scholarly journals Comparison between Mifepristone and Ulipristal acetate as an alternative to surgical management of uterine fibroids (Leiomyoma) in symptomatic patients of reproductive age group in Asian population

2017 ◽  
Vol 7 (1) ◽  
pp. 109
Author(s):  
Ashish R. Kale
Keyword(s):  
Prospective Observational Study ◽  
Uterine Fibroids ◽  
Asian Population ◽  
Reproductive Age ◽  
Age Group ◽  
Transabdominal Ultrasound ◽  
Ulipristal Acetate ◽  
Reproductive Age Group

Background: Present study was a randomised prospective observational study carried out at Ashakiran Hospital and IVF centre Pune, Maharashtra, India to evaluate the efficacy, safety, and quality of life by using Ulipristal acetate 10 mg and Mifepristone 25 mg daily doses to treat uterine fibroids of two subgroups involving fibroids <3 cm and fibroids 3 to 5 cm all are in reproductive age group with symptomatic in nature over 3 months.Methods: A total number of 40 patients were recruited in the study of which they were divided into two groups according to the size of the fibroid as <3cm and 3-5cm as seen on transvaginal as well as transabdominal ultrasound. Further they were randomly assigned to either mifepristone or ulipristal orally with each category having 10 patients each to assess changes in fibroid size, in symptomatic pain reduction, menorrhagia and in quality of life.Results: The 25-mg dosage of Mifepristone is shown to be a good and effective way of treatment in fibroids less than 3 cm in achieving 40% reduction in size and 50% reduction in menorrhagia as compared to Ulipristal 10 mg which acts better in other subgroup of size 3-5 cm of fibroids.Conclusions: Still larger RCTs are needed to study the long-term benefits of these drugs.

Polycystic ovary syndrome

2020 ◽  
pp. 528-535
Author(s):  
Zhongwei Huang ◽  
Eu Leong Yong
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Endometrial Hyperplasia ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Endocrine Disorders ◽  
Age Group ◽  
Ovary Syndrome ◽  
Reproductive Ageing ◽  
Reproductive Age Group

Polycystic ovary syndrome (PCOS) is an enigmatic condition and its pathophysiology remains to be determined but it is likely to involve the androgen, insulin, and anti-Mullerian hormone pathways. PCOS is diagnosed in women in the reproductive age group based on the Rotterdam criteria. The spectrum of disease involves various phenotypes based on the current diagnostic criteria and this may have reproductive, metabolic, and endocrine consequences. Reproductive issues include that of irregular menstrual cycles and anovulation. Metabolic disorders such as insulin resistance, obesity, dyslipidaemia, and hypertension must be screened for in all women who are diagnosed with PCOS. Long-term risks of metabolic and endocrine disorders in women with PCOS still need further confirmation with more robust data. Reproductive ageing appears to be increased in women with PCOS and they seem to menopause at a later age. Thus far, PCOS appears to be associated with endometrial hyperplasia and cancer.

scholarly journals Reversible Long Term Contraceptives Utilization among Married Women of Reproductive Age Group in Areka Town, Southern Ethiopia

2020 ◽  
Vol 30 (6) ◽  
Author(s):  
Samson Kastro Dake ◽  
Temesgen Lera Abiso
Keyword(s):  
Low Income ◽  
Statistical Significance ◽  
Married Women ◽  
Reproductive Age ◽  
Low Income Countries ◽  
Southern Ethiopia ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Reproductive Age Group

BACKGROUND፡ In low income countries, bearing many children is the main factor affecting maternal health. This study aimed to estimate the prevalence of reversible long term contraceptives utilization and identify factors associated with it among married women of child bearing age in Areka District in South EthiopiaMETHODS: We conducted a community-based cross-sectional survey involving systematically recruited 346 married women of reproductive age group. Data was collected using a structured interviewer-administered questionnaire on May 2019. We used SPSS version 25 for data entry and analyses. Bivariate logistic regression analysis was used to select exposure variables with crude association. Multivariate analysis was done to control for potential confounders and identify predictors of the outcome. Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI)was reported, and statistical significance was declared at p<0.05.RESULTS: The prevalence of reversible long term contraceptives utilization among married women of reproductive age group was 134(38.7%). Utilization of Reversible Long Term Contraceptives (RLTCs) was positively associated with being protestant Christian religion follower, advanced educational status, history of abortion, and having a better attitude towards reversible long term contraceptives. In other words, being housewife, being daily laborer, having no radio in the household and making fertility decisions alone were negatively associated.CONCLUSION: The prevalence of RLTCs in the study area was high. Women should be empowered educationally through other alternative opportunities to formal school. In addition to electronic media, different community events and community conversations should be used to convey messages on contraceptives particularly RLTCs. Behavioral change communications would benefit women in shaping their attitudestowards RLTCs.

scholarly journals Reversible Long Term Contraceptives Utilization among Married Women of Reproductive Age Group in Areka town, South Ethiopia

2020 ◽  
Author(s):  
Samson Kastro Dake ◽  
Temesgen Lera
Keyword(s):  
Low Income ◽  
Statistical Significance ◽  
Married Women ◽  
Reproductive Age ◽  
Low Income Countries ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
South Ethiopia ◽  
Reproductive Age Group

Abstract Background: In low income countries, maternal mortality rate remains high. Bearing many children is the main factor affecting maternal health. This study aimed to estimate the prevalence of reversible long term contraceptives utilization and identify factors associated with it among married women of child bearing age in Areka town in South Ethiopia Methods: We did a community-based cross-sectional survey involving systematically recruited 346 married women of reproductive age group. Data was collected using a structured interviewer-administered questionnaire on May 2019. We used SPSS version 25 for data entry and analyses. Bivariate logistic regression analysis was used to select exposure variables with a crude association. Multivariate analysis was done to control for potential confounders and identify predictors of the outcome. Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI) was reported and statistical significance was declared at p <0.05.Results: The prevalence of reversible long term contraceptives utilization among married women of reproductive age group was 38.7% in the study area. Utilization of reversible long term contraceptives was positively associated with being Protestant Christian religion follower (AOR=5.33; 95% CI: 1.63, 17.40), advanced educational status (AOR=5.78; 95% CI: 1.97, 17.02), history of abortion (AOR=7.17; 95% CI: 2.81, 18.27), and having a better attitude towards reversible long term contraceptives (AOR=2.85; 95% CI: 1.46, 5.57). Whereas, being a housewife (AOR=.27; 95% CI: .09, .79) and daily laborer (AOR=.14; 95% CI: .02, .80), having no radio in the household (AOR=.40; 95% CI: .16, .99) and making fertility decisions alone (AOR=.12; 95% CI: .04, .37) were negatively associated. Conclusion: Women should be empowered educationally through other alternative opportunities to school. On top of electronic media, other alternative media should be used to convey messages on contraceptives particularly RLTCs. Behavioral change communications would benefit women in shaping their attitudes towards RLTCs.

scholarly journals Study on the Prevalence and Characteristics of Metabolic Syndrome in Women of Reproductive Age Group with Polycystic Ovarian Syndrome

2017 ◽  
Vol 9 (4) ◽  
pp. 341-347
Author(s):  
Rekha R Madusudhanan ◽  
Bindu Nambisan ◽  
Mayadevi Brahmanandan ◽  
Sreekumari Radha
Keyword(s):  
Metabolic Syndrome ◽  
Polycystic Ovarian Syndrome ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Ovarian Syndrome ◽  
Reproductive Age Group

ABSTRACT Introduction Polycystic ovarian syndrome (PCOS) is an endocrine disorder affecting all age groups and presenting with myriad problems like menstrual irregularities, hirsutism, anovulatory infertility, and long-term complications like diabetes, cardiovascular problems, etc. Aim Study was aimed at finding the prevalence, characteristics, and various risk factors of metabolic syndrome (MS) in reproductive age group in our hospital. Materials and methods Using statistical table, a sample size of 131 was calculated and patients were recruited as per inclusion criteria. Polycystic ovarian syndrome was diagnosed by the American Society for Reproductive Medicine (ASRM)/European Society of Human Reproduction and Embryology (ESHRE) criteria. After informed consent, a detailed history was obtained and physical examination was carried out to assess, body weight, height, body mass index (BMI), waist—hip ratio (WHR), and blood pressure (BP). Fasting blood glucose, triglycerides, and high-density lipoprotein (HDL) were measured for each woman Results Prevalence of MS in our study was 45.8%; 26.7% of patients had a combination of increased waist circumference, raised triglycerides, and low HDL; 55.2% of patients had a fasting blood sugar (FBS) levels more than 100 mg%. Age of the patient was a statistically significant risk factor of MS with 100% of patients in the age group of 35 to 39 presenting with MC. Body mass index was also a statistically significant risk factor with 82.6% with BMI > 30 having MC. Other important risk factors include a WHR more than 0.95, presence of diabetes in mother or sister, and presence of acanthosis; 71% of patients with WHR more than 0.95 had MC. Age of menarche, duration of menstrual cycles, and hirsutism showed no significant relationship. Conclusion An outstanding fact that emerged in this study was that 94% of women with PCOS had HDL values <50 mg/dL. And 58% had triglycerides more than 150 mg/dL. Hence, lifestyle modification and early intervention will hopefully spare long-term complication of PCOS. How to cite this article Madusudhanan RR, Nambisan B, Brahmanandan M, Radha S. Study on the Prevalence and Characteristics of Metabolic Syndrome in Women of Reproductive Age Group with Polycystic Ovarian Syndrome. J South Asian Feder Obst Gynae 2017;9(4):341-347.

scholarly journals Quality of Life and Stigma among Women with Epilepsy during Their Reproductive Years

2021 ◽  
Vol 11 (1) ◽  
pp. 63-71
Author(s):  
Pallerla Srikanth ◽  
Mysore Narasimha Vranda ◽  
Priya Treesa Thomas ◽  
Kenchaiah Raghvendra
Keyword(s):  
Quality Of Life ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Care Hospital ◽  
Age Group ◽  
Stigma Scale ◽  
The Impact ◽  
The Relationship ◽  
Reproductive Age Group

Background and Purpose: The purpose of this study was to understand the relationship between quality of life and stigma among reproductive age group women with epilepsy.Methods: A cross-sectional descriptive study was conducted to assess the data from the 49 women with epilepsy from a tertiary care hospital in India. Quality of life was evaluated with the quality of life in epilepsy-31 questionnaire and stigma was evaluated with the stigma scale of epilepsy. Data also included socio-demographic and clinical characteristics.Results: The mean age of the participants was 24.67±3.72 years. Quality of life total score (r=-0.485**) and seizure worry domain (r=-0.427**) were significantly negatively correlated with stigma total score at p<0.01 level. Being uneducated, married, unemployed, having children, having generalized tonic-clonic seizures, duration of illness (˃10 years), and consuming levetiracetam, anti-epileptic drug (AED), were the significant contributing factors for low quality of life among women with epilepsy during the reproductive age group. Belonging to lower socio-economic status and taking more than two AEDs were also associated with lower quality of life among women with epilepsy, which are trending towards significance.Conclusions: The study assessed the relationship between the quality of life and the Stigma scale of epilepsy and demonstrated the impact of stigma and quality of life on socio-demographic and clinical variables of women with epilepsy under the reproductive age group. To enhance the quality of life and reduce the stigma levels among women with epilepsy, some of the modifiable parameters can be considered by the multidisciplinary health care professionals from the findings of the current research.

scholarly journals Is it safe to perform myomectomy in first trimester of pregnancy? The report of two cases

2021 ◽  
Vol 6 (2) ◽  
pp. 170-174
Author(s):  
Murat Celiloglu ◽  
◽  
Samican Ozmen ◽  
Sefa Kurt ◽  
Orkun Ilgen
Keyword(s):  
Uterine Fibroids ◽  
First Trimester ◽  
Reproductive Age ◽  
Benign Tumors ◽  
Age Group ◽  
Second Trimester ◽  
Review Of The Literature ◽  
First Trimester Of Pregnancy ◽  
Reproductive Age Group

Uterine fibroids are the most common benign tumors in women in the reproductive age group. The incidence of fibroids during pregnancy varies between 1.6 and 10.7%. In 10% of these cases, fibroids lead to complications. The management in symptomatic patients is conservative, and the surgical treatment is delayed until after birth due to its risks. In the last two decades, it has been shown that myomectomy can be an alternative treatment in selected cases, especially in second-trimester pregnancies. However, the data on the success of myomectomies performed earlier in pregnancy are limited. In this case report, we present two cases who were admitted to our clinic during the first trimester of pregnancy and had complicated fibroids. The diagnosis, the follow up and the treatment are presented with the review of the literature.

scholarly journals ROLE OF STHAULYA IN THE DEVELOPMENT OF OBESE PCOS: A REVIEW

2020 ◽  
Vol 11 (6) ◽  
pp. 102-104
Author(s):  
Bindya R ◽  
Maya Balakrishnan ◽  
Giby Thomas
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Reproductive Age ◽  
Age Group ◽  
Endocrine Dysfunction ◽  
Menstrual Irregularities ◽  
Exact Correlation ◽  
Ovarian Syndrome ◽  
Reproductive Age Group

The polycystic ovarian syndrome is an extremely prevalent heterogeneous disorder affecting women in the reproductive age group. Symptoms may include menstrual irregularities, hyperandrogenism, or another endocrine dysfunction. Women with PCOS are more likely to be obese and are evident by their elevated BMIs and Waist: Hip ratios. These ratios reflect an android or central pattern of obesity which are the risk factors for cardiovascular disease one of the long-term consequences of PCOS. Obesity or sthoulya is a Santharpanajanya roga. Athisthoulyam is also mentioned under Ashtou ninditha purushas. An exact correlation of PCOS cannot be found in our classics; rather most clinical features are seen scattered among the symptoms and diseases mentioned in the context of Streeroga. Main menstrual irregularities seen in PCO women are oligomenorrhoea, amenorrhoea, and DUB which are found in the context of Artava Vyapat like Artavakshaya, Nashtartava, and Asrigdhara respectively. Anovulation resulting in amenorrhoea can be compared with Vandya yonivyapat and Pushpagni Jataharini.

scholarly journals Analysis of Preterm Induction of Labour

2020 ◽  
Vol 5 (9) ◽  
pp. 860-864
Author(s):  
Kritika Agrawal ◽  
Shubhangi Mande ◽  
Lakshmi Rachakonda
Keyword(s):  
Preterm Birth ◽  
Prospective Observational Study ◽  
Reproductive Age ◽  
Induction Of Labour ◽  
Labour Induction ◽  
Age Group ◽  
Bishop Score ◽  
Medical College ◽  
Number Of Patients ◽  
Reproductive Age Group

Worldwide 20-30% of labour cases are induced. We conducted an analysis to evaluate the success of labour induction for indicated preterm birth A prospective observational study was conducted among 50 patients admitted in the Department of OBGY, MGM Medical College and Hospital, Aurangabad from 1st March 2019 to 31st March 2020. There was a total of 50 deliveries during this period. The preterm induction majorly includes 20-34 years as this is the commonest reproductive age group seen in our hospital. More number of Hindus underwent induction. Multigravida requires induction more as compared to primigravida. More number of patients were induced between 32-36 weeks, reason being PPROM, severe preeclampsia, IUD and severe FGR. Vaginal delivery is more likely irrespective of bishop score. Induction of labour remains relevant obstetrics procedure and its outcome will depend on proper choice of patients and close intrapartum monitoring

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