scholarly journals Oromucosal lesions in women smokers: an Indian perspective

2021 ◽  
Vol 8 (5) ◽  
pp. 2619
Author(s):  
Vaishali Waghmare Shende ◽  
Shruti Kaushik ◽  
Indu Nagpal
Keyword(s):  
Side Effects ◽  
Young Woman ◽  
College Campuses ◽  
Indian Society ◽  
Substantial Body ◽  
Women Smokers ◽  
Tobacco Addiction ◽  
Indian Perspective

Women smoking is looked down upon by Indian society. However, a young woman smoking is not a rare sight on college campuses in metro cities. Substantial body of literature indicates that nicotine is the major component which leads to addiction. The habit which starts to look cool and fashionable in no time becomes an addiction. Indian society, which doesn’t acknowledge that women are indulging in smoking, makes the whole fight about tobacco addiction a turbulent journey. As society doesn’t accept that women smoke, there is no need to create awareness about its gendered impact. The study was undertaken by evaluating the oromucosal conditions and haemoglobin levels of 100 women smokers. Smokers’ palate, smoking associated pigmentation on lips and calculus deposits were observed in most of the participants. The participants were not aware about the hormonal issues and detrimental side effects of smoking to their health.

scholarly journals Cannabis hyperemesis syndrome

2018 ◽  
pp. bcr-2018-226524 ◽  
Author(s):  
Umesh Sharma
Keyword(s):  
Abdominal Pain ◽  
Side Effects ◽  
Young Woman ◽  
Cannabis Use ◽  
Laboratory Examination ◽  
History Of ◽  
Topical Capsaicin ◽  
Cannabis Hyperemesis Syndrome

A young woman with chronic cannabis use presents with 2-day history of cyclical nausea, vomiting and abdominal pain. Clinical and laboratory examination excluded other causes. Patient’s symptoms improved with topical capsaicin, hot showers, antiemetics and she was subsequently discharged home 4 days later. The patient was educated on side effects of cannabis use and chose to stop cannabis use completely.

scholarly journals Problems related to intellectual property and children's education

2018 ◽  
Vol 6 (9) ◽  
pp. 332-339
Author(s):  
Ompal Singh ◽  
Hamendra Singh
Keyword(s):  
Intellectual Property ◽  
Human Life ◽  
Indian Society ◽  
Children's Education ◽  
Wide Range ◽  
Children’S Education ◽  
Indian Perspective

Education is the cornerstone of human life. Only through education can a person be able to achieve a specific personality. Sometimes illiterate person is also effective; However, due to lack of education, he is mainly attached to his environment, due to which he is often unable to give wide range of his specialties so that he can benefit the entire Indian and foreign citizens. The current global scenario indicates that a country whose citizens are deprived of education cannot sustain on the global plane. In the Indian perspective, many problems related to children's education are becoming visible, due to which every section of Indian society is not developing equally. Even after many government schemes, the problems related to children's education remain the same and Indian intellectual property is declining. शिक्षा मानव जीवन का श्रंृगार है । शिक्षा के माध्यम से ही व्यक्ति एक विशिष्ट व्यक्तित्व को प्राप्त करने में सक्षम हो सकता है । अनेक बार अशिक्षित व्यक्ति भी प्रभावशील होता है; परन्तु, शिक्षा के अभाव में वह मुख्य रूप से अपने परिवेश से ही अधिकतम जुड़ा हुआ रहता है जिस के कारण वह अपनी उन विशिष्टताओं को व्यापक रूप प्रदान करने में प्रायः अक्षम रहता है जिन से कि वह सम्पूर्ण भारतीय और विदेशी नागरिकों को लाभ पहुँचा सके । वर्तमान वैश्विक परिदृश्य यह संकेत करता है कि वह देश वैश्विक धरातल पर टिका नहीं रह सकता जिस के नागरिक शिक्षा से वंचित हैं । भारतीय परिप्रेक्ष्य में बच्चों की शिक्षा से सम्बन्धित अनेक समस्याएँ दृष्टिगोचर हो रही हैं, जिस के कारण भारतीय समाज का प्रत्येक वर्ग समान रूप से विकसित नहीं हो रहा है । अनेक शासकीय योजनाओं के पश्चात भी बच्चों की शिक्षा से सम्बन्धित समस्याएँ पूर्ववत ही हैं और भारतीय बौद्धिक सम्पदा में कमी हो रही है ।

scholarly journals How reliable are ligand-centric methods for Target Fishing?

2015 ◽  
Author(s):  
Antonio Peón ◽  
Cuong C. Dang ◽  
Pedro J. Ballester
Keyword(s):  
Side Effects ◽  
Computational Methods ◽  
Small Molecule ◽  
Target Prediction ◽  
Predictive Performance ◽  
Control Group ◽  
Substantial Body ◽  
Small Molecule Drugs ◽  
Approved Drugs ◽  
Target Fishing

Computational methods for Target Fishing (TF), also known as Target Prediction or Polypharmacology Prediction, can be used to discover new targets in small-molecule drugs. This may result in repositioning the drug in a new indication or improving our current understanding of its efficacy and side effects. While there is a substantial body of research on TF methods, there is still a need to improve their validation, which is often limited to a small part of the available targets and not easily interpretable by the user. Here we discuss how target-centric TF methods are inherently limited by the number of targets that can possibly predict (this number is by construction much larger in ligand-centric techniques). We also propose a new benchmark to validate TF methods, which is particularly suited to analyse how predictive performance varies with the query molecule. On average over approved drugs, we estimate that only five predicted targets will have to be tested to find two true targets with submicromolar potency (a strong variability in performance is however observed). In addition, we find that an approved drug has currently an average of eight known targets, which reinforces the notion that polypharmacology is a common and strong event. Furthermore, with the assistance of a control group of randomly-selected molecules, we show that the targets of approved drugs are generally harder to predict.

Internet Overuse on College Campuses

2011 ◽  
pp. 146-163 ◽  
Author(s):  
Mary Jane Miller
Keyword(s):  
Higher Education ◽  
Side Effects ◽  
Internet Addiction ◽  
Side Effect ◽  
Internet Use ◽  
Colleges And Universities ◽  
College Campuses ◽  
Technological Revolution ◽  
Rip Van Winkle ◽  
University Of Guam

The changes wrought in the last 10 years alone are sufficiently awesome to astound and confuse any Rip Van Winkle who may have managed to sleep through the decade. As with all man-made marvels, however, along with the much touted fabulous benefits and glittering accomplishments, it seems there always exist undesirable side effects. One side effect of the technological revolution with the potential to cause harm is an inclination by some people, most notably students in higher education, for excessive and compulsive Internet use. Often called Internet addiction, this disorder is particularly prevalent on the campuses of colleges and universities, and for some students, it has the potential to be as destructive as excessive use of alcohol, tobacco or drugs. This chapter talks about Internet overuse on college campuses in general and discusses a survey of 305 University of Guam students regarding their Internet use.

scholarly journals Clozapine-induced severe eosinophilia: report of a case with good outcome

2013 ◽  
Vol 62 (3) ◽  
pp. 240-243 ◽  
Author(s):  
Carla R. B. Marcelino ◽  
Clarissa de R. Dantas
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Literature Review ◽  
Young Woman ◽  
Psychotic Symptoms ◽  
Good Outcome

INTRODUCTION: Clozapine is the antipsychotic of choice in the treatment of refractory schizophrenia. However, its side effects, such as eosinophilia, may preclude its use. METHODS: Case report and literature review. RESULTS: Young woman, 19 years old, diagnosed with hebefrenic schizophrenia, admitted at Unicamp's psychiatry ward after psychotic symptoms relapse. Clozapine was started after unsuccessful attempts with risperidon and olanzapine. By the fourth week of clozapine use, eosinophils began to increase. Drug titration was stopped, but eosinophils counts continued to rise up, reaching the mark of 5200/mm³. Due to severity of psychotic symptoms and to the good response obtained with clozapine, we decided to investigate organs involvement before withdrawing the medication. As the patient had no organs involvement, clozapine was maintained and one month after eosinophils peak, it was already normalized. CONCLUSION: Eosinophilia should not necessarily lead to clozapine's withdrawal. Patients who present eosinophilia must be at rigorous observation for organs involvement, and if there is no such involvement, clozapine might be maintained, considering the possible benign and transitory nature of the eosinophils count elevation.

Reversible Reduction in Renal Function During Treatment with Captopril

PEDIATRICS ◽  
1983 ◽  
Vol 71 (5) ◽  
pp. 839-840
Author(s):  
RICHARD D. COLAVITA ◽  
KAREN M. GAUDIO ◽  
NORMAN J. SIEGEL
Keyword(s):  
Renal Failure ◽  
Renal Function ◽  
Side Effects ◽  
Renal Artery ◽  
Renal Artery Stenosis ◽  
Young Woman ◽  
Pediatric Patient ◽  
Side Effect ◽  
Severe Hypertension ◽  
Reversible Reduction

Captopril is known to be effective for the control of hypertension in adults.1,2 Several recent reports have described the efficacy of this drug in children3,4 and neonates.5 Side effects include neutropenia, proteinuria, rashes, ageusia, hypotension, and hyperkalemia. Farrow and Wilkinson6 described a case of reversible renal failure during therapy with captopril in a young woman with severe hypertension secondary to renal artery stenosis. However, renal failure is not a well-appreciated side effect of this drug and has not been described previously in a pediatric patient during treatment with captopril. We report two cases in which a reversible decline in renal function occurred in children being treated with captopril.

scholarly journals A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Junko Takata ◽  
Simon M. Durkin ◽  
Solomon Wong ◽  
Michael S. Zandi ◽  
Josephine K. Swanton ◽  
...  
Keyword(s):  
Case Report ◽  
Side Effects ◽  
Young Woman ◽  
Neuropsychiatric Symptoms ◽  
Causal Link ◽  
Difficult Case ◽  
Extensive Investigation ◽  
Case Presentation ◽  
Neuropsychiatric Side Effects

Abstract Background Vaccination against COVID-19 continues apace, but side-effects, both common and severe, continue to be reported. We report here the first published case of COVID-19 vaccine-related encephalitis. Case presentation A young woman presented with acute neuropsychiatric symptoms following recent ChAdOx1 nCoV-19 vaccination. Extensive investigation did not identify alternative causes. Conclusions This difficult case is here described, including presentation, investigation, and management. Further study on neuropsychiatric side-effects of COVID-19 vaccination, including investigation as to whether there may be a causal link, is required.

Stellar Evolution

1962 ◽  
Vol 11 (02) ◽  
pp. 137-143
Author(s):  
M. Schwarzschild
Keyword(s):  
Solar System ◽  
Stellar Evolution ◽  
Space Craft ◽  
New Techniques ◽  
Substantial Body ◽  
Individual Stars ◽  
The Past ◽  
Evolution Of Galaxies ◽  
History Of ◽  
Fast Flow

It is perhaps one of the most important characteristics of the past decade in astronomy that the evolution of some major classes of astronomical objects has become accessible to detailed research. The theory of the evolution of individual stars has developed into a substantial body of quantitative investigations. The evolution of galaxies, particularly of our own, has clearly become a subject for serious research. Even the history of the solar system, this close-by intriguing puzzle, may soon make the transition from being a subject of speculation to being a subject of detailed study in view of the fast flow of new data obtained with new techniques, including space-craft.

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