scholarly journals A rare case report of primary renal squamous cell carcinoma

Author(s):  
Sneha P. Chavarkar ◽  
Amit K. Agrawal ◽  
Alok C. Shrivastava ◽  
Anuradha V. Shrikhande

Primary renal squamous cell carcinoma is a very rare entity. Only few cases are reported in the world literature. Most of the patients present at a late stage resulting in poor prognosis. We report a 44 year old female who presented with a history of lump in right flank accompanied with a dull intermittent pain for 2 months duration which intensified in the last 15 days. Antecedent risk factors like renal calculi, analgesic use were absent. Computed Tomography (CT) examination revealed a mass arising from the superior pole of kidney with extension to the posterior segment of liver. Histopathology following nephrectomy showed histological features of well differentiated squamous cell carcinoma.

2019 ◽  
Vol 04 (11) ◽  
pp. 821-824
Author(s):  
Vijaya Lakshmi Muram Reddy ◽  
Penchala Reddy Muram Reddy ◽  
Shanthi Vissa ◽  
Mohan Rao Nandam ◽  
Syam Sundara Rao Byna ◽  
...  

2018 ◽  
Vol 46 (8) ◽  
pp. 3417-3421 ◽  
Author(s):  
Qi Wu ◽  
Zhaoping Chu ◽  
Hua Han ◽  
Suning Bai ◽  
Wenfei Wu ◽  
...  

Primary endometrial squamous cell carcinoma is an extremely rare tumor that tends to occur in postmenopausal women. We report on a 33-year-old woman who presented with a history of irregular vaginal bleeding for more than 2 years, and a vaginal mass for more than 1 month. Biopsy of the vaginal mass revealed an invasive poorly differentiated squamous cell carcinoma. The patient underwent radical hysterectomy, bilateral salpingo-oophorectomy, omentectomy, pelvic lymph node dissection, peritoneal sampling and vaginal tumor resection. On the basis of her medical history, auxiliary examination and postoperative pathology, the patient was diagnosed with stage IV endometrial squamous cell carcinoma. The patient was followed-up regularly and remained in good condition.


2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Hafiz Muhammad Sharjeel Arshad ◽  
Aleida Rodriguez ◽  
Faten Suhail

Background. The Syndrome of Inappropriate Antidiuretic Hormone (SIADH) is considered to be the most common cause of euvolemic hyponatremia. The most common malignancy associated with SIADH is small cell lung cancer. We present a rare case of a patient with SIADH secondary to well differentiated squamous cell carcinoma of the naso-oropharynx.Case. A 46-year-old Caucasian woman presented to emergency department with four-week history of progressive dysphagia. On examination, she was found to have a pharyngeal mass. CT scan and MRI of neck confirmed a mass highly suspicious of carcinoma. Patient’s serum sodium level decreased to 118 mEq/L and other labs including serum and urine osmolality confirmed SIADH. She was started on fluid restriction and oral sodium tablets which gradually improved her serum sodium levels. Biopsy confirmed diagnosis of squamous cell carcinoma of pharynx.Conclusion. SIADH can be caused by squamous cell carcinoma. Appropriate management includes fluid restriction.


2012 ◽  
Vol 3 (2) ◽  
pp. 34-36 ◽  
Author(s):  
SM Badruddoza ◽  
Shahnaz Pervin

Primary renal squamous cell carcinoma is a very rare tumour. Only a few cases have been reported in world literature. Here we report a case with renal squamous cell carcinoma. The patient presented with flank pain, fever and vomiting. In ultrasonography, renal mass was detected and after nephrectomy followed by histopathological examination, it was diagnosed as   squamous cell carcinoma. There was no evidence of renal calculi or other predisposing factors.  This report highlights the rarity of the tumour.   DOI: http://dx.doi.org/10.3329/akmmcj.v3i2.11692   AKMMC J 2012: 3(2): 34-36  


2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Makama Baje Salihu ◽  
Stephen Yusuf ◽  
Adogu Ibrahim Ogere

Squamous cell carcinoma of the kidney is a rare malignancy of the upper urothelium usually seen at advanced stage due to delay in diagnosis and or presentation. Mostly seen in patients with history of untreated chronic urolithiasis, chronic renal infection or analgesic abuse. A 46-years-old man who presented with right recurrent loin pain that radiates to the right groin of 10 years duration which worsened 2 weeks prior to presentation, he had history of recent haematuria, right loin pain, significant weight lost with associated history of untreated right renal calculi. General examination was not remarkable, ultrasound scan revealed a huge right renal mass with calculi. Intravenous urogram showed a non-functioning right kidney. Right radical nephrectomy was done, cut surface showed replacement of the renal parenchyma with greyish white tumour with stones in some blind calyxes. Histology revealed moderately differentiated squamous cell carcinoma of the right kidney. We report a case of moderately differentiated squamous cell carcinoma of the right kidney in a patient with a long history of untreated renal calculi. High index of suspicion for malignancy should be kept when seeing patients with long history of untreated renal calculi.


Author(s):  
Nilesh H. Mahajan ◽  
Asha M. ◽  
Vinay Kumar Vijayendra ◽  
Vijayendra Honnurappa

<p class="abstract">Squamous cell carcinoma of middle ear is a rare entity. We present a case of 77 year old male, with squamous cell carcinoma of middle ear. Patient presented with blood tinged otorrhoea. Oto-endoscopy examination revealed a soft tissue lesion in middle ear which bled on touch. Histopathological study of this soft tissue lesion gave a diagnosis of well differentiated squamous cell carcinoma. Radical clearance of the tumour achieved after removal of the malleus and incus. Tumour was seen extending into the eustachian tube orifice and it was removed in toto. Uderlying bone was ablated using diode laser to confirm the radical clearance. Later patient was given radiotherapy 6 weeks after surgery to allow the healing of the operative site. The objective to report this case was to emphasize the importance of early diagnosis and prompt treatment for a better survival. Long standing history of ear discharge with soft tissue lesion bleeding on touch should always be evaluated by histopathological study to exclude malignancy.</p>


2021 ◽  
Vol 14 (1) ◽  
pp. e236477
Author(s):  
Subhash Soni ◽  
Poonam Elhence ◽  
Vaibhav Kumar Varshney ◽  
Sunita Suman

Squamous cell carcinoma (SCC) of the ampulla of Vater is a rare pathology and only few cases are reported in the literature. With limited experience of primary SCC in the ampulla of Vater, its biological behaviour, prognosis and long-term survival rates are not well known. A 38-year-old woman presented with a history of painless progressive jaundice for which self-expending metallic stent was placed 3 years back. She was evaluated and initially diagnosed as probably periampullary adenocarcinoma. She underwent pancreaticoduodenectomy and histopathology with immunohistochemistry was suggestive of SCC of ampulla of Vater. She received adjuvant chemotherapy and doing well with no recurrence after 1 year of follow-up. In conclusion, SCC of the ampulla is an unusual pathology that should be kept as a differential diagnosis for periampullary tumours. Surgical treatment with curative intent should be performed whenever feasible even in the setting of bulky tumour to improve the outcome.


2019 ◽  
Vol 7 ◽  
pp. 2050313X1984735 ◽  
Author(s):  
Catherine F Roy ◽  
Simon F Roy ◽  
Feras M Ghazawi ◽  
Erica Patocskai ◽  
Annie Bélisle ◽  
...  

We present a case of a 64-year-old man who presented with a rapidly growing tumor in the left buttock and intergluteal cleft area, which was affected by hidradenitis suppurativa. The patient was on tumor necrosis factor-alpha inhibitors for hidradenitis suppurativa for 2 years prior to the development of the mass. Initial biopsy of the mass showed a well-differentiated squamous cell carcinoma with spindle cells and positive epithelial immunomarkers. Subsequent excisional biopsy of the tumor showed an infiltrating poorly differentiated squamous cell carcinoma composed of islands of atypical sarcomatoid spindle cells. Squamous cell carcinoma arising in hidradenitis suppurativa is a rare complication which may occur secondary to chronic inflammation and epidermal hyperproliferation in hidradenitis suppurativa–affected areas.


2021 ◽  
pp. 912-917
Author(s):  
Zainub Ajmal ◽  
Abdul Moiz Khan ◽  
Lezah McCarthy ◽  
Allison Lupinetti ◽  
Syed Mehdi

Leiomyosarcoma (LMS) of the trachea is an extremely rare malignancy with only a few reported cases in English literature. As such the diagnosis can be frequently missed or delayed. We present a case of a 69-year-old male who underwent tracheostomy for airway obstruction secondary to glottic squamous cell carcinoma and treated definitely with radiation therapy. Subsequently, the patient developed LMS of the tracheostomy site. The case further details multiple risk factors that could contribute to development of LMS including radiation exposure, prior malignancy, and chronic inflammation. These risk factors have been well established for LMS in other sites but less so in the head and neck region, which is the subject of our discussion. We also review the current guidelines for head and neck as well as limb sarcomas and discussed role of surgery or radiation and their accompanying challenges in management of this rare malignancy.


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