scholarly journals Comparative study of biofilm formation in tubotympanic and atticoantral ear disease

2021 ◽  
Author(s):  
Sanjay Kumar Saroj ◽  
Rajesh Kumar ◽  
Sushil Kumar Aggarwal ◽  
Tuhina Banerjee ◽  
Ashvanee Kumar Chaudhary ◽  
...  
Keyword(s):  
Otitis Media ◽  
Biofilm Formation ◽  
Tertiary Care ◽  
Chronic Otitis Media ◽  
Uttar Pradesh ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Cross Sectional ◽  
Suppurative Otitis Media ◽  
Common Organism

<p class="abstract"><strong>Background:</strong> Biofilm is an organized bacterial community that may be homogeneous or heterogeneous. It plays a significant role in the pathogenesis of chronic rhinosinusitis, chronic tonsillitis and chronic suppurative otitis media. Biofilms may explain the recurrence and recalcitrant episodes of otorrhea in chronic otitis media (COM). The objective of this study was to detect biofilm formation in chronic suppurative otitis media and compare the pattern of biofilm formation in tubotympanic and atticoantral ear diseases.</p><p class="abstract"><strong>Methods:</strong> This was a prospective cross sectional study at a tertiary care hospital in Varanasi, Uttar Pradesh, India. Patients included in the study ranged from 10 to 65 years of age from  both the sexes and varying socioeconomic status. Samples were collected using sterile precautions in cases of tubotympanic as well as atticoantral COM. The collected samples were directly inoculated onto MacConkey and blood agar media. LisaScan® EM microtitter plate reader was used to identify the presence of biofilm.</p><p class="abstract"><strong>Results:</strong> The most common organism was <em>P. aeruginosa</em> and <em>S. aureus</em> followed by <em>Moraxella catarrhalis</em> whereas in cases with tubotympanic COM, most common organism was <em>S. aureus</em>. We found that, in atticoantral type of COM biofilm formation was significantly more common as compared to that in tubotympanic type of COM.</p><p class="abstract"><strong>Conclusions:</strong> Biofilm formation in COM is even higher when atticoantral disease is present.</p>

scholarly journals Bacterial Profile and Antimicrobial Susceptibility Pattern of Chronic Suppurative Otitis Media from a Tertiary Care Hospital in Kannauj, Uttar Pradesh, India

2021 ◽  
Author(s):  
Kiran Yadav ◽  
Sandeep Kaushik ◽  
Kumkum Rani ◽  
Anuj Kumar Tyagi
Keyword(s):  
Otitis Media ◽  
Antimicrobial Susceptibility ◽  
Tertiary Care ◽  
Uttar Pradesh ◽  
Tympanic Membrane Perforation ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Susceptibility Pattern ◽  
Suppurative Otitis Media ◽  
Antimicrobial Susceptibility Pattern

Introduction: Chronic Suppurative Otitis Media (CSOM) is a chronic and persistent inflammation of the mucosal lining of middle ear cleft which presents with recurrent ear discharge through a tympanic membrane perforation. CSOM is a worldwide disease and has higher prevalence in developing countries causing serious local damage and threatening complications. Aim: To determine the profile of CSOM, its causative agents and their antibiotic susceptibility pattern. Materials and Methods: The present study was a retrospective study in which data for culture and antimicrobial susceptibility profile of CSOM cases was retrieved from Microbiology department of Government Medical College, Kannauj, Uttar Pradesh, India, from January 2019 to October 2019 the analysis of data was done in February 2020. Two hundred pus swabs from discharging ears were processed during the study period for aerobic bacterial culture and antimicrobial susceptibility pattern in Microbiology department using standard microbiological techniques. The result analysis of the study was expressed as percentage and proportion for distribution of CSOM cases. Results: Out of 200 patients, 114 (57%) were males and 86 (43%) females. Among the 200 cases, 147 (73.5%) cases showed growth and 53 (26.5%) showed no growth. The most common organism isolated in this study was Pseudomonas aeruginosa, 67 (42.40%) followed by Staphylococcus aureus.48 (30.37%) and Klebsiella spp. 23 (14.55%). Gentamicin (85%) and amikacin (83%) had high level of antibacterial activity on all the isolates. Meropenem was found to be most effective drug for gram negative isolates. All Staphylococcus spp isolates were sensitive to vancomycin (100%). Conclusion:Pseudomonas aeruginosa was the most predominant organism isolated in otitis media patients. Most of the isolates were sensitive to meropenem.

scholarly journals An association of sensorineural hearing loss in mucosal type of chronic suppurative otitis media

2018 ◽  
Vol 4 (3) ◽  
pp. 712
Author(s):  
Santosh Malashetti ◽  
Prabhu Khavasi ◽  
Prasen Reddy ◽  
Karra Bhargavi
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Otitis Media ◽  
Tertiary Care ◽  
Bone Conduction ◽  
Chronic Otitis Media ◽  
Sensorineural Hearing ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Suppurative Otitis Media

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media of mucosal variety is one of the most common cause of conductive hearing loss worldwide. Sensorinueral hearing loss is rare but well established complication of chronic suppurative otitis media of squamosal variety. We made an attempt to view the sensorineural hearing loss in mucosal type of chronic otitis media and keeping objectives and aims as follows occurrence of sensorinueral hearing loss in mucosal type of chronic suppurative otitis media; relation of sensorinueral component with age, gender and duration in mucosal type of chronic suppurative otitis media.</p><p class="abstract"><strong>Methods:</strong> A total of 105 cases of mucosal type of CSOM were studied retrospectively for the pattern of hearing impairement on the basis of pure tone audiogram in a Tertiary care hospital. Relation 0f sensorinueral hearing loss with with age, gender and duration in mucosal type of CSOM is compared and tabulated with various studies.  </p><p class="abstract"><strong>Results:</strong> Out of total 105 cases of CSOM of mucosal variety 30 (28.57%) had sensorinueral hearing loss affecting 13 males and 17 females with males to females ratio of 1:1.3.Mean bone conduction thresholds in males at 1 kh, 2 kh and 4 kh is 30.38%, 38.46% and 46.15% respectively and Mean bone conduction thresholds in females at 1 kh, 2 kh and 4 kh is 30.88%, 35% and 44.41% respectively.</p><p class="abstract"><strong>Conclusions:</strong> Significant sensorinueral hearing loss was seen in our study. Age, gender and duration didn’t have any impact on degree of sensorinueral hearing loss.</p>

scholarly journals “The Study of Bacteriological Agents of Chronic Suppurative Otitis Media Aerobic Culture and Antibiotic Sensitivity Testing Pattern at a Tertiary Care Hospital in and around Rajamundry: A cross-sectional study”

2021 ◽  
Vol 7 (4) ◽  
pp. 207-214
Author(s):  
Dr. Neelima Pantagada ◽  
◽  
Dr. Praveen Kavoori ◽  
Keyword(s):  
Otitis Media ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Sectional Study ◽  
Sensitivity Testing ◽  
Cross Sectional ◽  
Suppurative Otitis Media

Introduction: Chronic suppurative otitis media is a chronic infection of the middle ear and mastoidcavity which if not treated leads to partial or total loss of hearing and even life-threateningcomplications like meningitis and Intracranial abscess. Hence it is important to treat the persistentear discharge in CSOM according to the antimicrobial sensitivity of the organism isolated. Methods:This is a prospective cross-sectional study done in 135 clinically diagnosed patients of CSOM at GSLmedical college and General Hospital, Rajamundry, Andhra Pradesh from May 2019 to October 2019.Sterile swabs were used to collect pus from discharging ear and were inoculated onto Blood andMacConkey agar for 24-48 hrs, and identification of organisms was done by using standardbiochemical reactions and antibiotic sensitivity testing done by using modified Kirby- Bauer methodas per CLSI guidelines. Results: A total of 156 strains were isolated from 135 patients in thepresent study of which Pseudomonas aeruginosa and Staphylococcus aureus were amongst the mostisolated pathogens in culture. Imipenem showed the most sensitivity against Pseudomonas,subsequently levofloxacin and piperacillin. Linezolid was the most sensitive versus Staphylococcusensued by ciprofloxacin and cloxacillin. Conclusions: In the present study of Chronic suppurativeotitis media patients, Pseudomonas and Staphylococcus were highly prevalent and showed increasedresistance to beta-lactams and commonly used antimicrobial drugs. Antimicrobials like imipenem,piperacillin, and quinolones are effective against most cases of chronic suppurative otitis media

scholarly journals Association of hearing loss with depression, anxiety and stress in patients suffering from Chronic Suppurative Otitis Media

2019 ◽  
Vol 35 (2) ◽  
Author(s):  
Shafaque Mehboob Khan ◽  
Tariq Rafi ◽  
Naveed Ahmed ◽  
Mehjabeen Mehjabeen
Keyword(s):  
Hearing Loss ◽  
Otitis Media ◽  
Local Population ◽  
Tertiary Care ◽  
Pure Tone Audiometry ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Cross Sectional ◽  
Suppurative Otitis Media ◽  
Significant Difference

Objective: To study the correlation of hearing loss with depression, anxiety and stress in patients suffering from chronic suppurative otitis media in local population of Pakistan. Methods: This is a cross-sectional study conducted from May to September 2018 at tertiary care hospital of Karachi. One hundred and twenty patients of chronic suppurative otitis media were divided into three groups: Group-1 (maintained on ciprofloxacin), Group-2 (maintained on co-amoxicillin) and Group-3 (did not subject to the treatment).The measurement of hearing loss was carried out by pure tone audiometry (PTA) and the depression, anxiety and stress were scored taking depression, anxiety and stress scale (DASS) as tool. To observe the effect of hearing loss on different groups one way ANOVA was applied and Spearman correlation was used to find correlation of depression with hearing loss. Results: There was no significant difference found for hearing loss and severity among the groups treated with ciprofloxacin, co-amoxicillin and not maintained on antibiotic therapy. Positive correlations found between hearing loss and depression, anxiety and stress in patients of the three groups. Conclusion: Depression induced by hearing loss as a result of CSOM in patients need to be monitored during and after treatment and scored so that can be treated by counseling and antidepressant (if required). Information regarding this topic on population of Pakistan will be helpful for health care takers and policy makers to manage mental stress with hearing loss in CSOM. How to cite this:Mehboob S, Rafi SMT, Ahmed N, Mehjabeen. Association of hearing loss with depression, anxiety and stress in patients suffering from Chronic Suppurative Otitis Media. Pak J Med Sci. 2019;35(2):---------. doi: https://doi.org/10.12669/pjms.35.2.152 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals A study of complications of chronic suppurative otitis media at tertiary care hospital

2020 ◽  
Vol 6 (2) ◽  
pp. 330
Author(s):  
Bhagirathsinh D. Parmar ◽  
Sushil Jha ◽  
Vikas Sinha ◽  
Nirav Chaudhury ◽  
Gavendra Dave
Keyword(s):  
Otitis Media ◽  
Tertiary Care ◽  
Acute Otitis Media ◽  
Neck Surgery ◽  
Study Data ◽  
Chronic Suppurative Otitis Media ◽  
Common Disease ◽  
Care Hospital ◽  
Suppurative Otitis Media ◽  
Intracranial Complications

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is a still common disease in developing country and is found sometimes difficult to treat. Different complications can develop inspite of availability of higher antibiotics. In pre-antibiotic era, complications of acute otitis media and CSOM were very common and lead to high mortality. Inspite of initial decline in the complication of CSOM due to higher antibiotics, the incidences are still on rise. CSOM remains a serious disease, particularly in developing countries and CSOM-related complications are still found life-threatening. The aim and objective was to study various clinical presentations and management of CSOM related complications.</p><p class="abstract"><strong>Methods:</strong> All patients of chronic supurrative otitis media with intra or extracranial complication who were admitted in Department of Otorhinolaryngology Head and Neck surgery, Sir. T. General Hospital, Government Medical College, Bhavnagar from July 2015 to December 2018 was included in this study. Data of clinical presentation, associated complication, management, and follow-up were analysed.  </p><p class="abstract"><strong>Results:</strong> Out of 250 patients of CSOM admitted during these 3 years in ENT Department, 36 patients presented with CSOM related complications. 15 patients presented with intracranial complications and 21 patients presented with extracranial complications.</p><p class="abstract"><strong>Conclusions:</strong> Inspite of availability of higher antibiotics, CSOM related complications are still common. In all the patients require higher intravenous antibiotics (which crosses blood brain barrier) followed by mastoid surgeries.</p>

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