scholarly journals A prospective study of efficacy and safety of mifepristone and vaginal misoprostol in termination of pregnancy up to 63 days of gestation

2017 ◽  
Vol 6 (2) ◽  
pp. 567
Author(s):  
Mahima Jain ◽  
Sonali Sharma
Keyword(s):  
Prospective Study ◽  
Tertiary Care ◽  
Common Adverse Effect ◽  
Reproductive Age ◽  
Illegal Abortion ◽  
Participation Motivation ◽  
Vaginal Misoprostol ◽  
A Prospective Study ◽  
Lost To Follow Up

Background: Illegal abortion is still one of the important causes of maternal mortality in India accounting for approximately 13%. Medical Management of abortion is a non-surgical termination which does not require special facilities like operation theatre, hospital stay and thereby reduces complications associated with the same.Methods: It is a prospective study done in a Tertiary care Government Hospital over a span from Jan 2015 to April 2016. After patient selection as per inclusion criteria and written informed consent after evaluating patients were enrolled in the study. In first visit Tab. mifepristone 200 mg. orally was given and advised to take Tab. misoprostol 800 mcg. Vaginally after 48 hours at home. They were counselled for side effects and asked to report in case of excess bleeding, pain, fever or no bleed for 24 hours of misoprostol. After 7 days follow up was done to ensure completion of abortion. Any additional drugs required were noted. Contraceptive advice is also given during these visits.Results: In our study 60 cases were taken. Majority of women are between 20-29 years of age which is peak reproductive age. 61.1% women are of second parity. The success rate of medical methods is 96.6%, two cases out of 60 underwent surgical evacuation and one was lost to follow up. Most common adverse effect noted is abdominal cramps. No patient required hospitalization. Additional Misoprostol was required in 4 cases. This method is highly acceptable 95% cases as it is non invasive and preferred to adopt the same in future if needed.Conclusions: Patient participation, motivation, compliance, regular follow up visits, ability to record and report complications are the pillars on which the success of medical methods depends. Hence overall, it came out to be safe and effective method.

scholarly journals Total Endoscopic Transcanal Cartilage Myringoplasty: A Prospective Study

2019 ◽  
Vol 23 (04) ◽  
pp. e440-e444
Author(s):  
Dipesh Shakya ◽  
Arun KC ◽  
Ajit Nepal ◽  
Nirmala Tamang
Keyword(s):  
Prospective Study ◽  
Chronic Otitis Media ◽  
Endoscopic Approach ◽  
Closure Rate ◽  
Hearing Results ◽  
A Prospective Study ◽  
Lost To Follow Up ◽  
Air Conduction ◽  
Hearing Evaluation

Introduction Middle ear surgeries, including myringoplasty, have increasingly utilized endoscopes as an adjunct to or as a replacement for the operative microscope. Objectives The objective of the present study was to evaluate the graft uptake rate and to evaluate the hearing results. Methods This is a prospective study. We have analyzed 139 patients who underwent surgery for chronic otitis media (COM) of the mucosal type. All of the surgeries were performed exclusively under total endoscopic transcanal approach using tragal cartilage as graft, underlay technique. We have evaluated the postoperative graft uptake and performed a hearing evaluation at 6 weeks, at 12 weeks, and at 6 months. Results During the study period, 139 patients were included, out of which 13 were lost to follow-up; therefore, only 126 patients were assessed. All of the cases were performed under total endoscopic approach. As for the surgical outcome at the postoperative otoscopy, 3 cases had initial uptake at 3 months and failed later; therefore, complete closure of the perforation was observed in 97.6% (n = 123) of the patients 6 months after the intervention.Four patients presented with preoperative anacusis; therefore, only 122 patients were included for hearing evaluation. The preoperative air conduction threshold (ACT) and airbone gap (ABG) were 43.34 ± 11.53 and 24.73 ± 7.89, respectively.Postoperatively, the ACT and ABG closure were 28.73 ± 15.75 and 11.91 ± 8.41, respectively. This difference was statistically significant (p < 0.001). Conclusion The endoscopic approach for myringoplasty offers excellent visualization; avoids postaural approach, enables a faster recovery, requires less hospital stay, with excellent graft closure rate and improved functional outcomes.

The management of quinsy—a prospective study

1992 ◽  
Vol 106 (11) ◽  
pp. 986-988 ◽  
Author(s):  
C. R. Chowdhury ◽  
M. C. M. Bricknell
Keyword(s):  
Prospective Study ◽  
Significant Saving ◽  
Incision And Drainage ◽  
The Social ◽  
Student’S T ◽  
A Prospective Study ◽  
Abscess Tonsillectomy ◽  
Lost To Follow Up ◽  
Student’S T Test

AbstractA prospective study for the treatment of quinsy was undertaken between January 1989 and September 1991. This was to determine whether abscess tonsillectomy reduces inpatient stay without increasing operative risk compared to incision and drainage combined with interval tonsillectomy. Fifty-three patients were entered into the study. Twenty-one had abscess tonsillectomy and 32 had incision and drainage. This study showed that there is a 95 per cent probability that abscess tonsillectomy reduces hospital stay by between 2.04 and 4.84 (Student's t test t = 5.01; df = 31, p<0.001) days compared to incision and drainage followed by interval tonsillectomy. This is a significant saving in time and resources. Abscess tonsillectomy reduces patients lost to follow-up, avoids the social inconvenience of a second admission, effectively relieves symptoms, treats a contralateral abscess and is the only method of treating children with a quinsy. We recommend abscess tonsillectomy should be performed for quinsy where expertise and facilities are available.

scholarly journals Efficacy and Safety of Diphenylcyclopropenone in the Treatment of Multiple Warts - A Prospective Study at a Tertiary Care Hospital, Mumbai

2021 ◽  
Vol 8 (20) ◽  
pp. 1580-1585
Author(s):  
Prathyusha Yakkala ◽  
Rachita Dhurat ◽  
Meghana Phiske
Keyword(s):  
Prospective Study ◽  
Tertiary Care ◽  
Care Hospital ◽  
Efficacy And Safety ◽  
Viral Origin ◽  
Factors Affecting ◽  
Type Iv ◽  
Significant Difference ◽  
A Prospective Study

BACKGROUND Diphenylcyclopropenone (DPCP) produces type IV hypersensitivity reaction, immune response being directed against a complex of contact agent hapten bound to proteins of viral origin that enhance wart regression. We wanted to evaluate the efficacy and safety of DPCP in multiple warts along with the various factors affecting DPCP response METHODS A prospective study with 49 patients older than 5 years with 5 or more warts in any area (except genital) was conducted. Patients were sensitized with 2 % DPCP solution and examined after 48 hours. Sensitization was graded as mild, moderate, severe or no sensitization. Patients with mild / moderate sensitization were further applied DPCP; patients with severe sensitization were included after subsidence of reaction and patients with no sensitization were excluded. After sensitization, weekly applications were made on warts. Concentration causing mild reaction was selected as optimal and was applied till lesion clearance. Follow up was for 3 months for recurrences. Response was graded as complete, partial and no response. RESULTS Males outnumbered females. Mean age was 23 years. Mean duration was 12 months. Recurrent and resistant warts were seen in 15 and 6 patients respectively. Mean number of warts was 15.6. 49 patients were tested for sensitization, 1 failed sensitization and 48 were continued with weekly DPCP. 2 developed distant eczematisation and 4 were lost to follow up. Out of 42, complete clearance was seen in 35 (83.3 %), partial in 3 (7.14 %) and no response in 4 (9.52 %). Local eczematisation, lymphadenopathy, hyperpigmentation were the side effects. Response was better with increasing age. Warts less than 6 months had 100 % response. There was no statistically significant difference between site and type of warts and response to DPCP, recurrent and untreated warts in terms of response and response to sensitization and final response. CONCLUSIONS DPCP is an excellent option for multiple / resistant warts with good safety profile. KEYWORDS Diphenylcyclopropenone, Multiple Warts, Safety, Efficacy, Various Factors Affecting Response

scholarly journals CORRELATION BETWEEN ULTRASOUND-BASED ACR TI-RADS AND BETHESDA SYSTEM FOR REPORTING THYROID-CYTOPATHOLOGY: A PROSPECTIVE STUDY AT TERTIARY CARE CENTER IN EASTERN INDIA

2020 ◽  
pp. 1-4
Author(s):  
Kapse Pratik Siddheshwar ◽  
Beena Devi Agarwal ◽  
S. S. G. Mohapatra ◽  
Niranjan Sahu ◽  
Apoorva Dixit
Keyword(s):  
Prospective Study ◽  
Thyroid Nodules ◽  
Care Center ◽  
Tertiary Care ◽  
Imaging Tool ◽  
Risk Of Malignancy ◽  
Initial Imaging ◽  
A Prospective Study ◽  
Risk Of Cancer

BACKGROUND: Ultrasound(USG) is the initial imaging tool for the assessment of thyroid lesions, due to its easy availability and no radiation risk.USG based TIRADS uses particular lexicons for reporting a focal thyroid nodule,based on which risk of malignancy is calculated and finally a TIRADS category is assigned.The lexicons used are helpful for effective communication between the practitioners. OBJECTIVE:To determine the efficacy of ACR based TIRADS in predicting suspicious thyroid nodules and categorizing the patients in need of further evaluation with FNAC or follow up. MATERIALS AND METHODS: This prospective study was done over a period of 1 year (January 2019–January 2020)and include 50 patients. Patients having thyroid nodules in B-mode ultrasound were included in the study. The nodules were then grouped into their respective categories based on ACR TI-RADS and further management was decided. Pathological correlation using Bethesda classification and cancer risk of each TIRADS category was determined in the follow-up period simultaneously. RESULTS:All the 6 nodules classified under the TIRADS 5 category were found to be malignant while none of the TIRADS 2 nodules out of 29 were malignant i.e.Bethesda IV or higher.The risk of malignancy for ACR TI-RADS categories 1,2,3,4 and 5 was 0, 14.3, 62.5 and 100%, respectively.The risk of cancer in our study is almost comparable to other prominent studies. CONCLUSION:ACR based TIRADS classification is reliable in predicting thyroid malignancy.

scholarly journals A prospective study to evaluate safety, efficacy and expulsion rate of post-partum insertion of intrauterine contraceptive device in a tertiary care centre

2017 ◽  
Vol 6 (3) ◽  
pp. 814
Author(s):  
Sudha R. ◽  
Nikita Singh
Keyword(s):  
Developing Countries ◽  
Prospective Study ◽  
Retention Rate ◽  
Post Partum ◽  
Public Awareness ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Contraceptive Device ◽  
Widespread Application

Background: The concept of contraception is not new, but its widespread application definitely is. Contraceptive availability is paramount for the health of women of reproductive age group. Among the variety of options available, female sterilization and IUCD are the most popular in developing countries. This study was conducted to assess the safety, incidence of complications, expulsion rates and willingness to continue at a 6 weeks’ follow-up period; after insertion of Cu T 380 A within ten minutes of placental expulsion both in vaginal and C-section deliveries.Methods: Prospective study in the Department of Obstetrics and Gynaecology, Cheluvamba Hospital from a period of 1st January 2016 to 31st June 2016. All consenting antenatal cases including referrals, who fulfil all the inclusion criteria were included in the study. Expulsion rates at 6 weeks’ follow-up were measured.Results: Total women counselled were 462, accepted 50, declined 412, lost to follow up 3, followed up 47, expulsion 3, bleeding 11, string problems 5, removal 8, continuation 36.Conclusions: PPIUCD is demonstrably a safe and effective contraceptive with high retention rate in the hands of a skilled caregiver. Strategies to increase public awareness through media sources are the need of the hour. Training of healthcare providers, cash incentives to acceptor, motivator and provider would further promote its use in developing countries like India.

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