scholarly journals A prospective randomized trial to compare side effects of early versus late removal of Foley’s catheter and vaginal pack following vaginal hysterectomy

2018 ◽  
Vol 7 (7) ◽  
pp. 2693
Author(s):  
Ayesha Gupta ◽  
Reddi Rani P.
Keyword(s):  
Vaginal Hysterectomy ◽  
Urine Culture ◽  
Operative Morbidity ◽  
Early Removal ◽  
Group I ◽  
Group Ii ◽  
Foley’S Catheter ◽  
Vaginal Pack ◽  
Removal Group ◽  
Febrile Morbidity

Background: There is a controversy about the ideal time for removal of catheter and vaginal pack following vaginal hysterectomy. The present study was undertaken to compare post-operative morbidity in early and late removal of Foley’s catheter and vaginal pack.  The aim of this study is to compare post-operative morbidity in early and late removal of Foley’s catheter and vaginal pack following vaginal hysterectomy.Methods: This was a prospective randomized study with n=100 of those women who were undergoing vaginal hysterectomy with or without pelvic floor repair and fulfilled the inclusion criteria. After informed written consent, they were assigned to Foley’s catheter and vaginal pack removal group in 6 hours (group I, n=50) or 24 hours removal group (group II, n=50). Primary parameters used to assess were urine routine and microscopy, urine culture and sensitivity on post-operative day 2, need for re-catheterization and repacking, febrile morbidity, ambulation, vault infection and post-operative hospital stay duration were analyzed in both groups.Results: Febrile morbidity was found in 6% and 8%, Positive urine culture was found in 10% and 20%, Rate of re-catheterization was 10% in group I and group II respectively. Vaginal bleeding after pack removal and repacking was in 6% in group I whilst none had in group II.Conclusions: Early removal was associated with less incidence of urinary tract infection, and increased rate of re-catheterization and repacking. Needs larger comparative studies to support the practice of early removal.

scholarly journals Adjunctive intrauterine Foley’s Catheter Balloon adding to hypogastric artery ligation in the conservative management of morbid adherent placenta previa

2018 ◽  
Vol 7 (6) ◽  
pp. 2093
Author(s):  
Hany F. Sallam ◽  
Nahla W. Shady
Keyword(s):  
Blood Loss ◽  
Placenta Previa ◽  
Hypogastric Artery ◽  
Artery Ligation ◽  
Cesarean Hysterectomy ◽  
Adherent Placenta ◽  
Group I ◽  
Estimated Blood Loss ◽  
Group Ii ◽  
Foley’S Catheter

Background: Objective of present study was to demonstrate the efficacy of Foley’s catheters balloon tamponade as an adjuvant to control blood loss during and after a caesarian section in patient undergone hypogastric artery ligation (HAL) due to morbid adherent placenta previa (MAPP).Methods: A single-center retrospective case-control clinical trial was carried out in a tertiary university hospital between March 2015 and March 2018, 124 women were undergoing cesarean delivery for MAPP, were managed conservatively either with HAL or HAL plus inflated Intrauterine Foley’s Catheter Balloon to control post-partum hemorrhage secondary to MAPP. In the case of conservative treatment protocol failure, cesarean hysterectomy was performed.Results: 124 women were enrolled (n=62 in each group). group of women received HAL plus Intrauterine Foley’s Catheter Balloon (group II)) showed a significant reduction in intraoperative and 4 hours post-operative blood loss compared with (Group I) which received HAL without Intrauterine Foley’s Catheter Balloon. (P = 0.0001,0.0.015), so the overall estimated blood loss in group II showed significant reduction compared with group I (P = 0.0001).Conclusions: Adjunctive intrauterine Foley's catheter balloon adding to HAL ligation in the management of MAPP is a novel combination approach have proved to be effective to control of intraoperative and PPH and to preserve the uterus as possible and change in the concept of MAPP management always mandates hysterectomy. And may become an alternative valid option to planned cesarean-hysterectomy in well-selected cases who have a strong desire for future fertility.

scholarly journals Evaluation of Closure versus Non-closure of Vaginal Vault after Non-descent Vaginal Hysterectomy

2021 ◽  
Vol 12 (1) ◽  
pp. 45-49
Author(s):  
Mousumi Saha ◽  
Ratu Rumana Binte Rahman ◽  
Gulshan Ara ◽  
Florida Rahman ◽  
Raunak Jahan
Keyword(s):  
Blood Transfusion ◽  
Vaginal Hysterectomy ◽  
Computer Software ◽  
Pelvic Abscess ◽  
Vaginal Vault ◽  
Gynecological Disorders ◽  
Abdominal Approach ◽  
Group I ◽  
Significant Difference ◽  
Group Ii

Introduction: Non-descent vaginal hysterectomy has been considered a valid alternative to the abdominal approach and is also preferred for benign uterine diseases without descent of uterus because it is associated with fewer complications. Vaginal vault is the enlargement of the internal end of the vagina which is usually closed during vaginal hysterectomy. This study was done to see the outcome of vault closure versus non-closure in non-descent vaginal hysterectomy in non-prolapsed uterus. Methods: This prospective study was done in Obstetrics and Gynae Department, Sir Salimullah Medical College and Mitford Hospital during the period of July 2011 to December 2011. A total number of 50 patients with benign gynecological disorders without descent of uterus who admitted for hysterectomy were enrolled in this study. Among them, 25 patients had the vault close (group I) whereas 25 patients had an open vault(group11). Indication for hysterectomy, complications, blood transfusion, hospital stay (day) and histopathological findings were assessed for both groups. Statistical analyses of the results were obtained by using window based computer software devised with Statistical Packages for Social Sciences (SPSS-20). Results: Majority of the patients was found in the age group of 41-45 years in both groups, which was 12(48.0%) in Group I and 18(72.0%) patients in Group II. Blood transfusion was needed in 5(20.0%) and in 6(24.0%) in Group I and Group II respectively. Post operative complications after 15 days of follow-up, pelvic abscess was found 4.0% in Group I & not found in Group II. UTI was not found in Group I but 4.0% found in Group II. Conclusion: Outcomes were almost similar in both procedure. Ultimately the study did not show any significant difference between either group. J Shaheed Suhrawardy Med Coll, December 2020, Vol.12(1); 45-49

scholarly journals Evaluation of efficacy and tolerability of nitrofurantoin versus ciprofloxacin in patients of urinary tract infection: a comparative study

2017 ◽  
Vol 6 (11) ◽  
pp. 2690
Author(s):  
Rajneet Kaur ◽  
Vijay Kumar ◽  
Harjinder Singh ◽  
Geeta Walia ◽  
Arshiya Sehgal
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Comparative Study ◽  
Urine Culture ◽  
Post Treatment ◽  
E Coli ◽  
Group I ◽  
Significant Difference ◽  
Group Ii

Background: UTIs are one of the most common infectious diseases encountered in out-patient departments on day to day basis. Nitrofurantoin and Ciprofloxacin are most commonly used antibiotics in the treatment of UTI. The present study was done to compare the efficacy and tolerability of nitrofurantoin and ciprofloxacin in patients of urinary tract infection.Methods: This prospective, open, randomized, parallel group, comparative study was conducted on 60 patients presenting with acute/uncomplicated or recurrent urinary tract infection in the outpatient Department of Urology, Rajindra Hospital attached to Govt. Medical College, Patiala, Punjab. They were divided into two groups, Group I and Group II of 30 cases each. Group I patients were put on Nitrofurantoin and Group II patients were put on Ciprofloxacin. Initially 100 patients were enrolled but only those who showed growth of uropathogens on baseline urine culture or those who completed the treatment were included in the study. The primary outcome measure was microbiological eradication on post treatment urine culture.Results: The age range of the patients in Group I and Group II was 19 to 68 years (43.40±14.58 years) and 20-60 years (39.77±13.49 years) respectively. The total no. of males and females who participated in this study were 32 (53.33%) and 28 (46.66%) respectively. The most common uropathogen associated with uncomplicated UTI was E. coli (80%), other organisms detected were Klebsiella species (16.67%), Staphylococcus aureus (3.33%) and Providencia (3.33%). Post treatment urine culture results showed significant difference between two groups, 5 patients (16.67 %) in case of Group I and 14 patients (46.67%) in case of Group II showed growth of micro-organisms post treatment. P-value comes out to be 0.017 which is significant.Conclusions: In this era of super bugs, nitrofurantoin is more efficacious than ciprofloxacin in the treatment of UTI. E. coli was found to be major organism causing UTI. Ciprofloxacin is less effective due to increasing antibiotic resistance among uropathogens. Both the drugs were well tolerated, no major significant adverse effects were encountered.

Kinetics of erythropoiesis. A comparison of response to anemia induced by phenylhydrazine and by blood loss

1959 ◽  
Vol 197 (4) ◽  
pp. 761-764 ◽  
Author(s):  
Clement A. Finch ◽  
Mary Lu Hanson ◽  
Dennis M. Donohue
Keyword(s):  
Blood Loss ◽  
Normal Animal ◽  
Red Cell ◽  
Group Iii ◽  
Quantitative Measurements ◽  
Group I ◽  
Group Ii ◽  
Kinetics Of ◽  
Removal Group ◽  
Made In

Quantitative measurements of the erythron were made in rabbits. Anemia was produced by red cell removal ( group I), hemolysis from phenylhydrazine ( group II) and red cell removal with replacement by nonviable erythrocytes ( group III). Young red cells, including nucleated and reticulated cell forms, totaled 1.67 x 1010 cells in the normal animal. In anemic animals, by the 3rd day this had increased to 3.59 x 1010 ( group I) and 3.68 ( group II). By the 6th day, average values were 7.24 ( group I) and 7.1 ( group II). There was a greater proportion of young cells in the nucleated form in group I as compared with group II. The addition of nonviable cells ( group III) did not augment erythropoiesis in bled animals. A reticulocyte shift from marrow to circulating blood, proportionate to the degree of anemia, was observed. These studies indicate an augmentation of the rate of erythropoiesis to about three times normal. There was no evidence that products of red cell destruction influence the rate of erythropoiesis.

scholarly journals Termination of mid-trimester pregnancies: misoprostol versus concurrent weighted Foley catheter and misoprostol

F1000Research ◽  
2012 ◽  
Vol 1 ◽  
pp. 36 ◽  
Author(s):  
Ayman Shabana ◽  
Hesham Salah ◽  
Mohamed Kandil ◽  
Emad Soliman ◽  
Dalia Morsi
Keyword(s):  
Side Effects ◽  
Foley Catheter ◽  
University Hospital ◽  
Obstetrics And Gynecology ◽  
Group I ◽  
Significant Difference ◽  
Group Ii ◽  
Vaginal Misoprostol ◽  
Foley’S Catheter

Objective: To investigate whether the use of a weighted trans-cervical fluid-filled Foley’s catheter would improve the effectiveness of 400µg vaginal misoprostol regimen in terminating mid-trimester pregnancies.Methods: This study was conducted at the department of Obstetrics and Gynecology, Menofyia University Hospital in Egypt. Fifty eligible primigravidae were allocated into 2 groups. Termination was carried out in group I using vaginal misoprostol while in group II, a weighted fluid-filled intra-uterine Foley’s catheter was inserted and a similar misoprostol regimen was followed as in group I.Results:The combined group showed shorter induction to termination interval (15.6 ± 4.9 versus 21.9 ± 5.4 hours; P<0.05). There was no significant difference in the occurrence of side effects between the groups.Conclusion: A combination of a weighted Foley’s catheter and 400µg of vaginal misoprostol every 4 hours is more effective than misoprostol alone in terminating mid-trimester gestations.

scholarly journals Association Between Early Idiopathic Neonatal Jaundice and Urinary Tract Infections

2017 ◽  
Vol 11 ◽  
pp. 117955651770111 ◽  
Author(s):  
Murat Özcan ◽  
S Ümit Sarici ◽  
Yüksel Yurdugül ◽  
Melis Akpinar ◽  
Demet Altun ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Neonatal Jaundice ◽  
Urine Culture ◽  
Neonatal Hyperbilirubinemia ◽  
Serum Total Bilirubin ◽  
Group I ◽  
Group Ii ◽  
Tract Infections

Background and purpose: Etiologic role, incidence, demographic, and response-to-treatment characteristics of urinary tract infection (UTI) among neonates, its relationship with significant neonatal hyperbilirubinemia, and abnormalities of the urinary system were studied in a prospective investigation in early (≤10 days) idiopathic neonatal jaundice in which all other etiologic factors of neonatal hyperbilirubinemia were ruled out. Patients and methods: Urine samples for microscopic and bacteriologic examination were obtained with bladder catheterization from 155 newborns with early neonatal jaundice. Newborns with a negative urine culture and with a positive urine culture were defined as group I and group II, respectively, and the 2 groups were compared with each other. Results: The incidence of UTI in whole of the study group was 16.7%. Serum total and direct bilirubin levels were statistically significantly higher in group II when compared with group I ( P = .005 and P = .001, respectively). Decrease in serum total bilirubin level at the 24th hour of phototherapy was statistically significantly higher in group I compared with group II ( P = .022). Conclusions: Urinary tract infection should be investigated in the etiologic evaluation of newborns with significant hyperbilirubinemia. The possibility of UTI should be considered in jaundiced newborns who do not respond to phototherapy well or have a prolonged duration of phototherapy treatment.

scholarly journals Effect of different short term synchronization protocols on estrus and fertility in non-pregnant ewes during the breeding season

2019 ◽  
Vol 70 (2) ◽  
pp. 1461
Author(s):  
Ş DURSUN
Keyword(s):  
Breeding Season ◽  
Pregnancy Loss ◽  
Pregnancy Rates ◽  
The Other ◽  
Short Term ◽  
Group Iii ◽  
Group I ◽  
Group Ii ◽  
Removal Group ◽  
Group 1

The aim of this study was to investigate the efficacy of different short term synchronization protocols on estrus and pregnancy rates in merino ewes that had not become pregnant after at least three matings during the breeding season. Three different protocols were used as follows: Group I: Ewes (n=30) were inserted intravaginal progesterone sponge (florogestan asetate; 30 mg) for 6 days plus PGF2α (125 μg, i.m.) at the time of sponge removal, Group II: Ewes (40) were treated same as in group 1 plus eCG (250 IU, i.m.) at time of sponge removal, and Group III: Ewes (n=38) were only injected with PGF2α at the same time with the ewes in the other two groups. Estrus was detected by rams (n=4), 24 hours after PGF2α and ewes detected in estrus were mated. Ten rams were used for mating. Pregnancy was diagnosed 60 days after mating by ultrasonography. Estrus, conception and pregnancy rates were: for Group I 100%, 73.3% and 73.3%, for Group II 92.5%, 89.2% and 82.5% and for Group III 81.6%, 100% and 81%. In Group III, pregnancy loss after pregnancy diagnosis was significantly higher (35.4%) compared with the other groups (Group I: 13.6% and Group II: 15%).

Ultrastructural Lesions Produced by Alcohol and Sucrose in the Heart and Liver of C57BL Mice

1970 ◽  
Vol 28 ◽  
pp. 208-209
Author(s):  
K.K. SEKHRI ◽  
C.S. ALEXANDER ◽  
H.T. NAGASAWA
Keyword(s):  
Osmium Tetroxide ◽  
Male Mice ◽  
Alcohol Group ◽  
Group Iii ◽  
Group I ◽  
C57bl Mice ◽  
Group Ii

C57BL male mice (Jackson Lab., Bar Harbor, Maine) weighing about 18 gms were randomly divided into three groups: group I was fed sweetened liquid alcohol diet (modified Schenkl) in which 36% of the calories were derived from alcohol; group II was maintained on a similar diet but alcohol was isocalorically substituted by sucrose; group III was fed regular mouse chow ad lib for five months. Liver and heart tissues were fixed in 2.5% cacodylate buffered glutaraldehyde, post-fixed in 2% osmium tetroxide and embedded in Epon-araldite.

Heterogeneity and Immunochemical Properties of Anti-β2-glycoprotein I Autoantibodies

1998 ◽  
Vol 80 (09) ◽  
pp. 393-398 ◽  
Author(s):  
V. Regnault ◽  
E. Hachulla ◽  
L. Darnige ◽  
B. Roussel ◽  
J. C. Bensa ◽  
...  
Keyword(s):  
Fluid Phase ◽  
Anticardiolipin Antibodies ◽  
Dual Reactivity ◽  
Group Iii ◽  
Important Group ◽  
Epitope Specificity ◽  
Glycoprotein I ◽  
Group I ◽  
Group Ii ◽  
Sufficient Concentration

SummaryMost anticardiolipin antibodies (ACA) associated with antiphospholipid syndrome (APS) are directed against epitopes expressed on β2-glycoprotein I (β2GPI). Despite a good correlation between standard ACA assays and those using purified human β2GPI as the sole antigen, some sera from APS patients only react in the latter. This is indicative of heterogeneity in anti-β2GPI antibodies. To characterize their reactivity profiles, human and bovine β2GPI were immobilized on γ-irradiated plates (β2GPI-ELISA), plain polystyrene precoated with increasing cardiolipin concentrations (CL/β2GPI-ELISA), and affinity columns. Fluid-phase inhibition experiments were also carried out with both proteins. Of 56 selected sera, restricted recognition of bovine or human β2GPI occurred respectively in 10/29 IgA-positive and 9/22 IgM-positive samples, and most of the latter (8/9) were missed by the standard ACA assay, as expected from a previous study. Based on species specificity and ACA results, IgG-positive samples (53/56) were categorized into three groups: antibodies reactive to bovine β2GPI only (group I) or to bovine and human β2GPI, group II being ACA-negative, and group III being ACA-positive. The most important group, group III (n = 33) was characterized by (i) binding when β2GPI was immobilized on γ-irradiated polystyrene or cardiolipin at sufficient concentration (regardless of β2GPI density, as assessed using 125I-β2GPI); (ii) and low avidity binding to fluid-phase β2GPI (Kd in the range 10–5 M). In contrast, all six group II samples showed (i) ability to bind human and bovine β2GPI immobilized on non-irradiated plates; (ii) concentration-dependent blockade of binding by cardiolipin, suggesting epitope location in the vicinity of the phospholipid binding site on native β2GPI; (iii) and relative avidities approximately 100-fold higher than in group III. Group I patients were heterogeneous with respect to CL/β2GPI-ELISA and ACA results (6/14 scored negative), possibly reflecting antibody differences in terms of avidity and epitope specificity. Affinity fractionation of 23 sera showed the existence, in individual patients, of various combinations of antibody subsets solely reactive to human or bovine β2GPI, together with cross-species reactive subsets present in all samples with dual reactivity namely groups III and II, although the latter antibodies were poorly purified on either column. Therefore, the mode of presentation of β2GPI greatly influences its recognition by anti-β2GPI antibodies with marked inter-individual heterogeneity, in relation to ACA quantitation and, possibly, disease presentation and pathogenesis.

Treatment of venous leg ulcers with sulodexide

Phlebologie ◽  
2003 ◽  
Vol 32 (05) ◽  
pp. 115-120 ◽  
Author(s):  
A. Franek ◽  
H. Koziolek ◽  
M. Kucharzewski
Keyword(s):  
Pharmacological Treatment ◽  
Healing Process ◽  
Leg Ulcers ◽  
Venous Ulceration ◽  
Venous Leg Ulcers ◽  
Group I ◽  
Group Ii

SummaryAim: The study of the influence of sulodexide in the treatment of venous leg ulcers. Patients and method: 44 patients with chronic venous ulceration were randomly divided into two groups. Group I: 21 patients (ulceration area: 12.7-18.9 cm2), Group II: 23 patients (ulceration size: 12.1-20.3 cm2). Both groups were treated by using Unna’s boot. This dressing was changed every seven days until the ulcer had healed. Additionally, the patients in group II received the systemic pharmacological treatment with sulodexide. Results: After 7 weeks of treatment ulcers of seven patients (35%) from group I had healed, and 3 weeks later the ulceration of two more patients had healed completely. After further 7 weeks the ulcers of 12 patients had healed completely. Whereas in group II after 7 weeks of treatment ulceration of 16 (70%, p <0.05) patient had healed completely and after further 3 weeks the ulcers of the remaining 7 patients had healed, too. Conclusion: The use of sulodexide in patients with chronic venous leg ulcers accelerates the healing process.

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