SERIES OF DENGUE CASES IN PREGNANCY AND ITS OUTCOME

2021 ◽  
pp. 91-93
Author(s):  
Srinisha Soundararaja ◽  
Meghna Treesa Anton ◽  
K. Saraswath

Dengue is a vector-borne viral disease. It is a disease caused by any one of the four closely related viruses (DEN-1, DEN-2, DEN-3, or DEN-4). The viruses are transmitted to humans by the bite of an infected mosquito (Aedes aegypti). Recently, there is an increase in the incidence of dengue fever in adult population in South Asian countries. With an increasing rate of adult dengue fever victims, the number of pregnant women infected with dengue has also increased. Dengue, during pregnancy may be associated with various complications, including abortions, preterm delivery, maternal mortality, low birth weight, neonatal admissions, and fetal anomalies. Timely intervention can improve the maternal as well as fetal outcome. This study was aimed to assess the clinical prole, maternal and fetal outcome of dengue fever during pregnancy and post-delivery. This study shows various outcomes in different trimesters of pregnanc

2019 ◽  
Vol 3 (4) ◽  
pp. 141-143
Author(s):  
Indrajeet Singh ◽  
Naresh Sharma

The vector borne diseases of dengue and chikungunya mainly affect the African and South Asian countries. Its prevalence increases in the summer and monsoon seasons due to an  increase in breeding sites and External Incubation Period (EIP) of the virus. Primarily caused by an infectious bite of the Aedes aegypti female mosquito, this disease has a variety of systemic signs and symptoms. However, the oral manifesatations might be ignored. This review aims to enlightens the healthcare researchers with knowledge regarding the oral manifestations of dengue and chikungunya.


Author(s):  
Hanslata Gehlot ◽  
Om Prakash Yadav ◽  
Seema Sharma ◽  
Girdhar Gopal Nagar ◽  
Ayna Yadav ◽  
...  

Background: Dengue is a vector borne viral disease. Female Anopheles mosquito is the vector for the disease. Recently, there is an increase in the incidence of dengue fever in adult population in South Asian countries. With increasing rate of adult dengue fever victims, the number of infected pregnant women has also been increased. Dengue, during pregnancy may be associated with various complications, including abortions, preterm delivery, maternal mortality, low birth weight, neonatal admissions and fetal anomalies. Timely intervention can improve the maternal as well as fetal outcome. This study was aimed to assess the clinical profile, maternal and fetal outcome of dengue fever during pregnancy.Methods: The study was carried out on 25 pregnant females diagnosed and serologically confirmed to have dengue fever and were admitted in Umaid hospital, associated to Dr. S. N. Medical College Jodhpur, Rajasthan, India. Patients were included irrespective of the period of gestation of contracting the disease. Serological testing for dengue virus specific antigen and antibody was done for the diagnosis of dengue fever. The World Health Organization (WHO) classification and case definitions 2009 were used to categorize the dengue patients. A predesigned proforma was used to collect data related to maternal and fetal consequences both during pregnancy and at birth, as well as the effect on the newborn. Informed and written consent was taken from all those who participated in the study.Results: Thrombocytopenia (platelet count <1.5lakh/mm3) was found in 22 (88%) patients out of which 6 (24%) of them had platelet count below 20,000 cells/mm3 and 3(12%) patients required platelet transfusion. Other complications observed were spontaneous abortions (4%); preterm birth (16%), oligohydramnios (8%) and antepartum hemorrhage (4%). One patient was admitted to Intensive Care Unit. Fetal distress and meconium stained amniotic fluid was observed in 16% and 12% patients respectively. Adverse fetal outcome was observed in form of low birth weight, prematurity. 8% of the babies required NICU admission and 4% were Intra Uterine Fetal Death (IUFD).Conclusions: Maternal infection with the dengue virus during antenatal period represents a real risk of premature birth. Early onset or late onset in pregnancy appeared to have a bad prognosis.  A high index of clinical suspicion is essential in any pregnant woman with fever during the epidemic. The treatment of dengue in pregnancy is mainly conservative as in non-pregnant adults. In case of high risk cases early referral to well-equipped health centres where technical, transfusion and intensive care facilities are available may prove lifesaving.


Author(s):  
Wadhah Hassan Edrees ◽  
Nabil Mohammed Mogalli ◽  
Khalid Wahan Alabdaly

Background and objective: Classical dengue (DF) is a viral disease transmitted by the bite of an infected mosquito, usually Aedes aegypti or Aedes albopictus. Residents without access to sophisticated laboratory tools need simple clinical and/or laboratory indicators that can provide a reliable diagnosis of dengue fever before admission to the hospital. Therefore, this study was designed to evaluate some clinical and laboratory features among confirmed cases with dengue fever in the government of Hajjah, Yemen to differentiate between dengue (DF) and other febrile diseases in the dengue affected population. Methods: Clinical data and blood samples were collected from 46 confirmed cases of dengue fever, which were hospitalizedat the Yasser and Thabit Hospital from September to December 2019. The collected samples were examined for some hematological tests, including: hemoglobin (Hb), white blood cells counts (WBCs), and hematocrit (HCT), and a platelet count (PLT). Confirmation of dengue was performed with a non-structural protein tape (NS1). Results: The results obtained showed that males have a higher infection rate (73.91%) of DF compared to females (26.09%). The recurrence rate was also highest (69.56%) among the 16-30 year-olds. Regarding clinical symptoms, fever and headache occurred in 100%, nausea in 95.65%, and vomiting in 78.26% of the patients, while rashes were less frequent (19.56%). Hematological abnormalities frequently occurred with WBC (89.1%), PLT (84.78%), and Hb (63.04%), while HCT was only abnormal in 23.91% of cases. Conclusion: A high frequency of clinical and laboratory variants can distinguish dengue fever from other causes of infection; Dengue fever is most common in males between the ages of 16 and 30. This is the first report documenting the occurrence of dengue fever in Hajjah governorate, which requires more attention to prevent and control it. Further prospective studies are needed to build a valid and generalizable algorithm to guide the differential diagnosis of dengue fever in endemic countries such as Yemen.                    Peer Review History: Received 17 March 2021; Revised 11 April; Accepted 25 April, Available online 15 May 2021 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.  Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Dr. Bilge Ahsen KARA, Ankara Gazi Mustafa Kemal Hospital, Turkey, [email protected] Prof. Dr. Hassan A.H. Al-Shamahy,  Sana'a University, Yemen, [email protected] Dr. Muhammad Zahid Iqbal, AIMST University, Malaysia, [email protected] Similar Articles: SEROPREVALENCE OF DENGUE FEVER VIRUS AMONG SUSPECTED PATIENTS IN TAIZ GOVERNORATE-YEMEN


2020 ◽  
Author(s):  
Felestin Yavari Nejad ◽  
Kasturi Dewi Varathan

Abstract Dengue fever is a widespread viral disease and one of the world’s major pandemic vector-borne infections, causing serious hazard to humanity. The World Health Organisation (WHO) reported that the incidence of dengue fever has increased dramatically across the world in recent decades. WHO currently estimates an annual incidence of 50–100 million dengue infections worldwide. To date, no tested vaccine or treatment is available to stop or prevent dengue fever. Thus, the importance of predicting dengue outbreaks is significant. The current issue that should be addressed in dengue outbreak prediction is accuracy. A limited number of studies have conducted an in-depth analysis of climate factors in dengue outbreak prediction.


2019 ◽  
Vol 4 (1) ◽  
pp. 52 ◽  
Author(s):  
Baratang Lubisi ◽  
Phumudzo Ndouvhada ◽  
Donald Neiffer ◽  
Mary-Louise Penrith ◽  
Donald-Ray Sibanda ◽  
...  

Rift Valley fever (RVF) is a vector-borne viral disease of ruminants mainly, and man, characterized by abortions and neonatal deaths in animals and flu-like to more severe symptoms that can result in death in humans. The disease is endemic in Africa, Saudi Arabia and Yemen, and outbreaks occur following proliferation of RVF virus (RVFV) infected mosquito vectors. Vertebrate animal maintenance hosts of RVFV, which serve as a source of virus during inter-epidemic periods remain unknown, with wild and domestic suids being largely overlooked. To address this, we evaluated the virus neutralization test (VNT) for RVF antibody detection in suid sera, as a first step in assessing the role of suids in the epidemiology of RVF in Africa. Testing of experimental and field sera from domestic pigs and warthogs with a commercial RVF competitive antibody ELISA, served as a reference standard against which the VNT results were compared. Results indicate that VNT can detect anti-RVFV antibodies within three days post-infection, has an analytical specificity of 100% and diagnostic sensitivity and specificity of 80% and 97%, respectively. Although labour-intensive and time-consuming, the VNT proved suitable for screening suid sera and plasma for presence of RVFV antibodies in viraemic and recovered animals.


2012 ◽  
Vol 38 (9) ◽  
pp. 1125-1136 ◽  
Author(s):  
Narayan Jana ◽  
Sukumar Barik ◽  
Nalini Arora ◽  
Arun Kumarendu Singh

2012 ◽  
Vol 4 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Judith Angelitta Noronha ◽  
Esra Al Khasawneh ◽  
Vidya Seshan ◽  
Shanthi Ramasubramaniam ◽  
Savithri Raman

ABSTRACT Anemia during pregnancy is a global public health challenge facing the world today, especially in the developing countries. Anemia in pregnancy is an important contributor to maternal mortality/morbidity as well as to the low birth weight which in turn might contribute to increased percentage for infant mortality. Many epidemiological studies in the past have reported the problem in high magnitude. This review was conducted to identify the persistence of the problem in the South Asian countries during the last 5 years irrespective of iron supplementation as a measure to tackle this problem. Materials and methods A review of all published literature related to prevalence of anemia for a period of 5 years (2007- 2011) in South Asian countries was carried out. The online databases MEDLINE, CINAHL, Science Direct, Scopus, and Cochrane were used to identify relevant studies. Data from studies meeting inclusion/exclusion criteria were abstracted into a standardized form. Results Eleven studies with a total of 1,93,131 pregnant women were included in the review. The maximum and minimum reported prevalence rates of anemia during pregnancy were 80 and 18% respectively. The maximum and minimum prevalence of severe anemia affecting pregnant women is 20 and 2.7%. The risk factors that are involved are young age, educational status and socioeconomic status, poor birth spacing and lack of compliance to iron and folic acid supplementation. Conclusion Anemia is the most frequent maternal complication of pregnancy. All the 11 studies reviewed focused on assessing the prevalence of anemia during various stages of pregnancy. It shows anemia is prevalent from mild to severe degree with substantial variations across trimesters. The outcomes of these suggest prevalence of anemia is due to associated factors and lack of deficiency of vitamin B12, low BMI, infection with ascariasis, deficient dietary consumption of foods fortified with iron, low socioeconomic conditions and high parity. How to cite this article Noronha JA, Al Khasawneh E, Seshan V, Ramasubramaniam S, Raman S. Anemia in Pregnancy— Consequences and Challenges: A Review of Literature. J South Asian Feder Obst Gynae 2012;4(1):64-70.


2021 ◽  
Vol 10 (44) ◽  
pp. 3742-3746
Author(s):  
Suvarna Vishnu Nimkar

BACKGROUND Dengue fever is a vector-borne disease common in the tropics. It is known to have an adverse effect on pregnant women with unfavourable foetal outcomes. However, only a few studies are addressing this problem. Many of the studies had confounding factors such as the simultaneous occurrence of other vector-borne diseases and maternal health conditions. Therefore, the actual impact of dengue fever on pregnancy and pregnancy outcome is not clear. We wanted to study maternal and foetal outcomes in dengue positive pregnant females. METHODS This is a retrospective study done over 6 months in a tertiary care institute. Data regarding demography, obstetric history, biochemical parameters / blood investigation and pregnancy outcomes were collected and analysed. RESULTS Most of the dengue positive women presented with fever and thrombocytopenia in 44 % of cases. Obstetric complications such as preterm labour, abruption and postpartum haemorrhage (PPH) were common. Caesarean section rate was increased and the most common indication was foetal distress. The need for new-born intensive care unit (NICU) admission for new-born and foetal death was also increased. No evidence of congenital anomaly was found in the study. CONCLUSIONS Antenatal complications like preeclampsia, oligohydramnios; intrapartum complications like abruption, DIC, foetal distress and immediate postpartum complications like postpartum haemorrhage, need for blood, platelet transfusion were common in women with a history of dengue fever especially more in the low platelet group. The maternal and foetal outcomes were compromised and both required intensive care. A high index of clinical suspicion is essential in pregnant women presenting with fever and thrombocytopenia. Early diagnosis and management are essential. KEY WORDS Dengue Fever, Dengue in Pregnancy, Complications of Dengue Fever in Pregnancy


Author(s):  
Dr. Archana Mohana ◽  
Dr. Sujata Badoniya

The Aim of this study is to Review the timing of intervention which will provide the Best Outcome in Hypothyroidism in Pregnancy. Hypothyroid pregnant women are appropriately managed with regular antenatal checkup and thyroxine therapy during pregnancy, a good maternal and fetal outcome can be achieved and congenital cretinism and other neuro developmental sequele in the offspring can be averted. Keywords: Intervention, Hyperthyroidism, Pregnancy & Thyroid disease.


GYNECOLOGY ◽  
2018 ◽  
Vol 20 (2) ◽  
pp. 67-73
Author(s):  
T Yu Pestrikova ◽  
E A Yurasova ◽  
I V Yurasov ◽  
A V Kotelnikova

Genital herpes affects all population groups. 98% of the adult population worldwide have antibodies to the herpes simplex virus (HSV-1 or 2). This viral infection is a significant medical and social problem. HSV can lead to a complicated course of pregnancy, causing miscarriages, premature birth, intrauterine fetal death, systemic viral disease in newborns. There is evidence that HSV has a connection with malignant tumors of the prostate and cervix, contributing to their development. This literature review contains modern aspects of epidemiology, etiology, pathogenesis, clinic, diagnosis, treatment of genital herpes, including its recurring forms with valacyclovir (Valvir). Indications for hospitalization of patients with genital herpes were noted and the prognosis of this pathology was determined. The tactics of managing pregnant women with this pathology is presented.


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