scholarly journals Drug utilization study of antipsychotics among schizophrenia patients in a tertiary care teaching hospital: a retrospective observational study

2020 ◽  
Vol 9 (6) ◽  
pp. 971
Author(s):  
Sahana M. Mogali ◽  
Basavaraj C. Kotinatot
Keyword(s):  
Observational Study ◽  
Drug Utilization ◽  
Atypical Antipsychotics ◽  
Demographic Data ◽  
Tertiary Care ◽  
Mood Stabilizers ◽  
Retrospective Observational Study ◽  
Utilization Pattern ◽  
Drug Utilization Study ◽  
One Year

Background: Aim of the study was to evaluate the drug utilization pattern of antipsychotics in schizophrenia patients in a tertiary care hospital.Methods: A retrospective observational study was conducted over a period of one year. Demographic data and drug utilization pattern of antipsychotics was collected from the surveyed prescriptions. Using WHO prescribing indicators data was analysed. Results were expressed in percentage.Results: Out of 300 prescriptions analysed, males were 58% and females 42%. Majority of schizophrenia patients were in age group of 15 to 45 years 70.33%. Olanzapine 75% was most common antipsychotic drug prescribed followed by risperidone 10.7%. Haloperidol 9.6%, fluphenazine 3.7% and chlorpromazine 1% were the other antipsychotics prescribed. Atypical antipsychotics 85.7% were commonly prescribed than conventional ones 4.3%. Concomitant drugs prescribed were anticholinergics, antihistaminics, sedative-hypnotics, antidepressants, mood stabilizers, antiulcer drugs and vitamin B complexes. Average number of drugs prescribed per prescription 3.26.Conclusions: Nowadays atypical antipsychotics are preferred over conventional ones because of their less side effects. Drug utilization study helps in rational usage of drugs important for patient care.

scholarly journals Depression and its Cure: A Drug Utilization Study from a Tertiary Care Centre of Western Nepal

2011 ◽  
Vol 1 (5) ◽  
pp. 144-152 ◽  
Author(s):  
Indrajit Banerjee ◽  
Bedanta Roy ◽  
Indraneel Banerjee ◽  
Brijesh Sathian ◽  
Monami Mondal ◽  
...  
Keyword(s):  
Major Depression ◽  
Drug Utilization ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Tertiary Care ◽  
Hospitalized Patients ◽  
Care Centre ◽  
Utilization Pattern ◽  
Monthly Income ◽  
Drug Utilization Study ◽  
Tertiary Care Centre

Background: According to WHO, it is estimated that major depression would be the second most leading cause of disability in the world by 2020. Drug utilization study is defined as study of the marketing, distribution, prescription and use of drugs in a society highlighting on the resulting medical, social and economic consequences. The main objective of this study was to find the utilization pattern of antidepressants prescribed in a tertiary care centre with major depression in hospitalized patients of Western Nepal.Methods: A hospital based observational study was done between 1st October 2009 and 31st March 2010 at Psychiatry Ward of Manipal Teaching Hospital, Nepal. Both qualitative and quantitative data was collected from bed side. The outcome variables were essential drug, generic and trade, treatment, groups of antidepressants and antidepressants used. The explanatory variables were age, gender, monthly income, employment of the patient. Z test and logistic regression was used for the analysis. P-value < 0.05 was considered to be statistically significant. This is the first study done to understand the utilization pattern of antidepressant drugs in hospitalized patients in Nepal.Results: Among the 240 psychiatric patients studied, 38 (15.8%) cases were suffering from major depression. Male and female patients were 44.7% and 55.3% respectively, 95% CI [28.9, 60.5 and 39.5, 71.1]. Depression was more common in housewives (42.1%) followed by teachers 18.4% and students 10.5%. Fluoxetine was the commonest antidepressants to be prescribed 42.1% followed by Amitriptyline 26.3%, Trazodone 21.1% etc. Psychiatrists has a tendency of prescribing essential drugs if monthly income <10000, 1.063 times as compared to monthly income >10000, 2.63 times more in Hindus and 1.197 times more in Brahmins than any other ethnic groups. 9.179 times more tendency of prescribing antidepressants by trade names in case of unemployed patients as compared to employed patients in Nepal.Conclusion: According to the utilization pattern of antidepressants it was found that among the Selective serotonin reuptake inhibitors Fluoxetine was used relatively higher than conventional drugs like Tricyclic antidepressants, recommend that there is a trend of using Typical antidepressants drugs for depression rather than Newer antidepressants.DOI: http://dx.doi.org/10.3126/nje.v1i5.6152 Nepal Journal of Epidemiology 2011;1 (5):144-52 

scholarly journals Drug utilization pattern in sick paediatric patients: analysis for rationality and other aspects

2017 ◽  
Vol 6 (12) ◽  
pp. 2815
Author(s):  
Ambrish Gupta ◽  
Prashant Maheshwari ◽  
K. K. Dokania ◽  
J. J. Tambe
Keyword(s):  
Observational Study ◽  
Drug Utilization ◽  
Pediatric Patients ◽  
Research Work ◽  
Retrospective Observational Study ◽  
Utilization Pattern ◽  
Rational Prescribing ◽  
Paediatric Patients ◽  
Specific Objective ◽  
Set Up

Background: The aim of this research work was to study the drug utilization pattern in the indoor paediatric patients with specific objective to analyse the rationality status of prescriptions and other aspects.Methods: A retrospective observational study was conducted for a period of 6 months. We analysed 120 prescriptions for the rationality status and different other parameters using Phadke’s criteria and W.H.O. prescribing indicators.Results: In our study out of total 120 prescriptions; 90 were rational followed by semi-rational and irrational. Average number of drugs prescribed was 5.39 drugs per prescription. Out of total FDCs prescribed 30% were irrational. Most commonly prescribed drug was anti-bacterial. Among anti-bacterial, most commonly prescribed anti-bacterial was from the cephalosporin group; which is categorized as “WATCH” category in W.H.O.-EML for children, March 2017.Conclusions: Though the results in present study reflect rational prescribing in pediatric patients in our hospital set up, there is still scope of improvement in prescription habits like avoid prescribing unnecessary drugs and irrational FDCs. There is also need of prescribing by generic names.

scholarly journals Drug utilization study in patients visiting psychiatric OPD in tertiary care hospital

2021 ◽  
Vol 10 (4) ◽  
pp. 342
Author(s):  
Ujwala P. Gawali ◽  
Prashant S. Mishra ◽  
Salman H. Rizvi ◽  
Sukhmeen Kaur
Keyword(s):  
Drug Utilization ◽  
Atypical Antipsychotics ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
World Health ◽  
Psychiatric Diseases ◽  
Care Hospital ◽  
Drug Utilization Study ◽  
Cross Sectional

Background: The illness due to psychiatric diseases and behavioral disorders is enormous, but it remains under represented by conventional public health statistics; which mainly targets mortality more than morbidity or dysfunction. The drug utilization study was conducted to find out problems and provide feedback to prescribers so as to create awareness about irrational use of drugs. This study was conducted in psychiatry outpatient department (OPD) of a tertiary care hospital.Methods: A prospective, observational and cross-sectional study was conducted in Department of Pharmacology in collaboration with department of psychiatry in a tertiary care hospital. Patients fulfilling the inclusion criteria visiting psychiatric OPD from 01 October 2018 to 31 December 2018 period of 3 months were enrolled in the study. Assessment of the prescriptions was done as per the ICD-10 criteria and World Health Organization-indicators for rational use of drugs (WHO-INRUD).Results: Among total 390 prescriptions; 71.54% was males and 28.46% were females. All the drugs were oral formulations. The burden of diseases are depression 35.89%, anxiety 20.51%, schizophrenia 18.97% and bipolar disorder 11.28% and other psychiatric diseases were 13.33%. Olanzapine was the most common drug which was prescribed followed by alprazolam. Total 1,140 drugs were prescribed out of which 86.32% was psychotropic drug and 13.68% were other like vitamin B-complex, analgesics, anta-acids, antibiotics and NSAIDS. The Most common prescribed class was atypical antipsychotics 26.31% followed by benzodiazepines 20.26%, antipsychotics 19.74%, tricyclic antidepressants 8.16%, anticonvulsants 9.21%, antiepileptics 2.37% and lastly selective serotonin reuptake inhibitors.Conclusions: Atypical antipsychotics was most commonly prescribed drug followed by benzodiazepines. All the drugs were prescribed by their generic names which suggests awareness among prescribers regarding WHO policies for generic prescribing.

scholarly journals A Drug Utilisation Study of Antihyperglycaemic Agents in a Rural Tertiary Care Hospital

2017 ◽  
Vol 6 (1) ◽  
pp. 1357
Author(s):  
Naidu CDM ◽  
Vardhan A ◽  
Bankar MA ◽  
Sharma S ◽  
Raghuvanshi VS ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Demographic Data ◽  
Tertiary Care ◽  
General Medicine ◽  
Diabetic Patients ◽  
Defined Daily Dose ◽  
Care Hospital ◽  
Utilization Pattern

<p><strong>Background</strong>: Diabetes mellitus is an emerging non communicable, life style disease. The aim was to evaluate the drug utilization pattern of anti-diabetic drugs in diabetic outpatients and monitor the adverse drug reactions (ADRs) associated with anti-diabetic therapy.</p><p><strong>Materials and</strong> <strong>methods</strong>: A prospective observational study was carried out in adult diabetic patients from the Department of General Medicine of a rural tertiary care hospital in October 2013- December 2014 after obtaining written informed consent from the patient and approval from institutional ethics committee. Demographic data, drug utilization pattern, cost of the antidiabetic drugs along with defined daily dose was calculated. ADRs due to anti-diabetic drugs were summarized.</p><p><strong>Results</strong>: A total of 450 patients were enrolled in the study of which there was male preponderance and majority belong to geriatric age. The most common comorbidity was hypertension. Insulin was most commonly prescribed drug during hospital stay and metformin at the time of discharge. Of the combination therapy dual therapy of metformin and glimipiride was most preferred. The total antihyperglycaemic drug consumption was 15.65 DDD/100 bed days. 67 ADR were reported of which the most common was hypoglycaemia.</p><p><strong>Conclusions</strong>: The study showed insulin and metformin were the most commonly used drugs. The prescribing trend also appears to be moving towards combination therapy particularly two drug therapies. The most commonly reported ADR was hypoglycaemia.</p>

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