scholarly journals Chronopharmacology and drug prescribing pattern of physicians in a tertiary care hospital of North India

2018 ◽  
Vol 7 (3) ◽  
pp. 499
Author(s):  
Diwanshu Sharma ◽  
Pavan Malhotra
Keyword(s):  
Proton Pump ◽  
Beta Blockers ◽  
Accurate Determination ◽  
Tertiary Care ◽  
Drug Effects ◽  
North India ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Physician Prescribing

Background: Chronopharmacology is the science dealing with the optimization of drug effects and the minimization of adverse effects by timing medication in relation to the biological rhythm. This concept came into picture to make us understand about periodic and predictable changes in both desired effects and tolerance of medication Chronotherapeutics approach gives more accurate determination of the time when patients are at highest risk and in greatest need of therapy. This Chronopharmacological principle is used in the therapy of various diseases like cardiovascular diseases, allergy and many more. The objective of the study was to analyse whether chronopharmacological approach was being applied in clinical practice by comparing chronopharmacology of 4 drugs to their prescribing pattern by the physicians.Methods: This was observational study where 700 prescriptions written by physicians were audited. To study all the drugs would have been tedious so four commonly used drugs were chosen that is, Proton pump inhibitors, statins, Beta blockers and subcutaneous Insulin.Results: Results showed that chronopharmacological approach has been applied in the clinical field though physician didn’t have clear concept about chronopharmacology and it is relation to the prescribing. Despite this, maximum physician prescribing pattern was comparable to the chronopharmacological data except in case of Proton pump inhibitors.Conclusions: It is concluded that Chronotherapeutics approach gives more accurate determination of the time when patients are at highest risk and in greatest need of therapy. Nevertheless, this variation is only seldom considered by clinicians. If drugs are prescribed by following chronopharmacological approach it can prove beneficial to the patients as more of effectiveness of the drug and lesser side effects.

scholarly journals Drug prescribing pattern in patients of myocardial infarction in a tertiary care teaching hospital of North India

2020 ◽  
Vol 9 (9) ◽  
pp. 1357
Author(s):  
Akanksha Mehra ◽  
Nusrat K. Bhat ◽  
Sushil K. Sharma ◽  
Kanika Khajuria
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Family History ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Tertiary Care ◽  
North India ◽  
Drug Prescribing ◽  
Prescribing Pattern ◽  
History Of

Background: The term acute myocardial infarction (MI) should be used when there is evidence of myocardial necrosis in a clinical setting consistent with acute myocardial ischemia. Aims of this study were to assess drug prescribing pattern in patients of myocardial infarction and to compare prevalence of MI according to age, gender, diet, smoker or non-smoker, alcoholic or non-alcoholic, family history of cardiovascular disease.Methods: This observational study was conducted at department of pharmacology, in association with department of cardiology and included all patients of myocardial infarction visiting cardiology outpatient department or indoor patients and proforma was used to evaluate drug prescribing pattern.Results: Total 200 patients of acute myocardial infarction were analysed. Incidence of MI was more common in males (76%); age group 51-60 years (28.5%); non-vegetarians (68.5%); smokers (52.5%) and reduced physical activity (70.5%). 59.5% of patients had family history of cardiovascular disease. Commonly prescribed drugs were antiplatelets (100%) followed by hypolipidemic (99.5%), proton pump inhibitors (92%), antianginal (90.5%), anticoagulants (68.5%), thrombolytics (24.5%).Conclusions: This study provides insight towards drug prescribing pattern in MI patients. Most frequently prescribed drugs were antiplatelets followed by hypolipidemic and proton pump inhibitors. Patients had multiple risk factors and these can be reduced by lifestyle modifications.

scholarly journals Prescribing Pattern of Proton Pump Inhibitors (PPI) and Histamine Blockers in a Tertiary Care Hospital

2020 ◽  
Author(s):  
Anjali Manoj Goyal ◽  
Alpa Pragnesh Gor
Keyword(s):  
Drug Interactions ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Fixed Dose ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
H2 Blockers ◽  
Patient Department

Introduction: Gastric problems are the most common diseases seen in many countries for which majority of the population prefer Proton Pump Inhibitors (PPI) and Histamine (H2) Blockers. They are prescribed most commonly for Gastroesophageal Reflux Disease (GERD), Dyspepsia, Peptic Ulcer Disease, along-with medications like Non-Steroidal Antiinflammatory Drugs (NSAIDs) and other drugs. Concerns have been raised about the increasing costs associated with prescription of these drugs as they are often prescribed for minor symptoms and without clear indications. Prescribing pattern should be evaluated periodically to promote rational use of medicines. Aim: To assess the prescribing pattern of PPIs and H2 Blockers in Surgery and Medicine Department of a Tertiary Care Hospital. Materials and Methods: An observational study was conducted in a Tertiary Care Hospital, Karamsad over a period of one year from November, 2018 to October, 2019, among patients visiting to Out Patient Department (OPD) and In Patient Department (IPD) of Medicine and Surgery Department that were prescribed PPI and H2 Blockers. Total 1100 prescriptions and 1265 PPI, H2 Blockers were analysed. The data were analysed for socio-demographic variables along with details of PPI and H2 Blockers. co-prescribing drugs, Fixed Dose Combinations (FDCs) and drug interactions of each prescription was analysed. Results: In the study, PPI and H2 Blockers were prescribed more in males (54.36%). The predominant age group was 18-40 years (42%). Among studied drugs, most commonly prescribed single drug was Pantoprazole and FDC was Ranitidine + Domperidone. The drugs were most commonly prescribed through oral route (90.9%). They were most commonly prescribed along with an NSAID for gastroprotection (28.9%). Pharmacokinetic drug interactions were observed more in the study. Conclusion: This study showed that physicians prescribe PPI and H2 Blockers as a co-medication for gastroprotection. There is a need to increase documentation for prescribing PPI and H2 Blockers.

scholarly journals Prescribing pattern in outpatient department of neurosurgery in a tertiary care hospital of North India

2019 ◽  
Vol 7 (7) ◽  
pp. 2798
Author(s):  
Rehana Tabassum ◽  
Syed Sajad Hussain ◽  
Sajad Hussain Arif ◽  
Altaf Ramzan ◽  
Samina Farhat
Keyword(s):  
Lumbar Disc ◽  
Tertiary Care ◽  
Outpatient Department ◽  
North India ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Prescribing Pattern ◽  
Prescription Pattern ◽  
Mortality And Morbidity ◽  
Management Protocol

Background: The neurosurgical disorders are amongst the leading cause of global mortality and morbidity. Though surgical intervention is thought to be the main management protocol in the neurosurgical setup but drugs are being equally used especially in the outpatient setting. The present study was carried out in view of the sparse data available on prescribing pattern in neurosurgery.Methods: The present study was conducted by the department of pharmacology in outpatient department of neurosurgery in a tertiary care centre to look into the prescription pattern among these patients.Results: In 268 patients analyzed, mean age was 43.02±15.93 years and 52.23% were females. Majority of our participants (44%) were found to be of young to middle age group (21-40 years). The diagnosis among the study population was spread over large number of diseases. Lumbar Disc Prolapse (LDP) was found to be the leading cause of neurosurgical morbidity, amounting to 32%. As far as the prescription of various drugs in the outpatient of neurosurgery is concerned, Analgesics were the most common drugs prescribed constituting about 48% of the total drugs prescribed followed by GABA analogues and multivitamins which equally formed 41% of the total prescribed drugs.Conclusions: Although the prescription pattern studies among the outpatient neurosurgery patients are very scant, the analysis of prescription studies will be helpful to encourage the rational drug prescribing pattern.

scholarly journals Prospective Assessment of Prescribing Pattern of Proton Pump Inhibitors in A Tertiary Care Hospital in Chennai

2021 ◽  
Vol 66 (1) ◽  
pp. 38-42
Author(s):  
Maria K Manu ◽  
Feba John ◽  
Kolli Manikanteswara Rao ◽  
Dr. Samhitha Chetty ◽  
Dr Adarsh Surendranath ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Prospective Assessment

scholarly journals Attitude and Knowledge of Indian Emergency Care Residents towards Use of Proton Pump Inhibitors

2014 ◽  
Vol 2014 ◽  
pp. 1-6
Author(s):  
Biswa Mohan Padhy ◽  
Hemant Singh Bhadauria ◽  
Yogendra Kumar Gupta
Keyword(s):  
Health Care Providers ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Emergency Care ◽  
Tertiary Care ◽  
Developed Countries ◽  
North India ◽  
Care Hospital ◽  
Care Providers ◽  
First Choice

Objective. Several studies carried out in developed countries have reported disproportionately high usage of acid suppressive drugs, especially proton pump inhibitors (PPIs). However, systematic assessment of attitude and practices of health care providers towards the use of these drugs in developing countries is lacking. In this study, we assessed the knowledge, attitude, and preferences of resident doctors posted in the emergency department of a tertiary care hospital in North India, towards the use of PPIs. Methods. A questionnaire based survey was carried out. Results. Fifty resident doctors responded to the questionnaire. Thirty-six percent reported prescribing acid suppressive drugs for majority of their patients, while 12% prescribed them to almost all patients they attended. Acute gastritis was the most common indication for prescribing PPI/H2 blockers (50%). The majority of respondents (92%) regarded PPIs as their first choice in acid suppressive agents and 58% administered it through intravenous route. Knowledge about PPI related adverse effects was low. Conclusions. Emergency care residents in India also tend to overuse PPIs in a manner similar to their counterparts in developed countries. Specific measures may be helpful in preventing such practices.

scholarly journals Prescribing pattern of antibiotics in the department of pediatrics in a tertiary care medical college hospital in Northern India

2014 ◽  
Vol 5 (4) ◽  
pp. 69-72 ◽  
Author(s):  
Ravika Kanish ◽  
Kanchan Gupta ◽  
Shivani Juneja ◽  
HS Bains ◽  
Sandeep Kaushal
Keyword(s):  
Direct Cost ◽  
Pediatric Patients ◽  
Treatment Guidelines ◽  
Tertiary Care ◽  
Antibiotic Use ◽  
North India ◽  
Health Concern ◽  
Antibiotic Prescribing ◽  
Care Hospital ◽  
Prescribing Pattern

Background: Systemic antibiotics account for more than one?third of all prescriptions in children; hence, antibiotic prescriptions in children are a major public health concern. Moreover, data regarding rational antibiotic use in children is very limited. Hence, it is essential that the antibiotic prescribing pattern be evaluated periodically for its rationality of use and cost. The aim of our study is to identify the prescribing pattern and to carry out direct cost analysis of antibiotic use in the patients admitted in pediatrics department of a tertiary care hospital of North India. Methods: The study was conducted for two months (June, July, 2012) in pediatric ward and ICU. The data regarding patient demographics and antibiotic use was collected daily in a structured proforma. A descriptive analysis of the data was done. Results: A total of one hundred and ninety one patients were enrolled, most of them belonging to the age group 2?14 years. Majority of them were male pediatric patients (75.9%) with mean age of 4.6 years. On an average 1.9 AMAs were prescribed per patient. The most common AMAs prescribed were cephalosporins followed by aminoglycosides. The preferred route of administration was injectable (92%). The average direct cost of treatment per patient was estimated to be Rs. 3338. The percentage of drugs prescribed by generic name was 58%. Conclusions: Male pediatric patients have better access to tertiary medical care as compared to female pediatric patients. The average number of anti?microbials prescribed is 1.9 which is not too high. Newer generation of antibiotics are more commonly prescribed leading to increased cost of therapy. This baseline study will help in formulating an antibiotic policy and standard treatment guidelines for appropriate use of antibiotics. DOI: http://dx.doi.org/10.3126/ajms.v5i4.10213 Asian Journal of Medical Sciences 2014 Vol.5(4); 69-72

scholarly journals Drug utilization study of anti-hypertensive drugs at a tertiary care hospital

2020 ◽  
Vol 9 (8) ◽  
pp. 1241
Author(s):  
Pritpal Singh Ahluwalia ◽  
Mirza Shiraz Baig ◽  
Meenakshi Bhattacharya
Keyword(s):  
Tertiary Care Hospital ◽  
Beta Blockers ◽  
Tertiary Care ◽  
Brand Names ◽  
Prescribing Patterns ◽  
Care Hospital ◽  
Open Label ◽  
Prescribing Pattern ◽  
Medical College ◽  
Evidence Based Guidelines

Background: The increasing prevalence of hypertension influence the prescribing patterns of antihypertensive drug. Prescribing against evidence-based guidelines in hypertension treatment leads to the increase cost of medications and problems in providing affordable prescriptions to population. The aim of present study was to analyse anti-hypertensive prescribing pattern in Government Medical College and Hospital, Aurangabad, Maharashtra, India.Methods: Study was prospective, observational, open label and descriptive clinical study. It included 336 patients admitted in MICU during January 2018 to June 2019 fulfilling inclusion criteria.Results: 54.46% patients were between 51-70 years of age, followed by 33.63% in 31 to 50 age group. Of total enrolled hypertensive patients 69% patients had various comorbidities. Drug prescribed was 28.27% ARBs, 26.84% CCBs, 17.62% beta blockers, 6.14% high ceiling diuretics, 4.50% ACE inhibitors, 2.45% thiazide diuretics and 2.04% received alpha blocker. As monotherapy, 31.82% patients received telmisartan as most commonly prescribed drug followed by 27.31% patients received Amlodipine followed by other drugs. In combination therapy telmisartan and hydrochlorothiazide was prescribed most commonly followed by beta blocker and CCB and ARB and CCB. 33.60% of drugs were prescribed in generic names while 66.39% of drugs prescribed in brand names. Average number of drugs prescribed per prescription was 1.45 of which 33.60% of drugs were prescribed by generic names.Conclusions: With average number of drugs per prescription in hypertension 1.45, the study showed that poly pharmacy is unavoidable in hypertension due to associated comorbid conditions.

scholarly journals Uses of Proton Pump Inhibitors and Their Prescribing Pattern among the Patients Attending the Out-Patient Department at a Tertiary Care Hospital in Bangladesh

2020 ◽  
Vol 10 (1) ◽  
pp. 10-16
Author(s):  
Mohammad Quamrul Hasan ◽  
Nelson Taposh Mondal ◽  
Rukhsana Parvin ◽  
Irin Perveen
Keyword(s):  
Abdominal Pain ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Daily Basis ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Upper Abdominal ◽  
Patient Department

Background: Proton pump inhibitors (PPIs) are one of the most frequently prescribed classes of drugs in the world in the treatment of peptic ulcer, dyspepsia and gastro-oesophageal reflux. Objectives: To determine demographic, clinical response and practice characteristics of PPIs among the patients attending the out-patient department of a tertiary care hospital. Materials and Methods: In this prospective observational study 100 patients attending the out-patient department and taking oral proton pump inhibitors (PPI) for different symptoms and duration were included. Patient’s socio-demographic characteristics, PPI-related information (duration, frequency of use, doses and classes of PPIs) and symptomatic responses after taking PPI were noted. Drugs or diseases that influenced the intake of PPI were also recorded. Investigations done before or during PPI use and their findings were also noted. Results: Omeprazole (43%) and esomeprazole (35%) were the most frequently prescribed PPIs. Most of the patients (52%) were on PPI therapy for 1−3 months. Majority of the patients (72%) had taken PPIs on daily basis and 19% patients had taken irregularly or occasionally. Dosing frequency of PPIs prescribed were twice daily in most of the patients (77%). Sixty seven percent (67%) patients had taken PPI prescribed by doctors and 33% patients had taken PPI prescribed by non-doctors. Common indications for prescribing PPIs were heart burn (54%), upper abdominal pain/discomfort (38%) and bloating (33%). Symptoms reappeared after stopping the PPI in most of the patients (40%) and 35% patients had satisfactory relief of symptoms with PPI. Conclusions: Omeprazole and esomeprazole are the most frequently prescribed PPIs. Majority of the patients had taken PPIs on daily basis. In around one-third of the patients PPIs were prescribed by non-doctors. Common indications for prescribing PPIs were heart burn, upper abdominal pain/discomfort and bloating. Symptomatic responses varied after taking PPI and symptoms reappeared after stopping the PPI in most of the patients. J Enam Med Col 2020; 10(1): 10-16

Sign in / Sign up

Export Citation Format

Share Document