scholarly journals Analysis of gastrointestinal drugs in patients admitted in CCU and ICCU of a tertiary care hospital in Goa, India

2019 ◽  
Vol 8 (4) ◽  
pp. 782
Author(s):  
Shantadurga S. Kerkar ◽  
Padma N. Bhandare
Keyword(s):  
Peptic Ulcer ◽  
Tertiary Care ◽  
Essential Medicines ◽  
Fixed Dose ◽  
Care Hospital ◽  
Hospital Data ◽  
Prescribing Indicators ◽  
Medical College ◽  
Essential Drug List ◽  
Drug List

Background: Gastrointestinal (GI) diseases are a common problem worldwide. They are frequently encountered in non-critical as well as in critically ill hospitalized patients.Methods: This was a prospective and observational study conducted on patients admitted in CCU and ICCU of Goa Medical College and Hospital. Data was collected from the patients’ case records and was analysed referring to WHO prescribing indicators. Data was represented as Mean±SD, number and frequency.Results: A total of 2250 drugs were prescribed, out of which 376 (16.71%) were gastrointestinal drugs. Most common route of administration was oral 323 (85.90%). Prescription patterns of GI drugs were:  275 (73.14%) from National List of Essential Medicines, 20 (5.31%) as fixed dose combinations and 4 (1.06%) by generic names. Pantoprazole 183 (48.67%) was the most frequently prescribed drug for peptic ulcer in present study.Conclusions: From the findings of this study we noted that among the GI drugs used, those for peptic ulcer were the most commonly prescribed. Also majority were from the essential drug list. But prescribing by generic names was low. Review of drug utilization trends is a necessary aid to formulate and modify existing protocols and guidelines to improve treatment outcomes in a given setting.

scholarly journals Antibiotic Prescription Pattern Among The In-Patients Of A Tertiary Care Hospital

2020 ◽  
Vol 11 (SPL2) ◽  
pp. 132-136
Author(s):  
Raj shivaani M R ◽  
Preetha Selva
Keyword(s):  
General Surgery ◽  
Tertiary Care ◽  
World Health ◽  
Fixed Dose ◽  
Care Hospital ◽  
Exclusion Criteria ◽  
Prescribing Indicators ◽  
Prescription Pattern ◽  
Essential Drug List ◽  
Drug List

Antibiotics happen to be the most commonly used medicines, especially in developing countries like India, where infectious diseases are at a raise. Millions of antibiotics are prescribed by physicians all over India. The main objective of the present study is to analyze the prescription pattern of the antibiotics given to the in-patients of our hospital and to access the rationality of these prescriptions given, using the World Health Organization's core drug prescribing indicators. A total of 400 in- patients from Departments of Pediatrics, General Surgery, Obstetrics & Gynecology and Orthopedics were analyzed after screening for inclusion and exclusion criteria. The numbers of females are 248 (62%) and the males are 152 (38%) in a ratio of 1:1.63. 101 patients belonged to 40-60 years age group.  The pattern of antibiotic usage in the Department of Pediatrics, Obstetrics and Gynecology, General Surgery, Orthopedics was studied. The most common antibiotics prescribed were Cefotaxime (44%), Amoxicillin(38%) and  Cefazolin (38%, 24%) in Departments of Pediatrics, Obstetrics & Gynecology,  Surgery and Orthopedics respectively.   The total numbers of drugs prescribed were 1441 out of which 612 were antibiotics (43.09%). The number of antibiotics per prescription was 1.53. The average number of drugs prescribed per prescription was 3.6. The percentage of encounters with injections was 26.48%. The percentage of drugs prescribed by generic name is 36.2%. The percentage of drugs from the Essential Drug List was 92%. The percentage of fixed-dose combinations of antibiotics prescribed was 14.54%. Hence, in our study, though most of the drugs are given from the Essential List of Medicines, drugs given by a generic name is low. Physicians can be encouraged to prescribe more drugs by generic name. To conclude, antibiotic stewardship interventions have to be implemented to promote the judicious use of antibiotics to prevent adverse consequences.

scholarly journals Pattern of Cardiovascular Drugs Use in Outpatient Department in a Tertiary Care Hospital of Bangladesh

2018 ◽  
Vol 32 (2) ◽  
pp. 65-69
Author(s):  
Udoy Shankar Roy ◽  
AKM Monwarul Islam ◽  
Mohsin Ahmed ◽  
Murshidur Rahman Khan ◽  
Nihar Ranjan Sarker
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cardiovascular Drugs ◽  
Medical College Hospital ◽  
Outpatient Department ◽  
Essential Medicines ◽  
Fixed Dose ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College

Objective: The objective of the present study was to provide recent population-based information on use of cardiovascular drugs in outpatients in a tertiary care hospital of Dhaka, Bangladesh.Methods: A prospective study of cardiovascular prescriptions of Outpatient Department of Department of Cardiology of Shaheed Suhrawardy Medical college hospital Dhaka, Bangladesh was carried out. A total of 215 prescriptions were collected for the study in Shaheed Suhrawardy Medical College Hospital Dhaka, Bangladesh from July 2015 to June 2016. The prescriptions were evaluated for rationality based on WHO model list of essential medicines. The prescriptions were critically analyzed using predetermined parameters.Results: Out of 215 prescriptions collected, 120 drugs were found to be repeatedly prescribed. The results revealed that all single dose formulations prescribed were rationally in accordance with WHO essential drug list whereas fixed dose combinations prescribed remain questionable. A pattern of polypharmacy was clearly evident.Conclusion: Medications are a critical modality for prolongation and improved quality of life. Campaign and intervention should be focused on patients with more than three diagnostic cardiovascular conditions in order to minimize polypharmacy in patients particularly elderly.Bangladesh Heart Journal 2017; 32(2) : 65-69

scholarly journals The Assessment of Drug Utilization Study of Anticancer Drugs Using WHO Prescribing Indicators in a Government Tertiary Care Hospital of the Hyderabad - Karnataka Region of India

2019 ◽  
Vol 7 (7) ◽  
pp. 1203-1208 ◽  
Author(s):  
Asmatanzeem Bepari ◽  
Nayana Sakre ◽  
Ishrat Rahman ◽  
Shaik Kalimulla Niazi ◽  
Asmabi M. Dervesh
Keyword(s):  
Anticancer Drugs ◽  
Anticancer Agents ◽  
Tertiary Care ◽  
Inappropriate Drug ◽  
Care Hospital ◽  
Essential Drug ◽  
Prescribing Indicators ◽  
Rational Use ◽  
Essential Drug List ◽  
Drug List

BACKGROUND: Cancer is a major burden and threat to global society. A wide range of chemotherapeutic agents is extensively used to treat cancer at different stages. Inappropriate drug use may also lead to the raised cost of medical care, adverse drug effects, and patient mortality. Hence, in recent years, drug utilisation studies have become a potential tool to be used in the evaluation of different health care systems including cancer. AIMS: The objectives of the study were to identify the various types of cancer, the commonly prescribed drugs, rational use of anticancer drugs, and analyse the prescribing indicators in a tertiary care government hospital of India. MATERIAL AND METHODS: Newly diagnosed cancer and/or known case of carcinoma of either sex which required treatment/on treatment with chemotherapy aged > 18 yrs admitted in Radiotherapy Department from April 2016 to September 2016 were included in the study and analysed for prescribing indicators. RESULTS: The head & neck cancers were the prevalent cancers observed with more preponderance among males. Most of the patients were prescribed with a single anticancer drug. Cisplatin was the most commonly used cytotoxic drug followed by carboplatin, and antimetabolites. The most commonly used adjuvant drugs in our study were anti-emetics and anti-peptic ulcer drugs. Over 82% of anticancer agents were taken from the essential drug list and were prescribed in generic names, indicating rational use. CONCLUSION: Over 82% of anticancer agents were taken from the essential drug list and were prescribed in generic names, indicating rational use.

scholarly journals Study of utilisation trends of drugs in patients admitted with cardiovascular diseases at a tertiary care hospital in Goa

2017 ◽  
Vol 3 (12) ◽  
pp. 311
Author(s):  
Shantadurga S. Kerkar ◽  
Padma N. Bhandare
Keyword(s):  
Cardiovascular Diseases ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Healthcare Providers ◽  
Cardiovascular Drugs ◽  
Essential Medicines ◽  
Fixed Dose ◽  
Care Hospital ◽  
Mortality And Morbidity ◽  
Essential Drug List

<p class="abstract"><strong>Background:</strong> CVDs have emerged as a leading cause of mortality and morbidity in the world as well as in India. Drug usage is life saving and at times many drugs may be needed. Drug utilization studies aid to find the appropriateness of treatment, identify shortcomings if any, and provide a feedback to the healthcare providers to improve their management with drugs. So such types of studies are of vital importance in every hospital.</p><p class="abstract"><strong>Methods:</strong> This was a prospective, observational study of 180 patients with CVDs admitted in medicine and cardiology wards of a tertiary care hospital, conducted through case records and patients’ interviews. Data was represented as mean±SD, number and frequency.  </p><p class="abstract"><strong>Results:</strong> Incidence of cardiovascular diseases was more in males (56.67%) than the females (43.33%). Average number of drugs prescribed per patient was 9.16 and that of cardiovascular drugs was 5.08 ± 2.15. Antiplatelets (88.88%) were the most commonly prescribed cardiovascular drugs followed by hypolipidemics (82.22%). About 15.06% of injectables and 1.2% of fixed dose combinations (FDCs) were prescribed. Drugs prescribed by generic names were 1.6% and those from the National List of Essential Medicines were 92.79%.</p><p><strong>Conclusions:</strong> The results of this study suggested: polypharmacy, overuse of injections and low prescribing habits from essential drug list. Though antiplatelet, hypolipidemic use was higher, these are an essential part of treatment of certain CVDs. </p>

scholarly journals Drug Utilization Pattern by Using WHO Core Prescribing Indicators in Orthopedics and Obstetrics / Gynecology Departments of a Tertiary Care Hospital

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Naresh Karki ◽  
Ruban Raj Joshi ◽  
Buddhi Kumar Shrestha ◽  
Pravin Prasad
Keyword(s):  
Drug Utilization ◽  
Low Income ◽  
Tertiary Care ◽  
Care Hospital ◽  
Utilization Pattern ◽  
Essential Drug ◽  
Prescribing Indicators ◽  
Essential Drug List ◽  
Drug List ◽  
Prescription Form

Introduction: Drug utilization research is an important tool to facilitate rational use of drugs. In low income countries irrational use of drugs is a common problem like overuse of drugs and inappropriate use of antibiotics, leading to poor treatment outcome and increased burden of treatment. This study was conducted to provide understanding of drug utilization pattern by using WHO Core Prescribing Indicator. Methods: This study was conducted in Orthopedics and Obstetrics / Gynecology departments. Patients visiting these Out Patient Departments with at least one drug on prescription form were included in the study. Further, information related to WHO Core Prescribing Indicators were collected in pre-designed proforma. Results: Average number of drugs prescribed per prescription was 2.6. Means of number of drugs prescribed in Orthopedics and Obstetrics / Gynecology departments were 2.9 and 2.3 respectively (p < 0.001). Drugs prescribed in generic name and from essential drug list was 41.4% and 34.3% respectively. Prescription forms with generic name in Orthopedics department were significantly more compared to Obstetrics / Gynecology department (p = 0.00002). However, there was an increased tendency to prescribe drugs from essential drug list in Obstetrics / Gynecology department compared to Orthopedics department (p < 0.001). Conclusion: Drugs were prescribed by generic name and from essential drug list, but this was not sufficient to meet the ideal values of WHO Core Prescribing Indicator. Therefore, prioritization on prescribing drugs by generic name and from essential drug list by respective departments to achieve the standards of WHO needs to be encouraged.

scholarly journals Evaluation of rational drug use pattern using WHO prescribing indicators in a medical intensive care unit of a tertiary teaching hospital in Kerala, India

2017 ◽  
Vol 6 (6) ◽  
pp. 1328
Author(s):  
Shobha P. ◽  
Messaline Sunitha
Keyword(s):  
Tertiary Care ◽  
Care Hospital ◽  
Prescribing Practices ◽  
Essential Drug ◽  
Prescribing Pattern ◽  
Respiratory Problems ◽  
Essential Drug List ◽  
Drug List ◽  
Tertiary Teaching ◽  
Set Up

Background: ICU patients are exposed to more number of life saving drugs and face drug related problems like therapeutic failure, drug interactions and frequent adverse drug reactions. The cost of ICU hospitalisation and money spent on medicines is also a huge burden on these patients. A study of prescribing pattern in an ICU set up will serve as a medical audit to monitor and evaluate the prescribing practices to make it more rational and cost effective.Methods: A prospective observational study was carried out in a medical ICU of a tertiary care hospital. All the inpatients admitted in the medical ICU during the study period of 2 months were included in the study. The data obtained from the case sheets were used to assess the prescribing pattern and rationality of drug use.Results: A total of 101 patients were admitted in 2 months. The most common illness for which the patients (22) were admitted was respiratory problems. Average number of drugs per prescription was 6.9. Cardiovascular system (23.9%) drugs were the most frequently prescribed. Pantoprazole (77) was the single most commonly prescribed drug. 40% of the drugs were prescribed from the essential drug list. The average cost of medicines incurred per person in our study was 5126.33 in INR.Conclusions: Polypharmacy and unwanted prescription of proton pump inhibitors can be avoided by prescribing more generics and drugs from essential drug list.

scholarly journals Study on rationality of different fixed dose drug combinations in tertiary care hospital: an evaluation study

2020 ◽  
Vol 9 (3) ◽  
pp. 422
Author(s):  
Maddala Rajitha ◽  
Altaf Hussain Shaik ◽  
G. B. Simpson ◽  
A. Vishwa Shanthi
Keyword(s):  
Private Hospital ◽  
Tertiary Care ◽  
Evaluation Study ◽  
Drug Combinations ◽  
Fixed Dose ◽  
Care Hospital ◽  
Medical Sciences ◽  
Care Teaching ◽  
Essential Drug List ◽  
A Prospective Study

Background: The fixed dose drug combinations (FDCs) of drugs is defined as product of two or more active ingredients in a defined composition. There is a need to study the pattern of prescription from time to time to evaluate their rationality. In this context we undertook this study to know the prescription pattern of FDC in our setting. To study the rationality of different prescribed FDCs.Methods: This is a prospective study which is carried out in NIMRA Institute of medical sciences which is a tertiary care teaching private hospital. For this study we have collected one thousand prescriptions of patients for 3 months that is from 10th March 2017 to 25th of June 2017 including both in-patients as well as outpatients. Selection criteria of patients mainly basing on their willingness to give prescriptions. Institutional ethical committee permission was taken for the study. The prescribed FDCs were compared with the essential drug list of FDCs approved by Drugs Controller General of India, July 2018.  we have used descriptive statistics to analyze data. The percentage of FDCs used in each class and their contribution to overall FDCs were calculated.Results: In a total of 2952 drugs were prescribed, of this 747 were FDCs and 2205 were non FDCs. In the prescribed FDCs 89.2% drugs were rational and 10.8% drugs were irrational.Conclusions: From this study, we can conclude that 10.8% of irrational prescription of fixed dose drug combinations are prescribed in Nimra Institute of Medical Sciences which is a tertiary care teaching private hospital.

scholarly journals Drug utilization study in ophthalmology department at a tertiary care hospital

2021 ◽  
Vol 10 (4) ◽  
pp. 396
Author(s):  
Pritpal Singh Ahluwalia ◽  
Mirza Shiraz Baig ◽  
Amarnath Awargaonkar ◽  
Varsha Nandedkar
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Essential Medicines ◽  
Care Hospital ◽  
Open Label ◽  
Prescribing Pattern ◽  
Medical College ◽  
Rational Drug ◽  
Number Of Patients ◽  
Current Health Care System

Background: Drug utilisation studies in present clinical practice have played significant role to promote rational drug use in the current health care system. The aim of present study was to analyse the prescribing pattern of drugs for various ocular conditions in Ophthalmology Department of Government Medical College and Hospital, Aurangabad, Maharashtra, India.Methods: Study was prospective, observational open label and descriptive clinical study which included 100 patients in OPD and IPD during November 2018 to February 2019 fulfilling inclusion criteria.Results: Out of the 100 study subjects, 56% were males and 46% were females, with the maximum number of patients falling in the age group 61-80 years. 38.26% patients received antibiotics as most prescribed drug while 69 % patients received analgesics and 47% anti-inflammatory. Among the antibiotics prescribed, fluoroquinolones were the most prescribed antimicrobial class. WHO prescribing indicators as analysed from the data collected were: average number of drugs per prescriptions was 3.79. Percentage of medicines prescribed by branded name- 33.79% and generic were 66.21%. 54% of the total drugs prescribed were from the National List of Essential Medicines 2017.Conclusions: Ocular ailments and conditions are frequently associated with high levels of utilization of drugs for their treatment. Thus, analysis of utilization of these drugs becomes very essential. In the present study, the drugs prescribed at our tertiary care hospital were found rational.

scholarly journals A Study of drug utilization pattern in gynaecology out-patient department of a tertiary care hospital

2019 ◽  
Vol 7 (11) ◽  
pp. 4280
Author(s):  
Manish B. Nandeshwar ◽  
Ashish D. Chakravorty
Keyword(s):  
Drug Utilization ◽  
Rural Areas ◽  
Demographic Data ◽  
Tertiary Care ◽  
Brand Names ◽  
Care Hospital ◽  
Essential Drug ◽  
Essential Drug List ◽  
Drug List ◽  
Patient Department

Background: Gynaecological diseases are common in India because of socioeconomic, hygienic and literacy problems. Gynaecological drugs are one of the strong selling drugs in pharmaceutical market. Drug utilization research facilitate appropriate use of drugs in patient, minimize the adverse event and lead to better patient outcome. So, the present study was carried out to examine the patterns of drug prescription.Methods: A retrospective, observational study was done by collecting the prescriptions of the patients who attended the Gynaecology out-patient department in our institute for the period of six months. Total 300 prescription were collected and analysed. Patient’s demographic data, total number and category of drugs prescribed, percentage of individual drug and their dosage forms, drugs prescribed by generic name, brand names and percentage of drugs prescribed from essential drug list were analysed.Results: The mean age of presentation was 36.6±10.98 years. Among infective group breast abscess were common and among non-infective cases dysmenorrhea was most common. Out of 754 drugs prescribed, minerals were most commonly prescribed (42.70%) followed by antimicrobials (24.53%). Tablet form were prescribed more commonly (96.02%) followed by capsules (2%) and injections (1.06%). The average no. of drugs per prescription was 2.51±1.26 SD. Percentage of drugs prescribed by generic name were 98.01% and drugs prescribed from essential drug list were 85.41%.Conclusions: The overall drug use pattern in our study correlates with various gynaecological diseases. Majority of the women from rural background depend on primary health services for gynaecological diseases in their areas so, strengthening of gynaecological health care services reduce the morbidity among the women from rural areas. 

scholarly journals Prescribing pattern of antibiotics and susceptibility of pathogens in upper respiratory tract infections: a study from a tertiary care hospital

2020 ◽  
Vol 8 (4) ◽  
pp. 1221
Author(s):  
Sashwath Srikanth ◽  
Satyajit Mohapatra ◽  
P. Tharunya ◽  
R. Jamuna Rani
Keyword(s):  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Tertiary Care ◽  
Upper Respiratory Tract Infections ◽  
Care Hospital ◽  
Upper Respiratory Tract ◽  
Essential Drug List ◽  
Drug List ◽  
Upper Respiratory ◽  
Tract Infections

Background: Upper respiratory tract infections are mostly caused by viruses and are self-limiting. But it is seen that drug therapy is restored to many of them without adequate justifications. Sometimes multiple drug therapy imposes high cost burden on patients. Use of antibiotics in URTI patients have led to rise in bacterial resistance. So, this study was aimed to analyse the prescription pattern in upper respiratory tract infections and the antibiotic susceptibility of the isolated organisms.Methods: An observational cross-sectional study was conducted in a tertiary care hospital for a period of three months. Based on the inclusion and exclusion criteria sixty patients were selected. Prescriptions of these patients were collected and analysed for the various WHO prescription indicators like average number of drugs per encounter, percentage of drugs prescribed by generic names, percentage of drugs prescribed as injection, drugs form the essential drug list etc. The swabs were collected from the site of infections and were analysed for the bacterial growth. Also, the antibiotic susceptibility of these organisms was tested.Results: A total of sixty prescriptions were collected and analysed. The average number of drugs per prescription was 2.21. Antimicrobials were prescribed in 90% of cases. Approximately 50% cases the combination of amoxicillin and clavulanic acid was prescribed. The percentage of drugs prescribed by generic names was 87% and 68% drugs were form the essential drug list. The culture report of the specimen collected from the swabs showed that only 50% of cases were of some bacterial origin. And the organisms isolated were less susceptible to the antibiotics that were prescribed.Conclusions: This study of prescribing patterns in patients gives appropriate feedback and awareness among health care providers. Rationale prescribing practice will prevent antibiotic resistance and reduction in the adverse drug reactions. 

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