scholarly journals A study on reliable diagnosis of allergic respiratory diseases by using eosinophil count in nasal and blood smear: a prospective study in tertiary care centre

2019 ◽  
Vol 6 (2) ◽  
pp. 343
Author(s):  
Korisipati Ankireddy ◽  
Mallikarjuna M.
Keyword(s):  
Allergic Rhinitis ◽  
Risk Factor ◽  
Bronchial Asthma ◽  
Eosinophil Count ◽  
Tertiary Care ◽  
Geographical Area ◽  
Care Centre ◽  
Common Risk Factor ◽  
Peripheral Smear ◽  
Reliable Diagnosis

Background: Allergic rhinitis and asthma are two very common allergic diseases of respiratory tract in pediatric patients. In this geographical area, where the prevalence of allergens exists, the role of allergens as the etiological factor is higher in allergic respiratory disorders. Confirmation of allergen as etiologic agent is cumbersome in a small setup, where IgE estimation and allergy tests are not accessible. In this study, the simple test of peripheral smear and nasal smear eosinophil count as a reliable diagnosis to solve the above problem and establishing allergy as etiological agent has been tried.Methods: A present study which was conducted over 2 years in children between 2 to 12 years who visited tertiary health care centre, Kurnool medical college and general hospital. The allergic respiratory cases based on typical history and clinical features were included in the study and investigated for nasal and blood eosinophilia. Children with TB, recurrent and chronic pneumonia, malnutrition, malignancy, collagen vascular disorders and those who are on steroid therapy were excluded from the study. The clinical profile of allergic rhinitis with or without asthma and nasal and blood eosinophils are studied.Results: Out of 120 patients, there was male predominance and incidence was increasing as age increases. Dust is the most common risk factor for allergic rhinitis followed by weather changes, whereas in allergic rhinitis with bronchial asthma, weather change is common risk factor followed by dust and family history.Conclusions: In children with allergic rhinitis with or without bronchial asthma, there is positive relation between nasal and peripheral smear eosinophil count.

scholarly journals Study of Eosinophil Count in Nasal and Blood Smear in Allergic Respiratory Diseases

2016 ◽  
Vol 3 (1) ◽  
pp. 44 ◽  
Author(s):  
Ravindra Sonawane ◽  
Nilesh Ahire ◽  
Suhas Patil ◽  
Abhijit Korde
Keyword(s):  
Allergic Rhinitis ◽  
Risk Factor ◽  
Bronchial Asthma ◽  
Eosinophil Count ◽  
Respiratory Diseases ◽  
Geographical Area ◽  
Common Risk Factor ◽  
Peripheral Smear ◽  
Health Care Center ◽  
Male Predominance

<strong>Introduction:</strong> Allergic rhinitis and asthma are two very common allergic diseases of respiratory tract in pediatric patients. In this geographical area, where the prevalence of allergens exists, the role of allergens as the etiological factor is higher in allergic respiratory disorders. Confirmation of allergen as etiologic agent is cumbersome in a small setup, where IgE estimation and allergy tests are not accessible. In this study, the simple test of peripheral smear and nasal smear eosinophil count as a reliable diagnosis to solve the above problem and establishing allergy as etiological agent has been tried. <strong>Material and Methods:</strong> For the present study which was conducted over 2 years in children between 2 to 12 years who visited tertiary health care center, Nashik. The allergic respiratory cases based on typical history and clinical features were included in the study and investigated for nasal and blood eosinophilia. Children with TB, recurrent and chronic pneumonia, malnutrition, malignancy, collagen vascular disorders and those who are on steroid therapy were excluded from the study. The clinical profile of allergic rhinitis with or without asthma and nasal and blood eosinophils are studied. <strong>Result:</strong> Out of 100 patients, there was male predominance and incidence was increasing as age increases. Dust is the most common risk factor for allergic rhinitis followed by weather changes, whereas in allergic rhinitis with bronchial asthma, weather change is common risk factor followed by dust and family history. In children with allergic rhinitis with or without bronchial asthma, there is positive relation between nasal and peripheral smear eosinophil count. <strong>Conclusion:</strong> So, nasal eosinophil count which is simple, non-invasive, economical and reliable can be used as an alternative to invasive peripheral smear eosinophil count as both are equally efficacious in diagnosing allergic respiratory diseases.

scholarly journals Effectiveness of leukotriene receptor antagonists in the treatment for atopic pathology in children

2020 ◽  
pp. 38-42
Author(s):  
A. I. Zariankina ◽  
M. Kh. Mirrakhimova ◽  
E. R. Shamsieva
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Bronchial Asthma ◽  
Eosinophil Count ◽  
Allergic Diseases ◽  
Receptor Antagonists ◽  
Leukotriene Receptor Antagonists ◽  
Leukotriene Receptor

Objective: to study the effectiveness of leukotriene receptor antagonists in the treatment foratopic pathology in children.Material and methods. 224 children with allergic diseases were prescribed to take montelucast for 3– 6 months.Results. Taking montelucast has lead to positive clinical dynamics in 75 % of the cases.A significant reduction of the eosinophil count was achieved on days 10–15 of the therapy. The Cys-LTC4/D4/E4 indices came to normal after a one-month course of montelucast therapy in 40.3 % of cases in children with bronchial asthma, in 63.3 % of cases in children with allergic rhinitis and in 60.5 % of cases in children with atopic dermatitis.Conclusions. The use of montelucast has significantly enhanced the control incidencerate ofallergic diseases in children.

scholarly journals A PROSPECTIVE STUDY ON CLINICAL PROFILE OF STROKE PATIENTS ATTENDING IN A TERTIARY CARE HOSPITAL OF GUWAHATI, ASSAM.

2020 ◽  
pp. 1-4
Author(s):  
Dhrubajyoti Choudhury* ◽  
N. C. Borah ◽  
P. S. Deb ◽  
Amit Ranjan Baruah ◽  
Kinzang Wangda ◽  
...  
Keyword(s):  
Risk Factor ◽  
Prospective Study ◽  
Cerebrovascular Disease ◽  
Tertiary Care ◽  
Common Type ◽  
Care Hospital ◽  
Medical Sciences ◽  
Stroke Patients ◽  
Common Risk Factor ◽  
A Prospective Study

Cerebrovascular disease include most common devastating disorders :ischaemic stroke and haemorrhagic stroke.The incidence of cerebrovascular disease increases with age and the number of strokes is projected to increase as the elderly population grows.A stroke is the second leading cause of death worldwide. Some of the Indian studies have shown a stroke prevalence of 471.58/100000 population. OBJECTIVE:To study the clinical presentation, risk factors,neurological presentation,pattern of brain strokes,areas of brain affected as per CT/MRI Brain scan findings in a newly admitted patients in GNRC Institute of Medical Sciences, North Guwahati,Assam. METHODS:This is a prospective study included all new patients with stroke admitted in ICU and Ward under Neurology Department of GNRC institute of Medical Sciences ,North Guwahati,Assam,from 1st August,2018 to 31st July ,2019. RESULTS: The cerebrovascular strokes are more common in males (64.4%) than females (35.6%). Most common age group was 58-67 years (28.29%).Most common clinical feature was hemiplegia (71.21%).Most common risk factor was Hypertension (89.51%) followed by diabetes mellitus(51.70%) . Most common type of stroke was haemorrhagic (60.24%) followed by ischaemic (39.75%). In stroke infarct most common involved areas were parietal (13.65%). In hemorrhagic stroke most common site was basal ganglia (21.95%) followed by thalamus (10.97%). CONCLUSION: Males were more commonly affected with cerebrovascular accident with hypertension was the most common risk factor among the stroke patients and most common type of stroke was haemorrhagic.

scholarly journals Risk factors for ventricular tachycardia in acute ST-elevated myocardial infarction patients of a tertiary care hospital of Peshawar

2021 ◽  
Vol 6 (4) ◽  
pp. 12-15
Author(s):  
Inam Ullah ◽  
Ashfaq Ahmad Shah Bukhari ◽  
Mehwish Durrani ◽  
Zulfania Khan ◽  
Saman Tauqir ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Risk Factor ◽  
Ventricular Tachycardia ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Anterior Wall ◽  
Care Hospital ◽  
Common Risk Factor ◽  
Common Location

Introduction: Ventricular arrhythmias are the most common cause of death in various ST-Elevated Myocardial Infarction (STEMI) patients and can be prevented if diagnosed and managed in time. Objectives: To document the occurrence of ventricular tachycardia in patients with acute ST-segment elevated myocardial infarction (STEMI) admitted to a tertiary care hospital of Peshawar and to identify associated risk factors. Materials & Methods: A descriptive cross-sectional study consisting of 252 MI patients of 51-60 years of age, were observed for the presence of ventricular tachycardia at Lady Reading Hospital, Peshawar from September 2017 to January 2018. Results: Hypertension was found to be the most common risk factor for ventricular tachycardia observed in 180 patients. Diabetes mellitus was the 2nd most common risk factor present in 104 patients while smoking was found in 56 patients. The most common location of ST-Elevation MI was anterior wall myocardial infarction (30.2%) occurring in 76 patients. Conclusion: Ventricular tachycardia occurred in a quarter of the patients presenting with acute ST-elevated myocardial infarction, and was more common in anterior wall MI followed by extensive anterior wall MI.  

scholarly journals Serum immunoglobulin E and absolute eosinophil count as markers of severity in childhood asthma

2020 ◽  
Vol 7 (2) ◽  
pp. 413
Author(s):  
Pinakin P. Trivedi ◽  
Ami H. Patel
Keyword(s):  
Bronchial Asthma ◽  
Eosinophil Count ◽  
Immunoglobulin E ◽  
Tertiary Care ◽  
Persistent Asthma ◽  
Care Hospital ◽  
Total Ige ◽  
Absolute Eosinophil Count ◽  
Chronic Inflammatory Condition ◽  
Serum Total Ige

Background: Asthma is a chronic inflammatory condition of the airways resulting in increased airway reactivity to a variety of stimuli like allergens, irritants, viruses and exercise. There is a strong association between the exposure of allergens and development of asthmatic symptoms. A hypersensitivity reaction initiated by immunologic mechanisms mediated by Immunoglobulin E (IgE) antibodies occurs in allergic asthma. IgE and eosinophils play an important role in the inflammatory process resulting in bronchial hyperresponsiveness. The aim of this study was to evaluate serum total IgE levels and Absolute Eosinophil Count (AEC) as markers of disease activity and study their association with the severity of bronchial asthma in children.Methods: A prospective study was conducted in the paediatric department of a tertiary care hospital in Ahmedabad, Gujarat, India from July 2017 to December 2018. Children between 4-14 years of age diagnosed as having bronchial asthma were included in the study. Serum total IgE levels and absolute eosinophil count were done in all the study participants and their correlation with the severity of asthma was assessed.Results: Of the total 109 patients of asthma, 44(40.4%) had intermittent asthma, 30(27.5%) mild persistent, 25(22.9%) moderate persistent and 10(9.2%) severe persistent asthma. Serum total IgE levels were raised above the normal limits for age in 94(86.2%) patients and increased AEC was found in 61(56 %) patients. Both serum total IgE levels and AEC increased significantly (p<0.0001) with increasing severity of asthma.Conclusions: Serum total IgE levels and AEC can be used to predict the severity of asthma in children.

scholarly journals Risk Factors Associated With Sino-Nasal Polyposis And Its Relationship With The Occupational Inhalants

2019 ◽  
Vol 09 (04) ◽  
pp. 290-293
Author(s):  
Qaisar Sajad ◽  
Ayub Musani ◽  
Faheem Ahmed Khan
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Nasal Polyposis ◽  
Local Population ◽  
Tertiary Care ◽  
Nasal Allergy ◽  
Care Hospital ◽  
Common Risk Factor ◽  
Factors Associated ◽  
Number Of Patients

Objective: To determine the risk factors associated with sino-nasal polyposis and its relationship with the exposure of occupational inhalants in patients presenting in a tertiary care hospital of Karachi. Study design and Settings: Cross-sectional study conducted at department of otorhino-laryngology Karachi Medical & Dental College and Abbasi Shaheed Hospital Karachi for a period of two and a half years from October 2015 to April 2018. Methodology: Total number of patients included for this study were 221 patients with diagnosis of bilateral and multiple nasal polyposis with age greater than 10 years. Specifically, designed proforma was used for data collection specially in relation with occupation and exposure to different occupational inhalants and entered in SPSS version 23 for analysis. Results: There were 133 male and 88 female patient with a mean age was 36.16 ± 12.33 years. Mostly patients belonged to poor socio-economic status i.e. 133 (60.70%). Allergic rhinitis or nasal allergy was the most common risk factor present in 114 patients (51.6%) while aspirin hypersensitivity was the least common risk factor present in only 19 patients (8.5%). Most of the patients (76 or 34.4%) were related with one or the other form of agriculture and were exposed to different occupational inhalants like mud, pollens, animals and plants. Conclusions: Nasal allergy is the most common risk factor and occupational inhalant specially related with agriculture, poultry and pets are the common agents responsible for nasal polyposis in our local population.

scholarly journals CLINICAL AND DEMOGRAPHIC PROFILE OF PATIENTS DIAGNOSED AS BRONCHIAL ASTHMA IN A TERTIARY CARE CENTRE

2019 ◽  
Vol 6 (35) ◽  
pp. 2382-2386
Author(s):  
Ramakrishna R. ◽  
Haribabu R. ◽  
Hari Priya S. ◽  
Tejaswi J. ◽  
Sd. Mehatab Banu ◽  
...  
Keyword(s):  
Bronchial Asthma ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Demographic Profile
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