scholarly journals A study of dengue fever in pregnancy and its maternal and fetal prognosis

Author(s):  
Hanslata Gehlot ◽  
Om Prakash Yadav ◽  
Seema Sharma ◽  
Girdhar Gopal Nagar ◽  
Ayna Yadav ◽  
...  

Background: Dengue is a vector borne viral disease. Female Anopheles mosquito is the vector for the disease. Recently, there is an increase in the incidence of dengue fever in adult population in South Asian countries. With increasing rate of adult dengue fever victims, the number of infected pregnant women has also been increased. Dengue, during pregnancy may be associated with various complications, including abortions, preterm delivery, maternal mortality, low birth weight, neonatal admissions and fetal anomalies. Timely intervention can improve the maternal as well as fetal outcome. This study was aimed to assess the clinical profile, maternal and fetal outcome of dengue fever during pregnancy.Methods: The study was carried out on 25 pregnant females diagnosed and serologically confirmed to have dengue fever and were admitted in Umaid hospital, associated to Dr. S. N. Medical College Jodhpur, Rajasthan, India. Patients were included irrespective of the period of gestation of contracting the disease. Serological testing for dengue virus specific antigen and antibody was done for the diagnosis of dengue fever. The World Health Organization (WHO) classification and case definitions 2009 were used to categorize the dengue patients. A predesigned proforma was used to collect data related to maternal and fetal consequences both during pregnancy and at birth, as well as the effect on the newborn. Informed and written consent was taken from all those who participated in the study.Results: Thrombocytopenia (platelet count <1.5lakh/mm3) was found in 22 (88%) patients out of which 6 (24%) of them had platelet count below 20,000 cells/mm3 and 3(12%) patients required platelet transfusion. Other complications observed were spontaneous abortions (4%); preterm birth (16%), oligohydramnios (8%) and antepartum hemorrhage (4%). One patient was admitted to Intensive Care Unit. Fetal distress and meconium stained amniotic fluid was observed in 16% and 12% patients respectively. Adverse fetal outcome was observed in form of low birth weight, prematurity. 8% of the babies required NICU admission and 4% were Intra Uterine Fetal Death (IUFD).Conclusions: Maternal infection with the dengue virus during antenatal period represents a real risk of premature birth. Early onset or late onset in pregnancy appeared to have a bad prognosis.  A high index of clinical suspicion is essential in any pregnant woman with fever during the epidemic. The treatment of dengue in pregnancy is mainly conservative as in non-pregnant adults. In case of high risk cases early referral to well-equipped health centres where technical, transfusion and intensive care facilities are available may prove lifesaving.

2020 ◽  
Vol 5 (3) ◽  
pp. 1201-1205
Author(s):  
Vibha Mahato ◽  
Pravin Shrestha

Introduction: Anemia is one of the most common disorders affecting the pregnant women in the developing countries like Nepal. Anemia during pregnancy is commonly associated with adverse pregnancy outcomes. Identifying anemia in pregnancy and knowing its common complications will help improve maternal quality care. Objectives: The objective - was to  assess the effects of anemia on pregnancy outcome at Manipal Teaching Hospital Methodology: This cross sectional study was conducted in Manipal Teaching Hospital from September 2019 to April 2020. A total of 200 anemic pregnantladies  attending obstetrics Out Patient Department were selected.Hemoglobinlevel was taken as criteria for deciding anemia and  to classify  severity of anemia.Anemia in pregnancy is defined by World Health Organization as hemoglobin level less than 11 gm/dl, and hemoglobin concentration of 10–10.9 g/dl, 7–9.9 g/dl, and <7 g/ dl was considered as mild, moderate, and severe anemia, respectively . All were treated depending on severity of anemia and followed up for maternal and perinatal outcome.Data was collected in Microsoft Excel and analyzed by using SPSS version 16. Result: We found moderate anemia in 129 (64.5%) cases followed by mild in 61(30.5%) and severe in 10(5%) cases. Common maternal complications in anemic patients werepremature rupture of membranein 30 (15%) cases and Urinary Tract Infection in 30(15%) cases.During puerperiumPostpartum Hemorrhage was observed in 12(6%) and wound infection in 9 (4.5%) cases of anemic patient. High incidence of adverse fetal outcome in the form of preterm in 39 (19.5%), Intrauterine growth restrictionin 23(11.5%), Intensive Care Unitadmission in28(14%),low birth weight in41(20.5%) and Intrauterine Death in4(2%) cases of anemic patients were seen. Conclusion: Maternal infection and adverse perinatal outcome in form of intrauterine growth restriction, Intensive Care Unitadmission, low birth weight and perinatal death were significantly associated with anemia in pregnancy.


2013 ◽  
Vol 8 (1) ◽  
pp. 37-40
Author(s):  
Sadikchya Singh Rana ◽  
S Sharma ◽  
A Chand ◽  
R Malla

Aims: This study was done to determine the relationship between maternal haemoglobin and fetal weight. Methods: This study was carried out at Paropakar Maternity and Women’s Hospital in 491 primigravidas with full term singleton pregnancy. The study population was divided into two groups, one who had haemoglobin 10 gm% or more and the other women having haemoglobin less than 10 gm%. Fetal weight as the outcome variable was compared between anaemic and nonanaemic mothers and the relation between maternal haemoglobin and fetal weight was studied. Results: The prevalence of anaemia was 46.2% out of which 99.5% had mild anaemia and 0.5% had moderate anaemia. Mean haemoglobin level was 11.54 gm% among non anaemic women and mean birth weight was 2.9 kg in this group whereas mean haemoglobin level was 9.2 gm% in anaemic women and mean birth weight was 2.6 kg in this group and 60% babies had low birth weight (<2.5 kg) born to anaemic women (haemoglobin <10 gm%), and 40% babies had fetal weight >2.5 kg. Similarly babies born to nonanaemic women (haemoglobin >10 gm%) 18.1% had LBW and 81.9% had fetal weight >2.5 kg. The risk of low birth weight was 6.8 times higher among anaemic mothers as compared to non- anaemic mothers which was statistically significant with p-value of 0.0001 (OR 6.80 95% CI, 3.83-12.12). Conclusions: Anemia in pregnancy is one of the causes for poor fetal outcome. Proper antenatal care and counseling can reduce the incidence of anaemia in pregnancy. Nepal Journal of Obstetrics and Gynaecology / Vol 8 / No. 1 / Issue 15 / Jan- June, 2013 / 37-40 DOI: http://dx.doi.org/10.3126/njog.v8i1.8860


Author(s):  
Anjar Fifi Wulandari ◽  
Emi Sutrisminah ◽  
Is Susiloningtyas

In general, the most common cause of anaemia in pregnancy is iron deficiency, which arises from maternal-fetal iron transfer, which is often exacerbated by a decrease in maternal iron stores. According to the World Health Organization (WHO), pregnancy anaemia is a global health problem that affects almost half of pregnant women. The purpose of this study was to conduct a journal review of explanatory and experimental articles published in the last 5 years starting in 2016 on deficiency anaemia in pregnancy. The research method is carried out by literature study using an electronic reference library through Medline, PubMed, NCBI, Science Direct and Proquest by investigating the impact of anaemia in pregnant women. The results literature from research in various developing and developed countries show that there is an impact that occurs when the mother had anaemia during pregnancy, namely prematurity, low birth weight, postpartum hemorrhage, maternal mortality, cesarean delivery and mental development of children. The conclusion is that there are several effects of anaemia in pregnant women, which are prematurity, low birth weight, postpartum hemorrhage, maternal mortality, cesarean delivery and children's mental development.


2017 ◽  
Vol 33 (3) ◽  
pp. 524-532 ◽  
Author(s):  
Elizabeth B. Froh ◽  
Janet A. Deatrick ◽  
Martha A. Q. Curley ◽  
Diane L. Spatz

Background: Very little is known about the breastfeeding experience of mothers of infants born with congenital anomalies and cared for in the neonatal intensive care unit (NICU). Often, studies related to breastfeeding and lactation in the NICU setting are focused on the mothers of late preterm, preterm, low-birth-weight, and very-low-birth-weight infants. Congenital diaphragmatic hernia (CDH) is an anatomic malformation of the diaphragm and affects 1 in every 2,000 to 4,000 live births. Currently, there are no studies examining the health outcomes of infants with CDH and the effect of human milk. Research aim: This study aimed to describe the breastfeeding experience of mothers of infants with CDH cared for in the NICU. Methods: A prospective, longitudinal qualitative descriptive design was used. Phased interviews were conducted with a purposive sample of 11 CDH infant–mother dyads from a level 3 NICU in a children’s hospital. Results: Six themes emerged from the data: (a) hopeful for breastfeeding, (b) latching on . . . to the pump, (c) we’ve already worked so hard, (d) getting the hang of it—it’s getting easier, (e) a good safety net, and (f) finding a way that works for us. Conclusion: For this population of CDH infant–mother dyads, the term breastfeeding is not exclusive to direct feeding at the breast and the mothers emphasized the significance of providing their own mother’s milk through a combination of feeding mechanisms to their infants with CDH.


2016 ◽  
Vol 61 (1) ◽  
pp. 90-95 ◽  
Author(s):  
Jadwiga Wójkowska-Mach ◽  
T. Allen Merritt ◽  
Maria Borszewska-Kornacka ◽  
Joanna Domańska ◽  
Ewa Gulczyńska ◽  
...  

PEDIATRICS ◽  
1992 ◽  
Vol 89 (2) ◽  
pp. 357-357
Author(s):  
WILLIAM TARNOW-MORDI ◽  
ANDREW WILKINSON

To the Editor.— In their valuable report1 Dr Hack and colleagues confirm large variations between centers in the perinatal histories, treatment, and outcomes of very low birth weight infants. Unfortunately, in contrast to earlier reports,2,3 they neglect to mention the need for measures of initial disease severity. This is an important omission. In a survey of nine pediatric intensive care centers Pollack et al4 showed that hospital mortality varied from 3.6% to 17%. This large variation was explained completely by differences between hospital populations in initial severity of disease, calculated from routine indices of physiologic stability on the day of admission.


2021 ◽  
pp. 91-93
Author(s):  
Srinisha Soundararaja ◽  
Meghna Treesa Anton ◽  
K. Saraswath

Dengue is a vector-borne viral disease. It is a disease caused by any one of the four closely related viruses (DEN-1, DEN-2, DEN-3, or DEN-4). The viruses are transmitted to humans by the bite of an infected mosquito (Aedes aegypti). Recently, there is an increase in the incidence of dengue fever in adult population in South Asian countries. With an increasing rate of adult dengue fever victims, the number of pregnant women infected with dengue has also increased. Dengue, during pregnancy may be associated with various complications, including abortions, preterm delivery, maternal mortality, low birth weight, neonatal admissions, and fetal anomalies. Timely intervention can improve the maternal as well as fetal outcome. This study was aimed to assess the clinical prole, maternal and fetal outcome of dengue fever during pregnancy and post-delivery. This study shows various outcomes in different trimesters of pregnanc


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