scholarly journals Drug utilisation pattern in geriatric patients of a teritiary care teaching hospital: a retrospective study

2019 ◽  
Vol 8 (11) ◽  
pp. 2450
Author(s):  
Naveen Kumar Tamma ◽  
Prasanth Kumar Patnaik ◽  
Srinivasu Karedla
Keyword(s):  
Respiratory Tract ◽  
Tertiary Care ◽  
Continuous Medical Education ◽  
Brand Names ◽  
Upper Respiratory Tract ◽  
Prescribing Practices ◽  
Gastrointestinal Infections ◽  
Prescribing Pattern ◽  
One Year ◽  
Tract Infections

Background: The objective of the study was to assess the prescribing pattern of drugs in geriatrics patient in a tertiary care hospital.Methods: A retrospective observational study was conducted by department of Pharmacology for a period of one year in patients above 65 years from case sheets of medical record section. WHO basic indicators were used for studying the prescribing pattern of drugs.Results: A total of 200 patients were included in the study. Respiratory tract and gastrointestinal infections were most commonly found among patients of geriatric age group. Among antibiotics ceftriaxone, cefixime, ampicillin, amoxicillin, azithromycin, ciprofloxacin, cotrimaxazole for upper respiratory tract infections and rantidine, norfloxacin for gastrointestinal tract infections were maximum utilized. Polypharmacy was prevalent and majority of drugs prescribed were by brand names because of free supply of drugs.Conclusions: There is a need to bring changes in the prescribing practices with particular emphasis on generic drug and restricting polypharmacy. Also antibiotic policy needs to be introduced in the hospital and continuous medical education besides evidence based medicine approach for rationale use of drugs.

scholarly journals Prescribing Pattern of Drugs in Acute Respiratory Tract Infection in Children aged 1 To 5 Years At Tertiary Care Teaching Hospital

2018 ◽  
Vol 11 (4) ◽  
pp. 1903-1911 ◽  
Author(s):  
Sujata Jadhav ◽  
Chitra Khanwelkar
Keyword(s):  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Tertiary Care ◽  
Age Groups ◽  
Essential Medicine ◽  
Influenza Viruses ◽  
Brand Names ◽  
World Health ◽  
Prescribing Pattern ◽  
Tract Infections

Acute respiratory tract infections (ARTI) are very common in all age groups. Childhood respiratory tract infections are responsible for considerable morbidity and mortality. It is significant health problem in India also. The World Health Organization (WHO) estimates that 2 million children under five years of age die due to pneumonia. Majority of ARTIs have viral etiology. Rhinoviruses, respiratory syncytial viruses, parainfluenza and influenza viruses, human metapneumovirus, and adenoviruses are main causative agents. Among bacteria, group A streptococci, Corynebacterium diphtheriae, N. meningitides, H. influenzae, pneumococcus and Staphylococcus aureus are responsible for ARTIs. Drug utilization studies help to understand the pattern of prescription in that particular area for specific conditions.We included children from one to five years of age, diagnosed as ARTI and evaluated 298 prescriptions given to these children. Analysis of these prescriptions was done as well as they are compared with WHO prescription indicators. Cough (96%), fever (93%) and rhinitis (82.5%) were common symptoms observed, but sore throat, earache and breathlessness were also present in these children. Average number of drugs prescribed was 4.1/patient. Following drugs were prescribed, Antipyretics 98.3%, antimicrobials 91.3%, antihistaminics and cough syrups in 75.2%, Leukotriene antagonist in 25.1% patients, Vitamin B complex 11% and glucocorticoids 4.6%. All drugs were prescribed by brand names and not by generic name. 97.3% prescribed drugs were from national list of essential medicine. We found overuse of antimicrobials in our study. Educational programs are needed in order to bring rational use of antimicrobials. At the same time awareness in parents also should be done regarding antimicrobial use.

scholarly journals Adverse drug reactions observed in treatment of gastro intestinal and respiratory tract infections: a prospective analysis

2019 ◽  
Vol 9 (1) ◽  
pp. 134
Author(s):  
Laxmipathi Kodam ◽  
Naveen Kumar Tamma ◽  
Janardhan Marupaka ◽  
Srinivasu Karedla
Keyword(s):  
Gastrointestinal Tract ◽  
Respiratory Tract ◽  
Adverse Drug Reactions ◽  
Respiratory Tract Infections ◽  
Adverse Drug Reaction Reporting ◽  
Tertiary Care ◽  
Brand Names ◽  
Drug Reactions ◽  
One Year ◽  
Tract Infections

Background: The aim of the study was to observe common adverse drug reactions in treatment of gastro intestinal and respiratory tract infections in a tertiary care hospitals.Methods: A prospective observational study was conducted by Departments of Pharmacology for a period of one year from prescriptions and case sheets of medical record section. Adverse drug reaction reporting forms and alert cards were used for reporting.Results: The drugs most commonly used for gastrointestinal tract and respiratory diseases are tablets norflox 400 mg, norflox-tz, taxim 200 mg, IV amikacin and iv amoxicillin (500 mg) and clavulanic acid (125 mg) combination. Systems affected by use of above drugs were skin and gastrointestinal tract. Urticaria on skin, abdominal pain, itching in genital area, ulcer on oral mucosa are the common adverse drug reactions observed.Conclusions: Drugs used for common gastrointestinal tract and respiratory tract infections alert cards should be issued to patients when prescribing and adverse drug reactions should be reported to higher centres. Brand names causing adverse reactions should be monitored regularly and their further usage should be based on signals from other centres. All tertiary care hospitals should have antimicrobial guidelines policy to reduce adverse drug reactions.

Evaluation of Parental Knowledge, Attitudes and Practices Regarding Antibiotic Use in Acute Upper Respiratory Tract Infections in Children in a Tertiary Care Hospital in Turkey

2021 ◽  
Author(s):  
Aslınur Albayrak ◽  
Nazmi Mutlu Karakaş ◽  
Bensu Karahalil
Keyword(s):  
Antibiotic Resistance ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Tertiary Care ◽  
Antibiotic Use ◽  
Upper Respiratory Tract Infections ◽  
Care Hospital ◽  
Upper Respiratory Tract ◽  
Upper Respiratory ◽  
Tract Infections

Abstract BackgroundUpper respiratory tract infections (URTIs) are common in children. Most URTIs have been shown to be of viral origin. Inappropriate use of antibiotics is one of the main causes of antibiotic resistance. The problem of unnecessary antibiotic use among children is a concern for antibiotic resistance in low- and middle-income developing countries.MethodsOur study is a cross-sectional survey study. It was carried out between 14 December 2020 and 1 April 2021 for parents over 18 years of age with a child under 18 years’ old who applied to the general pediatrics outpatient clinics of Gazi University Faculty of Medicine Hospital Department of Pediatrics.Results554 parents responded to the questionnaire. A total of 15.7% of parents stated to use antibiotics in any child with fever. 37% of parents believed that antibiotics could cure infections caused by viruses. 6.3% of parents declared that they put pressure on pediatricians to prescribe antibiotics. 85.6% of the parents stated that they never gave their children non-prescription antibiotics when they had a high fever. 80.9% of them declared that they never used past antibiotics in the presence of a new infection. Female gender, high level of education, high income level and low number of antibiotics used in the last 1 year were found to be statistically significant with the better knowledge level of the parents (p <0.05).ConclusionAccording to the results of our study of parents' lack of knowledge about antibiotics in Turkey, though generally it shows proper attitude and behavior. It shows that some of the restrictions imposed by the National Action Plan are partially working. However, it is still necessary to continue to inform parents, pediatricians and pharmacists about the use of antibiotics, and to be more sensitive about the prescribing of antibiotics, and if necessary, sanctions should be imposed by the state in order to prevent unnecessary antibiotic prescriptions.

scholarly journals Prescribing pattern of antibiotics in pediatric department of a tertiary care teaching hospital

2020 ◽  
Vol 9 (5) ◽  
pp. 782
Author(s):  
Nalini G. K. ◽  
Neelamma . ◽  
Prasanna Kumar D. G. ◽  
Deepak P. ◽  
Sahana G. N. ◽  
...  
Keyword(s):  
Respiratory Tract Infections ◽  
Tertiary Care ◽  
Age Group ◽  
Gastrointestinal Infections ◽  
Prescribing Pattern ◽  
Pediatric Department ◽  
Prescription Pattern ◽  
Tract Infections ◽  
A Prospective Study

Background: Prescription is an order from doctor for medicine. Rational use of medicines requires that "patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them and their community". Irrational use of medicines is a major problem worldwide. This leads to serious morbidity and mortality also leads to reduction in the quality of treatment due to antibiotic resistance. Evaluation of prescribing pattern will help in minimizing adverse drug reactions, resistance among children. Also help to know the attitude of the physicians towards prescribing. Aim of the present study was to evaluate the prescription pattern of antibiotics in paediatric inpatients of Hassan institute of Medical Sciences.Methods: A prospective study, conducted among 110 patients below the age of 18 years and being treated with antibiotics were included in our study. The results were analyzed using descriptive statistics.Results: Out of 110 patients, female (58) and male (52) are enrolled in the study from inpatient paediatrics department, majority of patients belonged to age group of 0-5 years (74%), respiratory tract infections 29 (35%) , gastrointestinal infections 26 (22%) and central nervous system in 9 (11%). Out of 227 antimicrobial agent, about 83.48% were cephalosporins, followed by ciprofloxicin (33.94%), amoxicillin (32.11%), and amikacin (6.42%).Conclusions: Cephalosporins (ceftriaxone) were most commonly used antibiotic, which covers gram positive, gram negative and anaerobic organism.

scholarly journals IDENTIFICATION OF DRUG-RELATED PROBLEMS IN PATIENTS WITH UPPER ACUTE RESPIRATORY TRACT INFECTIONS IN TEBET SUBDISTRICT HEALTH CENTER

2020 ◽  
pp. 69-73
Author(s):  
ATIKA WAHYU PUSPITASARI ◽  
OLYVA CESSARI LARAS SERUNI ◽  
LINA NADHILAH
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Health Center ◽  
Drug Dosage ◽  
Upper Respiratory Tract ◽  
Drug Related Problems ◽  
Prescribing Pattern ◽  
Cross Sectional ◽  
Tract Infections

Objective: Acute respiratory tract infection (ARTI) is common and has the highest death rate in children, especially in growing countries such asIndonesia. The aim of the research is to identify drug-related problems (DRPs) in pediatric ARTI patients based on the DRP classification by Cipolle,Strand, and Morley, which included categories such as unnecessary drug therapy, need additional therapy, ineffective drug, dosage adjustments suchas too low or too high, and adverse drug reaction which is drug interaction.Methods: The design of the study was cross-sectional and descriptive with a retrospective method. The sample of the study was the overall prescriptionsto upper respiratory tract infection patients in Tebet Subdistrict Health Center from July to December 2018 that fulfilled all of the inclusion criteria,using the total sampling method. Total samples that were analyzed were from 179 sheets of prescription with a total of 498 prescriptions.Results: The results of the research based on each parameter were inaccurate drug selection (9.5%), inaccurate indication (12.8%), mismatched dose(79.9%), and drug interaction (0.6%).Conclusion: DRPs in ARTI pediatric patients resulted in a high-risk condition so that the health facilities need to improve their prescribing pattern andmonitor and manage each therapy as well as do a routine prescription assessment to minimize the incidence of DRPs and achieve a rational drug usage.

scholarly journals A study on prescribing trends in respiratory tract infections in a tertiary care hospital

2019 ◽  
Vol 1 (2) ◽  
pp. 50-56
Author(s):  
Omair sohail ahmed ◽  
Mohammed Abdul Ali ◽  
Omer wasiq ◽  
Syed Mujtaba Pasha ◽  
Mohammed Mukaram ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Tertiary Care ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Drug Store ◽  
Stock Control ◽  
Points Of Interest ◽  
Prescribing Trends ◽  
Tract Infections

The drug utilization pattern of respiratory tract infections to assess the rational prescribing pattern at tertiary care teaching hospital, endorsing drugs by mark names may undermine a portion of the objectives of fundamental solution idea. Recommending by nonexclusive name causes the clinic drug store to have a superior stock control. This will likewise assist the drug store with purchasing drugs on contract premise, as the quantity of brands is less, in this manner decreasing the perplexity among drug specialists while apportioning. Bland medications are regularly more temperate than the marked ones. With respect to recommending of FDCs, Potential points of interest of FDC's incorporate lessened reactions, expanded patient consistence, cooperative energy and expanded adequacy and decreased cost, potential impediments incorporate unbendable settled measurements proportion, contrary pharmacokinetics, expanded harmfulness, doctor and drug specialist's obliviousness.

scholarly journals Clinical study of lower respiratory tract infections in children attending a tertiary care hospital

2017 ◽  
Vol 4 (5) ◽  
pp. 1733
Author(s):  
Venkata Krishna Munagala ◽  
Ramisetty M. Uma Mahesh ◽  
Jithendra Kandati ◽  
Munilakshmi Ponugoti
Keyword(s):  
Respiratory Tract ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Bacterial Pathogens ◽  
Tertiary Care ◽  
Care Hospital ◽  
Upper Respiratory Tract ◽  
Lower Respiratory Tract Infections ◽  
Cross Sectional ◽  
Tract Infections

Background: WHO estimated burden of respiratory tract infections in 2010, estimates four and half million deaths due to respiratory tract infections among children every year. In India, 1.2 million deaths have been reported among children due to RTI among 5.9 million deaths globally. Lower respiratory tract infections are most common causes of death than upper respiratory tract infections. Pneumonia and Bronchiolitis are most common types of LRTI in children. Pneumonia accounts for most of the deaths in children < 5 years of age. The present study was undertaken with an objective to know the various types of lower respiratory tract infections in children less than 12 years of age. The study also aims to know the various bacterial agents causing respiratory tract infections with their antibiotic susceptibility.Methods: Hospital based, prospective cross-sectional study was conducted for a period of one year and 375 children were enrolled. Demographic, clinical history and examination was done and signs and symptoms noted. All necessary investigations were performed and followed regularly for management and outcome.Results: Incidence of LRTI in the study was 9.76% with male preponderance (65.33%) and most common among children in 1-4 years age group. Ratio of males to females was 1.9:1. 73.6% of cases were in low socio-economic group, 35.2% were found with PEM-I grade and 18.13% had no immunization coverage. Cough and breathlessness were the major symptoms and respiratory distress and clubbing were major signs in the study. Bronchopneumonia was the commonest cause (38.7%) followed by bronchiolitis and Allergic bronchitis. 18.45 of cases had anemia and Leucocytosis was also present. Pulmonary infiltration was the major finding in the X-ray of chest. Streptococcus pneumoniae and Klebsiella pneumoniae were the common bacterial pathogens isolated.Conclusions: To conclude, our study clearly highlighted the various types of clinical presentations, risk factors and different types of LRTI in children <12 years of age. Understanding a clear knowledge of the etiology and bacterial pathogens clearly provides guidance for the physician in management and clinical outcome. 

scholarly journals Prescribing pattern of antibiotics and susceptibility of pathogens in upper respiratory tract infections: a study from a tertiary care hospital

2020 ◽  
Vol 8 (4) ◽  
pp. 1221
Author(s):  
Sashwath Srikanth ◽  
Satyajit Mohapatra ◽  
P. Tharunya ◽  
R. Jamuna Rani
Keyword(s):  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Tertiary Care ◽  
Upper Respiratory Tract Infections ◽  
Care Hospital ◽  
Upper Respiratory Tract ◽  
Essential Drug List ◽  
Drug List ◽  
Upper Respiratory ◽  
Tract Infections

Background: Upper respiratory tract infections are mostly caused by viruses and are self-limiting. But it is seen that drug therapy is restored to many of them without adequate justifications. Sometimes multiple drug therapy imposes high cost burden on patients. Use of antibiotics in URTI patients have led to rise in bacterial resistance. So, this study was aimed to analyse the prescription pattern in upper respiratory tract infections and the antibiotic susceptibility of the isolated organisms.Methods: An observational cross-sectional study was conducted in a tertiary care hospital for a period of three months. Based on the inclusion and exclusion criteria sixty patients were selected. Prescriptions of these patients were collected and analysed for the various WHO prescription indicators like average number of drugs per encounter, percentage of drugs prescribed by generic names, percentage of drugs prescribed as injection, drugs form the essential drug list etc. The swabs were collected from the site of infections and were analysed for the bacterial growth. Also, the antibiotic susceptibility of these organisms was tested.Results: A total of sixty prescriptions were collected and analysed. The average number of drugs per prescription was 2.21. Antimicrobials were prescribed in 90% of cases. Approximately 50% cases the combination of amoxicillin and clavulanic acid was prescribed. The percentage of drugs prescribed by generic names was 87% and 68% drugs were form the essential drug list. The culture report of the specimen collected from the swabs showed that only 50% of cases were of some bacterial origin. And the organisms isolated were less susceptible to the antibiotics that were prescribed.Conclusions: This study of prescribing patterns in patients gives appropriate feedback and awareness among health care providers. Rationale prescribing practice will prevent antibiotic resistance and reduction in the adverse drug reactions. 

scholarly journals Prescribing pattern of anti diabetic drugs in patients suffering from type 2 diabetes mellitus with co-existing hypertension in a tertiary care teaching hospital

2018 ◽  
Vol 7 (4) ◽  
pp. 761
Author(s):  
Jay Kumar Sharma ◽  
Shailesh P. Parmar
Keyword(s):  
Diabetes Mellitus ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Brand Names ◽  
Prescribing Pattern ◽  
Cross Sectional ◽  
Age Ratio ◽  
Male Patients ◽  
One Year

Background: Diabetes mellitus and hypertension frequently co-exist in a patient. In such patients, the risk of complications, morbidity and mortality increases. One should be careful in management and choosing drugs. Authors undertook this study to understand the prescribing pattern of the physicians in diabetic hypertensive patients.Methods: This cross sectional, observational study was conducted in type 2 diabetic outdoor patients with co-existing hypertension, for duration of one year. We used descriptive statistics to analyze data of 615 patients to determine prescribing pattern of drugs.Results: 93.17% of patients were more than 40 years of age. Ratio of female to male patients was 1.30. Mean duration of diabetes was 5.81 years. Multi drug anti diabetic regimes (54.47%) were common than monotherapy (43.90%). Commonly prescribed anti diabetic drug groups were biguanides (89.27%), Sulfonylureas (43.90%) and insulin (15.28%). Metformin (89.27%), glibenclamide (29.11%) and insulin (15.28%) were commonly prescribed anti diabetic drugs. Metformin was the most common monotherapy drug and biguanide + sulfonylurea was the most common two drug combination. Commonly prescribed drugs for co-morbid conditions were enalapril (83.41%), aspirin (30.41%), amlodipine (29.76%) atorvastatin (27.32%) and famotidine (26.34%). Average number of drugs prescribed in a prescription was 4.65. Prescriptions with injections were 15.93% and with brand names were 13.15%.Conclusions: Prescribing pattern of drugs was as per current practices and recommendations of guidelines. Still, there is room for improvement in choice of drug, prescribing drug with generic name and choosing drug from essential medicine list.

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