scholarly journals Investigating the prolongation of blood transfusion frequency in thalassemic children by omega 3 fatty acid and protein supplementations through milk

2021 ◽  
Vol 8 (1) ◽  
pp. 17
Author(s):  
Amol Kumar ◽  
Preeti Doshi ◽  
Ramdas Dahiphale ◽  
Ansh Chaudhary ◽  
Bhupendra Chaudhary
Keyword(s):  
Fatty Acid ◽  
Blood Transfusion ◽  
Screening Program ◽  
Genetic Disorder ◽  
Tertiary Care ◽  
Hemoglobin Level ◽  
Blood Transfusions ◽  
Care Hospital ◽  
Omega 3 ◽  
Omega 3 Fatty Acid

<p class="abstract"><strong>Background:</strong> Thalassemia is an inherited genetic hemoglobin disorder wherein, afflicted child is born when both parents are carriers for defective alpha or beta hemoglobin gene. The thalassemias are the most common genetic disorder on a worldwide basis. The requirement of frequent blood transfusions in these patients pose a substantial burden on the health care system.</p><p class="abstract"><strong>Methods:</strong> A prospective observational study was conducted across 6 months (July 2018-December 2018) in a tertiary care hospital, Pune. The present study included 30 registered patient &amp; their past 6 months record of blood transfusion (esp frequency), previous hemoglobin levels, height &amp; weight. All these parameters were compared 6 months after supplementation with Omega 3 fatty Acids &amp; proteins.</p><p class="abstract"><strong>Results:</strong> Total 16 of 28 patient showed that the average durations between two blood transfusions was increased by minimum 01 day to a maximum of 5 days. The average number of blood bag required was less than required blood bags in the period of pre supplementation. 20 of 28 patients showed a rise in hemoglobin level from a range of 0.5 to 1.2 gm/dl.  </p><p class="abstract"><strong>Conclusions: </strong>In a country like India, with the high frequency of hemoglobinopathies, causing increased burden on the society, it is necessary to control the incidence by effective steps. Low cost and easily administered supplementation by omega 3 fatty acid and proteins may reduce the requirement of repeated blood transfusion along with increase in hemoglobin level. Implementation of carrier screening program offering genetic counseling and prenatal diagnosis followed by selective termination of affected cases would help in preventing the disease.</p>

Characteristics and Frequency of Hepatitis C among Children With Β-Thalassemia Visiting Tertiary Care Hospital

2021 ◽  
Vol 15 (10) ◽  
pp. 2576-2577
Author(s):  
Huda Abbas ◽  
Zunaira Javed ◽  
Sadia Bashir ◽  
Wajahat Hussain ◽  
Nadia Tufail ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Blood Transfusion ◽  
Rural Areas ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Blood Transfusions ◽  
Care Hospital ◽  
Cross Sectional ◽  
Safe Blood ◽  
Public And Private Sector

Aim: To find the characteristics and frequency of hepatitis C among children with β-Thalassemia. Methodology: It was a cross sectional type of study conducted in tertiary care hospital of Bahawalpur for a period of 6 months from from January 2021 to June 2021. Sample size was 51 patients. Patients suffering from β-Thalassemia and were undergoing blood transfusions in large amounts were included. Results: β-Thalassemia is more common in Males (67%) than females (33%) with most of the cases detected in the patients who were living in rural areas (61%). Moreover, with the increase in number of transfusions the threat of HCV increases. Conclusion: Blood transfusion is a lifesaving intervention. There is a need to pay an immediate attention towards the bio safety practice in both the public and private sector blood banks. There must be strict rules and regulations for safe blood transfusions in Pakistan. Keywords: Thalassemia; HCV; Blood transfusion; HB electrophoresis

scholarly journals MP15: Blood transfusion in upper gastrointestinal bleeding: evaluating physician practices in the emergency department

CJEM ◽  
2019 ◽  
Vol 21 (S1) ◽  
pp. S47
Author(s):  
J. Stach ◽  
S. Sandha ◽  
M. Bullard ◽  
B. Halloran ◽  
H. Blain ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Tertiary Care ◽  
Blood Transfusions ◽  
Care Hospital ◽  
Current Guideline ◽  
Transfusion Threshold ◽  
Physician Practices ◽  
Upper Gastrointestinal

Introduction: Acute upper gastrointestinal bleeding (UGIB) is a common presentation to emergency departments (ED). Of these patients, 35-45% receive a blood transfusion. Guidelines for blood transfusion in UGIB have been well established, and recommend a hemoglobin (Hb) level below 70 g/L as the transfusion target in a stable patient. There is no consensus on a transfusion threshold for unstable UGIB. There is limited data regarding physician practices in the ED. The aim of our study is to determine the appropriateness, by expert consensus, of blood transfusions in UGIB in a tertiary care hospital ED. Methods: We retrospectively reviewed patients presenting with UGIB to the University of Alberta Hospital ED in 2016. These patients were then screened for blood transfusions. Data were obtained from the patient records. Chart derived data were verified with records obtained from the blood bank. For each patient, the history, vitals, Glasgow Blatchford Score (GBS), relevant labs, and record of blood transfusions were collected and organized into a case summary. Each patient summary was presented individually to a panel of three expert clinicians (2 Gastroenterology, 1 Emergency Medicine), who then decided on the appropriateness of each blood transfusion by consensus. Results: Blood transfusions (data available 395/400) were given to 51% (202/395) of patients presenting with UGIB. Of these, 86% (174/202) were judged to be appropriate. Of the 395 patients, 34% (135/395) had a Hb of &lt;70 g/L. Of these, 93% (126/135) were transfused, and all of these were considered appropriate. 18% (70/395) had a Hb between 71-80. 74% (52/70) of these patients were given blood, and 79% (41/52) were considered appropriate. 13% (50/395) of the patients had a Hb between 81-90, with 28% (14/50) receiving a transfusion. Of these, 36% (5/14) were deemed to be appropriate. 35% (140/395) of patients had a Hb of &gt;90. 7% (10/140) of these received blood. 20% (2/10) were considered appropriate. Conclusion: The panel of expert clinicians judged 86% of the blood transfusions to be appropriate. All transfusions under the recommended guideline of 70 g/L were considered appropriate. In addition, the majority of transfusions above a Hb of 70 g/L were considered appropriate, but 37% were not. Further studies evaluating the feasibility of current guideline recommendations in an ED setting are required. Educational interventions should be created to reduce inappropriate blood transfusions above a Hb 70 g/L.

scholarly journals Knowledge, practice and experiences of parents with a thalassemic child

2017 ◽  
Vol 4 (5) ◽  
pp. 1630 ◽  
Author(s):  
Amit Saxena ◽  
Mumtaz Sharif ◽  
Sadaf Siddiqui ◽  
Swati Singh
Keyword(s):  
Blood Transfusion ◽  
Financial Burden ◽  
Genetic Disorder ◽  
Good Practice ◽  
Tertiary Care ◽  
Thalassemia Major ◽  
Beta Thalassemia ◽  
Care Hospital ◽  
Cross Sectional ◽  
Adequate Knowledge

Background: Thalassaemia is a chronic disorder requiring lifelong transfusions and medications causing emotional and financial burden to the family. This study was done to assess the knowledge and awareness of parents having a thalassemic child and to ameliorate their experiences in the upbringing of their child.Methods:A cross sectional, descriptive study was conducted in Pediatric Ward of a Tertiary care Hospital in Navi Mumbai from May-August 2016 in which parents of 40 beta Thalassemia major children between age group of 6 months to 15 years were enrolled. Parents were interviewed through a questionnaire to assess their knowledge, awareness, the practices they follow in regard to the transfusion, treatment, vaccination and prevention of thalassemia. The study also focuses on the emotional suffering of the parents.Results: 47.5% of parents were aware of thalassemia being a genetic disorder.62.5% were aware of regular blood transfusion. 23 parents were aware of the regular medications taken by their children. 42.5% parents had adequate knowledge of the optional vaccines to be taken. 90% parents followed a good practice of getting their child for regular blood transfusion and 92.5% gave them regular medicines.31 parents would periodically get their child investigated but 65% of parents lacked in giving optional vaccines to the child.60% agreed to undergo MTP while only 45% knew about the antenatal detection.Conclusions:Majority of parents followed good practice and had a positive attitude, though the knowledge and awareness about the disease was inadequate. 

A Consumer’s Guide to Eggs

EDIS ◽  
2013 ◽  
Vol 2013 (11) ◽  
Author(s):  
Jeanine Beatty ◽  
Karla Shelnutt ◽  
Gail P. A. Kauwell
Keyword(s):  
United States ◽  
Fatty Acid ◽  
New World ◽  
The United States ◽  
Omega 3 ◽  
Bottom Line ◽  
Christopher Columbus ◽  
Food Stores ◽  
Omega 3 Fatty Acid ◽  
Chicken Eggs

People have been eating eggs for centuries. Records as far back as 1400 BC show that the Chinese and Egyptians raised birds for their eggs. The first domesticated birds to reach the Americas arrived in 1493 on Christopher Columbus' second voyage to the New World. Most food stores in the United States offer many varieties of chicken eggs to choose from — white, brown, organic, cage free, vegetarian, omega-3 fatty acid enriched, and more. The bottom line is that buying eggs is not as simple as it used to be because more choices exist today. This 4-page fact sheet will help you understand the choices you have as a consumer, so you can determine which variety of egg suits you and your family best. Written by Jeanine Beatty, Karla Shelnutt, and Gail Kauwell, and published by the UF Department of Family Youth and Community Sciences, November 2013. http://edis.ifas.ufl.edu/fy1357

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