scholarly journals A study of head and neck space infections and their sensitivity pattern at tertiary care hospital

Author(s):  
Simmi Jindal ◽  
Suchina Parmar ◽  
Jailal Davessar ◽  
A. G. S. Bawa ◽  
Gurbax Singh ◽  
...  

<p class="abstract"><strong>Background:</strong> Head and neck space infections including submandibular, buccal, diffuse neck space, peritonsillar, parapharyngeal, parotid, submental, retropharyngeal, result in frequent hospital visits. Infection can be mild or severe life threatening infection.</p><p class="abstract"><strong>Methods:</strong> 40 patients with head and neck space infections were considered. Pus samples were collected with aseptic precautions and sent to department of microbiology for culture and antibiotic sensitivity.  </p><p class="abstract"><strong>Results:</strong> The most common head and neck space infections are submandibular followed by buccal, diffuse neck abscess, peritonsillar, parapharyngeal, parotid, submental and retropharyngeal. Incidence of aerobic growth is 60%, fungal 10%, anaerobic 7.5%, tubercular 7.5% and no growth 15%. Predominant aerobes are <em>Staphylococcus aureus</em>, <em>Pseudomonas aeruginosa</em>, Methicillin Resistant<em> Staphlococcus aureus</em>, <em>Klebsiella</em> species and anaerobes are Peptostreptococcus and bacteroides and fungal species is <em>Candida</em>. Aerobic organism showed maximum sensitivity to Amikacin, Vancomycin, Linezolid, Piperacillin+Tazobactum, Clindamycin, Erythromycin, Cefoperazone, Ceftriaxone and maximum resistant to Levofloxacin, Cefoperazone, Ceftriaxone, Meropenem. Anaerobic bacteria showed sensitivity to Clindamycin, Metronidazole and Colistin and resistance to Vancomycin.</p><p class="abstract"><strong>Conclusions:</strong> Bacteriological examination and culture of head and neck abscesses helps to identify causative organisms. It helps to isolate even rarest of organisms and by knowing their sensitivity pattern we can detect specific therapy against them. Thus it helps in more effective treatment and fast recovery.</p>

Author(s):  
Kirti Hemwani ◽  
P. S. Nirwan ◽  
Preeti Shrivastava ◽  
Abhiraj Ramchandani

Background: Nonfermentative gram negative bacilli (NFGNB) frequently considered as commensals or contaminants but the pathogenic potential of nonfermenters has been proved beyond doubt. They are resistant to commonly used antimicrobials. Aim: This study was undertaken to identify the nonfermenters isolated from various clinical samples and to know their Antibiotic sensitivity pattern. Materials and Methods: The present study was carried out on 150 strains of Nonfermenters isolated from 1200 various non repetitive clinical samples received in Department of Microbiology, NIMS Jaipur. Nonfermenters were identified using a standard protocol and their antibiotic susceptibility testing was performed with the help of the modified Bauer disc diffusion method. Results: Out of 150 nonfermenters isolated, Pseudomonas aeruginosa was the most common isolate 134 (89.33%) followed by Acinetobacter baumannii 16 (10.67%). Among all clinical samples Pus and Wound Discharge yield maximum isolates of NFGNB i.e. 54 (36%) % followed by sputum (39.0%). Most sensitive drug against NFGNB was Polymyxin-B (100%) followed by Imipenem (86 %) and Amikacin (71.33 %). Conclusion: Nonfermenters have a great potential to survive in a hospital environment so implementation of antibiotic stewardship programs and strict infection control practices will be required to prevent or slow down their emergence and spread. Keywords:  Nonfermenters,  Polymyxin-B, Pseudomonas, Acinetobacter.


Author(s):  
Vijayashree V. ◽  
Saikeerthana D. ◽  
Prabha P.

Background: The genus Klebsiella of Enterobacteriaceae family is ubiquitous in nature. They cause many nosocomial infections like pneumonia, urinary tract infections, wound infections, bacteremia and septicemia. Multidrug resistance is seen in Klebsiella which serves as the most common cause of increased morbidity and mortality. This study reveals the prevalence and antibiotic sensitivity pattern of Klebsiella species from various clinical samples. The primary objectives are as follows: To isolate and characterize Klebsiella species from various clinical samples. To study the antibiotic susceptibility pattern of Klebsiella isolates.Methods: This prospective study was conducted in our tertiary care hospital during the period from August 2019 to October 2019. A total of 3521 samples were tested during this period. The samples include blood, sputum, urine, and pus.Results: Out of the total samples tested,1106 samples were showing the growth of the organisms. Among this,351 were identified as Klebsiella species and the highest rate of isolation of Klebsiella species is from the sputum sample and also the same was reported high in medical wards. The study also shows that the isolation of Klebsiella species shows male preponderance when compared to females. The antibiotic sensitivity pattern was done by Kirby-Bauer's disc diffusion method and the sensitivity was noted to be higher to amikacin and ciprofloxacin.Conclusions: Thus, this study shows the prevalence rate of Klebsiella species and sensitivity pattern of Klebsiella, which may help select appropriate antibiotics and prevent overuse and misuse of antibiotics.


2015 ◽  
Vol 1 (1) ◽  
pp. 3-7
Author(s):  
Fatema Nusrat ◽  
K.M. Shahidul Islam ◽  
S.M. Shamsuzzaman ◽  
Md. Abdullah Yusuf ◽  
Aleya Farzana ◽  
...  

Background: Antibiotic sensitivity pattern of Neisseria gonorrhoae is changing frequently. Objective: The purpose of the present study was to see the antibiotic sensitivity pattern of Neisseria gonorrhoae isolated from women presented with cervicitis.Methodology: This cross sectional study.carried out in the Department  of Microbiology at Dhaka Medical College, Dhaka from July 2011 to December 2012 for a period of one and half year. All the women presented with or without the clinical features of  cervicitis at child bearing age (15 to 49 yrs) with or without pregnancy were enrolled as study population. Endocervical swabs were collected  for Gram staining, culture, biochemical test from clinically diagnosed  patients of cervicitis for presumptive identification of Neisseria gonorrhoeae. The isolates with presumptive identification were confirmed by rapid carbohydrate utilization test (RCUT), which differentiates  N.gonorrhoeae from other Neisseria. Antimicrobial susceptibility test was done according CLSI guideline. Result: A total 245 females were recruited of which N. gonorrhoeae were detected from 39(15.9%) cases. Among 39 positive cases of gonococcal cervicitis, 19 (48.71%) were detected in the age group of 21-30 years. 56.41% were sensitive and 30.76% were resistant to ceftriaxone. Similarly 51.28% were sensitive and 23.07% were resistant to cefuroxime; 23.07% sensitive, 30.76% moderately sensitive and 46.15% resistant to ciprofloxacin. Conclusion: Gonococcal cervicitis is found in a high frequency rate with a reduced sensitivity to antibiotics especially ciprofloxacin, second and third generation cephalosporins.Bangladesh J Infect Dis 2014;1(1):3-7


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