scholarly journals Effects of anemia on pregnancy outcomes at Manipal Teaching Hospital

2020 ◽  
Vol 5 (3) ◽  
pp. 1201-1205
Author(s):  
Vibha Mahato ◽  
Pravin Shrestha

Introduction: Anemia is one of the most common disorders affecting the pregnant women in the developing countries like Nepal. Anemia during pregnancy is commonly associated with adverse pregnancy outcomes. Identifying anemia in pregnancy and knowing its common complications will help improve maternal quality care. Objectives: The objective - was to  assess the effects of anemia on pregnancy outcome at Manipal Teaching Hospital Methodology: This cross sectional study was conducted in Manipal Teaching Hospital from September 2019 to April 2020. A total of 200 anemic pregnantladies  attending obstetrics Out Patient Department were selected.Hemoglobinlevel was taken as criteria for deciding anemia and  to classify  severity of anemia.Anemia in pregnancy is defined by World Health Organization as hemoglobin level less than 11 gm/dl, and hemoglobin concentration of 10–10.9 g/dl, 7–9.9 g/dl, and <7 g/ dl was considered as mild, moderate, and severe anemia, respectively . All were treated depending on severity of anemia and followed up for maternal and perinatal outcome.Data was collected in Microsoft Excel and analyzed by using SPSS version 16. Result: We found moderate anemia in 129 (64.5%) cases followed by mild in 61(30.5%) and severe in 10(5%) cases. Common maternal complications in anemic patients werepremature rupture of membranein 30 (15%) cases and Urinary Tract Infection in 30(15%) cases.During puerperiumPostpartum Hemorrhage was observed in 12(6%) and wound infection in 9 (4.5%) cases of anemic patient. High incidence of adverse fetal outcome in the form of preterm in 39 (19.5%), Intrauterine growth restrictionin 23(11.5%), Intensive Care Unitadmission in28(14%),low birth weight in41(20.5%) and Intrauterine Death in4(2%) cases of anemic patients were seen. Conclusion: Maternal infection and adverse perinatal outcome in form of intrauterine growth restriction, Intensive Care Unitadmission, low birth weight and perinatal death were significantly associated with anemia in pregnancy.

Author(s):  
Hanslata Gehlot ◽  
Om Prakash Yadav ◽  
Seema Sharma ◽  
Girdhar Gopal Nagar ◽  
Ayna Yadav ◽  
...  

Background: Dengue is a vector borne viral disease. Female Anopheles mosquito is the vector for the disease. Recently, there is an increase in the incidence of dengue fever in adult population in South Asian countries. With increasing rate of adult dengue fever victims, the number of infected pregnant women has also been increased. Dengue, during pregnancy may be associated with various complications, including abortions, preterm delivery, maternal mortality, low birth weight, neonatal admissions and fetal anomalies. Timely intervention can improve the maternal as well as fetal outcome. This study was aimed to assess the clinical profile, maternal and fetal outcome of dengue fever during pregnancy.Methods: The study was carried out on 25 pregnant females diagnosed and serologically confirmed to have dengue fever and were admitted in Umaid hospital, associated to Dr. S. N. Medical College Jodhpur, Rajasthan, India. Patients were included irrespective of the period of gestation of contracting the disease. Serological testing for dengue virus specific antigen and antibody was done for the diagnosis of dengue fever. The World Health Organization (WHO) classification and case definitions 2009 were used to categorize the dengue patients. A predesigned proforma was used to collect data related to maternal and fetal consequences both during pregnancy and at birth, as well as the effect on the newborn. Informed and written consent was taken from all those who participated in the study.Results: Thrombocytopenia (platelet count <1.5lakh/mm3) was found in 22 (88%) patients out of which 6 (24%) of them had platelet count below 20,000 cells/mm3 and 3(12%) patients required platelet transfusion. Other complications observed were spontaneous abortions (4%); preterm birth (16%), oligohydramnios (8%) and antepartum hemorrhage (4%). One patient was admitted to Intensive Care Unit. Fetal distress and meconium stained amniotic fluid was observed in 16% and 12% patients respectively. Adverse fetal outcome was observed in form of low birth weight, prematurity. 8% of the babies required NICU admission and 4% were Intra Uterine Fetal Death (IUFD).Conclusions: Maternal infection with the dengue virus during antenatal period represents a real risk of premature birth. Early onset or late onset in pregnancy appeared to have a bad prognosis.  A high index of clinical suspicion is essential in any pregnant woman with fever during the epidemic. The treatment of dengue in pregnancy is mainly conservative as in non-pregnant adults. In case of high risk cases early referral to well-equipped health centres where technical, transfusion and intensive care facilities are available may prove lifesaving.


2015 ◽  
Vol 3 (3) ◽  
pp. 97-101
Author(s):  
Sunil Raja Manandhar ◽  
Dharma Sharna Manandhar

Background: A gestational age specific c birth weight, length and head circumference centile chart will help to identify intrauterine growth of a baby. Since the first published gestational age specific anthropometric study done in Nepal by Manandhar DS et al in 1993-94, there have been significant changes in socioeconomic conditions with improved health indicators. This study was done for identifying any changes in anthropometric measurements of the newborns born at Kathmandu Medical College Teaching Hospital (KMCTH). Objectives: To produce gestational age specific c birth weight, length and head circumference centile charts of the New born babies born at KMCTH and to calculate incidence of low birth weight (LBW) babies at KMCTH. Methods: This is a cross sectional observational study. Study was done at labour room, operation theatre, special care baby unit and postnatal wards of KMCTH. Study period was from 18th Aug 2011 to 28th Nov 2012 (15 months duration). Within 24 hours of birth, baby’s weight, length and head circumference were measured by medical officers and post graduate Residents of the Paediatrics Department. Mother’s weight, height and ethnicity were also recorded. Maturity of the baby was assessed by maternal history and corroborated by using modified Ballard score and Obstetric USG (Ultra sonogram) findings. Data were entered in excel database programme and later transferred into SPSS (Statistical package of social science) 16. Mean, standard deviation, range and percentiles values at different gestational age specific c groups were calculated. Results: A total of 2029 live babies without gross congenital malformations were included in this study, among which 57% (1154) were male. While analyzing maturity assessment, 89.1% (1808) were term, 8.7% (176) were preterm and 2.2 % (45) babies were post term. Mean birth weight at 40 weeks of gestation was 3.10 kg with Standard Deviation (SD) of 0.4 kg, mean head circumference was 34.0 cm (SD 1.2 cm) and mean length was 49.2 cm (SD 2.2 cm). Out of 2029 babies, 16.2% (328) babies were low birth weight (LBW) and 1.4% (28) babies weighed >4 kg. Conclusion: Percentile charts of newborns will help to assess the intrauterine growth of babies. Further more studies of these percentile charts will help to produce national level percentile charts of newborns of Nepal.DOI: http://dx.doi.org/10.3126/jkmc.v3i3.12244Journal of Kathmandu Medical CollegeVol. 3, No. 3, Issue 9, Jul.-Sep., 2014,Page: 97-101


2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Umriaty Umriaty ◽  
Juhrotun Nisa

AbstrakMenurut data WHO tahun 2015 jumlah BBLR di Indonesia berada di peringkat sembilan dunia dengan persentase BBLR lebih dari 15,5 % dari kelahiran bayi. Bayi yang lahir dengan berat badan kurang dari 2500 gram mempunyai resiko mengalami komplikasi. Keberlanjutan kehidupan bayi yang lahir dengan berat rendah juga sangat tergantung dari keadaan ekonomi, Pendidikan orang tua  dan perawatan pasca bayi lahir. Penelitian ini adalah penelitian survey analitik. Rancangan penelitian yang digunakan adalah  case control yaitu penelitian melibatkan kelompok kasus yaitu bayi BBLR yang berjumlah 32 dan bayi yang lahir dengan berat lahir normal sebagai kelompok kontrol yang berjumlah 32. Variabel faktor ibu yang diteliti pada penelitian ini adalah umur ibu, paritas, jarak kehamilan, status gizi ibu, anemia dalam kehamilan, pre eklampsi, dan riwayat berat lahir rendah pada kehamilan sebelumnya. Penelitian ini dilakukan pada bulan Oktober sampai dengan Desember 2017. Hasil penelitian menunjukkan bahwa sebagian besar bayi lahir  pada  umur ibu usia tidak beresiko 68, 8 %, paritas Pirmi/multigravida 90,6 %, jarak kehamilan ≥ 2 tahun 84,6 %, ibu hamil tidak KEK 68,8, anemia dalam kehamilan 50 %. Hasil analisis uji hubungan dengan Chi Square dan alpha 0,05 didapatkan 2 variabel mempunyai hubungan yang bermakna yaitu status gizi (p value 0,023), dan Anemia dalam kehamilan (p value 0,012). Kata kunci : faktor maternal, Bayi Berat Lahir Rendah AbstractAccording to WHO data in 201, the number of Low Birth Weight (LBW) of Indonesia is ranked ninth in the world with the percentage of LBW more than 15.5% of babies born. Babies born with weight less than 2500 grams have a risk of complications. The sustainability of a low birth weight baby's life is also highly based on the state of the economy, parental education and post-natal care.This research is an analytic survey research. The design of the research used was case control, the study involved case groups of 32 LBW infants and babies born with normal birth weight as a control group of 32. Maternal factor variables studied in this study were maternal age, parity, gestational distance, maternal nutritional status, anemia in pregnancy, pre-eclampsia, and a history of low birth weight in previous pregnancies. This study was conducted during October to December 2017. The results showed that most of the babies born at the age of the mother were not at risk 68,8%, Primi / multigravida 90.6%, the distance of pregnancy ≥ 2 years 84.6%, pregnant women not KEK 68.8, anemia in pregnancy 50%. Result of analysis of test of correlation with Chi Square and alpha 0,05 got 2 variables have significant relationship that is nutrition status (p value 0,023), and Anemia in pregnancy (p value 0,012). Keyword : maternal factor, Low Birth Weight


2010 ◽  
Vol 4 (07) ◽  
pp. 448-453 ◽  
Author(s):  
Catherine Olufunke Falade ◽  
Olukemi O Tongo ◽  
Oluwatoyin O Ogunkunle ◽  
Adebola Emmanuel Orimadegun

Background: Malaria in pregnancy remains a major cause of infant mortality through its contribution to preterm delivery, low birth weight and intrauterine death. Methodology: During a cross-sectional study of 983 mothers delivering in a secondary health care facility in Ibadan, southwestern Nigeria, an area of high malaria transmission, the effect of maternal and placental malaria parasitaemia on newborn anthropometry was evaluated. Malaria parasitemia was detected by microscopy of Giemsa stained thick blood smears. Results: Placental, maternal and combined placental and maternal malaria parasitaemia rates at the time of delivery were 13.1%, 12.7% and 11.1% respectively. The geometric mean parasite densities in maternal and placental smears were significantly higher in primigravid mothers than others (p = 0.004 and 0.002 respectively). Low birth weight rate was higher among babies born to mothers with maternal parasitaemia compared to those without (8.0 % versus 6.3%, p < 0.05). The mean birth weight was lower in neonates of mothers with peripheral and placental parasitaemia by 138 g and 122 g (p = 0.01 and 0.02) respectively, while the respective difference was up to 168 g and 151 g among primigravidae (p = 0.03 and 0.04). Neonates of mothers with maternal and placental parasitaemia had a lower mean length than those without parasitaemia (48.2 vs 49.2cm, p = < 0.0001 and 48.5 vs 49.2cm p = 0.02 respectively). Occiptofrontal circumference and ponderal indices were not significantly affected by maternal malaria parasitaemia. Conclusion: Malaria in pregnancy results in symmetric foetal growth restriction and the effect is more marked among primigravid mothers. 


2007 ◽  
Vol 78 (12) ◽  
pp. 2266-2276 ◽  
Author(s):  
Fernanda Mafra Siqueira ◽  
Luís Otávio Miranda Cota ◽  
José Eustáquio Costa ◽  
João Paulo Amaral Haddad ◽  
Ângela Maria Quintão Lana ◽  
...  

2021 ◽  
Vol 10 (2) ◽  
pp. 183-190
Author(s):  
Maxwell Dapar ◽  
Benjamin Joseph ◽  
Rotkangmwa Okunola ◽  
Josiah Mutihir ◽  
Moses Chingle ◽  
...  

Background and Objective: Antiretroviral therapy (ART) has transformed human immune deficiency virus (HIV) infection from a death sentence to a chronic syndrome, allowing infected individuals to lead near-normal lives, including achieving pregnancy and bearing children. Notwithstanding, concerns remain about the effects of ART in pregnancy. Previous studies suggested contradictory associations between ART and pregnancy. This study determined birth outcomes in pregnant women who accessed ART between 2004 and 2017 at a major tertiary hospital in North Central Nigeria. Methods: This was a retrospective study of 5,080 participants. Ethical clearance was obtained from the Institutional Review Board of the Harvard T. H. Chan School of Public Health Boston. A pro forma for data abstraction was designed and used to collect data. Abstracted data were sorted and managed using SPSS® version 22. The Chi-square test was used to calculate the proportions of pregnancy outcomes. One-way analysis of variance was used to test the effect of antiretroviral drug regimens on mean birth weight and gestational age at delivery. All levels of significance were set at p 0.05. Results: Pregnancy outcomes were recorded as live birth (99.8%), stillbirth (0.2%), preterm delivery (6.6%), and low birth weight (23%). There was a statistically significant association between ART in pregnancy and low birth weight {χ2[(5, n = 3439) = 11.99, p = 0.04]}. The highest mean birth weights were recorded in participants who received drug combinations with protease inhibitors or efavirenz, in contrast to participants who received Nevirapine, stavudine and Emtricitabine/Tenofovirbased regimens. However, there was no significant difference in the gestational age of babies at birth for the six ART regimens in the study. Conclusion and Global Health Implications: Findings support the benefits of ART in pregnancy, which is in line with the testing and treatment policies of the 90-90-90 targets for ending HIV by the year 2030.   Copyright © 2021 Dapar et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.


2015 ◽  
Vol 6 (6) ◽  
pp. 53-59
Author(s):  
Godwin J Ibanga ◽  
Aniekan M Abasiattai ◽  
Emem A Bassey ◽  
Michael Ukpe ◽  
Olujimi A Olatunbosun ◽  
...  

Background: Malaria is the most common human parasitic disease and continues to be a complex and overwhelming global health problem, especially in sub-Saharan Africa. Placental malaria, one of the major features of malaria in pregnancy has been associated with serious adverse health consequences to both the mother and her fetus. Objective: This study sought to determine the prevalence of maternal, cord, and placental malarial parasitaemia at parturition, the association between maternal and placental parasitaemia, and also the association between placental parasitaemia and pregnancy outcomes. Materials and Methods: A descriptive cross-sectional design was used to study 330 pregnant women selected by the systematic random sampling technique as they presented in the labour ward of University of Uyo Teaching Hospital, Uyo between April, 2012 and September, 2012. Pre-delivery, maternal peripheral blood was taken for malaria parasite (MP) and packed cell volume (PCV). Post delivery, cord blood was taken for MP and PCV estimation while placental blood was examined for MP. Neonatal demographic and clinical characteristics were also obtained. The data was analyzed using SPSS version 17. Level of statistical significance was set at P less than 0.05 (P < 0.05). Results: The mean age of the respondents was 28.8 ± 4.4 years. The prevalence of maternal, cord, and placental parasitaemia were 30.3%, 14.8% and 18.2% respectively. There was a strong correlation between maternal parasitaemia and placental parasitaemia (rho = 0.75, P< 0.001). Also, a significant linear association between cord parasitaemia and placental malaria (rho = 0.87, p< 0.001) was found. Placental malaria predisposed to low birth weight (OR 1.01{95%CI 1.001 – 1.02}, p = 0.04) and fetal anaemia (OR 1.02{95%CI 1.01 – 1.03}, p < 0.001. Conclusion: There is a relatively high prevalence of placental parasitaemia at parturition. Placental malaria is associated with adverse pregnancy outcomes such as low birth weight, fetal anaemia and cord parasitaemia. Proven strategies to prevent malaria in pregnancy such as use of ITNs and IPT and free antenatal care should be intensified to curb this deadly but preventable disease.DOI: http://dx.doi.org/10.3126/ajms.v6i6.12401Asian Journal of Medical Sciences Vol.6(6) 2015 53-59


2021 ◽  
Vol 15 (5) ◽  
pp. 1456-1459
Author(s):  
Z. Khoshdel ◽  
S. Tomas

Aim: A prospective study on Impact of Anemia and Iron Supplementation in Pregnancy, Baptist Hospital, Bangalore, India Methodology: the prospective observational study was conducted for 6 months from September 2016_Febrry to 2017. All inpatients women who are pregnant and anemic. The patient data collection was used to collect all the details like inpatient number, age, sex, social history, history, laboratory data, diagnosis, therapeutic management. All inpatients diagnosed anemia in pregnancy and pregnant women without anemia. Fulfilling the inclusion criteria will be enrolled into the study and their prescriptions will be analyzed on daily basis. The prescription guidelines, Micromedex, interaction checker, drug interaction database, and Stockley's drug interaction book 8 edition. The drug interaction in prescription was collected and then compare with guidelines. When the analysis of prescription was completed then all data entered into the appropriate software and the results were gained. Results: The present study was focused to find out the presence of anemia in 110 pregnant women who were admitted to gynecology and OBG wards of BBH (Bangalore Baptist Hospital). Presence study showed that anemia was Confirmed in 50 patients. Of these 28(25.4%) of them diagnosed as mild anemic, 20 (18.1%) Of them with Moderate and 2(1.8%) of them as severe anemic patients. The result of this study showed that LBW is higher in anemic women 19(25%) compared to non-anemic 17(21%). Conclusion: The present study showed from a total of 110 patients were included in this study, anemia was confirmed in 50 patients. Of these 28(25.4%) of them diagnosed as mild anemic, 20(18.1%) Of them with Moderate and 2(1.8%) of them as severe anemic patients. More low-birth-weight (LBW) babies were born to anemic mothers. Anemia in pregnancy may be reduced by proper Iron and folic acid supplementation which can be improved through providing proper ANC services. Has also a recognizable association with fetal outcome. Keywords: Anemia, Iron, anemia, iron supplementation, pregnancy, low birth weight.


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