scholarly journals LITERATURE REVIEW: DAMPAK ANEMIA DEFISIENSI BESI PADA IBU HAMIL

2021 ◽  
Vol 16 (3) ◽  
pp. 892-898
Author(s):  
Anjar Fifi Wulandari ◽  
Emi Sutrisminah ◽  
Is Susiloningtyas
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Maternal Mortality ◽  
Pregnant Women ◽  
Cesarean Delivery ◽  
Postpartum Hemorrhage ◽  
Mental Development ◽  
World Health ◽  
Anaemia In Pregnancy ◽  
In Pregnancy

In general, the most common cause of anaemia in pregnancy is iron deficiency, which arises from maternal-fetal iron transfer, which is often exacerbated by a decrease in maternal iron stores. According to the World Health Organization (WHO), pregnancy anaemia is a global health problem that affects almost half of pregnant women. The purpose of this study was to conduct a journal review of explanatory and experimental articles published in the last 5 years starting in 2016 on deficiency anaemia in pregnancy. The research method is carried out by literature study using an electronic reference library through Medline, PubMed, NCBI, Science Direct and Proquest by investigating the impact of anaemia in pregnant women. The results literature from research in various developing and developed countries show that there is an impact that occurs when the mother had anaemia during pregnancy, namely prematurity, low birth weight, postpartum hemorrhage, maternal mortality, cesarean delivery and mental development of children. The conclusion is that there are several effects of anaemia in pregnant women, which are prematurity, low birth weight, postpartum hemorrhage, maternal mortality, cesarean delivery and children's mental development.

Quantifying Pregnant Women’s Knowledge of Educational Components of Antenatal Care in Lesotho

2019 ◽  
Vol 21 (1) ◽  
Author(s):  
Tabeta Seeiso ◽  
Mamutle M. Todd-Maja
Keyword(s):  
Antenatal Care ◽  
Maternal Mortality ◽  
Pregnant Women ◽  
Rural Areas ◽  
Geographic Location ◽  
Sub Saharan Africa ◽  
World Health ◽  
Cross Sectional ◽  
Danger Signs ◽  
In Pregnancy

Antenatal care (ANC) literacy is particularly important for pregnant women who need to make appropriate decisions for care during their pregnancy and childbirth. The link between inadequate health literacy on the educational components of ANC and maternal mortality in sub-Saharan Africa (SSA) is undisputable. Yet, little is known about the ANC literacy of pregnant women in SSA, with most studies inadequately assessing the four critical components of ANC literacy recommended by the World Health Organization, namely danger signs in pregnancy; true signs of labour; nutrition; and preparedness for childbirth. Lesotho, a country with one of the highest maternal mortality rates in SSA, is also underexplored in this research area. This cross-sectional study explored the levels of ANC literacy and the associated factors in 451 purposively sampled women in two districts in Lesotho using a structured questionnaire, making recourse to statistical principles. Overall, 16.4 per cent of the participants had grossly inadequate ANC literacy, while 79.8 per cent had marginal levels of such knowledge. The geographic location and level of education were the most significant predictors of ANC literacy, with the latter variable further subjected to post hoc margins test with the Bonferroni correction. The participants had the lowest scores on knowledge of danger signs in pregnancy and true signs of labour. Adequate ANC literacy is critical to reducing maternal mortality in Lesotho. Improving access to ANC education, particularly in rural areas, is recommended. This study also provides important recommendations critical to informing the national midwifery curriculum.

scholarly journals Effects of anemia on pregnancy outcomes at Manipal Teaching Hospital

2020 ◽  
Vol 5 (3) ◽  
pp. 1201-1205
Author(s):  
Vibha Mahato ◽  
Pravin Shrestha
Keyword(s):  
Intensive Care ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Teaching Hospital ◽  
Pregnancy Outcomes ◽  
World Health ◽  
Intrauterine Death ◽  
Intrauterine Growth ◽  
Anemia In Pregnancy ◽  
In Pregnancy

Introduction: Anemia is one of the most common disorders affecting the pregnant women in the developing countries like Nepal. Anemia during pregnancy is commonly associated with adverse pregnancy outcomes. Identifying anemia in pregnancy and knowing its common complications will help improve maternal quality care. Objectives: The objective - was to  assess the effects of anemia on pregnancy outcome at Manipal Teaching Hospital Methodology: This cross sectional study was conducted in Manipal Teaching Hospital from September 2019 to April 2020. A total of 200 anemic pregnantladies  attending obstetrics Out Patient Department were selected.Hemoglobinlevel was taken as criteria for deciding anemia and  to classify  severity of anemia.Anemia in pregnancy is defined by World Health Organization as hemoglobin level less than 11 gm/dl, and hemoglobin concentration of 10–10.9 g/dl, 7–9.9 g/dl, and <7 g/ dl was considered as mild, moderate, and severe anemia, respectively . All were treated depending on severity of anemia and followed up for maternal and perinatal outcome.Data was collected in Microsoft Excel and analyzed by using SPSS version 16. Result: We found moderate anemia in 129 (64.5%) cases followed by mild in 61(30.5%) and severe in 10(5%) cases. Common maternal complications in anemic patients werepremature rupture of membranein 30 (15%) cases and Urinary Tract Infection in 30(15%) cases.During puerperiumPostpartum Hemorrhage was observed in 12(6%) and wound infection in 9 (4.5%) cases of anemic patient. High incidence of adverse fetal outcome in the form of preterm in 39 (19.5%), Intrauterine growth restrictionin 23(11.5%), Intensive Care Unitadmission in28(14%),low birth weight in41(20.5%) and Intrauterine Death in4(2%) cases of anemic patients were seen. Conclusion: Maternal infection and adverse perinatal outcome in form of intrauterine growth restriction, Intensive Care Unitadmission, low birth weight and perinatal death were significantly associated with anemia in pregnancy.

scholarly journals Anemia and Low Birth Weight Risk After Fe Therapy in Pregnancy, Puskesmas Kecamatan Kebayoran Baru

2021 ◽  
Vol 9 (1) ◽  
pp. 109-115
Author(s):  
Dyah Ponco Sudarmaningsih ◽  
◽  
Febrial Hikmah ◽  
N Sri Widada ◽  
Rustiana Tasya Ariningpraja
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Physiological Changes ◽  
Cross Sectional ◽  
Before And After ◽  
In Pregnancy

Physiological changes in pregnant women have an impact on reducing the hemoglobin (Hb) level so that they can experience anemia. Anemia in pregnant women is still a high case and be one of the factors of low birth weight (LBW). Iron (Fe) is consumed routinely is thought to help reduce the risk of anemia, but it's still not known yet between the relation of Fe consumed to LBW incidents. Data were taken by cross sectional as many as 150 samples of pregnant women. The results obtained that 56% of pregnant women had anemia. After Fe therapy doses 60-120 mg/day, Hb levels increased by 0.3 g/dL. Although there were significant differences before and after Fe therapy in pregnant women with anemia, about 74% of pregnant women still had experience anemia despite Fe therapy. Provision of Fe therapy for pregnant women either with a dose of 60-120 mg/day, had not been effective enough in increasing Hb levels. LBW cases were also found in this study, which is around 9.3%. Pregnant women with anemia have a higher risk of LBW. This indicates that offering Fe to pregnant women has not been effective.

AN EPIDEMIOLOGICAL STUDY ON THE PREVALENCE OF HYPOTHYROIDISM IN PREGNANT WOMEN AND ITS OUTCOME

2021 ◽  
pp. 48-50
Author(s):  
Vinita singh ◽  
Sneha kumari
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Neonatal Outcome ◽  
Reproductive Age ◽  
P Value ◽  
Overt Hypothyroidism ◽  
Thyroid Disorder ◽  
Neonatal Complications ◽  
In Pregnancy

Thyroid disorders are the most common endocrine disorders affecting women of reproductive age group Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% Maternal hypothyroidism leads to many maternal and perinatal complications like miscarriage, gestational diabetes mellitus, pre-eclampsia, pre-term labor, placental abruption, and fetal death. AIMS AND OBJECTIVE: To nd out the effect of hypothyroidism on the course of pregnancy, to study the neonatal outcome, to know the prevalence of subclinical and overt hypothyroidism in pregnant women. MATERIALS AND METHODS: This prospective study was conducted in the department of Obstetrics and Gynecology, Nalanda medical college and hospital, Patna. All pregnant women attending the obstetric unit during this period were included in the study after informed consent 10 ml of blood sample of pregnant women was drawn at the rst visit in the rst trimester; then it was centrifuged and stored at -70 degree Celsius until assays, which were done after delivery, TFT was assessed by quantitative analysis of serum TSH and FT4 (ELISA). The pregnancy outcome variables like miscarriages, preterm deliveries, IUGR, preeclampsia, anemia, low birth weight, intrauterine fetal demise, antepartum hemorrhage, stillbirth, postpartum hemorrhage, birth asphyxia were studied. The neonatal outcome was also studied. The statistical analysis was done using the odds ratio. P-value <0.05 was considered signicant. RESULTS: Out of the 250 pregnant women 25 had hypothyroidism (9.5%). The prevalence of subclinical hypothyroidism was more as compared to the overtone (Table 2). Abortions were seen in 12.5% of subclinical and 11.1% of overt hypothyroid women. PIH and abruptions were signicantly higher in subclinical cases (P<0.05) while in the overt group both complications were higher as compared to the normal women but the p-value was not signicant for abruption. More of the hypothyroid women had preterm delivery (37.5% in subclinical and 44.4% in the overt group), Regarding neonatal complications, IUD and Early neonatal deaths were signicantly higher in overt hypothyroidism (P<0.01) Hypothyroid women had more low birth weight babies (31.25% in subclinical and 35.5% in overt) and IUGR babies (18.70% in subclinical and 22.21% in overt), CONCLUSION: The present study shows that, though the occurrence of hypothyroidism in pregnancy is less yet it causes many maternal and neonatal complications therefore universal screening of thyroid disorder should be done in pregnancy.

scholarly journals The performance of various anthropometric assessment methods for predicting low birth weight in adolescent pregnant women

2014 ◽  
Vol 17 (3) ◽  
pp. 761-774 ◽  
Author(s):  
Denise Cavalcante de Barros ◽  
Cláudia Saunders ◽  
Marta Maria Antonieta de Souza Santos ◽  
Beatriz Della Líbera ◽  
Silvana Granado Nogueira da Gama ◽  
...  
Keyword(s):  
Weight Gain ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
World Health ◽  
Ministry Of Health ◽  
Predictive Values ◽  
Low Weight ◽  
High Weight Gain ◽  
Anthropometric Assessment

Objective: To evaluate the performance of various anthropometric evaluation methods for adolescent pregnant women in the prediction of birth weight. Methods: It is a cross-sectional study including 826 adolescent pregnant women. In the pre-pregnancy body mass index (BMI) classification, the recommendations of the World Health Organization were compared with that of the Brazilian Ministry of Health and the Institute of Medicine (IOM) of 1992 and 2006. The gestational weight gain adequacy was evaluated according to the classification of IOM of 1992, of 2006 and of the Brazilian Ministry of Health. The newborns were classified as low birth weight (LBW) or macrosomic. Multinomial logistic regression was used for statistical analysis and sensibility, specificity, accuracy, positive and negative predictive values were calculated. Results: The evaluation, according to the Brazilian Ministry of Health, showed the best prediction for LBW among pregnant women with low weight gain (specificity = 69.5%). The evaluation according to the IOM of 1992 showed the best prediction for macrosomia among pregnant women with high weight gain (specificity = 50.0%). The adequacy of weight gain according to the IOM of 1992 classification showed the best prediction for LBW (OR = 3.84; 95%CI 2.19 - 6.74), followed by the method of the Brazilian Ministry of Health (OR = 2.88, 95%CI 1.73 - 4.79), among pregnant women with low weight gain. Conclusion: It is recommended the adoption of the Brazilian Ministry of Health proposal, associated with BMI cut-offs specific for adolescents as an anthropometric assessment method for adolescent pregnant women.

scholarly journals Teenage Pregnancy and Its Adverse Obstetric and Perinatal Outcomes at Lemlem Karl Hospital, Tigray, Ethiopia, 2018

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Ayele Mamo Abebe ◽  
Girma Wogie Fitie ◽  
Desalegn Abebaw Jember ◽  
Mihretab Mehari Reda ◽  
Getu Engida Wake
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Cesarean Delivery ◽  
Teenage Pregnancy ◽  
Perinatal Outcomes ◽  
Teenage Mothers ◽  
World Health ◽  
Premature Delivery ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension

Introduction. One of the major public health issues across the whole world these days is teenage pregnancy which is defined as being pregnant in the age ranging from 13–19 years. About 11% of all births which occurred worldwide accounted for girls aged 15 to 19 years. From these, 95% teenage deliveries occur in low- and middle-income countries. World health 2014 statistics show that complications during pregnancy and childbirth are the second cause of death for 15–19-year-old girls globally. The aim of this study was to determine adverse obstetrical and perinatal outcomes of teenage pregnancy among deliveries at Lemlem Karl General Hospital, Tigray, Ethiopia, 2018. Result. This study result showed that 17.5% of the teenagers and 6.8% of the adults deliver low birth weight neonates. From the total teenage mothers, about thirty-five (11.3%) of them had developed pregnancy-induced hypertension, whereas about thirteen (4.2%) of adults develop pregnancy-induced hypertension. Regarding cesarean delivery, forty (12.9%) of those teenage mothers deliver by a cesarean section while 58 (18%) of the adult mothers deliver by cesarean delivery. Teenage pregnancy was significantly associated with adverse obstetric and perinatal outcomes, a cesarean delivery (AOR: 0.57; 95% CI, 0.36–0.90), episiotomy (AOR: 2.01; 95% CI, 1.25–3.39), and low birth weight (AOR: 2.22; 95% CI, 1.13–4.36), and premature delivery were 2.87 (1.49–5.52). This study shows that adverse obstetric and perinatal outcomes were significantly associated with teenagers than adult mothers. Therefore, giving health education on focused ANC is very important to bring change to the teenager at this study area.

scholarly journals A study of dengue fever in pregnancy and its maternal and fetal prognosis

2017 ◽  
Vol 6 (8) ◽  
pp. 3414 ◽  
Author(s):  
Hanslata Gehlot ◽  
Om Prakash Yadav ◽  
Seema Sharma ◽  
Girdhar Gopal Nagar ◽  
Ayna Yadav ◽  
...  
Keyword(s):  
Intensive Care ◽  
Platelet Count ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Dengue Virus ◽  
Dengue Fever ◽  
Specific Antigen ◽  
Fetal Outcome ◽  
World Health ◽  
In Pregnancy

Background: Dengue is a vector borne viral disease. Female Anopheles mosquito is the vector for the disease. Recently, there is an increase in the incidence of dengue fever in adult population in South Asian countries. With increasing rate of adult dengue fever victims, the number of infected pregnant women has also been increased. Dengue, during pregnancy may be associated with various complications, including abortions, preterm delivery, maternal mortality, low birth weight, neonatal admissions and fetal anomalies. Timely intervention can improve the maternal as well as fetal outcome. This study was aimed to assess the clinical profile, maternal and fetal outcome of dengue fever during pregnancy.Methods: The study was carried out on 25 pregnant females diagnosed and serologically confirmed to have dengue fever and were admitted in Umaid hospital, associated to Dr. S. N. Medical College Jodhpur, Rajasthan, India. Patients were included irrespective of the period of gestation of contracting the disease. Serological testing for dengue virus specific antigen and antibody was done for the diagnosis of dengue fever. The World Health Organization (WHO) classification and case definitions 2009 were used to categorize the dengue patients. A predesigned proforma was used to collect data related to maternal and fetal consequences both during pregnancy and at birth, as well as the effect on the newborn. Informed and written consent was taken from all those who participated in the study.Results: Thrombocytopenia (platelet count <1.5lakh/mm3) was found in 22 (88%) patients out of which 6 (24%) of them had platelet count below 20,000 cells/mm3 and 3(12%) patients required platelet transfusion. Other complications observed were spontaneous abortions (4%); preterm birth (16%), oligohydramnios (8%) and antepartum hemorrhage (4%). One patient was admitted to Intensive Care Unit. Fetal distress and meconium stained amniotic fluid was observed in 16% and 12% patients respectively. Adverse fetal outcome was observed in form of low birth weight, prematurity. 8% of the babies required NICU admission and 4% were Intra Uterine Fetal Death (IUFD).Conclusions: Maternal infection with the dengue virus during antenatal period represents a real risk of premature birth. Early onset or late onset in pregnancy appeared to have a bad prognosis.  A high index of clinical suspicion is essential in any pregnant woman with fever during the epidemic. The treatment of dengue in pregnancy is mainly conservative as in non-pregnant adults. In case of high risk cases early referral to well-equipped health centres where technical, transfusion and intensive care facilities are available may prove lifesaving.

scholarly journals High prevalence of vitamin D deficiency among normotensive and hypertensive pregnant women in Ghana

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Linda Ahenkorah Fondjo ◽  
Worlanyo Tashie ◽  
William K. B. A. Owiredu ◽  
Enoch Appiah Adu-Gyamfi ◽  
Laila Seidu
Keyword(s):  
Vitamin D ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Hypovitaminosis D ◽  
Sub Saharan Africa ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
In Pregnancy

Abstract Background Hypovitaminosis D in pregnancy is associated with adverse health outcomes in mothers, newborns and infants. This study assessed the levels of 25-hydroxyvitamin D [25(OH)D] in normotensive pregnancies and in preeclampsia, evaluated the association between vitamin D deficiency and preeclampsia risk; and determined the foeto-maternal outcome in preeclamptic women with vitamin D deficiency. Methods This case-control study was conducted among pregnant women who visited the Comboni Hospital, in Ghana from January 2017 to May 2018 for antenatal care. A total of 180 pregnant women comprising 88 preeclamptic women (PE) and 92 healthy normotensive pregnant women (NP) were recruited. Socio-demographic, clinical and obstetric data were obtained using validated questionnaires. Blood pressure and anthropometrics were measured, and blood samples were collected for the estimation of 25- hydroxyvitamin D [25(OH)D] using enzyme-linked immunosorbent assay technique. Lipids (total cholesterol, triglycerides, HDL-cholesterol and LDL-cholesterol) were also estimated. Results A total of 81.7% of the study participants had vitamin D deficiency. Of these, 88.6% of the women with PE had vitamin D deficiency compared to 75.0% in the NP. Vitamin D levels were significantly reduced in the PE women compared to the normotensive pregnant women (p = 0.001). A higher proportion of the preeclamptic women who were vitamin D deficient had preterm delivery (p < 0:0001) and delivered low birth weight infants (p < 0:0001), and infants with IUGR (p < 0:0001) compared to the control group (p < 0:0001). Pregnant women with PE presented with significant dyslipidemia, evidenced by significantly elevated TC (p = 0.008), LDL (p < 0.0001), triglycerides (p = 0.017) and a significantly reduced HDL (p = 0.001) as compared to NP. In the preeclamptic women, serum 25(OH) D showed an inverse, but not significant association with TC (β = − 0.043, p = 0.722, TG (β = − 0.144, p = 0.210) and LDL (β = − 0.076, p = 0.524) and a positive, but not significant association with HDL (β = 0.171, p = 0.156). Conclusion The prevalence of vitamin D deficiency is high in both normotensive pregnancies and pregnancies complicated by preeclampsia but amplified in preeclampsia. Higher proportion of pregnant women with hypovitaminosis D had preterm babies and delivered low birth weight neonates. Additional studies are needed to explore the potential benefits and optimal dosing of vitamin D use in pregnancy, especially in sub-Saharan Africa.

scholarly journals PREVALENCE AND DETERMINANTS OF SEVERE ANAEMIA AMONG ANTENATAL WOMEN ATTENDING A TERTIARY CARE HOSPITAL IN MANIPUR

2020 ◽  
pp. 1-4
Author(s):  
Namoijam Basanti ◽  
Ningthoukhongjam Romita Devi* ◽  
Ningombam Joenna Devi ◽  
Ningthoukhongjam Shugeta Devi ◽  
Shugeta Devi Tutor Community Medicine Thangjam Netajini Devi ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Maternal Mortality ◽  
Pregnant Women ◽  
Post Partum ◽  
Severe Anaemia ◽  
Health Concern ◽  
Care Hospital ◽  
Severe Anemia ◽  
Post Partum Haemorrhage

Introduction: WHO defines anaemia in pregnancy as haemoglobin <11gm/dl and severe anaemia as haemoglobin < 7gm/dl.Anaemia is a major health concern during pregnancy particularly for the developing countries like India. Not many studies have been done so far regarding this health issue in this part of the country.Hence,this study was done to estimate the magnitude of the problem with focus on severe anemia. Objectives: To determine the prevalence of anaemia among pregnant women attending JNIMS Hospital, Manipur and classify the grades of anaemia and determine the factors leading to anaemia and study the outcomes of severely anaemic patients. Materials and methods: A prospective, hospital-based study was conducted in the Department of Obstetrics and Gynaecology,Jawaharlal Nehru Institute of Medical Sciences (JNIMS),Porompat,from August 2017 to April 2019 among pregnant women in second and third trimesters in a 20 months' duration,in a twice weekly survey,recruitment was done on all eligible women attending Obstetrics and Gynecology OPD, JNIMS using a pre-tested semi-structured questionnaire. Haemoglobin was measured using colorimetry method. All the very severely anaemic study-subjects were followed up for any interventions given and the pregnancy outcome until discharged alive or death. Data was analysed by SPSS version 20. Mean, standard deviation, Chi square test etc. were used for analysis. The study was approved by the Institutional ethics committee. Results: The prevalence of anaemia was found to be 30.8%; mild anaemia was found in 288(17.9%), moderate in 124 (7.8%) and severe anaemia was 82 (5.1%). Severe anaemia was found to be significantly associated with age group 34 years and above, Muslim community, rural residence, being illiterate, ANC less than three times, never taken supplemental iron,with increasing gravida and booking ANC visit after 12 weeks.Blood transfusion was given to 62 out of 82 (75.6%) patients and 20 patients (24.3%) received parenteral iron. Six patients (7.3%) had associated preeclampsia, 3 (3.6%) had ante-partum haemorrhage, and 4 (4.8%) had associated post-partum haemorrhage. There were 6 (7.3%) intrauterine deaths,10 preterm deliveries (12.1%),and 7 low birth weight babies (8.5%). There was one maternal mortality with the baby in utero. Conclusion: Almost around a third of the pregnant women suffered from anaemia with a sixth of them having severe anaemia.Three fourths of the pregnant women having severe anaemia received blood transfusion. Severe anemia was associated with pre-eclampsia, ante-partum haemorrhage and post-partum haemorrhage, intra-uterine deaths, preterm deliveries, low birth weight and maternal mortality. Regular antenatal checkups, adequate intake of iron and folic acid tablets and proper age at the time of pregnancy should be encouraged.

scholarly journals U-Shaped Association between Maternal Hemoglobin and Low Birth Weight in Rural Bangladesh

2021 ◽  
Author(s):  
Rebecca Carpenter ◽  
Masum Billah ◽  
Genevieve Lyons ◽  
Md Shahjahan Siraj ◽  
Qazi Rahman ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Newborn Health ◽  
Global Network ◽  
World Health ◽  
Placental Disease ◽  
The Mean ◽  
Health Registry ◽  
Disease Understanding

Low birth weight (LBW) is associated with a higher risk of neonatal mortality and the development of adult-onset chronic disease. Understanding the ongoing contribution of maternal hemoglobin (Hgb) levels to the incidence of LBW in South Asia is crucial to achieve the World Health Assembly global nutrition target of a 30% reduction in LBW by 2025. We enrolled pregnant women from the rural Tangail District of Bangladesh in a Maternal Newborn Health Registry established under The Global Network for Women’s and Children’s Health Research. We measured the Hgb of pregnant women at enrollment and birth weights of all infants born after 20 weeks gestation. Using logistic regression to adjust for multiple potential confounders, we estimated the association between maternal Hgb and the risk of LBW. We obtained Hgb measurements and birth weights from 1,665 mother–child dyads between July 2019 and April 2020. Using trimester-specific cutoffs for anemia, 48.3% of the women were anemic and the mean (±SD) Hgb level was 10.6 (±1.24) g/dL. We identified a U-shaped relationship where the highest risk of LBW was seen at very low (< 7.0 g/dL, OR = 2.00, 95% CI = 0.43–7.01, P = 0.31) and high (> 13.0 g/dL, OR = 2.17, 95% CI = 1.01–4.38, P = 0.036) Hgb levels. The mechanisms underlying this U-shaped association may include decreased plasma expansion during pregnancy and/or iron dysregulation resulting in placental disease. Further research is needed to explain the observed U-shaped relationship, to guide iron supplementation in pregnancy and to minimize the risk of LBW outcomes.

Sign in / Sign up

Export Citation Format

Share Document