kumari ◽  
Rajiv Ranjan Prasad
Keyword(s):  
Visual Evoked Potential ◽  
Analytical Study ◽  
Evoked Potential ◽  
Case Control Study ◽  
Visual Evoke Potential ◽  
Evoke Potential ◽  
Case Control ◽  
Medical College ◽  
Male Subjects ◽  
Control Study

Aim: to explore the effect of smoking on the VEP response among smokers. Materials and Methods: The present prospective case-control study was conducted in the Department of Physiology, Neta Ji Subhash Medical College and Hospital, Patna, Bihar. Age matched 100 male smokers and 100 male non smokers were recruited. Data was statistically analyzed. Results: The male subjects selected with mean age of 45.76 years. Visual evoked potential was affected in smokers with prolongation of latency and decrease in amplitude of P100 in both the eyes than non smokers, with is statistically highly significant. Conclusion: concluded that Visual Evoke Potential was affected in smokers with prolongation of latency and decrease in amplitude of P100 in both the eyes when compared to non smokers. Keywords: Smokers, VEP, P100, Latency

Assessment of Craniofacial Morphology in Mouth Breathing Children. A retrospective case-control study

2019 ◽  
Vol 70 (10) ◽  
pp. 3649-3653
Author(s):  
David Angelescu ◽  
Teodora Angelescu ◽  
Meda Romana Simu ◽  
Alexandrina Muntean ◽  
Anca Stefania Mesaros ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Craniofacial Morphology ◽  
Respiratory Pattern ◽  
Control Group ◽  
Upper Lip ◽  
Retrospective Case ◽  
Oral Breathing ◽  
Facial Height ◽  
Control Study

The aim of this retrospective case-control study is to determine a possible correlation between breathing mode and craniofacial morphology. The study was carried out in the Department of Pedodontics,Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. The sample comprised 80 patients, age between 6 and 13 years, which were divided in two groups based on respiratory pattern: control group composed of 38 nasal breathing children and case group composed of 42 oral breathing children. Three quantitative craniofacial parameters were measured from the frontal and lateral photos: facial index, lower facial height ratio and upper lip ratio. The statistical analysis showed a significant higher facial index (p=0.006*) and an increase lower facial height (p=0.033*) for the oral breathers group. No differences in facial morphology were found between genders and age groups, when comparing the data between the same type of respiratory pattern children. Spearman�s rho Correlation show a significant positive correlation (p=0.002*) between facial index and lower facial height and a significant negative correlation between facial index and upper lip (p=0,005*). Long faces children are more likely to develop oral breathing in certain conditions, which subsequently have a negative effect on increasing the lower facial height by altering the postural behavior of mandible and tongue.

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