scholarly journals Prevalence of Helicobacter pylori infection among dyspepsia patients with mucosal lesion in tertiary care hospital

2018 ◽  
Vol 5 (6) ◽  
pp. 2264
Author(s):  
Amit S. Yadav ◽  
Umesh B. Kulkarni ◽  
Bharat C. Kumar ◽  
Unmesh V. Takalkar
Keyword(s):  
Helicobacter Pylori ◽  
Biopsy Specimen ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Exclusion Criteria ◽  
Mucosal Lesions ◽  
Non Ulcer Dyspepsia ◽  
H Pylori ◽  
Curved Rod

Background: Helicobacter pylori (H. pylori), a curved rod shaped bacteria, is found to be associated with acid peptic disease patients, more in ulcer than non-ulcer, leading to a belief that H. pylori plays a role in its etiopathogenesis. In this study we examine the prevalence of H. pylori infection among dyspepsia patients with mucosal lesion.Methods: 300 patients of dyspepsia were enrolled in the study as per inclusion/exclusion criteria for a period of eight months. Enrolled patients were subjected to upper gastro-intestinal endoscopy and findings were recorded. Biopsy specimen taken from mucosal lesions were immediately inoculated on ‘RUT dry kit’ to test for H. pylori infection.Results: 234 out of 300 patients (78%) were found to be positive for H. pylori infection. The incidence of H. pylori infection was higher in patients with ulcer dyspepsia (88.46%) when compared to the patients with non-ulcer dyspepsia (72.44%).Conclusions: Prevalence of H. pylori infection was high and was found to have an association with ulcer dyspepsia allowing us to conclude that H. pylori may have a role in its etiopathogenesis.

scholarly journals Frequency of H. Pylori infection in children with recurrent abdominal pain at a Tertiary Care Hospital.

2020 ◽  
Vol 27 (02) ◽  
pp. 237-241
Author(s):  
Asim Khurshid ◽  
Shahid Ishaq ◽  
Mushtaq Ahmad
Keyword(s):  
Helicobacter Pylori ◽  
Drinking Water ◽  
Disease Duration ◽  
Family Income ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Recurrent Abdominal Pain ◽  
Male Gender ◽  
Care Hospital ◽  
H Pylori

Objectives: Recurrent abdominal pain (RAP) impacts quality of life of the children. RAP also hampers education and physical activity of the children. Current study was aimed to find out the frequency of Helicobacter pylori in children with RAP in our tertiary care hospital. Study Design: Descriptive, cross-sectional study. Setting:  Department of Pediatric Medicine, Nishtar Hospital, Multan, Period: From 27-12-2017 to 26-06-2018. Material & Methods: A total of 185 patients suffering from RAP, aged 2-12 years, with a disease duration > 3 months, were enrolled. Age of the children, gender, duration of illness, number of episodes of pain, maternal literacy, family income, residential status, source of drinking water and h.pylori infection were calculated in these children. Post stratification chi-square test was applied to see its effect on H. Pylori infection. Results: Of these 185 study cases, 101 (54.6 %) were male patients while 84 (45.4%) were female. Mean age of our study cases was 7.57 ± 1.93 years. Of A total of 95 (51.4%) children belonged to rural areas and 90 (48.6 %) to urban areas. Helicobacter pylori infection was noted in 103 (55.7%) of our study cases. When helicobacter pylori  was stratified with regards to study variables, male gender, age < 8 years, monthly family income <Rs. 35000, source of drinking water as Hand Pump and disease duration < 6 months turned out to be statistically significant (P value < 0.05). Conclusion: Frequency of H.pylori was high in children with RAP. Helicobacter pylori was significantly associated with male gender, younger age, poor socioeconomic status, source of drinking water and disease duration.

scholarly journals Frequency of Helicobacter Pylori Infection in the Local Population Presenting with Dyspeptic Symptom

2021 ◽  
Vol 15 (6) ◽  
pp. 1692-1694
Author(s):  
Muhammad Zarrar ◽  
Shahzad Memon ◽  
Kashif Ali ◽  
Arsalan Badar ◽  
Yar Muhammad ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Tertiary Care Hospital ◽  
Local Population ◽  
Tertiary Care ◽  
Antibody Test ◽  
Helicobacter Pylori Infection ◽  
Dyspeptic Symptom ◽  
Care Hospital ◽  
Iga Antibody ◽  
H Pylori

Objectives: To determine the frequency of Helicobacter pylori infection in the local population presenting with dyspeptic symptom report to a tertiary care hospital of Nawabshah. Methodology: This cross-sectional study took place at department of medicine, Peoples Medical College and Hospital Nawabshah; during six months, form August 2015 to February 2016. A total of 115 patients with dyspeptic symptoms with upper abdominal disorders such as discomfort and pain, nausea, fullness, bloating, heartburn, anorexia, belching and regurgitation were included. After conducting detailed clinical examination and history, patients were subjected to relevant examinations, i.e. Blood antibody test (IgA antibody test), for H. pylori and venous blood was drawn. All the information was collected in the proforma. Results: The patients’ average age was 30.92±6.10 years. There were 66(57.4%) male cases and 49(42.6%) female cases. Helicobacter pylori (H. pylori) infection was observed to be frequent (60% cases) among both genders. Conclusion: In conclusion, the present results confirm that the frequency of patients suffering from helicobacter pylori infection was quite high in local population at tertiary care hospital, Nawabshah. Strategies could be developed at an earlier stage and prompt treatment may reduce the morbidity. Key Words: Dyspepsia, Helicobacter pylori, IgA antibody test

scholarly journals Frequency of H. Pylori infection in children with recurrent abdominal pain at a Tertiary Care Hospital.

2020 ◽  
Vol 27 (02) ◽  
pp. 237-241
Author(s):  
Asim Khurshid ◽  
Shahid Ishaq ◽  
Mushtaq Ahmad
Keyword(s):  
Helicobacter Pylori ◽  
Drinking Water ◽  
Disease Duration ◽  
Family Income ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Recurrent Abdominal Pain ◽  
Male Gender ◽  
Care Hospital ◽  
H Pylori

Objectives: Recurrent abdominal pain (RAP) impacts quality of life of the children. RAP also hampers education and physical activity of the children. Current study was aimed to find out the frequency of Helicobacter pylori in children with RAP in our tertiary care hospital. Study Design: Descriptive, cross-sectional study. Setting:  Department of Pediatric Medicine, Nishtar Hospital, Multan, Period: From 27-12-2017 to 26-06-2018. Material & Methods: A total of 185 patients suffering from RAP, aged 2-12 years, with a disease duration > 3 months, were enrolled. Age of the children, gender, duration of illness, number of episodes of pain, maternal literacy, family income, residential status, source of drinking water and h.pylori infection were calculated in these children. Post stratification chi-square test was applied to see its effect on H. Pylori infection. Results: Of these 185 study cases, 101 (54.6 %) were male patients while 84 (45.4%) were female. Mean age of our study cases was 7.57 ± 1.93 years. Of A total of 95 (51.4%) children belonged to rural areas and 90 (48.6 %) to urban areas. Helicobacter pylori infection was noted in 103 (55.7%) of our study cases. When helicobacter pylori  was stratified with regards to study variables, male gender, age < 8 years, monthly family income <Rs. 35000, source of drinking water as Hand Pump and disease duration < 6 months turned out to be statistically significant (P value < 0.05). Conclusion: Frequency of H.pylori was high in children with RAP. Helicobacter pylori was significantly associated with male gender, younger age, poor socioeconomic status, source of drinking water and disease duration.

scholarly journals Serum ferritin and iron profile in helicobacter pylori infected young adult male reporting at a tertiary care hospital

2019 ◽  
Vol 26 (06) ◽  
Author(s):  
Arshad ◽  
Suresh Kumar ◽  
Bilawal Hingorjo ◽  
Nathumal Maheshwari ◽  
Rewachand ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Young Adult ◽  
Adult Male ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Specific Antigen ◽  
Care Hospital ◽  
Young Adult Male ◽  
H Pylori ◽  
Iron Profile

Objectives: Determination of serum ferritin and iron profile in Helicobacter pylori infected young adult male reporting at a tertiary care hospital of Sindh. Study Design: Case control study. Study Setting & Duration: Department of Medicine, Layari General Hospital Shaheed Muhtrama Benazir Bhutto Medical College from January 2015 to February 2016. Study Subjects and Methods: 100 cases (H. pylori stool specific antigen positive) and 100 controls (H pylori negative) were selected and studied. 5 ml blood was collected in a disposable syringe by venesection. 2 ml was put in EDTA tubes and 3 ml was centrifuged (3000 x rpm for 10 minutes). Sera were used for the estimation of iron profile. Elisa assay method (Fortress diagnostics) detected the H. pylori stool specific antigen (HpSA). Data was analyzed on SPSS 22.0 (USA) at 95% CI (P≤ 0.05). Results: Age of control and cases was noted 35.48±4.79 and 33.60±3.96 years (P=0.053). Hb, Hct and RBC counts were low in cases (P=0.0001) significantly. Serum iron (Fe++), ferritin and TIBC in controls and cases were noted 152.72±6.08 and 118.79±43.30 μg/dl, 394.34±136.50 and 529.87±101.0 ng/dl, & 140.80±19.99 and 130.88±28.46 μg/dl respectively (P=0.0001) (Table-I). Conclusion: Helicobacter pylori infection causes iron malabsorption as detected by serum iron and ferritin and total iron binding capacity in young adult male.

scholarly journals Helicobacter pylori among the cases of gastritis: a one year study at a tertiary care hospital of South India

2019 ◽  
Vol 6 (12) ◽  
pp. 4294
Author(s):  
Ayathu V. S. Sai Mahesh ◽  
Shyam Sundar Tandri
Keyword(s):  
Helicobacter Pylori ◽  
Tertiary Care Hospital ◽  
Histopathological Examination ◽  
Demographic Data ◽  
Tertiary Care ◽  
Rapid Urease Test ◽  
Care Hospital ◽  
Urease Test ◽  
H Pylori ◽  
One Year

Background: Gastritis is one of the commonest clinical conditions encountered by a physician. The most common cause is said to be infection with Helicobacter pylori. The present study was aimed to diagnose the prevalence of H. pylori infection among the cases of gastritis and its correlation with histopathological findings and associated rapid urease test.Methods: A one year prospective study at a tertiary care hospital was conducted and all cases of gastritis were included and socio demographic data, clinical complaints and duration were noted. Endoscopy was performed on all cases. Biopsy was performed histopathological examination with staining and graded by Houston-updated Sydney system. Rapid urease test was performed and findings noted.Results: 325 cases with 215 male and 110 female cases were included. 26.15% were in age group of more than 60 years and number of cases increased with age. Mean age of study participants was 39.12±2.8 years and heart burn was the common complaint in the study cases. 81.54% of the cases revealed endoscopic gastritis on endoscopy and hyperaemia was commonest. 83.69% were positive by rapid urease test. Rapid urease test is more sensitive than histological staining in confirmation of H. pylori infection.Conclusions: To conclude on the present study, the prevalence of H. pylori infection is on a global rise and appropriate measures to reduce the prevalence is quite an urgent necessity. Histopathological interpretation of gastric biopsies is a reliable indicator of H. pylori infection as well as gastritis grading according to the Sydney grading system.

scholarly journals Epidemiology of upper gastrointestinal bleeding and Helicobacter pylori infection: review of 3,488 Thai patients

2017 ◽  
Vol 9 (1) ◽  
pp. 87-93
Author(s):  
Sakolwan Suchartlikitwong ◽  
Kamolyut Lapumnuaypol ◽  
Rungsun Rerknimitr ◽  
Duangporn Werawatganon
Keyword(s):  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Helicobacter Pylori Infection ◽  
Exclusion Criteria ◽  
Common Causes ◽  
Mucosal Lesions ◽  
H Pylori ◽  
Upper Gastrointestinal

Abstract Background The current epidemiology of upper gastrointestinal bleeding (UGIB) in Thailand is poorly understood and the reported prevalence of Helicobacter pylori infection is outdated. Objectives To investigate the etiologies of UGIB and prevalence of H. pylori infection in Thailand, including its association with UGIB. Methods We retrieved information regarding patients attending the endoscopic unit of King Chulalongkorn Memorial Hospital from June 2007 to January 2013. A database search using keywords “upper gastrointestinal bleeding” and “iron deficiency” was used. From 4,454 diagnoses, after exclusion criteria, 3,488 patients (2,042 male (58.5%) and 1,446 female (41.5%); mean age 63.3 ± 15.94 years, range 13–103 years) were included. Results The three most common causes of UGIB were peptic ulcer (38.2%), nonulcer-mucosal lesions (23.4%), and esophageal-related causes (20.4%). The 5 year-incidence of H. pylori was 25%–30%. The overall prevalence was 27%. The prevalence of H. pylori infection was found to decrease with age from 43.8% at <40 years to 21.7% at >79 years old. H. pylori infection was significantly associated with duodenal and gastroduodenal ulcers. Cirrhosis and nonulcer-mucosal lesions were significantly unrelated to H. pylori infection. Patients with concurrent cirrhosis with peptic ulcer were found to be negative for H. pylori infection. Conclusion Peptic ulcer is the leading cause of UGIB in Thailand. However, its incidence is declining. Patients who presented to hospital with UGIB were older, compared with those a decade ago. H. pylori infection plays an important role in UGIB and its incidence was stable during the past 5 years.

scholarly journals Prevalence and risk factors of Helicobacter pylori infections in the patients suffering from acid-peptic disease at tertiary care center, Gujarat, India

2018 ◽  
Vol 5 (5) ◽  
pp. 1250
Author(s):  
Anjali K. Kukreja ◽  
Himani B. Pandya ◽  
Santosh Kumar
Keyword(s):  
Risk Factors ◽  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Abdominal Pain ◽  
Prevalence Rate ◽  
Tertiary Care ◽  
Chili Pepper ◽  
Care Hospital ◽  
Spicy Food ◽  
H Pylori

Background: Helicobacter pylori (H. pylori) infection is a medical encumber especially in the developing countries, ranging from acute inflammation to malignancy. The study is intended to explore the prevalence of H. pylori infection and also to compute its associated risk factors.Methods: Sixty two (n=62) symptomatic patients attending the tertiary care hospital, were included in the study. Two antral biopsies collected from each patient were subjected to rapid urease test and Gram staining. IgG antibodies were detected by rapid test based on the principle of Immunochromatography. To evaluate the risk factors, various determinants were asked to each patient in the form of questionnaire. Statistical analysis was done using Fisher exact test. P value < 0.05 was considered significant.Results: Prevalence rate of H. pylori infection was 24.19 % (15/62). More than half (53%) of the infected patients had complained of persistent burning abdominal pain. Prevalence rate was found highest in the patients suffering from peptic ulcer disease (66.6%, P=0.0237). Consumption of unfiltered water (P=0.007, Odd Ratio (OR)-1.06), eating spicy food, meat, fish and chili pepper (P=0.052, OR-1.01) was found the major risk factors. Addictive habits of either smoking/alcohol/tobacco (P=0.904) were not associated with infection.Conclusions: Prevalence of H. pylori infection was found low comparatively and was mainly associated with symptom of persistent burning abdominal pain and peptic ulcer. Use of unfiltered water, spicy food, chili pepper and meat undoubtedly increase the risk of acquiring H. pylori infection. Addictive habits were not significantly associated with infection.

Sign in / Sign up

Export Citation Format

Share Document