scholarly journals Clinical study of hypo/hyper thyroidism in dysfunctional uterine bleeding

Author(s):  
Usharani N. ◽  
Kaveri Shavi

Background: Dysfunctional uterine bleeding is one of the most frequently encountered condition in gynaecological practice. Thyroid hormones play a key role in the menstrual and reproductive function of women and thus thyroid dysfunction results in menstrual disturbances. The objective is to study the prevalence of thyroid disorders in patients with dysfunctional uterine bleeding.Methods: This is a hospital based prospective observational study done in the department of Obstetrics and Gynaecology, Vijayanagara Institute of Medical Sciences, Ballari. The study period is from February 2016 to August 2016. In the study, 100 patients with dysfunctional uterine bleeding were included and evaluated for thyroid abnormality.Results: Among 100 patients with DUB, thyroid disorders were prevalent in 24 % of patients. Hypothyroidism was present in 22% and hyperthyroidism in 2% of the women with DUB. The commonest menstrual complaint associated with hypothyroidism was menorrhagia, seen in 54.54% of cases. In 2 patients with hyperthyroidism one each had menorrhagia and metropathia haemorrhagica.Conclusions: Thyroid dysfunction is one of the important cause for DUB. Hypothyroidism is more commonly associated with DUB than hyperthyroidism. Evaluation of thyroid status is important in all patients with DUB to avoid unnecessary surgical interventions.

2016 ◽  
Vol 6 (12) ◽  
pp. 1018-1020
Author(s):  
S Subedi ◽  
B Banerjee ◽  
C Manisha

Background: Thyroid hormones play a key role in the menstrual and reproductive function of women .It is recognized universally that menstrual disturbances may accompany clinical alteration in thyroid function and every clinician has encountered altered menstrual pattern among women suffering from thyroid disorders. The aim of this study was to find the incidence of thyroid disorders in Dysfunctional uterine bleeding and its correlation with menstrual patterns.Materials and Methods: A hospital based cross-sectional study including 75 cases with dysfunctional uterine bleeding attending the OPD of Nobel Medical College, where incidence of thyroid disorder was evaluated along with its correlation with menstrual patterns and histopathology.Results: The incidence of Gynecological OPD attendance due to abnormal uterine bleeding was 3%.and the incidence of thyroid dysfunction was 10.6% with hypothyroidism being the commonest. (9.3%). The commonest menstrual pattern found was menorrhagia/polymenorrhoea in 8 percent.Conclusion: Prevalence of hypothyroidism was more common in DUB. Thus every woman with menstrual irregularities should undergo thyroid assessment and this will ultimately avoid unnecessary intervention like misuse of hormonal treatment and hysterectomy.


2021 ◽  
pp. 15-16
Author(s):  
Kumari Ragini ◽  
Kumar Sourav ◽  
Lata Shukla Diwedi ◽  
Debarshi Jana

Introduction: Abnormal uterine bleeding (AUB) is a common disorder occurring in reproductive age group females. It can be understood as bleeding that occurs from the uterus outside the normal parameters and there is no structural defects in the genital tract. One of the most common association with AUB is thyroid dysfunctions. Hence this study aimed to see the incidence of thyroid related disorders in AUB and also to assess the menstrual pattern. Material and Methods: 100 women suffering from AUB who presented to OPD of Obstetrics and Gynecology department of Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar were recruited in the study. All females in 19 to 45 years of age group with abnormal uterine bleeding were included excluding those with previously known thyroid disorder, abortion history within 3 months etc. Thyroid function tests were done in all along with ultrasonography of pelvis region. Statistical analysis done. Results: The bleeding abnormality that was found in the most of the women was heavy menstrual bleeding. Women who presented with thyroid dysfunction were 33%. 23% had subclinical hypothyroidism, 6% had hypothyroidism and 4% had hyperthyroidism. Conclusion: Abnormal Uterine Bleeding has strong association with thyroid disorders. Most common type of disorder is subclinical hypothyroidism. Thus all patient of AUB must be evaluated for thyroid dysfunction


2014 ◽  
Vol 4 (8) ◽  
pp. 635-638
Author(s):  
N Katuwal ◽  
G Gurung ◽  
A Rana ◽  
A Jha

Background: Dysfunctional uterine bleeding is a form of abnormal uterine bleeding when there is absence of organic disease of the genital tract. The objective of this study was to find out the clinical and pathological aspect of women presenting with dysfunctional uterine bleeding.Materials and Methods: A descriptive study was conducted over a period of one year from April 14th 2010 to April 13th 2011 in the Department of Obstetrics and Gynaecology and Department of Pathology, Tribhuvan University Teaching Hospital, Kathmandu, Nepal. A complete history, clinical examination, pelvic scan, hormonal status if required and endometrial biopsy were done to diagnose dysfunctional uterine bleeding.Results: A total of 120 cases were included. The age of the patients diagnosed dysfunctional uterine bleeding were ranging from 24 -63 years. Dysfunctional uterine bleeding was most common in the age group 40-44 yrs (30%) followed by 45-49 yrs (27.5%). Menorrhagia (41.7%) was the most common presenting sign. Majority histopathology of endometrium revealed anovulatory pattern (61.7%) followed by ovulatory (38.3%). Of the cases with an anovulatory pattern 48.6% was proliferative endometrium, 33.8% disordered proliferative endometrium, 6.8%atrophic, 5.4% weakly proliferative and 2.7% each of simple hyperplasia without atypia and complex hyperplasia with atypia. All cases with ovulatory pattern showed secretory endometrium.Conclusion: Dysfunctional uterine bleeding was the most common in the perimenopausal age group and chiefly in the form of an anovulatory endometrium. . Histopathological evaluation of endometrium helps exclude the local causes and establishes the diagnosis of dysfunctional uterine bleeding, its types, and clinical correlation to histopathological findings and finally helps to determine the mode of management.DOI: http://dx.doi.org/10.3126/jpn.v4i8.11500 Journal of Pathology of Nepal; Vol.4,No. 8 (2014) 635-638


Author(s):  
Aditi Rai ◽  
Sapna Raina

Background: Abnormal uterine bleeding (AUB) is one of the most frequent presentation to gynecology OPD. AUB is a common but complicated clinical presentation and occurs in 15-20% of women between menarche to menopause and significantly affects the women’s health. Thyroid disorders are more common in women than in men and cause abnormal sexual development, menstrual irregularity, infertility and premature menopause. Objective of this study was to estimate the prevalence of thyroid disorders in women in reproductive age group with AUB.Methods: A hospital based prospective cross sectional observational study was carried out in department of obstetrics and gynecology, Mazumdar-Shaw Cancer and Medical Center and Narayana Hrudayalaya Hospital at Narayana Health City, Bangalore with abnormal uterine bleeding during the period of 2 years (December 2015 to November 2017), total 153 patients were included in the study. All women with AUB in reproductive age group were included. Diagnosed cases of ovarian cyst, uterine fibroid, polyp, adenomyosis, endometriosis and malignant (endometrial and cervical) tumors were excluded. Women who are on drugs or hormone therapy (for past 3 months. IUCD users/oral contraceptives pill user. Patients with known case of thyroid disorder, carcinoma thyroid patients with history of coagulation disorder, liver disorder, renal disorder, tuberculosis.Results: A total N=115 (75.2%) of patients who took part in this study had euthyroid status. The estimated prevalence of thyroid dysfunction was 24.9%. Out of which n=22 (14.4%) had subclinical hypothyroidism, n=14 (9.2%) had overt hypothyroidism, n=2 (1.3%) had hyperthyroidism. The most common thyroid dysfunction amongst the study group was noted to be subclinical hypothyroidism (14.4%).Conclusions: There is a high prevalence of thyroid disorders in cases which are clinically diagnosed as AUB. TSH is most sensitive test in detecting thyroid dysfunction. Subclinical cases need to be treated. Hence thyroid function evaluation should be made mandatory in cases of AUB to detect thyroid dysfunction.


Author(s):  
Koduru Mounika

Aim: The purpose of the study was to detect thyroid dysfunction in women who had abnormal uterine bleeding Study Design: Menorrhagia was the most common type of bleeding (36%). Thyroid dysfunction was discovered in 32% of the patients (Subclinical hypothyroidism in 17%, Hyper thyroid is 11% and hyperthyroidism in 4 % of cases). The researchers looked at 100 cases of Dysfunctional Uterine Bleeding that were clinically identified at Sree Balaji Medical College and Hospital between March 2014 and August 2016. The patients in this study ranged in age from under 20 to 45 years old. The number of instances with DUB who were between the ages of 31 and 40 is 38 %. Methodology: The parity of the patients ranged from unmarried to 0-5, with the parity 2 group accounting for 37% of all DUB patients and the following assessments were made. Results: Thyroid dysfunction was most common in cases of polymenorrhagia (42.8%), menorrhagia (33.3%), polymenorrhea (28.5%), and oligomenorrhea. (26%). Thyroid dysfunction was most common in the age group 31-40 years, accounting for 77.5% of the population. In 17 % of cases, the primary thyroid malfunction was subclinical hypothyroidism. 3% of hyperthyroid patients were also oligomenorrhocic. The most prevalent thyroid disorder in metrorrhagic patients was subclinical hypothyroidism.


Author(s):  
Ashok Kumar H. S. ◽  
Saravanan S. ◽  
Saravanan S.

Background: Thyroid gland is the most vital endocrine organ which plays a major role in growth, development, metabolism and function of almost every organ of our body. Both hypothyroidism and hyperthyroidism can result in menstrual irregularities. Abnormal Uterine Bleeding (AUB) is one of the most common, yet complicated clinical presentation. It occurs in 10-20% of women between 15-50 years of age. Timely detection of thyroid dysfunction in patients presenting with AUB and their proper management can prevent unnecessary surgical interventions. This study was done to analyze the prevalence of thyroid dysfunction in patients with AUB and also to look for different menstrual patterns associated with thyroid dysfunction.Methods: This is a prospective study conducted at Department of Obstetrics and Gynecology, Government Medical College, Manjeri, Kerala, India. Total 200 patients were recruited into present study after satisfying all inclusion and exclusion criteria. Complete history was taken followed by a thorough examination. Baseline investigations and T3, T4, TSH was performed in all patients. Results were analyzed.Results: As per present study, majority of the patients with AUB were from the age group of 35-49 years (43%). In patients with AUB with thyroid dysfunction, prevalence of subclinical hypothyroidism was most common followed by hypothyroidism. According to our study thyroid dysfunction was most commonly seen in the age group of 35-49 years, and the most common presentation being menorrhagia.Conclusions: Timely diagnosis and proper management of thyroid dysfunction in women with AUB can avoid variety of non-specific and ineffective diagnostic and therapeutic procedures.


Author(s):  
Bhagyashree Bijjaragi ◽  
Amulya M. N.

Background: If laparotomy done within 60 days of primary surgery for the original disease it is called re-laparotomy. Aim of this study was to determine the risk factors causing re-laparotomy, the indications, management and outcomes of re-laparotomy.Methods: The study was conducted in the department of Obstetrics and Gynaecology, Vijayanagar Institute of Medical Sciences Hospital, Bellary, Karnataka. It is a 2 year prospective observational study of all the patients with re-laparotomy following operation done for obstetric or gynaecological indications.Results: Total 4105 patients underwent major surgery in two years between October 2013 to September 2015. Re-laparotomy was done in 10 cases. The incidence of re-laparotomy was 0.25% which is mainly for subacute intestinal obstruction, intraperitoneal haemorrhage, burst abdomen, PPH, rectus sheath hematoma.Conclusions: Hemorrhage, burst abdomen, infections are the main reasons for re-laparotomy after obstetric and gynaecological surgeries. Though the incidence of re-laparotomy is low and the outcome is favourable, several measures must be undertaken to prevent re-laparotomy such as careful surgical technique, meticulous hemostasis and strict asepsis should be maintained.


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